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JORGE EMILIO JALIL MILAD

FULL PROFESSOR

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, ESCUELA DE MEDICINA

Santiago, Chile

REMODELADO CARDIOVASCULAR FISIOPATOLOGIA CARDIOVASCULAR VIA RHO A /RHO KINASA EN HIPERTENSION ARTERIAL E INSUFICIENCIA CARDIACA INSUFICIENCIA CARDIACA HIPERTENSION ARTERIAL SISTEMA RENINA ANGIOTENSINA ALDOSTERONA

MD, UNIVERSIDAD DE CHILE. Chile, 1980
MD, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1980

RESIDENT FELLOW INTERNAL MEDICINE DE MEDICINA Full Time

UNIVERSIDAD DE CHILE

MEDICINA

SANTIAGO, Chile

1981 - 1984
RESIDENT FELLOW IN CARDIOLOGY Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

MEDICINA

SANTIAGO, Chile

1984 - 1986
POSTDOCTORAL RESEARCH FELLOW Full Time

MICHAEL REESE HOSPITAL AFFILIATED TO THE UNIVERSITY OF CHICAGO

CHICAGO, Estados Unidos

1986 - 1989

FULL PROFESSOR Full Time

PUC, SCHOOL OF MEDICINE

SANTIAGO, Chile

2008 - A la fecha


Cantin C, Jalil JE, Bulnes JF, Novoa U, MacNab P, Godoy I, Córdova S, Gabrielli L, Ocaranza MP. Cantin C, Jalil JE, Bulnes JF, Novoa U, MacNab P, Godoy I, Córdova S, Gabrielli L, Ocaranza MP. Effect of Early Normotension with Olmesartan on Rho-kinase Activity in Hypertensive Patients. Curr Vasc Pharmacol. 2019 Jan 20. doi: 10.2174/157016111766619 Article ISI Epub ahead of print Curr Vasc Pharmacol (2019)
Elevated Systemic Inflammatory Burden and Cardiovascular Risk in Young Adults with Endodontic Apical Lesions Garrido M.; CÃ¡rdenas A.M.; Astorga J.; Quinlan F.; ValdÃ©s M.; Chaparro A.; Carvajal P.; Pussinen P.; HuamÃ¡n-Chipana P.; Jalil J.E.; HernÃ¡ndez M. Article ISI SCOPUS JOURNAL OF ENDODONTICS (2019)
Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension. Gonzalez L, Novoa U, Moya J, Gabrielli L, Jalil JE, García L, Chiong M, Lavandero S, Ocaranza MP. Article ISI Biochem Pharmacol. (2018)
Potential adverse cardiac remodelling in highly trained athletes: still unknown clinical significance. Gabrielli L, Sitges M, Chiong M, Jalil J, Ocaranza M, Llevaneras S, Herrera S, Fernandez R, Saavedra R, Yañez F, Vergara L, Diaz A, Lavandero S, Castro P. Article Eur J Sport Sci (2018)
Protection of the myocardium against ischemia/reperfusion injury by angiotensin-(1-9) through an AT(2)R and Akt-dependent mechanism. Mendoza-Torres E, Riquelme JA, Vielma A, Sagredo AR, Gabrielli L, Bravo-Sagua R, Jalil JE, Rothermel BA, Sanchez G, Ocaranza MP, Lavandero S. Article ISI Pharmacol Res. (2018)
Rho kinase activation in circulating leukocytes is related to hypertensive myocardial remodeling. Ocaranza MP, Fierro C, Jalil JE, Moya J, Gonzalez L, Molina C, Mancilla C. Rho kinase activation in circulating leukocytes is related to hypertensive myocardial remodeling. Clin Sci (Lond). 2018 Aug 30;132(16):1837-1853. Article ISI Clin Sci (Lond). (2018)
Does Good Aerobic Capacity Attenuate the Effects of Aging on Cardiovascular Risk Factors? Results from a Cross-Sectional Study in a Latino Population. Valentino G, Acevedo M, Orellana L, Bustamante MJ, Kramer V, Adasme M, Baraona F, Chamorro G, Jalil J, Navarrete C. Does Good Aerobic Capacity Attenuate the Effects of Aging on Cardiovascular Risk Factors? Results from a Cross-Sectional Study in a Latino Article SCOPUS Int J Endocrinol. 2017;2017:8351635. (2017)
Diuretics prevent Rho-kinase activation and expression of profibrotic/oxidative genes in the hypertensive aortic wall. Araos P, Mondaca D, Jalil JE, Yañez C, Novoa U, Mora I, Ocaranza MP. Article SCOPUS Ther Adv Cardiovasc Dis. (2016)
Mechanisms of favorable effects of Rho kinase inhibition on myocardial remodeling and systolic function after experimental myocardial infarction in the rat Mera C.; Godoy, I.; Ramirez R.; Moya, J; Ocaranza M.P.; Jalil J.E. Article SCOPUS Therapeutic Advances In Cardiovascular Disease (2016)
On Endogenous Angiotensin II Antagonism in Hypertension The Role of Dipeptidyl Peptidase III Ocaranza, María Paz; Jalil, Jorge E. Article ISI SCOPUS HYPERTENSION (2016)
Simultaneous Rho kinase inhibition in circulating leukocytes and in cardiovascular tissue in rats with high angiotensin converting enzyme levels Fierro C.; Novoa U.; González V.; Ocaranza M.P.; Jalil J.E. Article ISI SCOPUS INTERNATIONAL JOURNAL OF CARDIOLOGY (2016)
ACE2 and vasoactive peptides: novel players in cardiovascular/renal remodeling and hypertension. Mendoza-Torres E, Oyarzún A, Mondaca-Ruff D, Azocar A, Castro PF, Jalil JE, Chiong M, Lavandero S, Ocaranza MP. Article ISI Ther Adv Cardiovasc Dis. (2015)
Estrogens and myocardial chymase: new insights into pathological hypertrophy and remodeling. Jalil JE, Ocaranza MP. Article HYPERTENSION (2015)
Gaps and Resemblances in Current Heart Failure Guidelines: A Clinical Perspective. Bulnes JF, Jalil JE. Article Heart Fail Clin. (2015)
Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis. Ocaranza MP, Moya J, Barrientos V, Alzamora R, Hevia D, Morales C, Pinto M, Escudero N, García L, Novoa U, Ayala P, Díaz-Araya G, Godoy I, Chiong M, Lavandero S, Jalil JE, Michea L. Article ISI J Hypertens (2014)
Effects of Trimetazidine in Nonischemic Heart Failure: A Randomized Study Winter, José Luis; Castro Pablo F.,; Quintana, Juan Carlos; Altamirano, Rodrigo; Enriquez, Andres; Verdejo Hugo E.; Jalil, Jorge E.; Mellado, Rosemarie; Concepción, Roberto; Sepúlveda, Pablo; Rossel, Victor; Sepúlveda, Luis; Chiong, Mario; Garcia, Lorena; Lavandero, Sergio Article ISI JOURNAL OF CARDIAC FAILURE (2014)
Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system. Ocaranza MP, Michea L, Chiong M, Lagos CF, Lavandero S, Jalil JE. Article WOS Clin Sci (Lond) (2014)
Reply: dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure. Ocaranza MP, Michea L, Chiong M, Lavandero S, Jalil JE. Reply: dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure. J Hypertens. 2014 Aug;32(8):1719-21. doi: 10.1097/HJH.0000000000000247. PubMed PMID: 2499179 Article J Hypertens. (2014)
Rapid aspirin desensitization in patients with a history of aspirin hypersensitivity requiring coronary angioplasty. Report of four cases Veas, N; Martinez, G; Jalil J.; Martínez A; Castro P. Article ISI REVISTA MEDICA DE CHILE (2013)
[Cardiovascular risk factors in a group of health care workers]. [Agregación de factores de riesgo cardiovascular y conciencia de enfermedad en trabajadores de un hospital universitario.] Kramer V.; Adasme M.; Bustamante M.J.; Jalil J.; Navarrete C.; Acevedo M. Article SCOPUS Rev Med Chile (2012)
Agregación de factores de riesgo cardiovascular y conciencia de enfermedad en trabajadores de un hospital universitario Kramer, Verónica; Adasme, Marcela; Bustamante, M. José; Jalil, Jorge; Navarrete, Carlos; Acevedo, Monica Article SCIELO REVISTA MEDICA DE CHILE (2012)
Cardiovascular risk factors in a group of health care workers Kramer V.; Adasme M.; Bustamante, MJ; Jalil J.; Navarrete C.; Acevedo M. Article ISI REVISTA MEDICA DE CHILE (2012)
Cardiovascular risk factors in a group of health care workers Agregación de factores de riesgo cardiovascular y conciencia de enfermedad en trabajadores de un hospital universitario Kramer V.; Adasme M.; Jose Bustamante, M.; Jalil J.; Acevedo M.; Navarrete C. Article SCOPUS Revista Medica de Chile (2012)
Mayores niveles de ECA y Angiotensina II determinados genéticamente, se asocian a menor actividad del eje ECA2/angiotensina-(1-9) y mayor remodelamiento de la pared aórtica de ratas hipertensas Moya, Jackeline; Novoa, Ulises; Escudero, Nicolas; Godoy, Ivan; Chiong, Mario; Lavandero, Sergio; Jalil, Jorge; Ocaranza, Maria Paz Article SCIELO Revista chilena de cardiología (2012)
Protective role of the ACE2/Ang-(19) axis in cardiovascular remodeling Ocaranza M.P.; Jalil J.E. Article SCOPUS International Journal of Hypertension (2012)
Hidroclorotiazida y espironolactona reducen la hipertrofia de la pared aórtica en la hipertensión arterial experimental Mondaca, David; Araos, Patricio; Yañez, Cristian; Novoa, Ulises; Ocaranza, Maria Paz; Jalil, Jorge Article SCIELO Revista chilena de cardiología (2011)
Markedly increased Rho-kinase activity in circulating leukocytes in patients with chronic heart failure Ocaranza, MP; Gabrielli, L; Mora I; Garcia, L.; Mcnab P.; Godoy, I.; Braun, S; Cordova S; Castro P. ; Novoa U.; Chiong M.; Lavandero S.; JALIL, JE Article ISI SCOPUS American Heart Journal (2011)
Mayor actividad de rho kinasa en leucocitos circulantes se asocia a estrés oxidativo y rigidez arterial en hipertensos diabéticos Gabrielli, Luigi; Berkovitz, Alejandro; Mora, Italo; Novoa, Ulises; Godoy, Ivan; MacNab, Paul; Córdova, Samuel; Padilla, Ivonne; Rigotti, Paola; Garcia, Lorena; Lavandero, Sergio; Ocaranza, Maria Paz; Jalil, Jorge Article SCIELO Revista chilena de cardiología (2011)
Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1-9) axis in experimental hypertension Ocaranza, MP; rivera, p; Novoa U.; Pinto, M; Gonzalez L.; Chiong M.; Lavandero S.; JALIL, JE Article ISI SCOPUS Journal of Hypertension (2011)
Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro Ocaranza, MP; Lavandero S.; JALIL, JE; Moya, J; Pinto, M; Novoa U.; Apablaza F.; Gonzalez L.; Hernandez C.; Varas, M; Lopez R.; Godoy, I.; Verdejo H.; Chiong M. Article ISI SCOPUS Journal of Hypertension (2010)
Efectividad del uso combinado de un inhibidor de Rho Kinasa y de un antagonista del receptor de angiotensina II en la prevención de hipertrofia ventricular en ratas hipertensas Novoa, Ulises; Ocaranza, Maria Paz; Mora, Italo; Jalil, Jorge Article SCIELO Revista chilena de cardiología (2010)
Heart energy metabolism and its role in the treatment of heart failure Metabolismo energético del corazón y sus proyecciones en el tratamiento de la insuficiencia cardíaca Castro P. ; Gabrielli, L; Verdejo H.; greig d.; Llevaneras, S; Hernandez C.; Godoy, I.; Jalil J.E.; Quintana J.C.; Orellana P.; Mellado R.; Concepcion, R; Sepulveda, L; Vukasovic J.L.; Garcia, L.; Pizarro M.; Pivet, D; Carrillo, C.; Tapia, F; Navarro M.; Troncoso R.; Chiong M.; Lavandero S.; Baraona F. Article SCOPUS Revista Medica de Chile (2010)
Increased levels of oxidative stress, subclinical inflammation, and myocardial fibrosis markers in primary aldosteronism patients Stehr C.B.; Carvajal, C. A.; Mosso L.; Becerra E.; Fardella C.E.; Mellado R.; Ocaranza M.P.; Jalil J.; Solis, M; Garcia, L.; Lavandero S. Article ISI SCOPUS Journal of Hypertension (2010)
La sobreexpresión del gen de enzima convertidora de angiotensina homóloga (ECA2) revierte la hipertensión arterial y el remodelado cardíaco experimental Ramos, Elizabeth; Herrera, Alejandro; Moya, Jackeline; Apablaza, Felipe; Godoy, Ivan; Jalil, Jorge; Lavandero, Sergio; Chiong, Mario; Ocaranza, Maria Paz Article SCIELO Revista chilena de cardiología (2010)
La sobrexpresión génica vascular de NADPH oxidasa en la hipertensión arterial experimental se reduce solamente con inhibición directa de Rho kinasa Jalil, Jorge; Novoa, Ulises; Mora, Italo; Ocaranza, Maria Paz Article SCIELO Revista chilena de cardiología (2010)
Menores niveles tisulares de la enzima convertidora de angiotensina I homologa (ECA-2) y angiotensina-(1-9) están asociados a mayor remodelamiento de la pared aórtica de ratas hipertensas Ocaranza, Maria Paz; Moya, Jackeline; Pinto, Melissa; Escudero, Nicolas; Valenzuela, Francisco; Varas, Manuel; Godoy, Ivan; Chiong, Mario; Lavandero, Sergio; Jalil, Jorge Article SCIELO Revista chilena de cardiología (2010)
Cardiotrofina-1 circulante puede diferenciar la hipertrofia ventricular fisiológica del atleta de la hipertrofia patológica del paciente hipertenso Gabrielli, Luigi; Yáñez, Fernando; Ocaranza, Maria Paz; Godoy, Ivan; Castro, Pablo; Greig, Douglas; HERNÁNDEZ, CLAUDIA; LLEVANERAS, SILVANA; Jalil, Jorge Article SCIELO Revista chilena de cardiología (2009)
La vía de señalización Rho A/ Rho Kinasa se encuentra activada en el miocardio en ratas con fibrosis cardíaca inducida por isoprotenerol Vargas, Mónica; Rivera, Paulina; Ocaranza, Maria Paz; Jalil, Jorge Article SCIELO Revista chilena de cardiología (2009)
Early expression of monocyte chemoattractant protein-1 correlates with the onset of isoproterenol-induced cardiac fibrosis in rats with distinct angiotensin-converting enzyme polymorphism Soto, MC; Valenzuela R.; Saldaña A.; Ocaranza, MP; JALIL, JE; Vio, C; Lijnen, P; Ordenes, GE; Sanchez, RV; Lavandero S.; Diaz-Araya, G Article ISI SCOPUS JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (2008)
Interacción entre los polimorfismos del receptor ß1 y ß2 adrenérgico como predictor de riesgo de insuficiencia cardiaca crónica Moraga, Francisco; Troncoso, Rodrigo; Mellado, Rosemarie; Diaz-Araya, Guillermo; Vukasovic, José Luis; Greig, Douglas; Pérez, Osvaldo; Garcia, Lorena; Roldán, Juan; Ocaranza, Maria Paz; Jalil, Jorge; Chiong, Mario; Castro, Pablo Article SCIELO REVISTA MEDICA DE CHILE (2008)
Interactions between beta(1) and beta(2) adrenergic receptor polymorphisms as risk factors for chronic heart failure Moraga, F; Troncoso R.; Mellado R.; Diaz-Araya, G; Vukasovic, JL; greig d.; Perez, O; Garcia, L.; Roldan, J; Ocaranza, MP; Jalil J.; Chiong M.; Castro P. Article ISI REVISTA MEDICA DE CHILE (2008)
Interactions between ß 1 and ß 2 adrenergic receptor polymorphisms as risk factors for chronic heart failure Interacción entre los polimorfismos del receptor ß 1 y ß 2 adrenérgico como predictor de riesgo de insuficiencia cardiaca crónica Moraga, F; Troncoso R.; Mellado R.; Diaz-Araya, G; Garcia, L.; Roldan, J; Chiong M.; Vukasovic J.L.; greig d.; Perez, O; Ocaranza M.P.; Jalil J.; Castro P. Article REVISTA MEDICA DE CHILE (2008)
MAYOR EXPRESION DE LA ENZIMA CONVERTIDORA DE ANGIOTENSINA I HOMOLOGA (ECA2) EN LA PARED ARTERIAL DE RATAS CON NIVELES GENETICAMENTE ELEVADOS DE ANGIOTENSINA II: EFECTOS DECANDESARTAN Y FASUDIL Ocaranza, Maria; Rivera, Paulina; Jalil, Jorge Article REVISTA CHILENA DE CARDIOLOGIA (2008)
MENOR EXPRESION DE LA ENZIMA CONVERTIDORA DE ANGIOTENSINA I HOMOLOGA (ECA2) SE ASOCIA A MAYOR REMODELAMIENTO DE LA PARED AORTICA DE RATAS CON NIVELES GENETICAMENTE ELEVADOS DE ANGIOTENSINA II Ocaranza, Maria; Moya, Jackeline; Valenzuela, Francisco; Varas, Manuel; Jalil, Jorge Article REVISTA CHILENA DE CARDIOLOGIA (2008)
Osmotically-induced genes are controlled by the transcription factor TonEBP in cultured cardiomyocytes Navarro P.; Chiong M.; Volkwein, K; Moraga, F; Ocaranza, MP; JALIL, JE; Lim, SW; Kim, JA; Kwon, HM; Lavandero S. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
FASUDIL PREVIENE LA SOBREXPRESION DE GENES PROCOAGULANTES, PROINFLAMATORIOS Y PROFIBROTICOS EN LA PARED ARTERIAL DE RATAS HIPERTENSAS Rivera, Paulina; Tichauer, Juan; Lavandero, Sergio; Ocaranza, Maria; Jalil, Jorge Article REVISTA CHILENA DE CARDIOLOGIA (2007)
Rho kinase activation and gene expression related to vascular remodeling in normotensive rats with high angiotensin I-converting enzyme levels rivera, p; Ocaranza, MP; Lavandero S.; JALIL, JE Article ISI HYPERTENSION (2007)
Effect of hypertension on angiotensin-(1-7) levels in rats with different angiotensin-I converting enzyme polymorphism Ocaranza, MP; Palomera, C; Román M.; Bargetto, J; Lavandero S.; JALIL, JE Article ISI SCOPUS LIFE SCIENCES (2006)
Enalapril attenuates downregulation of angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat Ocaranza, MP; Godoy, I.; JALIL, JE; Varas, M; Collantes, P; Pinto, M; Román M.; Ramírez C.; Copaja M; Diaz-Araya, G; Castro P. ; Lavandero S. Article ISI SCOPUS HYPERTENSION (2006)
Usefulness of sublingual isosorbide to assess the reversibility of pulmonary hypertension in cardiac transplant candidates Baraona F.; Castro P. ; Perez, O; Moran S.; Zalaquett R.; Irarrazabal, MJ; Jalil J. Article ISI REVISTA MEDICA DE CHILE (2006)
DISMINUCION DE LA ACTIVIDAD DE LA ECA-2 (ENZIMA CONVERTIDORA DE ANGIOTENSINA I HOMOLOGA) EN LA DIFUNCION VENTRICULAR IZQUIERDA POST INFARTO AL MIOCARDIO EN LA RATA Ocaranza, Maria; Godoy, Ivan; Ramirez, Cristian; Jalil, Jorge Article REVISTA CHILENA DE CARDIOLOGIA (2005)
Increased aortic NADPH oxidase activity in rats with genetically high angiotensin-converting enzyme levels JALIL, JE; Pérez, A.; Ocaranza, MP; Bargetto, J; Galaz, A.; Lavandero S. Article ISI SCOPUS HYPERTENSION (2005)
MAYOR ACTIVIDAD DE NADPH OXIDASA VASCULAR EN RATAS CON NIVELES ELEVADOS DE ECA Pérez, Alfonso; Ocaranza, Maria; Jalil, Jorge Article REVISTA CHILENA DE CARDIOLOGIA (2005)
Perindopril regulates ?-agonist-induced cardiac apoptosis Galvez A.S.; Fiedler J.L.; Ocaranza M.P.; Lavandero S.; Jalil J.E.; Diaz-Araya, G Article SCOPUS JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2005)
Effects of tilt test and beta-adrenergic stimulation on the QT interval in normal children and pediatric patients with unexplained syncope Efectos de la prueba de la mesa basculante y de la estimulación betaadrenérgica sobre el intervalo QT en niños sanos y en pacientes pediátricos con síncope de etiología no precisada Arnaiz P.; Dumas, E; Heusser, F; González R.; Jalil J. Article SCOPUS REVISTA ESPANOLA DE CARDIOLOGIA (2004)
Neutral endopeptidase and angiotensin I converting enzyme insertion/deletion gene polymorphism in humans JALIL, JE; Ocaranza, MP; Oliveri, C; Cordova S; Godoy, I.; Chamorro, G; Braun, S; Fardella, C.; Michel, JB; Lavandero S. Article ISI SCOPUS JOURNAL OF HUMAN HYPERTENSION (2004)
Administration of growth hormone to patients with advanced cardiac heart failure: effects upon left ventricular function, exercise capacity, and neurohormonal status Acevedo M.; Corbalan, R; Chamorro, G; Jalil J.; Nazzal C.; Campusano, C; Castro P. Article ISI SCOPUS INTERNATIONAL JOURNAL OF CARDIOLOGY (2003)
Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-1-converting enzyme deletion/deletion genotype JALIL, JE; Palomera, C; Ocaranza, MP; GODOY, L.; Román M.; Chiong M.; Lavandero S. Article ISI SCOPUS AMERICAN JOURNAL OF CARDIOLOGY (2003)
Long-term automated peritoneal dialysis in patients with refractory congestive heart failure. Ortiz A.M.; Acosta P.A.; Corbalan, R; Jalil J.E. Article Advances in peritoneal dialysis. Conference on Peritoneal Dialysis. (2003)
Relation between oxidative stress, catecholamines, and impaired chronotropic response to exercise in patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy Castro, PF; greig d.; Perez, O; Moraga, F; Chiong M.; Diaz-Araya, G; Padilla I.; Nazzal C.; JALIL, JE; Vukasovic, JL; Moreno, M.; Corbalan, R; Lavandero S. Article ISI SCOPUS AMERICAN JOURNAL OF CARDIOLOGY (2003)
A 36 years experience with implantable pacemakers Dubernet, J; Chamorro, G; Gonzalez, J; Fajuri A.,; Jalil J.; Casanegra P.; Maturana G.; Moran S.; Zalaquett R.; Irarrazaval, MJ; Urzúa J.; Rodriguez JA.; Braun, S; Corbalan, R; González R.; Marchant, E Article ISI REVISTA MEDICA DE CHILE (2002)
Angiotensin I-converting enzyme gene polymorphism influences chronic hypertensive response in the rat Goldblatt model Ocaranza, MP; Piddo, AM; Faundez, P; Lavandero S.; JALIL, JE Article ISI SCOPUS JOURNAL OF HYPERTENSION (2002)
Angiotensin I-converting enzyme insertion/deletion polymorphism and adrenergic response to exercise in hypertensive patients Jalil J.E.; Cordova S; Ocaranza M.P.; Schumacher, E; Braun, S; Chamorro, G; Fardella, C.; Lavandero S. Article Medical Science Monitor (2002)
Persistence of oxidative stress after heart tranplantation: A comparative study of patients with heart transplant versus chronic stable heart failure Perez, O; Castro P. ; Diaz-Araya, G; Nettle, D; Moraga, F; Chiong M.; Jalil J.; Zalaquett R.; Moran S.; Becker P.; Corbalan, R; Lavandero S. Article SCOPUS REVISTA ESPANOLA DE CARDIOLOGIA (2002)
Persistence of oxidative stress after heart transplantation: A comparative study of patients with heart transplant versus chronic stable heart failure Perez, O; Castro P. ; Diaz-Araya, G; Nettle, D; Moraga, F; Chiong M.; Jalil J.; Zalaquett R.; Moran S.; Becker P.; Corbalan, R; Lavandero S. Article ISI REVISTA ESPANOLA DE CARDIOLOGIA (2002)
Angiotensin I-converting enzyme modulates neutral endopeptidase activity in the rat Oliveri, C; Ocaranza, MP; Campos X; Lavandero S.; JALIL, JE Article ISI HYPERTENSION (2001)
Early prevention of experimental left ventricular hypertrophy in experimental hypertension and angiotensin II levels Galvez A.; Ocaranza, MP; Lavandero S.; JALIL, JE Article ISI REVISTA ESPANOLA DE CARDIOLOGIA (2001)
Genetic study of patients with dexamethasone-suppressible aldosteronism without the chimeric CYP11B1/CYP11B2 gene Fardella, CE; Pinto, M; Mosso L.; Gomez-Sanchez, C; Jalil J.; Montero J. Article ISI SCOPUS JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2001)
Hyperuricemia as a marker for anaerobic threshold in chronic cardiac failure Martínez A; Perez, P.; Ossa C.; Corbalan, R; Jalil J.; Acevedo, PCG Article ISI REVISTA MEDICA DE CHILE (2001)
Selective training of respiratory muscles in patients with chronic heart failure Martínez A; Lisboa C.; Jalil J.; Muñoz, V; Díaz O.; Casanegra P.; Corbalan, R; Vasquez, AM; Leiva A. Article ISI REVISTA MEDICA DE CHILE (2001)
D/d polymorphism of the ace gene might be a risk factor for in-stent restenosis El genotipo D/D del gen de la enzima conversiva de la angiotensina como factor de riesgo de reestenosis post-stent coronario Guarda E.; Fajuri A.,; Marchant, E; Martínez A; Jalil J.; Illanes, G; Vecchiola, A; Lazen, R; Flores A.; Barra V; Irarrazabal, S.; Ilabaca, F. Article REVISTA ESPANOLA DE CARDIOLOGIA (1999)
Effects of antihypertensive treatment on cardiac IGF-1 during prevention of ventricular hypertrophy in the rat Jalil J.E.; Ebensperger, R; Meléndez J.; Acevedo, E; Sapag-Hagar, M; Gonzalez-Jara, F; Galvez A.; Perez-Montes V.; Lavandero S. Article LIFE SCIENCES (1999)
Enalapril restores depressed circulating insulin-like growth factor 1 in patients with chronic heart failure Corbalan, R; Acevedo M.; Godoy, I.; Jalil J.; Campusano, C; Klassen, J Article JOURNAL OF CARDIAC FAILURE (1998)
Selective increase in cardiac IGF-1 in a rat model of ventricular hypertrophy Ebensperger, R; Acevedo, E; Meléndez J.; Sapag-Hagar, M; Lavandero S.; Corbalan, R; Acevedo M.; Jalil J.E. Article BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (1998)
Cyclic AMP dependent protein kinase and mechanical heart function in ventricular hypertrophy induced by pressure overload or secondary to myocardial infarction Piddo A.M.; Sanchez M.I.; Sapag-Hagar, M; Corbalan, R; Foncea, R; Ebensperger, R; Godoy, I.; Meléndez J.; Jalil J.E.; Lavandero S. Article JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (1996)
Regression of left ventricular hypertrophy in experimental renovascular hypertension: Diastolic dysfunction depends more on myocardial collagen than it does on myocardial mass Dussaillant G.R.; GONZALEZ, H; Cespedes, C; Jalil J.E. Article JOURNAL OF HYPERTENSION (1996)
Valor pronóstico de la monitoría ambulatoria de presión arterial en pacientes hipertensos: Observaciones en la literatura Mc-Nab M, Paul; Jalil, Jorge E. Article REVISTA MEDICA DE CHILE


Angiotensin-(1-9) Decreases Hypertension and Vascular Damage by Inhibiting Rhoa/rock Activity in Doca Hypertensive Rats Ocaranza, MP; Villegas, B; Moya, J; Barrientos, V; Novoa U.; Perez, O; Walkowiak, S; Chiong M.; Lavandero S.; Michea, L.; Jalil J. Abstract ISI HYPERTENSION (2013)
NON TRADITIONAL RISK FACTORS AND MORTALITY: DO THEY ADD INFORMATION BEYOND TRADITIONAL RISK FACTORS? Kramer V.; Yañez F.; Godoy, I.; Jalil J.; Corbalan, R; Navarrete C.; Acevedo M. Abstract JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2012)
Angiotensin-(1-9) Prevents Cardiomyocyte Hypertrophy Through Calcium Influx Dependent Pathway Ocaranza, MP; Hechenleitner, J; Gonzalez L.; Chiong M.; Jalil J.; Lavandero S. Abstract HYPERTENSION (2011)
Angiotensin-(1-9) Prevents the Cardiovascular Pathological Remodeling Induced by Angiotensin II In Vivo Ocaranza, MP; Lagos T.; Moya, J; Morales C. ; Gonzalez L.; Novoa U.; Chiong M.; Lavandero S.; Jalil J. Abstract HYPERTENSION (2011)
CARDIOVASCULAR RISK FACTORS AMONG A UNIVERSITY HOSPITAL HEALTH WORKERS POPULATION IN SANTIAGO, CHILE: HIGH BURDEN AND LOW AWARENESS Acevedo, MA; Kramer V.; Bustamante, MJ; Adasme M.; Jalil J. Abstract JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2011)
INCREASED RHO KINASE ACTIVITY AND OXIDATIVE STRESS LEVELS IN DIABETIC HYPERTENSIVE PATIENTS Gabrielli, L; Jalil J.; Ocaranza, MP; Novoa U.; Mora I; Godoy, I. Abstract JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2011)
Atorvastatin inhibits the Rho A/Rho kinase pathway and, reduces blood pressure and the expression of vascular remodeling genes in rats with genetically high levels of angiotensin II rivera, p; Ocaranza M.; Jalil J. Abstract CIRCULATION (2008)
Cardiotrophin-I plasma levels are increased in hypertensive patients with cardiac hypertrophy and diastolic dysfunction Gabrielli, L; Ocaranza M.; Godoy, I.; Llevaneras, S; Jalil J. Abstract JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)
Increased angiotensin converting enzyme 2 activity (ACE2) during prevention of left ventricular hypertrophy with an ACE inhibitor Ocaranza, MP; Ramírez C.; Jalil J. Abstract JOURNAL OF HYPERTENSION (2004)
The Arg389Arg adrenergic receptor variant interacts with the Arg16Arg and Gly27Gly beta 2 adrenergic receptor variants decreasing the risk for chronic heart failure Castro P. ; greig d.; Moraga, F; Chiong M.; Diaz-Araya, G; Vukasovic, JL; Jalil J.; Lavandero S. Abstract EUROPEAN HEART JOURNAL (2004)
beta(2)-adrenergic receptor polymorphisms are not associated with heart failure Lavandero S.; Moraga, F; Mario, C; Diaz-Araya, G; Vukasovic, JL; Pablo C.; Perez, O; Moreno, M.; Ocaranza, MP; Jalil J.; Ivonne, P; Nazal, C; Corbalan, R Abstract FASEB JOURNAL (2002)
Neutral endopeptidase and angiotensin I converting enzyme insertion/deletion gene polymorphism in normotensive and hypertensive subjects Jalil J.; Oliveri, C; Ocaranza, MP; Godoy, I.; Cordova S; Chamorro, G; Michel, JB; Lavandero S. Abstract EUROPEAN HEART JOURNAL (2002)
A clinical indication for natriuretic peptide CDD/ANP-95-126 in patients with heart and renal failure. Downey P.; Rosas, M; Jalil, R; Espinoza, ME; Morales E. ; Galleguillos, CG; Catalan, L; Jalil J.; Castro P. ; Larrain, G; Dohler, KD Abstract HYPERTENSION (2001)
Comparison of oxidative stress status between heart transplant and advanced chronic heart failure patients Castro P. ; Perez, O; Nettle, D; Lavanderos, S; Diaz-Araya, G; Corbalan, R; Nazzal C.; Jalil J.; Zalaquett R. Abstract EUROPEAN HEART JOURNAL (2001)
Myocardial angiotensin II generation and the angiotensin I - converting enzyme gene polymorphism in the rat Jalil J.; Ocaranza, MP; Piddo, AM; Faundez, P; Lavandero S. Abstract HYPERTENSION (2001)


Estrogens and Myocardial Chymase New Insights Into Pathological Hypertrophy and Remodeling JALIL, JE; Ocaranza, MP EditorialMaterial ISI SCOPUS Hypertension (2015)
Combined rho kinase and renin-angiotensin system inhibition: a new therapeutic perspective for renal and cardiovascular remodeling JALIL, JE; Jalil, R; Ocaranza, MP EditorialMaterial ISI SCOPUS Hypertension Research (2010)
Large Left Segmental Pulmonary Artery Pseudoaneurysm After Right Heart Catheterization Successful Percutaneous Closure Combined With Balloon Mitral Valvotomy Martínez A; Martinez, G; Heusser, F; Lindefjeld, D; Jalil J. EditorialMaterial ISI SCOPUS CIRCULATION (2010)
Mitogen-Activated Protein Kinases as Biomarkers of Hypertension or Cardiac Pressure Overload Ocaranza, MP; JALIL, JE EditorialMaterial ISI SCOPUS Hypertension (2010)
Blood pressure reduction, potassium channels, and the endothelium - Insights from L-serine JALIL, JE EditorialMaterial ISI HYPERTENSION (2008)
Effects of tilt test and beta-adrenergic stimulation on the QT interval in normal children and pediatric patients with unexplained syncope Arnaiz P.; Dumas, E; Heusser, F; González R.; Jalil J. EditorialMaterial REVISTA ESPANOLA DE CARDIOLOGIA (2004)


ACE2 and vasoactive peptides: Novel players in cardiovascular/renal remodeling and hypertension Mendoza-Torres, E; Oyarzun A.; Mondaca-Ruff, D.; Azocar, A.; Castro P.F.; Jalil J.E.; Chiong M.; Lavandero S.; Ocaranza M.P. Review SCOPUS Therapeutic Advances In Cardiovascular Disease (2015)
Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system Ocaranza, Maria Paz; Michea, Luis; Chiong, Mario; Lagos, Carlos F; Lavandero, Sergio; Jalil, Jorge E. Review ISI SCOPUS CLINICAL SCIENCE (2014)
Exercise and cardiac rehabilitation in secondary cardiovascular prevention Acevedo M.; Kramer V.; Bustamante, MJ; Yañez F.; Guidi, D.; Corbalan, R; Godoy, I.; Vergara, I; Jalil J.; Fernandez, M. Review REVISTA MEDICA DE CHILE (2013)
Rehabilitación cardiovascular y ejercicio en prevención secundaria Acevedo, Monica; Kramer, Verónica; Bustamante, María José; Yáñez, Fernando; Guidi, Dominique; Corbalán Ramón; Godoy, Ivan; Vergara, Ismael; Jalil, Jorge; Fernández, Marcelo Review SCIELO SCOPUS REVISTA MEDICA DE CHILE (2013)
Metabolismo energético del corazón y sus proyecciones en el tratamiento de la insuficiencia cardíaca Castro, Pablo; Gabrielli, Luigi; Verdejo, Hugo; Greig, Douglas; Mellado, Rosemarie; Concepción, Roberto; Sepúlveda, Luis; Vukasovic, José Luis; Garcia, Lorena; Pizarro, Marcela; PIVET, DEISY; Carrillo, Constanza; TAPIA, FABIOLA; Navarro, Mario; Troncoso, Rodrigo; Baraona, Fernando; LLEVANERAS, SILVANA; HERNÁNDEZ, CLAUDIA; Godoy, Ivan; Jalil, Jorge E.; Quintana, Juan Carlos; Orellana, Pilar; Chiong, Mario; Lavandero, Sergio Review SCIELO REVISTA MEDICA DE CHILE (2010)
Cardiac hypertrophy: Molecular and cellular events Carreño JE; Apablaza F.; Ocaranza, MP; JALIL, JE Review ISI REVISTA ESPANOLA DE CARDIOLOGIA (2006)
Prognostic value of ambulatory blood pressure monitoring in hypertensive patients. A review [Valor pronóstico de la monitoría ambulatoria de presión arterial en pacientes hipertensos: Observaciones en la literatura] Mc-Nab M P.; Jalil J.E. Review SCOPUS REVISTA MEDICA DE CHILE (2005)
Prognostic value of ambulatory blood pressure monitoring in hypertensive patients. A review Valor pronóstico de la monitoría ambulatoria de presión arterial en pacientes hipertensos: Observaciones en la literatura Mc-Nab M P.; Jalil J.E. Review REVISTA MEDICA DE CHILE (2005)
Rho/Rho kinase signal transduction pathway in cardiovascular disease and cardiovascular remodeling Jalil J.; Lavandero S.; Chiong M.; Ocaranza, MP Review ISI SCOPUS REVISTA ESPANOLA DE CARDIOLOGIA (2005)

108

JORGE JALIL

FULL PROFESSOR

ENFS CARDIOVASCULARES

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, ESCUELA DE MEDICINA

Santiago, Chile

SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

Maria Ocaranza

Asociate Professor

Cardiovascular Diseases Division

Pontificia Universidad Catolica de Chile

Santiago, Chile

Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

Ramon Corbalan

Director

Division of Cardiovascular Diseases

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

MONICA ACEVEDO

Titular Professor

Division of Cardiovascular Diseases

P. UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Lorena Garcia

Assistant Professor

Bioquimica y Biologia Molecular

UNIVERSIDAD DE CHILE

Santiago, Chile

Samuel Cordova

ESCUELA DE MEDICINA, PONTIFICA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Douglas Greig

Médico Jefe

Cardiología

P. Universidad Católica de Chile

Santiago, Chile

Pablo Castro

JEFE DIVISION

DIVISION ENFERMEDADES CARDIOVASCULARES

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

Rodrigo Troncoso

Assistant professor

Universidad de Chile, Instituto de Nutrición y Tecnología de los Alimentos

Santiago de Chile, Chile

Rosemarie Mellado

Jefe de carrera / Académica

Farmacia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Carlos Fardella

Profesor Titular

Endocrinología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Rodrigo Troncoso

Associate Professor

Instituto de Nutrición y Tecnología de los Alimentos

Santiago, Chile

Roberto Ebensperger

Associate Professor

Pharmacy

Pontificia Universidad Católica de Chile

Santiago, Chile

Luigi Gabrielli

Profesor Asistente

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile

MANUEL VARAS

Research Professor

UNIVERSIDAD SAN SEBASTIÁN

Santiago, Chile

Hugo Verdejo

Profesor Asociado

División de Enferemedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

Lorena Mosso

profesor titular

endocrinologia

Pontificia Universidad Catolica de Chile

santiago, Chile

Carlos Vio

Profesor

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Juan Carlos Quintana

Médico nuclear

Radiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Carolina Nazzal

Profesor Asociado

Instituto de Salud Poblacional

Universidad de Chile

Santiago, Chile

Leticia Gonzalez

Profesional Apoyo a la Investigacion

Pontificia Universidad Católica de Chile

Santiago, Chile

Luis Michea

PROFESOR ASOCIADO

PROGRAMA FISIOLOGIA Y BIOFISICA

UNIVERSIDAD DE CHILE

Santiago, Chile

Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

Cristian Carvajal

Associate Professor

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

JENNY FIEDLER

LAB. NEUROPLASTICIDAD Y NEUROGENETICA. DEPTO BIOQUIMICA Y BIOLOGÍA MOLECULAR. FAC. CIENCIAS QUÍMICAS Y FARMACÉUTICAS. UNIVERSIDAD DE CHILE

Santiago, Chile

Dante Lindefjeld

Staff, Assistant Professor

Cardiology

Clinical Hospital of the Pontificia Universidad Católica de Chile

Santiago, Chile

Pablo Sepúlveda

Cardiólogo Intervencionista

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

Pedro Pérez

Profesor Asociado

Medicina Interna

Pontificia Universidad Católica de Chile

Santiago, Chile

Patricio Araos

Profesor Asistente

Fisiología

Universidad Autónoma de Chile

Santiago, Chile

Juan Ossa

Profesor asistente

Pediatria y Cirugia Oriente

Universidad De Chile, Hospital Luis Calvo Mackenna

Santiago, Chile

Rodrigo Valenzuela

Postdoctorado

Oftalmología

Universidad de Chile

Santiago, Chile

Carlos Mauricio Garrido

Profesor Asistente

Odontología Conservadora

UNIVERSIDAD DE CHILE, FACULTAD DE ODONTOLOGÍA

Santiago, Chile

Orlando Diaz

Profesor Asociado

Enfermedades Respiratorias

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Patricio Downey

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE DEPARTAMENTO DE NEFROLOGIA

SANTIAGO, Chile

Macarena Valdes

Académica

Escuela de Salud Pública

Universidad de Chile

Santiago, Chile

Gonzalo Martínez

Director

División de Enfermedades Cardiovasculares

Hospital Clínico Universidad Católica

Santiago, Chile

Anita Gálvez

Profesor Asistente

Biomédico

Universidad de Antofagasta

Antofagasta, Chile

JORGE EMILIO JALIL MILAD

Líneas de Investigación

Educación

MD, UNIVERSIDAD DE CHILE. Chile, 1980

MD, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1980

Experiencia Académica

RESIDENT FELLOW INTERNAL MEDICINE DE MEDICINA Full Time

RESIDENT FELLOW IN CARDIOLOGY Full Time

POSTDOCTORAL RESEARCH FELLOW Full Time

Experiencia Profesional

FULL PROFESSOR Full Time

Article (77)

Abstract (15)

EditorialMaterial (6)

Review (9)