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SERGIO ALEJANDRO LAVANDERO GONZALEZ

Director

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

Líneas de Investigación


1. Transducción de señales en sistema cardiovascular. 2. Cardiomiopatías y diabetes. 3. Metabolismo mitocondrial. 4. Comunicación inter-organelar. 5. Angiotensina-(1-9). 6. Enfermedades cardiovasculares

Educación

  •  Bioquimica, UNIVERSIDAD DE CHILE. Chile, 1993

Experiencia Académica

  •   Adjunct Professor Other

    UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS

    Dallas, Estados Unidos

    2014 - A la fecha

  •   Profesor Titular Full Time

    UNIVERSIDAD DE CHILE

    Ciencias Quimicas y Farmaceuticas

    Santiago, Chile

    1985 - A la fecha

  •   Profesor Titular Part Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2000 - A la fecha

  •   Visiting Professor Other

    UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER

    Dallas, Estados Unidos

    2010 - 2014

Experiencia Profesional

  •   Ayudante Full Time

    UNIVERSIDAD DE CHILE-Facultad Ciencias Quimicas y Farmaceuticas

    Santiago, Chile

    1989 - 1990

  •   Instructor Full Time

    UNIVERSIDAD DE CHILE-Facultad Ciencias Quimicas y Farmaceuticas

    Santaigo, Chile

    1985 - 1999

  •   Profesor Asistente Full Time

    UNIVERSIDAD DE CHILE-Facultad Ciencias Quimicas y Farmaceuticas

    Santiago, Chile

    1991 - 1995

  •   Profesor Asociado Full Time

    UNIVERSIDAD DE CHILE-Facultad Ciencias Quimicas y Farmaceuticas

    Santiago, Chile

    1995 - 2000


 

Article (276)

Effects of Trimetazidine on Right Ventricular Function and Ventricular Remodeling in Patients with Pulmonary Artery Hypertension: A Randomised Controlled Trial
Endothelial activation impairs the function of small extracellular vesicles
Methods for studying primary cilia in heart tissue after ischemia-reperfusion injury
Myristate induces mitochondrial fragmentation and cardiomyocyte hypertrophy through mitochondrial E3 ubiquitin ligase MUL1
Organelle Communication: Joined in Sickness and in Health
Targeting VCAM-1: a therapeutic opportunity for vascular damage
The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage
Activation of Phosphodiesterase 3A: New Hope for Cardioprotection
Angiotensin-(1-9) in hypertension
Autophagy in aging-related oral diseases
IGF-1 boosts mitochondrial function by a Ca2+ uptake-dependent mechanism in cultured human and rat cardiomyocytes
Impaired AMP-Activated Protein Kinase Signaling in Heart Failure With Preserved Ejection Fraction-Associated Atrial Fibrillation
Insulin signaling in the heart is impaired by growth hormone: a direct and early event
Mitochondrial E3 ubiquitin ligase 1 (MUL1) as a novel therapeutic target for diseases associated with mitochondrial dysfunction
Mitophagy in cardiovascular diseases: molecular mechanisms, pathogenesis, and treatment
Regulation of total LC3 levels by angiotensin II in vascular smooth muscle cells
The integrated stress response in ischemic diseases
The role of autophagy in cardiovascular pathology
Circulating Vascular Cell Adhesion Molecule-1 (sVCAM-1) Is Associated With Left Atrial Remodeling in Long-Distance Runners
Cooperative Binding of ETS2 and NFAT Links Erk1/2 and Calcineurin Signaling in the Pathogenesis of Cardiac Hypertrophy
Corrigendum to "Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol" [Experimental and Molecular Pathology Volume 92, Issue 1, February 2012, Pages 97-104]
Endoplasmic reticulum-mitochondria coupling increases during doxycycline-induced mitochondrial stress in HeLa cells
Left Cardiac Remodelling Assessed by Echocardiography Is Associated with Rho-Kinase Activation in Long-Distance Runners
NAD+ Repletion Reverses Heart Failure With Preserved Ejection Fraction
Novel Insights Into the Pathogenesis of Diabetic Cardiomyopathy and Pharmacological Strategies
Novel molecular insights and public omics data in pulmonary hypertension
Perspectives on Organelle Interaction, Protein Dysregulation, and Cancer Disease
PKD2/polycystin-2 induces autophagy by forming a complex with BECN1
Polycystin-1 is required for insulin-like growth factor 1-induced cardiomyocyte hypertrophy
Polycystin-1 regulates cardiomyocyte mitophagy
Resolvin-D1 attenuation of angiotensin II-induced cardiac inflammation in mice is associated with prevention of cardiac remodeling and hypertension
Skeletal muscle type-specific mitochondrial adaptation to high-fat diet relies on differential autophagy modulation
Targeting the Endothelium to Achieve Cardioprotection
Testosterone activates glucose metabolism through AMPK and androgen signaling in cardiomyocyte hypertrophy
Vaccines against components of the renin-angiotensin system
Xbp1s-FoxO1 axis governs lipid accumulation and contractile performance in heart failure with preserved ejection fraction
Angiotensin-(1-9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway
Angiotensin-(1-9) prevents vascular remodeling by decreasing vascular smooth muscle cell dedifferentiation through a FoxO1-dependent mechanism
Angiotensin-(1–9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway
Autophagy Activation in Zebrafish Heart Regeneration
beta-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle
Calcium-Sensing Receptor in Adipose Tissue: Possible Association with Obesity-Related Elevated Autophagy
Cohort Profile: The Maule Cohort (MAUCO)
Early left atrial dysfunction is associated with suboptimal cardiovascular health
Epigenetic Reader BRD4 (Bromodomain-Containing Protein 4) Governs Nucleus-Encoded Mitochondrial Transcriptome to Regulate Cardiac Function
FoxO1-Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth
Increased production of functional small extracellular vesicles in senescent endothelial cells
Inhibition of chymotrypsin-like activity of the proteasome by ixazomib prevents mitochondrial dysfunction during myocardial ischemia
Inhibition of the proteasome preserves Mitofusin-2 and mitochondrial integrity, protecting cardiomyocytes during ischemia-reperfusion injury
Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Diseases?
Light-induced release of the cardioprotective peptide angiotensin-(1-9) from thermosensitive liposomes with gold nanoclusters
Manipulation of ACE2 expression in COVID-19
New emerging roles of Polycystin-2 in the regulation of autophagy
Preoperative soluble VCAM-1 contributes to predict late mortality after coronary artery surgery
Rho-kinase pathway activation and apoptosis in circulating leucocytes in patients with heart failure with reduced ejection fraction
Role of Autophagy in the Microenvironment of Oral Squamous Cell Carcinoma
Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-?1
Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-β1
β-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle
Angiotensin II-Regulated Autophagy Is Required for Vascular Smooth Muscle Cell Hypertrophy
AT2 Receptor Mediated Activation of the Tyrosine Phosphatase PTP1B Blocks Caveolin-1 Enhanced Migration, Invasion and Metastasis of Cancer Cells
Author Correction: Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress
Bafilomycin-A1 and ML9 Exert Different Lysosomal Actions to Induce Cell Death
Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress
Counter-regulatory renin-angiotensin system in cardiovascular disease
Editorial commentary: Cardiometabolic diseases and gut microbiota-removing the veil
Fibroblast Primary Cilia Are Required for Cardiac Fibrosis
GDF-11 prevents cardiomyocyte hypertrophy by maintaining the sarcoplasmic reticulum-mitochondria communication
Looking back and thinking forwards - 15 years of cardiology and cardiovascular research
Nitrosative stress drives heart failure with preserved ejection fraction
Polycystin-1 Assembles With Kv Channels to Govern Cardiomyocyte Repolarization and Contractility
TGF-beta 1 induced up-regulation of B1 kinin receptor promotes antifibrotic activity in rat cardiac myofibroblasts
TGF-β1 induced up-regulation of B1 kinin receptor promotes antifibrotic activity in rat cardiac myofibroblasts
The Association of Ascorbic Acid, Deferoxamine and N-Acetylcysteine Improves Cardiac Fibroblast Viability and Cellular Function Associated with Tissue Repair Damaged by Simulated Ischemia/Reperfusion
TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals
[Cardiotoxicity of anticancer therapies. Towards the implementation of cardio-oncology units]
Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension
Autophagy and oxidative stress in non-communicable diseases: A matter of the inflammatory state?
Autophagy mediates calcium-sensing receptor-induced TNFα production in human preadipocytes
Cardioprotection mediated by exosomes is impaired in the setting of type II diabetes but can be rescued by the use of non-diabetic exosomes in vitro
Down Syndrome Critical Region 1 Gene, , Helps Maintain a More Fused Mitochondrial Network.
Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioning
Herpud1 impacts insulin-dependent glucose uptake in skeletal muscle cells by controlling the Ca2+-calcineurin-Akt axis
Increased active phase atrial contraction is related to marathon runner performance
IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice
Mechanical stretch increases L-type calcium channel stability in cardiomyocytes through a polycystin-1/AKT-dependent mechanism
Nanoparticles for diagnosis and therapy of atherosclerosis and myocardial infarction: evolution toward prospective theranostic approaches
Polycystin-2-dependent control of cardiomyocyte autophagy
Potential adverse cardiac remodelling in highly trained athletes: still unknown clinical significance
Protection of the myocardium against ischemia/reperfusion injury by angiotensin-(1-9) through an AT2R and Akt-dependent mechanism
The STIM1 inhibitor ML9 disrupts basal autophagy in cardiomyocytes by decreasing lysosome content
Acute effect of iloprost inhalation on right atrial function and ventricular dyssynchrony in patients with pulmonary artery hypertension.
Acute effect of iloprost inhalation on right atrial function and ventricular dyssynchrony in patients with pulmonary artery hypertension.
Calcium Transport and Signaling in Mitochondria.
Herpud1 negatively regulates pathological cardiac hypertrophy by inducing IP3 receptor degradation
Increased C-reactive protein plasma levels are not involved in the onset of post-operative atrial fibrillation.
Mitochondria in Structural and Functional Cardiac Remodeling.
Sarcoplasmic reticulum-mitochondria communication in cardiovascular pathophysiology
Sarcoplasmic reticulum-mitochondria communication in cardiovascular pathophysiology
Subcellular Remodeling of the T-Tubule Membrane System=> The Limits of Myocardial Recovery Revealed?
Atrial Function Assessed by Speckle Tracking Echocardiography Is a Good Predictor of Postoperative Atrial Fibrillation in Elderly Patients
BAG3 regulates total MAP1LC3B protein levels through a translational but not transcriptional mechanism
Calcium Sensing Receptor as a Novel Mediator of Adipose Tissue Dysfunction: Mechanisms and potential Clinical Implications
Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism
FoxO1 mediates TGF-beta1-dependent cardiac myofibroblast differentiation
HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor
Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells.
Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression
Rapamycin requires AMPK activity and p27 expression for promoting autophagy-dependent Tsc2-null cell survival
Regulation of cardiomyocyte autophagy by calcium.
Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024
Therapeutic targeting of autophagy in myocardial infarction and heart failure.
TonEBP suppresses IL-10-mediated immunomodulation
FK866 compromises mitochondrial metabolism and adaptive stress responses in cultured cardiomyocytes
Glutathione Depletion Induces Spermatogonial Cell Autophagy
Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells
Novel Nanostructured Polymeric Carriers to Enable Drug Delivery for Cardiovascular Diseases
Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability
Role of Akt and Ca2+ on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition
Unsaturated fatty acids induce non-canonical autophagy
Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system.
4-Phenylbutyric acid prevent cytotoxicity induced by thapsigargin in rat cardiac fibroblast
A novel dihydropyridine with 3-aryl meta-hydroxyl substitution blocks L-type calcium channels in rat cardiomyocytes
Alteration in mitochondrial Ca2+ uptake disrupts insulin signaling in hypertrophic cardiomyocytes
Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis
Ca2+ signals promote GLUT4 exocytosis and reduce its endocytosis in muscle cells
Dexamethasone-induced autophagy mediates muscle atrophy through mitochondrial clearance
Effects of Trimetazidine in Nonischemic Heart Failure: A Randomized Study
Histone Deacetylase Inhibition Blunts Ischemia/Reperfusion Injury by Inducing Cardiomyocyte Autophagy
Insulin elicits a ROS-activated and an IP3-dependent Ca2+ release, which both impinge on GLUT4 translocation
Insulin Stimulates Mitochondrial Fusion and Function in Cardiomyocytes via the Akt-mTOR-NF kappa B-Opa-1 Signaling Pathway
Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway
Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake
Organelle communication: Signaling crossroads between homeostasis and disease
Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics
Role of Heterotrimeric G Protein and Calcium in Cardiomyocyte Hypertrophy Induced by IGF-1
Serotonin (5-HT) Regulates Neurite Outgrowth Through 5-HT1A and 5-HT7 Receptors in Cultured Hippocampal Neurons
Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway
Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway.
Trimetazidine prevents palmitate-induced mitochondrial fission and dysfunction in cultured cardiomyocytes
Calcium and mitochondrial metabolism in ceramide-induced cardiomyocyte death
Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy
Cell Death and Survival Through the Endoplasmic Reticulum-Mitochondrial Axis
Electrical Stimuli Release ATP to Increase GLUT4 Translocation and Glucose Uptake via PI3K gamma-Akt-AS160 in Skeletal Muscle Cells
Endocytic pathway of exogenous iron-loaded ferritin in intestinal epithelial (Caco-2) cells
Herp depletion protects from protein aggregation by up-regulating autophagy
Local Control of Nuclear Calcium Signaling in Cardiac Myocytes by Perinuclear Microdomains of Sarcolemmal Insulin-Like Growth Factor 1 Receptors
Testosterone Increases GLUT4-Dependent Glucose Uptake in Cardiomyocytes
TGF-beta 1 prevents simulated ischemia/reperfusion-induced cardiac fibroblast apoptosis by activation of both canonical and non-canonical signaling pathways
A BAX/BAK and Cyclophilin D-Independent Intrinsic Apoptosis Pathway
Apoptosis, necrosis and autophagy are influenced by metabolic energy sources in cultured rat spermatocytes
Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol
Dexmedetomidine preconditioning activates pro-survival kinases and attenuates regional ischemia/reperfusion injury in rat heart
Differential regulation of collagen secretion by kinin receptors in cardiac fibroblast and myofibroblast
Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics
Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy
ICDS 2011 meeting 'Signaling in cell death survival, proliferation and degeneration'
Impaired cardiac autophagy in patients developing postoperative atrial fibrillation
Mayores niveles de ECA y Angiotensina II determinados genéticamente, se asocian a menor actividad del eje ECA2/angiotensina-(1-9) y mayor remodelamiento de la pared aórtica de ratas hipertensas
Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice
Mitochondria, Myocardial Remodeling, and Cardiovascular Disease
NFAT5 Is Activated by Hypoxia: Role in Ischemia and Reperfusion in the Rat Kidney
Protein Carbonylation and Adipocyte Mitochondrial Function
Relationship between mechanical and metabolic dyssynchrony with left bundle branch block: Evaluation by 18-fluorodeoxyglucose positron emission tomography in patients with non-ischemic heart failure
Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability
Anabolic androgenic steroids and intracellular calcium signaling: A mini review on mechanisms and physiological implications.
Beta(2)-adrenergic receptor regulates cardiac fibroblast autophagy and collagen degradation
Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress
Inhibition of autophagy by TAB2 and TAB3
Left Atrial Dysfunction Is a Predictor of Postcoronary Artery Bypass Atrial Fibrillation: Association of Left Atrial Strain and Strain Rate Assessed by Speckle Tracking
Markedly increased Rho-kinase activity in circulating leukocytes in patients with chronic heart failure
Mayor actividad de rho kinasa en leucocitos circulantes se asocia a estrés oxidativo y rigidez arterial en hipertensos diabéticos
Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1-9) axis in experimental hypertension
Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts
Systemic Oxidative Stress and Endothelial Dysfunction is Associated With an Attenuated Acute Vascular Response to Inhaled Prostanoid in Pulmonary Artery Hypertension Patients
Systemic vascular cell adhesion molecule-1 predicts the occurrence of post-operative atrial fibrillation
The complex interplay between mitochondrial dynamics and cardiac metabolism
The role of uric acid in heart failure
The role of uric acid in heart failure Ácido úrico: Una molécula con acciones paradójicas en la insuficiencia cardiaca
Xanthine-oxidase inhibitors and statins in chronic heart failure: Effects on vascular and functional parameters
An Inositol 1,4,5-Triphosphate (IP3)-IP3 Receptor Pathway Is Required for Insulin-Stimulated Glucose Transporter 4 Translocation and Glucose Uptake in Cardiomyocytes
Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro
Calpains and proteasomes mediate degradation of ryanodine receptors in a model of cardiac ischemic reperfusion
Contraction-related stimuli regulate GLUT4 traffic in C2C12-GLUT4myc skeletal muscle cells
Determinaciones de niveles de creatina y lípidos mediante espectroscopia por resonancia magnética en miocardio de pacientes con insuficiencia cardiaca no isquémica
Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes
Heart energy metabolism and its role in the treatment of heart failure Metabolismo energético del corazón y sus proyecciones en el tratamiento de la insuficiencia cardíaca
Increased levels of oxidative stress, subclinical inflammation, and myocardial fibrosis markers in primary aldosteronism patients
Insulin-Mediated GLUT4 Translocation Requires Intracellular and Extracellular Calcium and is Impaired by Short-Term High Fat Feeding
Iron induces protection and necrosis in cultured cardiomyocytes: Role of reactive oxygen species and nitric oxide
La sobreexpresión del gen de enzima convertidora de angiotensina homóloga (ECA2) revierte la hipertensión arterial y el remodelado cardíaco experimental
Menores niveles tisulares de la enzima convertidora de angiotensina I homologa (ECA-2) y angiotensina-(1-9) están asociados a mayor remodelamiento de la pared aórtica de ratas hipertensas
Mitochondria fine-tune the slow Ca2+ transients induced by electrical stimulation of skeletal myotubes
Mitochondrial Fission and Autophagy in the Normal and Diseased Heart
Myocardial lipids and creatine measured by magnetic resonance spectroscopy among patients with heart failure Determinaciones de niveles de creatina y lípidos mediante espectroscopia por resonancia magnética en miocardio de pacientes con insuficiencia cardiaca no isquémica
Niveles aumentados de estrés oxidativo se asocian a disfunción endotelial periférica y respuesta vascular pulmonar disminuida frente a vasodilatadores en pacientes con hipertensión pulmonar
Parallel activation of Ca2+-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress
The IKK complex contributes to the induction of autophagy
(TTA)n Polymorphism in 3-Hydroxy-3-Methylglutaryl-Coenzyme A and Response to Atorvastatin in Coronary Artery Disease Patients
Differential Participation of Angiotensin II Type 1 and 2 Receptors in the Regulation of Cardiac Cell Death Triggered by Angiotensin II
El tratamiento con atorvastatina reduce la actividad de xantina-oxidasa unida al endotelio en pacientes con insuficiencia cardíaca crónica: ¿Un posible nuevo efecto pleiotrópico?
Ex vivo method to visualize and quantify vascular networks in native and tissue engineered skin
Gln(27)-> Glu beta(2)-Adrenergic Receptor Polymorphism in Heart Failure Patients: Differential Clinical and Oxidative Response to Carvedilol
Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alpha v beta 3 integrin that activates PKC alpha and RhoA
Regulatory volume decrease in cardiomyocytes is modulated by calcium influx and reactive oxygen species
Testosterone induces cardiomyocyte hypertrophy through mammalian target of rapamycin complex 1 pathway
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1
The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling
The use of glandular-derived stem cells to improve vascularization in scaffold-mediated dermal regeneration
Trypanosoma cruzi calreticulin: A possible role in Chagas' disease autoimmunity
Use of Human Mesenchymal Cells to Improve Vascularization in a Mouse Model for Scaffold-Based Dermal Regeneration
Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells
Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis
Early expression of monocyte chemoattractant protein-1 correlates with the onset of isoproterenol-induced cardiac fibrosis in rats with distinct angiotensin-converting enzyme polymorphism
Osmotically-induced genes are controlled by the transcription factor TonEBP in cultured cardiomyocytes
Phospholipase C/protein kinase C pathway mediates angiotensin II-dependent apoptosis in neonatal rat cardiac fibroblasts expressing AT1 receptor
Pleiotropic effects of atorvastatin in heart failure: Role in oxidative stress, inflammation, endothelial function, and exercise capacity
Senescence, apoptosis or autophagy?
Serum uric acid correlates with extracellular superoxide dismutase activity in patients with chronic heart failure
Subclinical endothelial inflammation markers in a family with type I familial hyperaldosteronism caused by a de novo mutation
Mitochondrial control of cell death induced by hyperosmotic stress
Regulation of autophagy by the inositol trisphosphate receptor
Rho kinase activation and gene expression related to vascular remodeling in normotensive rats with high angiotensin I-converting enzyme levels
The inositol trisphosphate receptor in the control of autophagy
Tumor necrosis factor-? activates nuclear factor-?B but does not regulate progesterone production in cultured human granulosa luteal cells
Tumor necrosis factor-alpha activates nuclear factor-kappa B but does not regulate progesterone production in cultured human granulosa luteal cells
Effect of hypertension on angiotensin-(1-7) levels in rats with different angiotensin-I converting enzyme polymorphism
Enalapril attenuates downregulation of angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat
Hyperosmotic stress activates p65/RelB NF kappa B in cultured cardiomyocytes with dichotomic actions on caspase activation and cell death
Hyperosmotic stress-dependent NF kappa B activation is regulated by reactive oxygen species and IGF-1 in cultured cardiomyocytes
Membrane electrical activity elicits inositol 1,4,5-trisphosphate-dependent slow Ca2+ signals through a G beta gamma/phosphatidylinositol 3-kinase gamma pathway in skeletal myotubes
Reactive oxygen species inhibit hyposmotic stress-dependent volume regulation in cultured rat cardiomyocytes
Testosterone induces an intracellular calcium increase by a nongenomic mechanism in cultured rat cardiac myocytes
Effects of carvedilol on oxidative stress and chronotropic response to exercise in patients with chronic heart failure
Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure
Eplerenone blocks nongenomic effects of aldosterone on the Na+/H+ exchanger, intracellular Ca2+ levels, and vasoconstriction in mesenteric resistance vessels
IGF-1 protects cardiac myocytes from hyperosmotic stress-induced apoptosis via CREB
Increased aortic NADPH oxidase activity in rats with genetically high angiotensin-converting enzyme levels
Oxidative stress in pericardial fluid and plasma and its association with ventricular function
Perindopril regulates ?-agonist-induced cardiac apoptosis
Perindopril regulates beta-agonist-induced cardiac apoptosis
Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure
Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure Efectos del carvedilol en la capacidad funcional, función ventricular izquierda, catecolaminas y estrés oxidativo en pacientes con insuficiencia cardíaca crónica
Ethanol increases tumor necrosis factor-alpha receptor-1 (TNF-R1) levels in hepatic, intestinal, and cardiac cells
Insulin-like growth factor-1 induces an inositol 1,4,5-trisphosphate-dependent increase in nuclear and cytosolic calcium in cultured rat cardiac myocytes
Neutral endopeptidase and angiotensin I converting enzyme insertion/deletion gene polymorphism in humans
Polymorphism in gene coding for ACE determines different development of myocardial fibrosis in rats
Aldose reductase induced by hyperosmotic stress mediates cardiomyocyte apoptosis - Differential effects of sorbitol and mannitol
IGF-1 modulation of rat cardiac fibroblast behavior and gene expression is age-dependent
Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-1-converting enzyme deletion/deletion genotype
Relation between oxidative stress, catecholamines, and impaired chronotropic response to exercise in patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
Angiotensin I-converting enzyme gene polymorphism influences chronic hypertensive response in the rat Goldblatt model
Angiotensin I-converting enzyme insertion/deletion polymorphism and adrenergic response to exercise in hypertensive patients
Effects of early decrease in oxidative stress after medical therapy in patients with class IV congestive heart failure
Isoproterenol and angiotensin I-converting enzyme in lung, left ventricle, and plasma during myocardial hypertrophy and fibrosis
Oxidative stress after reperfusion with primary coronary angioplasty: Lack of effect of glucose-insulin-potassium infusion
Persistence of oxidative stress after heart tranplantation: A comparative study of patients with heart transplant versus chronic stable heart failure
Persistence of oxidative stress after heart transplantation: A comparative study of patients with heart transplant versus chronic stable heart failure
A rapid and strong apoptotic process is triggered by hyperosmotic stress in cultured rat cardiac myocytes
Angiotensin I-converting enzyme modulates neutral endopeptidase activity in the rat
Early prevention of experimental left ventricular hypertrophy in experimental hypertension and angiotensin II levels
Extracellular regulated kinase, but not protein kinase C, is an antiapoptotic signal of insulin-like growth factor-1 on cultured cardiac myocytes
IGF-1 regulates apoptosis of cardiac myocyte induced by osmotic-stress
Effects of antihypertensive treatment on cardiac IGF-1 during prevention of ventricular hypertrophy in the rat
Prevalence of the angiotensin I converting enzyme insertion/deletion polymorphism, plasma angiotensin converting enzyme activity, and left ventricular mass in a normotensive Chilean population
Effect of inhibitors of signal transduction on IGF-1-induced protein synthesis associated with hypertrophy in cultured neonatal rat ventricular myocytes
In vivo and in vitro evidence of basic fibroblast growth factor action in mouse mammary gland development
Selective increase in cardiac IGF-1 in a rat model of ventricular hypertrophy
IGF-1 activates polyphosphoinositide hydrolysis, protein kinase C isoforms and ERK pathway in cultured neonatal rat cardiac myocytes
Insulin-like growth factor-I rapidly activates multiple signal transduction pathways in cultured rat cardiac myocytes
Omeprazole, a specific gastric secretion inhibitor on oxynticopeptic cells, reduces gizzard erosion in broiler chicks fed with toxic fish meals
Cyclic AMP dependent protein kinase and mechanical heart function in ventricular hypertrophy induced by pressure overload or secondary to myocardial infarction
Synthesis and pharmacological effects of 3-methyl tyrphostin (2-cyano- 3-[4-hydroxyphenyl]-2-butenethioamide): A new protein tyrosine kinase inhibitor
A potential role of autophagy-mediated vascular senescence in the pathophysiology of HFpEF
Polycystin-2 Is Required for Starvation- and Rapamycin-Induced Atrophy in Myotubes
VCAM-1 as a predictor biomarker in cardiovascular disease

Abstract (48)

Glutathione depletion in spermatogonia-type germ cells: Autophagy and Ago2 function
FoxO1 switches energy metabolism and stimulates mitochondrial fission in myocardial insulin resistance.
Angiotensin-(1-9) Decreases Hypertension and Vascular Damage by Inhibiting Rhoa/rock Activity in Doca Hypertensive Rats
FoxO1 Ablation Rescues Metabolic Stress-induced Cardiac Remodeling
Germ cell autophagy: adaptive response to glutathione deficiency
HDAC-Dependent Regulation of Pathological Hypertrophy
Herp protects Hela cells from oxidative stress-induced cell death
Insulin Induces both H2O2 Production and IP3-Dependent Mitochondria Ca2+ Uptake. H2O2 Oxidizes RyR to Elicit Ca2+ Release and GLUT4 Translocation in Skeletal Muscle Cells
Polycystin 2 is Required for Stress-induced Activation of Autophagy in Heart
Polycystin-1 Regulates Cardiac Hypertrophy via the L-type Calcium Channel
Effect of proinflammatory cytokines on mitochondrial function in 3T3-L1 adipocytes
NAD(P)H oxidase-dpendent H2O2 production and RyR-IP3R activation are required for insulin induced GLUT4 translocation and glucose uptake in skeletal muscle cells
New insights into insulin action in the heart
Angiotensin-(1-9) Prevents Cardiomyocyte Hypertrophy Through Calcium Influx Dependent Pathway
Angiotensin-(1-9) Prevents the Cardiovascular Pathological Remodeling Induced by Angiotensin II In Vivo
Evidence of impaired cardiac autophagic flux in patients developing post-operative atrial fibrillation
Persistent Activation of FoxO Contributes to Insulin Resistance and Diabetic Cardiomyopathy
Increased Oxidative Stress Correlates With Pulmonary Vascular Response to Vasodilators in Pulmonary Artery Hypertension Patients
MITOCHONDRIA MODULATE INTRACELLULAR CALCIUM SIGNALS THAT CONTROL ATP TRANSIENTS INDUCED BY ELECTRICAL STIMULATION OF SKELETAL MYOTUBES
Use of pancreas-derived stem cells to improve vascularization in skin tissue engineering
Angiotensin II triggers apoptosis in cardiac fibroblast but not in myofibroblast overexpressing the type 1 receptor
Effects of atorvastatin therapy in heart failure: Oxidative stress, inflammation, endothelial dysfunction and exercise capacity
Inflammation and endothelial dysfunction in patients with chronic heart failure
Mitochondrial Ca2+ transients upon electrical stimulation of skeletal myotubes
Up-regulation of ACE2 by enalapril is associated to lower cardiac remodeling in myocardial infarcted rat
Activity of metalloproteinase-9 is related to oxidative stress in the acute coronary syndrome
Carvedilol corrects interventricular and interventricular dyssynchrony in chronic heart failure.
Apoptosis induced by hyperosmotic stress
Decrease in oxidative stress is not related to left ventricular function improvement in patients with chronic heart failure treated with carvedilol
Early expression of vascular transforming growth factor beta 1 (TGF beta 1) in DOCA-salt rats
Gene expression of profibrotic factors in isoproterenol-treated Brown-Norway and Lewis rats
IGF-1 prevents NF kappa B activation but not reactive oxygen species generation by hyperosmotic stress in apoptotic cultured cardiac myocytes
Influence of angiotensin-I converting enzyme polymorphism in the isoproterenol-induced extracellular matrix proteins deposition by cardiac fibroblasts.
The Arg389Arg adrenergic receptor variant interacts with the Arg16Arg and Gly27Gly beta 2 adrenergic receptor variants decreasing the risk for chronic heart failure
Angiotensin converting enzyme polymorphism determines differential acumulation of cardiac extracelular matrix protein induced by isoproterenol in the rat
beta 1 and beta 2-adrenergic receptor gene polymorphisms are not associated with heart failure
Hyperosmotic stress induces oxidative stress and NF kappa B activation in cultured cardiac myocytes
beta(2)-adrenergic receptor polymorphisms are not associated with heart failure
Ethnic differences in beta 2 adrenergic receptor polymorphisms distribution
IGF-1 modulates cardiac fibroblast migration and adhesion through the expression and synthesis of alpha 1, beta 1-integrin and collagen
Neutral endopeptidase and angiotensin I converting enzyme insertion/deletion gene polymorphism in normotensive and hypertensive subjects
Angiotensin I-converting enzyme gene polymorphism modulates chronic hypertensive response in the rat Goldblatt model
IGF-1 regulates integrin and collagen expression and cell-ECM interactions on cultured rat cardiac fibroblasts
Myocardial angiotensin II generation and the angiotensin I - converting enzyme gene polymorphism in the rat
PI3-K/PKB pathway on the antiapoptotic response of IGF-1 in cardiac myocytes
Tissue neutral endopeptidase activity is inversely related to angiotensin I-converting enzyme expression in the rat
Early decrease in oxidative stress in patients with class IV heart failure after successfull medical therapy
Gene transcription associated to cardiomyocyte hypertrophy is differentially regulated by IGF-1

BookWhole (3)

Sarcoplasmic reticulum and calcium signaling in muscle cells: Homeostasis and disease
Autophagy in cardiac physiology and disease
Regulation of autophagy by insulin/IGF-1 signaling pathways

Comentario (1)

Polimorfismo Pro 72Arg del gen TP53 y enfermedad coronaria

ComunicacionBreve (1)

Ácido úrico: una molécula con acciones paradójicas en la insuficiencia cardiaca

EditorialMaterial (6)

Heart Disease and Cancer: Are the Two Killers Colluding?
Parkin Gone Wild Unbridled Ubiquitination
Regulation of Cardiovascular Metabolism by Hormones and Growth Factors
Signaling in Cell Death, Survival, Proliferation and Degeneration
IKK connects autophagy to major stress pathways
Mechanisms of cell death: molecular insights and therapeutic perspectives

Errata (1)

Mitochondrial control of cell death induced by hyperosmotic stress (vol 12, pg 3, 2007)

Generic (1)

Science and Health Policies to Tackle Chronic Diseases in Chile

Letter (4)

Female Sex Is Protective in a Preclinical Model of Heart Failure With Preserved Ejection Fraction
Dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure Reply
Matrix metalloproteinase-9 activity is associated to oxidative stress in patients with acute coronary syndrome
Uric acid, xanthine oxidase and heart failure: Unresolved issues

Proyecto (22)

Advanced Center for Chronic Diseases (ACCDiS)
EVALUATION OF RIGHT VENTRICULAR FUNCTION, VENTRICULAR REMODELING AND MICRO RNA PROFILING IN PATIENTS WITH PULMONARY ARTERY HYPERTENSION=> EFFECTS OF A FATTY ACID OXIDATION INHIBITOR
NOGO-B ESTIMULA EL ACOPLAMIENTO ESTRUCTURAL Y FUNCIONAL RET�CULO ENDOPLASM�TICO-MITOCONDRIA DURANTE UNA SITUACIÓN DE ESTRÉS DEL RET�CULO EN CÉLULAS HELA
THE PROGNOSTIC ROLE OF LEFT ATRIAL AND VENTRICULAR FUNCTION AND ITS CORRELATION WITH MULTIPLE BIOMARKERS IN PATIENTS WITH NEW ATRIAL FIBRILLATION
THE ROLE OF STIM1-ORAI1 ON THE REGULATION OF CARDIOMYOCYTE AUTOPHAGY
"EFFECT OF PROTEASOME INHIBITION ON THE CONTENT OF MITOFUSINS 1 AND 2 AND THE PRESERVATION OF MITOCHONDRIAL FUNCTION FOLLOWING CARDIAC ISCHEMIA-REPERFUSION"
Effect of proteasome inhibition on the content of mitofusins 1 and 2 and the preservation of mitochondrial function following cardiac ischemia-reperfusion"
ESTUDIO DE ADENOSINA Y SU SISTEMA TRANSDUCCIONAL EN LA CARDIOMIOPATIA DIABETICA.
MODULACION DE LA AUTOFAGIA POR EL RECEPTOR DE INOSITOL TRIFOSFATO (IP3R) EN DISTROFIA MUSCULAR DE DUCHENNE.
Apoyo a la formación de redes internacionales entre centros de investigación
REGULATION OF MITOCHONDRIAL DYNAMICS AND BIOENERGETICS BY INSULIN IN CARDIOMYOCYTES
PAPEL DEL FACTOR TRANSCRIPCIONAL FOXO1 EN LA REGULACION DEL METABOLISMO Y LA DINAMICA MITOCONDRIAL INDUCIDA POR INSULINA.
ROLE OF MYOCARDIAL CELLULAR ADHESION MOLECULES (VCAM-1/ICAM-1) IN CARDIOPROTECTIVE ACTIONS OF INSULIN
GLUCOCORTICOIDES EN LA INDUCCION DE AUTOFAGIA EN CELULAS MUSCULARES . PAPEL DE LA VIA NO GENOMICA EN LA ATROFIA MUSCULAR
Metabolismo cardiaco en la insuficiencia cardiaca crónica no isquémica y sus implicancias en el estrés oxidativo, inflamación y remodelado cardiovascular.
Proyecto ECOS-CONICYT=> Mecanismos de transducción de señales en la autofagia. Dr Guido Kroemer (Francia).
Efecto de la dinámica mitocondrial sobre la biología muscular.
En la hipertensión arterial con alto riesgo cardiovascular la activación de Rho kinasa media el remodelado patológico=> un estudio clínico y molecular experimental
RESISTENCIA A INSULINA EN LA DIABETES TIPO II=> ESTUDIO DE NUEVOS MECANISMOS FISIOPATOLOGICOS ASOCIADOS AL DETERIORO DE LA FUNCION CARDIACA
Resistencia a insulina en la diabetes tipo II=> estudio de nuevos mecanismos fisiopatológicos asociados al deterioro de la función cardiaca
Rol del estrés oxidativo y de la inflamación local y sistémica en el desarrollo de fibrilación auricular en el post operatorio de cirugía cardiaca
Center for Molecular Studies of the Cell

Review (33)

Counter-regulatory renin–angiotensin system in cardiovascular disease
Emerging role of mitophagy in cardiovascular physiology and pathology
Looking back and thinking forwards-15 years of cardiology and cardiovascular research
Mitochondrial dynamics, mitophagy and cardiovascular disease
New Molecular Insights of Insulin in Diabetic Cardiomyopathy
ACE2 and vasoactive peptides: Novel players in cardiovascular/renal remodeling and hypertension
Autophagy in cardiovascular biology
Defective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy
ER-to-mitochondria miscommunication and metabolic diseases
Molecular Mechanisms of Autophagy in the Cardiovascular System
Novel players in cardioprotection: Insulin like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9)
Calcium signaling in insulin action on striated muscle
New insights into IGF-1 signaling in the heart
Oxidative Stress and Autophagy in Cardiovascular Homeostasis
Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system
Tumor Suppression and Promotion by Autophagy
Cardiovascular autophagy Concepts, controversies, and perspectives
Diabetic cardiomyopathy and metabolic remodeling of the heart
Endoplasmic Reticulum and the Unfolded Protein Response: Dynamics and Metabolic Integration
Regulation of cardiac autophagy by insulin-like growth factor 1
Guidelines for the use and interpretation of assays for monitoring autophagy
Anabolic Androgenic Steroids and Intracellular Calcium Signaling: A Mini Review on Mechanisms and Physiological Implications
Autophagy as a therapeutic target in cardiovascular disease
Cardiomyocyte death: mechanisms and translational implications
Mitochondrial Dynamics: a Potential New Therapeutic Target for Heart Failure
Tuning flux: autophagy as a target of heart disease therapy
Ca2+, autophagy and protein degradation: Thrown off balance in neurodegenerative disease
Diabetic cardiomyopathy: Mechanisms and therapeutic targets
Heart energy metabolism and its role in the treatment of heart failure
Infarto perioperatorio en cirugía no-cardíaca y dexmedetomidina
Metabolismo energético del corazón y sus proyecciones en el tratamiento de la insuficiencia cardíaca
Oxidative stress and inflammation in heart failure: Mechanisms of damage and therapeutic alternatives
Rho/Rho kinase signal transduction pathway in cardiovascular disease and cardiovascular remodeling
364
SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

107
Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

39
JORGE JALIL

FULL PROFESSOR

ENFS CARDIOVASCULARES

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, ESCUELA DE MEDICINA

Santiago, Chile

38
Maria Ocaranza

Asociate Professor

Cardiovascular Diseases Division

Pontificia Universidad Catolica de Chile

Santiago, Chile

38
Lorena Garcia

Assistant Professor

Bioquimica y Biologia Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

35
Rodrigo Troncoso

Associate Professor

Instituto de Nutrición y Tecnología de los Alimentos

Santiago, Chile

32
Hugo Verdejo

Profesor Asociado

División de Enferemedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

28
Alfredo Criollo

Associated Professor

Research Institute in Dental Sciences

Facultad de Odontología, Universidad de Chile

Santiago, Chile

27
Ramon Corbalan

Director

Division of Cardiovascular Diseases

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

27
Rodrigo Troncoso

Assistant professor

Universidad de Chile, Instituto de Nutrición y Tecnología de los Alimentos

Santiago de Chile, Chile

24
Clara Quiroga

Profesor Asistente Adjunto

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

23
Douglas Greig

Médico Jefe

Cardiología

P. Universidad Católica de Chile

Santiago, Chile

22
Pablo Castro

JEFE DIVISION

DIVISION ENFERMEDADES CARDIOVASCULARES

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

21
Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

21
Roberto Bravo

Assistant Professor

Institute of Nutrition and Food Technology (INTA), Universidad de Chile

Santiago, Chile

18
Zully Pedrozo

Associated Professor

Physiology and Biophysical

Universidad de Chile

SANTIAGO DE CHILE, Chile

14
Ariel Contreras

assistance professor

Institute for Research in Dental Science

UNIVERSIDAD DE CHILE

Santiago, Chile

13
Rosemarie Mellado

Jefe de carrera / Académica

Farmacia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

11
Veronica Eisner

Associate Professor

Cellular and Molecular Biology

Pontificia Universidad Católica de Chile

Santiago, Chile

11
Raúl Vivar

Profesor Asistente

Universidad de Chile

Santiago, Chile

10
Gina Sanchez

Profesor Asociado

ICBM

UNIVERSIDAD DE CHILE, FAC MEDICINA , ICBM

Santiago, Chile

10
Samuel Cordova

ESCUELA DE MEDICINA, PONTIFICA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

10
Jaime Riquelme

Assistant Professor

Química Farmacológica y Toxicológica

Universidad de Chile

Santiago, Chile

9
Andrea del Campo

Profesor Asistente, Investigador Principal

Departamento de Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

9
Manuel Estrada

/Associate Professor / PI

Physiology and Biophysics

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS (ICBM), PROGRAMA DE FISIOLOGÍA Y BIOFÍSICA

Santiago, Chile

9
Pablo Aránguiz

Jefe de Carrera

Escuela de Ciencias de la Salud

Universidad Vina del Mar

Viña del Mar, Chile

9
M. Cecilia Hidalgo

Professor

ICBM

Universidad de Chile

Santiago, Chile

7
Luigi Gabrielli

Profesor Asistente

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile

7
Jovan Kuzmicic

Profesor Asistente

Departamento Salud

Universidad de Los Lagos

Osorno, Chile

5
Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

5
Mauricio Ibacache

Profesor Asociado

Pontificia Universidad Católica de Chile

santiago centro, Chile

5
Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

5
Ivonne Olmedo

Assistant Profesor

Programa de Fisiopatología

Universidad de Chile

Santiago, Chile

5
Roberto Ebensperger

Associate Professor

Pharmacy

Pontificia Universidad Católica de Chile

Santiago, Chile

5
Anita Gálvez

Profesor Asistente

Biomédico

Universidad de Antofagasta

Antofagasta, Chile

4
Guillermo Díaz

Académico

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

4
Juan Carlos Quintana

Médico nuclear

Radiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

4
Eugenia Morselli

Profesor Asociado de Planta Ordinaria

Fisiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago de Chile, Chile

4
claudio olea

Full Professor

Inorganica y Analitica

UNIVERSIDAD DE CHILE

Santiago, Chile

4
Jose Egana

Profesor asociado

Instituto de Ingeniería Biológica y Médica

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

4
Rodrigo Valenzuela

Postdoctorado

Oftalmología

Universidad de Chile

Santiago, Chile

4
Berta Espinosa

Full Professor

Tecnología Médica

Universidad de Chile

Santiago, Chile

4
Leticia Gonzalez

Profesional Apoyo a la Investigacion

Pontificia Universidad Católica de Chile

Santiago, Chile

4
César Osorio

Associate Professor

Kinesiología

Universidad Metropolitana de Ciencias de la Educación

Santiago, Chile

4
Valeria Garrido

Investigador Postdoctoral

Advanced Center for Chronic Disease

Universidad de Chile

Santiago, Chile

4
Lisette Leyton

Full Professor

Cell and Molecular Biology

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

4
Mariana Cifuentes

Professor

Instituto de Nutricion y Tecnologia de los Alimentos

INTA UNIVERSIDAD DE CHILE

Santiago, Chile

3
MANUEL VARAS

Research Professor

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

3
Marco Nuñez

Professor

Biology

Fac. Ciencias, Universidad de Chile

Santiago, Chile

3
Carlos Fardella

Profesor Titular

Endocrinología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

3
Yenniffer Ávalos

Profesor Asistente

Departamento de Biología

Universidad de Santiago de Chile

Santiago, Chile

3
CLAUDIA BAMBS

PROFESORA ASOCIADA

SALUD PÚBLICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

3
Carolina Nazzal

Profesor Asociado

Instituto de Salud Poblacional

Universidad de Chile

Santiago, Chile

3
Karina Cereceda

Investigador post doctoral

Diagnóstico

Fundación Arturo López Pérez

Providencia, Chile

2
Natalia Diaz

Postdoctoral Fellow

Biofísica y Bioingeniería

Universidad de Barcelona

Barcelona , España

2
Andres Stutzin

Full Professor

ICBM

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

2
fresia ferreccio

Full Professor, Director PhD Epidemiolgy Program

Public Health

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE FACULTAD DE MEDICINA, ESCUELA DE MEDICINA, DEPARTAMENTO DE SALUD PÚBLICA.

Santiago, Chile

2
Tatiana Adasme

Coordinadora de Estudios

Oficina de Apoyo a la Investigación Clínica

Universidad Chile

Santiago, Chile

2
Carlos Vio

Profesor

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Andrew Quest

Full Professor

Biologia Celular y Molecular

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

2
Renatto Anfossi

Coordinador de Investigación

Unidad de Investigación

Hospital Regional Libertador Bernardo O'Higgins

Rancagua, Chile

2
Pablo Irarrazaval

Professor

Electrical Engineering

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Pablo Sepúlveda

Cardiólogo Intervencionista

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Claudia Muñoz

Postdoctorado

Universidad de Chile

Santiago, Chile

2
Valentina Parra

Profesora Asistente / Assistant Professor

Departamento de Bioquímica y Biología Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Mario Bustamante

Docente

Universidad Mayor de Chile

Santiago, Chile

2
Daniel Peña

Investigador postdoctoral

Departamento de Fisiología

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Cristian Carvajal

Associate Professor

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

2
Pedro Ayala

Profesor investigador asistente

Departamento de Enfermedades Respiratorias

Pontificia Universidad Católica de Chile

Santiago, Chile

2
Paulina Donoso

Full Professor

Physiology and Biophysics

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Jorge Ferreira

Director

Clinic and Molecular Farmacology

UNIVERSIDAD DE CHILE , FACULTAD DE MEDICINA, ICBM

Santiago, Chile

2
ALEJANDRA SAN MARTIN

Professor

Medicine

Universidad Andrés Bello

Santiago, Chile

2
Dagoberto Soto

Investigador

Universidad Católica de Chile

santiago, Chile

2
JUAN VILLENA

FULL PROFESSOR

ANATOMY

FACULTA DE MEDICINA. UNIVERSIDAD DE VALPARAISO

VIÑA DEL MAR, Chile

2
LORENA AGUILAR

Assistant Professor

Animal Pathology

Faculty of Veterinary Medicine and Livestock Sciences, University of Chile

Santiago, Chile

2
Matias Monsalves

Profesor Asistente

Instituto de Ciencias de la Rehabilitación

Universidad Andrés Bello

Santiago, Chile

2
Vicente Torres

Associate Professor

Institute for Research in Dental Sciences

FACULTAD DE ODONTOLOGÍA - UNIVERSIDAD DE CHILE

Santiago, Chile

2
Laura Huidobro

Encargada Investigación

Ciencias Preclínicas

Universidad Católica del Maule

Talca, Chile

1
Paula Valenzuela

Senior Researcher

Nuevos Materiales Avanzados

Leitat Chile

Santiago, Chile

1
Lorena Lobos

Principal Investigator-Associate Proffesor

Facultad of Medicine - Clinic Alemana

Universidad Del Desarrollo

santiago, Chile

1
Maria Lisbona

Postdoctorado

Biología

Universidad de Chile

Santiago, Chile

1
Lorena Mosso

profesor titular

endocrinologia

Pontificia Universidad Catolica de Chile

santiago, Chile

1
Luis Barros

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS

Valdivia, Chile

1
MARIA MOLINA

Director

Instituto de Ciencias Biomédicas

Universidad de Chile

INDEPENDENCIA, Chile

1
Ismael Maldonado

Asistente de Investigación

Inmunología

Universidad de Chile

Santiago, Chile

1
Javier Morales

Profesor Asociado

Departamento de Ciencias y Tecnología Farmacéuticas

Universidad de Chile

Santiago, Chile

1
Maria Vega

Academico Profesora Titular

Obstetricia y Ginecologia Campus Norte

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

1
Carmen Romero

Jefe Laboratorio Endocrinología y Biología Reproductiva

Obstetricia y Ginecología

HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE

Santiago, Chile

1
Juan Santibáñez

Professor of Research

Molecular Oncology

Institute for Medical Research

Belgrade, Serbia

1
Ariel Castro

Full Professor

Department of Biochemistry and Molecular Biology

UNIVERSIDAD DE CONCEPCION

concepciòn, Chile

1
Roxana Pincheira

Full Professor

Bioquímica y Biología Celular

Universidad de Concepcion

Concepción, Chile

1
LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
Juan Miquel

Full Professor

Gastroenterology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Rolando de la Cruz

Associate Professor

Faculty of Engineering and Sciences

Universidad Adolfo Ibáñez

Peñalolén, Santiago, Chile

1
Pablo Toro

Profesor Asociado

Psiquiatría

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Claudia Foerster

Associate Professor

Institute of Agri-food, Animal and Environmental Sciences

Universidad de O'Higgins

San Fernando, Chile

1
SANDRA CORTES

ASSOCIATED PROFESSOR

PUBLIC HEALTH

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
Alejandra Vives

DEPTO. SALUD PÚBLICA, UNIVESIDAD CATÓLICA DE CHILE

Santiago, Chile

1
daniel hevia

Investigador PhD

Inmunologia

Universidad de Chile

santiago, Chile

1
Carlos Puebla

Profesor Asistente

Universidad de O'Higgins

Rancagua, Chile

1
Steffen Härtel

Full Professor

Instituto de Ciencias Biomédicas

University of Chile

Santiago, Chile

1
Ramiro Zepeda

Academico

Farmacologia y neurociencia

universidad de Chile

santiago, Chile

1
Paola Llanos

Profesor Asistente

Instituto de Investigacion en Ciencias Biomédicas

FACULTAD DE ODONTOLOGIA. UNIVERSIDAD DE CHILE

Santiago, Chile

1
Maite Castro

Professor

Faculty of Sciences

UNIVERSIDAD AUSTRAL DE CHILE

Valdivia, Chile

1
Carlos Puebla

Assistant Professor

Universidad de O'Higgins

Santiago, Chile

1
Rodrigo Herrera

Group Leader (staff member)

Combinatorial NeuroImaging Core Facility

Leibniz Institute for Neurobiology

Magdeburg, Alemania

1
Patricio Baeza

adjunt profesor

PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

Valparaiso, Chile

1
Augusto Manubens

Director

Tecnical Support

BIOSONDA S.A.

Santiago, Chile

1
Gerald Zapata

Profesor Asociado

Química Inorgánica y Analítica

Universidad de Chile

Santiago, Chile

1
Felipe Court

Full Professor and Director

Center for Integrative Biology

Universidad Mayor

Huechuraba, Chile

1
Sebastián Illanes

professor, Director of Reproductive Biology Laboratory

Medicine

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

1
Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

1
Rodrigo Alzamora

ASSISTANT PROFESSOR

INSTITUTE OF BIOMEDICAL SCIENCES

UNIVERSIDAD DE CHILE

Santiago, Chile

1
José Jiménez

Postdoc

Investigación

Fundacion Ciencia y Vida

Santiago, Chile

1
Cesar Oyarce Diaz

Posdtoc

MMB

UMCG

Groningen, Holanda

1
JULIO TAPIA

Full Professor

Program of Cellular and Molecular Biology

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Franz Villarroel

Jefe Laboratorio - PI

Departamento de Investigación del Cáncer

Fundación Arturo López Pérez

Santiago, Chile

1
Miguel Allende

Director

Biología

FACULTAD DE CIENCIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

1
María Becker

Scientific Director, President

Research and Development

FUNDACIÓN CIENCIA Y TECNOLOGÍA PARA EL DESARROLLLO

Santiago, Chile

1
CESAR RAMIREZ

Assistant Professor

Institute for Biological and Medical Engineering

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Julio Cardenas

Associated Professor

Center for Integrative Biology

Universidad Mayor de Chile

Santiago, Chile

1
Álvaro Passi

PhD student

Research Department of Epidemiology & Public Health

University College London

London, Reino Unido

1
ARTURO FERREIRA

FULL PROFESSOR, CHAIR IMMUNOLOGY DISCIPLINARY PROGRAM

IMMUNOLOGY

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

1
Manuel Valenzuela

Académico Investigador

VRA

Universidad Central de Chile

santiago, Chile

1
Rodrigo Maldonado

Docente Investigador

Facultad de Medicina y Ciencia

Universidad San Sebastián

Valdivia, Chile

1
FRANCISCO NUALART

Full Professor and Scientific Director

Cellular Biology and Center for Advanced Microscopy CMA BIO-BIO

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

1
Fabián Jaña

Profesor Asistente

Departamento de Ciencias de la Salud

Universidad de Aysén

Coyhaique, Chile

1
Michelle Salazar

Asistente de Investigación

Fundación Ciencia y Tecnología para el Desarrollo (FUCITED)

Santiago, Chile

1
Maria González

Academico

FACULTAD DE MEDICINA - UNIVERSIDAD DE CHILE

Santiago, Chile

1
Ana Rojas

Asistente de Investigación

Universidad Autónoma de Chile

Santiago, Chile

1
Carlos Irarrazabal

Full Professor

Fisiología

Universidad de Los Andes

Santiago, Chile

1
Sergio González

FACULTAD DE MEDICINA. PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
RICARDO MORENO

Profesor Titular

Fisiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, FACULTAD DE CIENCIAS BIOLÓGICAS, DEPTO. DE FISIOLOGÍA

Santiago, Chile

1
Juan Reyes

PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO

Valparaiso, Chile

1
Sergio Uribe

Associated professor

Radiology

PONTIFICIA UNIVERSIDAD CATÓLICA

Santiago, Chile

1
Fabian Salazar

Postdoctoral Research Fellow

Biosciences

MRC Centre for Medical Mycology, University of Exeter

Exeter, Reino Unido

1
Vinicius Ramos Henriques

Associate Professor

Advanced Center for Chronic Diseases - ACCDiS

Univesidad de Chile

Santiago, Chile

1
Carolina Ribeiro

Assistant Professor

Immunology Program

UNIVERSIDAD DE CHILE - FACULTAD DE MEDICINA

Santiago, Chile

1
JENNY FIEDLER

LAB. NEUROPLASTICIDAD Y NEUROGENETICA. DEPTO BIOQUIMICA Y BIOLOGÍA MOLECULAR. FAC. CIENCIAS QUÍMICAS Y FARMACÉUTICAS. UNIVERSIDAD DE CHILE

Santiago, Chile

1
Jenny Blamey

Director Científico

Research and Development

FUNDACIÓN CIENTÍFICA Y CULTURAL BIOCIENCIA

Santiago, Chile

1
MONICA ACEVEDO

Titular Professor

Division of Cardiovascular Diseases

P. UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

1
Hernan Lara

Profesor Titular

Bioquimica y Biologia Molecular

U DE CHILE, FAC CIENCIAS QUIMICAS Y FARMACÉUTICAS

Santiago, Chile

1
Juan Prieto

Profesor Titular

Programa de Farmacología Molecular y Clínica

Universidad de Chile

Santiago, Chile

1
Marcelo Kogan

Academico

Quimica Farmacologica y Toxicologica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

1
Carlos Sepulveda

Investigador Postdoctoral

Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile.

Santiago, Chile

1
Ignacio Norambuena

Postdoctorado

Universidad de Chile

Santiago, Chile

1
Victor Aliaga

Postdoctorante

Universidad de O'Higgins

Santiago, Chile

1
Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

1
ALEJANDRO CORVALAN

Principal Investigator

Hematology and Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

1
Mauricio Henriquez

Profesor asistente

PROGRAMA DE FISIOLOGÍA Y BIOFíSICA

Universidad de Chile / Facultad de Medicina

Santiago, Chile

1
Arnaldo Marín

Profesor Adjunto

Basico Clinico de Oncologia

Universidad de Chile

Santiago, Chile

1
Sabrina Sepúlveda

Profesor Asistente

Medicina

Universidad Mayor de Chile

Santiago, Chile

1
Ricardo Huilcamán

Investigador

Universidad de Chile

Santiago, Chile

1
María Sánchez

Académica

Biología

Universidad de Santiago de Chile

Santiago, Chile

1
Paulina Villar

Tesista doctorado en bioquímica

Bioquímica

Universidad de Chile

Santiago, Chile

1
Luigi Devoto

PROFESOR TITULAR

INSTITUTO DE INVESTIGACIONES MATERNO INFANTIL,FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Edio Maldonado

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA

Santiago, Chile

1
Sergio Arancibia

Medical Science Liaison

Medical Affairs

Johnson & Johnson (Janssen Pharmaceutical)

Santiago, Chile

1
Sebastián Leiva

Lab Manager

Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

1
juan duaso

Academico

Universidad Vina del Mar

Viña del Mar, Chile

1
Johanna Acevedo

Profesor asociado investigador

Instituto de Ciencias e Innovación en Medicina (ICIM)

Universidad del Desarrollo

Santiago, Chile

1
Yedy Israel

Profesor Titular

Farmacologia Molecular y Clinica

UNIVERSIDAD DE CHILE, FACULTAD DE CS QUIMICAS Y FARMACÉUTICAS, LAB. FARMACOTERAPIA GÉNICA

Santiago, Chile

1
paula margozzini

Associate Professor

Public Health

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Rodrigo Morales

Postdoctoral researcher

Dept. of Medicine Solna (MedS)

Karolinska Institutet

Stockholm, Suecia

1
Sandra Espinoza

Coordinadora de campo clínico

Tecnología y Ciencias Farmacéuticas

Universidad de Chile

Santiago, Chile

1
Jaime Melendez

Prof. Asistente

Farmacia

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Francisco Fuentes

Profesor Asistente

Departamento de Microbiología

Universidad de Concepción

Concepción, Chile

1
Fernanda Sanhueza

Bioquímica

Hospital Base San José de Osorno

Osorno, Chile