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Juan Carlos Roa Strauch

Chair

Pontificia Universidad Catolica de Chile

santiago, Chile

Biobank national network in Chile; Translational research in digestive tumor, with special emphasys in gallbladder cancer; Research on HPV and its role in cervix preneoplastic and neoplastic lesions.

Medical Doctor, UNIVERSIDAD DE LA FRONTERA. Chile, 1991
Oncologia molecular, Centro de estudios sanitarios de Europa. España, 2012
Especialista en Anatomia patologica, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1995
Fellowship in molecular biology, LOUISIANA STATE UNIVERSITY. Estados Unidos, 1999

Assistant Professor Part Time

UNIVERSIDAD DE LA FRONTERA

Medicine

Temuco, Chile

1995 - 2004
Associate Professor Part Time

UNIVERSIDAD DE LA FRONTERA

Medicine

Temuco, Chile

2004 - 2009
Full Professor Full Time

UNIVERSIDAD DE LA FRONTERA

Medicine

Temuco, Chile

2010 - 2013
Full professor Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Medicine

Santiago, Chile

2012 - A la fecha

Professor Part Time

Universidad de la Frontera

Temuco, Chile

1995 - 2013
Surgical Pathologist Full Time

Hospital Regional Temuco

Temuco, Chile

1995 - 2012
Surgical Pathologist Full Time

Pontificia Universidad Catolica de Chile

SAntiago, Chile

2012 - A la fecha
Professor , Chair Department of pathology Full Time

Pontificia Universidad Catolica de Chile

Santiago, Chile

2012 - A la fecha

Tutor de tesis de Doctorado y Posdoctorado.
1.- Efecto de la modulación de la expresión de reprimo (RPRM) sobre el comportamiento tumoral en líneas celulares de cáncer de mama. Ph.D.c Kurt Buchegger. Molecular Biology PhD. Program. Universidad de la Frontera. 2016
2.- Detección del Virus Papiloma Humano (HPV) en DNA transrenal como herramienta de diagnóstico temprano en Cáncer Cérvicouterino. Ph.D.c Ismael Riquelme. Molecular Biology PhD. Program. Universidad de la Frontera. 2015
3.- Rol de miR-335 y miR-597 en la inactivación del gen Reprimo en cáncer gástrico. Ph.D.c Alejandra Sandoval. Molecular Biology PhD. Program. Universidad de la Frontera. 2017
4.- Reprimo como potencial Gen Supresor de Tumores en Cáncer Gástrico. Ph.D.c Kathleen Saavedra. Molecular Biology PhD. Program. Universidad de la Frontera. 2016.
5.- Inactivation of ErbB3 expression due to miRNAs deregulation in cancer of the gallbladder and its effect on tumor behavior.Jaime Patricio Lopez (Master in Sciences). Molecular Biology PhD. Program. Universidad de la Frontera. 2009-2012.
6.- Identification of Epigenomic Biomarkers of diagnosis and progression in Cervical Carcinogenesis. Ph.D. Priscilla Brebi. Molecular Biology PhD. Program. Universidad de la Frontera. 2008-2011.
7.- c-FLIP (celular FLICE-like inhibitory protein) characterization as diagnosis or prognosis biomarker in preneoplastic and neoplastic cervical lesions. Ph.D. Carmen Gloria Ili. Molecular Biology PhD. Program. Universidad de la Frontera. 2008-2011.
8.- Characterization of CTGF ( connective tissue growth factor) in GBC ant its effects in cellular invasión, tumoral behavior. Ph.D. Patricia Alejandra García Muñoz. Molecular Biology PhD. Program. Universidad de la Frontera. 2008-2011.
9.- Obtaining genic expression profiles from colon cancer by microarray technology. Ph.D Felipe Benavente Muñoz. Molecular Biology PhD. Program. Universidad de la Frontera. 2006-2010.
10.- Set up and use of Proteomics techniques in Gallbladder and gastric carcinogénesis Study. Postdoctoral Research. PhD. Fulgencio Espejel Carrasco. Postdoctorade PBCT- Academy Insertion. 2006-2009.
11.- Ubiquitine-ligase SCF complex FBW7 Protein expression , As potencial therapeutic target in gastric cancer. Postdoctoral Research. PhD. Pamela Alejandra Leal Rojas. Postdoctorade PBCT- Academy Insertion. 2006-2009.
12.- Patterns of promoter genic methylation in preneoplastic and neoplastic lesions of gallbladder. Patricia Alejandra García Muñoz (Master in Sciences). Molecular Biology PhD. Program. Universidad de la Frontera. 2005-2007.
13.- Perfil de metilación de genes supresores de tumores como factor pronóstico en pacientes con leucemia Mieloide Aguda. Soledad Reyes (Master in Sciences). Molecular Biology PhD. Program. Universidad de la Frontera. 2008-2010.
14.-Efecto en la modulacion de la expresion de mir-1 y mir-145 sobre el comportamiento tumoral in vitro y sus potenciales target de accion en el cancer de Vesicula biliar .Molecular Biology PhD. Program. Universidad de la Frontera .Pablo letelier PhD 2009-2014
15.-Transcriptomic profiling of gallbladder cancer progression. Molecular Biology Conicyt Postdoctorado. Pontificia Universidad Catolica de Chile. 2013-2016 Jaime Espinoza PhD
16.-Identification and validation of prognostic biomarkers and potential therapeutic targets of the Hippo signaling pathway in gallbladder cancer patients. Conicyt Postdoctorado. Pontificia Universidad Catolica de ChileCarolina Bizama. 2013 -2016.
17.-Desmetilación específica de regiones promotoras de genes involucrados en la resistencia a Carboplatino y/o Paclitaxel en líneas celulares de cáncer de ovario, mediante la utilización de ATFs como mecanismo de reversión del fenotipo resistente. Molecular Biology PhD. Program. Universidad de la Frontera. 2014-19. Tamara Vizcarra.
18.-Evaluación del efecto de polifenoles y terpenoides, aislados de los hongos Cyttaria espinosae y Grifola gargal, sobre el comportamiento tumoral in vitro en células de cáncer de gástrico y colorrectal. Molecular Biology PhD. Program. Universidad de la Frontera. 2014-19 Ramon Silva.
19.- Evaluación de los mecanismos moleculares de resistencia a la terapia fotodinámica in vitro y su potencial aplicación como marcadores en el tratamiento de lesiones preneoplásicas y neoplásicas de cáncer de piel no melanoma.Molecular Biology PhD. Program. Universidad de la Frontera. Daniela Leon 2013-2020
20.-Detection of DNA Methylation Biomarkers for early detection and/or progression in women with cervical preneoplastic and neoplastic lesions. A Phase I and II Biomarker Development Trial.Molecular Biology PhD. Program. Universidad de la Frontera Rene Hofftetter 2012-2018.
21.-Caracterización de la respuesta inflamatoria asociada al desarrollo de lesiones pre-neoplásicas en un modelo murino de cáncer de vesícula biliar inducido por dieta litogénica. Molecular Biology PhD. Program. Universidad de la Frontera .Lorena Rosa PhD 2016-2020.
22.- The role of vegf-r3 pathway switch induced by m2-like tumour Associated acrophages on the development of a pro-metastatic Phenotype in papillary thyroid carcinoma” Medical Sciences PhD Program PUC . Sergio Vargas 2016-2021
23 Evaluacio?n de la supresio?n de la respuesta inmune antitumoral mediada por linfocitos T en organoides derivados de pacientes con ca?ncer de vesi?cula biliar ". Medical Sciences PhD Program PUC . Javiera Obreque 2018-

Participación en comisión de tesis de doctorado 15 Ultimos 3 años (5)
Tesis de pregrado en lols ultimos 3 años (0)

Dr. Roa is a surgical and molecular Pathologist with extensive experience in biobanking and bioarchives, which are essential for the success of this project. Dr. Roa is one of the founder of the first biobank in Chile and is currently setting up the first biobank national network in Chile. He already has organized a Bioarchive in 2 different institutions and he is currently in-charge of the facilities dedicated to make tissue microarrays (TMA) blocks from different tumors. He has a completely characterized breast cancer cohort (clinical data and followup) and has currently recruited 1,000 patients with this disease. His molecular pathology lab is devoted to the identification and validation of biomarkers in gastrointestinal (gallbladder and gastric) and gynecological (breast and cervix cancer) tumors focusing on genetic predisposition, early diagnosis, prognosis and target. He has been PI and Co-PI on several gallbladder, cervix uterine cancer grants funded by the CORFO and Fondecyt programs. He has published over 150 peer reviewed scientific papers and numerous book chapters in the field. He is director of the Molecular Pathology Laboratory and former Director of Postgraduate and Research at the School of Medicine at Universidad de La Frontera. Since 2012, He is Director of the Department of Pathology at the Faculty of Medicine and PI of the Molecular Pathology Research Laboratory at Pontificia Universidad Católica de Chile and member of a study group on medicine for Fondecyt Program and a member of the academic committee of the Molecular Biology and the Medical Sciences doctoral programs.

Patents

1.-Novel Genes and uses thereof, expresion profile of colon, gastric and pancreatic 61/404,141 ( USA) 2011.
2.-Kit de deteccion y genotipificacion de HPV. “HPV easy typing” 765-2015 ( INAPI) via PCT
3.-Solicitud de Patente PCT/IB2017/051265 “Kit de detección de enfermedades de transmisión sexual silentes (ETSS) en muestra de orina” en el World Intellectual Property Organization (WIPO) con fecha 03 de marzo de2017. Número de referencia W2017-9816.
4.-Registro de marca “ITS Uridetective” N° 1242125 en el Instituto Nacional de Propiedad Intelectual (INAPI) Con fecha 23/12/2016.
5.-Derecho de autor de Temuco, la propiedad de Obra Literaria (manual) N° 279157 titulada: “Manual de usuario. ITS uridetective, detección de ITS en muestras de orina” inscrita el 16/06/2017 en el Departamento de derechos intelectuales de la Dirección de Bibliotecas, Archivos y Museos.
6.-Solicitud de Patente PCT/IB2019054042 “composición de uso tópico para terapia fotodinámicas en el World Intellectual Property Organization (WIPO) con fecha 15 de Mayo de 2019.

Invitacion a Congresos

1. CONGRESO EUROPEO DE PATOLOGIA ECP. BILBAO ESPAÑA SEPTIEMBRE 2018

2. ACADEMIA INTERNACIONAL DE PATOLOGIA JORDANIA OCTUBRE 2018.

3. CONGRESO CIRUJANOS (CANCER GASTRICO) 2018 PUERTO VARAS

4. CONGRESO DE CANCEROLOGIA 2018 (CANCER DE VESICULA BILIAR) VIÑA DE LA MAR

5. CONGRESO DE GASTROENTEROLOGIA (2018) CONSENSO PANCREAS . PUERTO VARAS

6. CURSO UNIVERSIDAD DE CHILE BIOPSIA LIQUIDA.(2018) SANTIAGO

7. GOCCHI CANCER DE VESICULA BILIAR (2018) SANTIAGO COLEGIO MEDICO

8. SAN BORJA ARRIARAN SERVICIO DE CIRUGIA NOVIEMBRE (2018 ) CANCER DE VESICULA BILIAR. SANTIAGO

9. ENCUENTRO CHILE-SUECIA SANTIAGO UNIVERSIDAD DE CHILE 2018 GBC.

10. CONGRESO LATINOAMERICANO DE PATOLOGIA LIMA. CANCER DE VESIUCLA BILIAR OCTUBRE 2019.

11. MEETING ESCALON, CORDOBA, ARGENTINA NOVIEMBRE 2019

12. VIDEO ZOOM CONFERENCE UNIVERSIDAD DE MINESSOTA ENERO 2021

Scientific Productivity Award

UNIVERSIDAD DE LA FRONTERA

Chile, 2011

Scientific Productivity Award. 2002-2011
Chilean Gastroenterology Congress Award

SOCIEDAD CHILENA DE GASTROENTEROLOGIA

Chile, 2003

Best Presentation Award 2001-2003
Chilean Academy of Medicine Award

ACADEMIA CHILENA DE MEDICINA

Chile, 2001

Chilean Academy of Medicine Award, collaborator.
Scientific Productivity Award

UNIVERSIDAD DE LA FRONTERA

Chile, 2001

Best Scientific Productivity 1997-2001
Gonzalo Tolosa Award

Gonzalo Tolosa Award

Chile, 1991

The best medicine graduate student
Cautin Medical Society Award

Cautin Medical Society Award

Chile, 1989

For Investigative Pathology
EXPERTSCAPE

WWW.EXPERTSCAPE.com

Estados Unidos, 2020

Ranked Number 1 researcher / expertise in gallbladder worldwide.
Mejor Investigador. Escuela Medicina

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile, 2021

Mejor Investigador 2021. Escuela de Medicna
Premio Investigación médica 2024

ACADEMIA CHILENA DE MEDICINA

Chile, 2024

Premio al investigador por una linea de investigacion , prolongada y exitosa con impacto en la generacion de nuevo conocimiento y en la salud de las personas.
Expertscape

www.expertscape.com

Estados Unidos, 2024

Rankeado como el investigador numero 2 a nivel mundial en cancer de vesicula biliar.


Environmental and Lifestyle Risk Factors in the Carcinogenesis of Gallbladder Cancer Perez-Moreno, Pablo; Riquelme, Ismael; Garcia, Patricia; Brebi, Priscilla; Roa, Juan Carlos Article ISI JOURNAL OF PERSONALIZED MEDICINE (2022)
The Emerging Role of PIWI-Interacting RNAs (piRNAs) in Gastrointestinal Cancers: An Updated Perspective Riquelme, Ismael; Perez-Moreno, Pablo; Letelier, Pablo; Brebi, Priscilla; Roa, Juan Carlos Article ISI CANCERS (2022)
D-PROPRANOLOL IMPAIRS EGFR TRAFFICKING AND DESTABILIZES MUTANT P53 COUNTERACTING AKT SIGNALING AND TUMOR MALIGNANCY Barra J, Cerda-Infante J, Sandoval L, Gajardo-Meneses P, Henriquez JF, Labarca M, Metz C, Venegas J, Retamal C, Oyanadel C, Cancino J, Soza A, Cuello MA, Roa JC, Montecinos VP, Gonzalez A. Article CANCERS (2021)
Dysplasia and carcinoma of the gallbladder: pathological evaluation, sampling, differential diagnosis and clinical implications Roa, Juan C.; Basturk, Olca; Adsay, Volkan Article ISI HISTOPATHOLOGY (2021)
GALLBLADDER REPORTING AND DATA SYSTEM (GB-RADS) FOR RISK STRATIFICATION OF GALLBLADDER WALL THICKENING ON ULTRASONOGRAPHY: AN INTERNATIONAL EXPERT CONSENSUS Gupta P, Dutta U, Rana P, Singhal M, Gulati A, Kalra N, Soundararajan R, Kalage D, Chhabra M, Sharma V, Gupta V, Yadav TD, Kaman L, Irrinki S, Singh H, Sakaray Y, Das CK, Saikia U, Nada R, Srinivasan R, Sandhu MS, Sharma R, Shetty N, Eapen A, Kaur H, Kamb Article Abdom Radiol (NY (2021)
Integrative molecular characterisation of gallbladder cancer reveals micro-environment-associated subtypes Nepal, Chirag; Zhu, Bin; O'Rourke, Colm J.; Bhatt, Deepak Kumar; Lee, Donghyuk; Song, Lei; Wang, Difei; Van Dyke, Alison L.; Choo-Wosoba, Hyoyoung; Liu, Zhiwei; Hildesheim, Allan; Goldstein, Alisa M.; Dean, Michael; LaFuente-Barquero, Juan; Lawrence, Scott; Mutreja, Karun; Olanich, Mary E.; Bermejo, Justo Lorenzo; Ferreccio, Catterina; Roa, Juan Carlos; Rashid, Asif; Hsing, Ann W.; Gao, Yu-Tang; Chanock, Stephen J.; Araya, Juan Carlos; Andersen, Jesper B.; Koshiol, Jill; CGR Exome Studies Grp Article ISI JOURNAL OF HEPATOLOGY (2021)
Mucocutaneous Manifestations in Autoimmune Gastritis: A Prospective Case-Control Study Gonzalez, Agustin; Latorre, Gonzalo; Paredes, Loreto; Montoya, Lorena; Maquilon, Sara; Shah, Shailja C.; Espino, Alberto; Sabatini, Natalia; Torres, Javiera; Roa, Juan Carlos; Riquelme, Arnoldo; Kolbach, Marianne Article ISI AMERICAN JOURNAL OF GASTROENTEROLOGY (2021)
Role of lncRNAs in the Development of an Aggressive Phenotype in Gallbladder Cancer Perez-Moreno, Pablo; Riquelme, Ismael; Brebi, Priscilla; Roa, Juan Carlos Article ISI Journal of Clinical Medicine (2021)
T2 gallbladder cancer shows substantial survival variation between continents and this is not due to histopathologic criteria or pathologic sampling differences DeSimone, Mia S.; Goodman, Michael; Pehlivanoglu, Burcin; Memis, Bahar; Balci, Serdar; Roa, Juan Carlos; Jang, Kee-Taek; Jang, Jin-Young; Hong, Seung-Mo; Lee, Kyoungbun; Kim, Haeryoung; Choi, Hye-Jeong; Muraki, Takashi; Araya, Juan Carlos; Bellolio, Enrique; Sarmiento, Juan M.; Maithel, Shishir K.; Losada, Hector F.; Basturk, Olca; Reid, Michelle D.; Koshiol, Jill; Adsay, Volkan Article ISI VIRCHOWS ARCHIV (2021)
A Thyroid Genetic Classifier Correctly Predicts Benign Nodules with Indeterminate Cytology: Two Independent, Multicenter, Prospective Validation Trials Zafereo, Mark; McIver, Bryan; Vargas-Salas, Sergio; Miguel Dominguez, Jose; Steward, David L.; Holsinger, F. Christopher; Kandil, Emad; Williams, Michelle; Cruz, Francisco; Loyola, Soledad; Solar, Antonieta; Carlos Roa, Juan; Leon, Augusto; Droppelman, Nicolas; Lobos, Maite; Arias, Tatiana; Kong, Christina S.; Busaidy, Naifa; Grubbs, Elizabeth G.; Graham, Paul; Stewart, John; Tang, Alice; Wang, Jiang; Orloff, Lisa; Henriquez, Marcela; Lagos, Marcela; Osorio, Miren; Schachter, Dina; Franco, Carmen; Medina, Francisco; Wohllk, Nelson; Diaz, Rene E.; Veliz, Jesus; Horvath, Eleonora; Tala, Hernan; Pineda, Pedro; Arroyo, Patricia; Vasquez, Felix; Traipe, Eufrosina; Marin, Luis; Miranda, Giovanna; Bruce, Elsa; Bracamonte, Milagros; Mena, Natalia; Gonzalez, Hernan E. Article ISI THYROID (2020)
Angiotensin-(1–9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway Sotomayor-Flores C.; Rivera-MejÃas P.; VÃ¡squez-Trincado C.; LÃ³pez-Crisosto C.; Morales P.E.; Pennanen C.; Polakovicova I.; Aliaga-Tobar V.; GarcÃa L.; Roa, J.C; Rothermel, B. A.; Maracaja-Coutinho V.; Ho-Xuan H.; Meister G.; Chiong M.; Ocaranza M.P.; CorvalÃ¡n A.H.; Parra V.; Lavandero S. Article ISI SCOPUS Cell Death and Differentiation (2020)
Autophagy Activation in Zebrafish Heart Regeneration Chávez, Myra N.; Morales, Rodrigo A.; López-Crisosto, Camila; Roa, Juan Carlos; Allende, Miguel L.; Lavandero, Sergio Article SCOPUS SCIENTIFIC REPORTS (2020)
CANONICAL ERBB-2 ISOFORM AND ERBB-2 VARIANT C LOCATED IN THE NUCLEUS DRIVE TRIPLE NEGATIVE BREAST CANCER GROWTH Chervo MF, Cordo Russo RI, Petrillo E, Izzo F, De Martino M, Bellora N, Cenciarini ME, Chiauzzi VA, Santa María de la Parra L, Pereyra MG, Güttlein LN, Podhajcer OL, Daniotti JL, Dupont A, Barchuk S, Figurelli S, Lopez Della Vecchia D, Roa JC, Guzmán P, P Article (2020)
Cohort Profile: The Maule Cohort (MAUCO) Ferreccio, Catterina; Huidobro, Andrea; Cortes, Sandra; Bambs, Claudia; Toro, Pablo; Van De Wyngard, Vanessa; Acevedo, Johanna; Paredes, Fabio; Venegas, Pia; Verdejo, Hugo; Oyarzun-Gonzalez, Ximena; Cook, Paz; Castro, Pablo F.; Foerster, Claudia; Vargas, Claudio; Koshiol, Jill; Carlos Araya, Juan; Cruz, Francisco; Corvalan, Alejandro H.; Quest, Andrew F.; Kogan, Marcelo J.; Lavandero, Sergio; MAUCO Study Grp Article ISI INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2020)
Current and New Biomarkers for Early Detection, Prognostic Stratification, and Management of Gallbladder Cancer Patients Garcia, Patricia; Lamarca, Angela; Diaz, Javier; Carrera, Enrique; Roa, Juan Carlos; European-Latin Amer ESCALON Consor Article ISI CANCERS (2020)
Epigallocatechin Gallate Enhances MAL-PDT Cytotoxic Effect on PDT-Resistant Skin Cancer Squamous Cells Leon, Daniela; Buchegger, Kurt; Silva, Ramon; Riquelme, Ismael; Viscarra, Tamara; Mora-Lagos, Barbara; Zanella, Louise; Schafer, Fabiola; Kurachi, Cristina; Roa, Juan Carlos; Ili, Carmen; Brebi, Priscilla. Article ISI INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Evaluation of the chemopreventive potentials of ezetimibe and aspirin in a novel mouse model of gallbladder preneoplasia Rosa, Lorena; Lobos-Gonzalez, Lorena; Munoz-Durango, Natalia; Garcia, Patricia; Bizama, Carolina; Gomez, Natalia; Gonzalez, Ximena; Wichmann, Ignacio A.; Saavedra, Nicolas; Guevara, Francisca; Villegas, Jaime; Arrese, Marco; Ferreccio, Catterina; Kalergis, Alexis M.; Miquel, Juan Francisco; Espinoza, Jaime A.; Roa, Juan C. Article ISI MOLECULAR ONCOLOGY (2020)
Functional and genomic characterization of three novel cell lines derived from a metastatic gallbladder cancer tumor García, Patricia; Bizama, Carolina; Rosa, Lorena; Espinoza, Jaime A.; Weber, Helga; Cerda-Infante, Javier; Sánchez, Marianela; Montecinos, Viviana P.; Lorenzo-Bermejo, Justo; Boekstegers, Felix; Dávila-López, Marcela; Alfaro, Francisca; Leiva-Acevedo, Claudia; Parra, Zasha; Romero, Diego; Kato, Sumie; Leal, Pamela; Lagos, Marcela; Roa, Juan Carlos Article Biological Research volume (2020)
Gallbladder polyps: Correlation of size and clinicopathologic characteristics based on updated definitions Taskin, Orhun C.; Basturk, Olca; Reid, Michelle D.; Dursun, Nevra; Bagci, Pelin; Saka, Burcu; Balci, Serdar; Memis, Bahar; Bellolio, Enrique; Araya, Juan Carlos; Roa, Juan Carlos; Tapia, Oscar; Losada, Hector; Sarmiento, Juan; Jang, Kee-Taek; Jang, Jin-Young; Pehlivanoglu, Burcin; Erkan, Mert; Adsay, Volkan Article ISI PLOS ONE (2020)
Hippo-YAP1 Is a Prognosis Marker and Potentially Targetable Pathway in Advanced Gallbladder Cancer García, Patricia; Rosa, Lorena; Vargas, Sergio; Weber, Helga; Espinoza, Jaime A.; Suárez, Felipe; Romero-Calvo, Isabel; Elgueta, Nicole; Rivera, Vanessa; Nervi, Bruno; Obreque, Javiera; Leal, Pamela; Viñuela, Eduardo; Aguayo, Gloria; Muñiz, Sabrina; Sagredo, Alfredo; Roa, Juan C.; Bizama, Carolina Article ISI SCOPUS Cancers (2020)
Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate Pandey, Akhilesh; Stawiski, Eric W.; Durinck, Steffen; Gowda, Harsha; Goldstein, Leonard D.; Barbhuiya, Mustafa A.; Schroeder, Markus S.; Sreenivasamurthy, Sreelakshmi K.; Kim, Sun-Whe; Phalke, Sameer; Suryamohan, Kushal; Lee, Kayla; Chakraborty, Papia; Kode, Vasumathi; Shi, Xiaoshan; Chatterjee, Aditi; Datta, Keshava; Khan, Aafaque A.; Subbannayya, Tejaswini; Wang, Jing; Chaudhuri, Subhra; Gupta, Sanjiv; Shrivastav, Braj Raj; Jaiswal, Bijay S.; Poojary, Satish S.; Bhunia, Shushruta; Garcia, Patricia; Bizama, Carolina; Rosa, Lorena; Kwon, Wooil; Kim, Hongbeom; Han, Youngmin; Yadav, Thakur Deen; Ramprasad, Vedam L.; Chaudhuri, Amitabha; Modrusan, Zora; Roa, Juan Carlos; Tiwari, Pramod Kumar; Jang, Jin-Young; Seshagiri, Somasekar Article ISI NATURE COMMUNICATIONS (2020)
NEOPLASMS ARISING IN ADENOMYOMATOUS NODULES OF THE GALLBLADDER: AN ANALYSIS OF 19 EXAMPLES Rowan DJ, Pehlivanoglu B, Memis B, Bagci P, Erbarut I, Dursun N, Jang KT, Sarmiento J, Mucientes F, Cheng JD, Roa JC, Araya JC, Bellolio E, Losada H, Jang JY, Koshiol J, Reid MD, Basturk O, Adsay V Article (2020)
Non-neoplastic Polyps of the Gallbladder: A Clinicopathologic Analysis of 447 Cases Taskin O.C.; Bellolio E.; Dursun N.; Seven I.E.; Roa, J.C; Araya J.C.; Villaseca M.; Tapia O.; Vance C.; Saka B.; Balci, S; Bagci P.; Losada H.; Sarmiento J.; Memis B.; Pehlivano?lu B.; Basturk O.; Reid M.D.; Koshiol J.; Cheng J.D.; Kapran Y.; Adsay V. Article SCOPUS The American journal of surgical pathology (2020)
Phylogenetic dating analysis of HTLV-1 from Chile suggests transmissions events related to ancient migrations and contemporary expansion Zanella, Louise; Riquelme, Ismael; Elena Reyes, Maria; Jose Tapia, Maria; Reyes, Soledad; Mora, Barbara; Viscarra, Tamara; Carlos Roa, Juan; Ili, Carmen; Brebi, Priscilla. Article ISI INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)
RNA-SEQUENCING OF HEPATOBILIARY CANCER CELL LINES: DATA AND APPLICATIONS TO MUTATIONAL AND TRANSCRIPTOMIC PROFILING Scherer D, Dávila López MD, Goeppert B, Abrahamsson S, González Silos RG, Nova I, Marcelain K, Roa JC, Ibberson D, Umu SU, Rounge TB, Roessler S, Bermejo J Article CANCERS (2020)
The Anti-Proliferative and Anti-Invasive Effect of Leaf Extracts of Blueberry Plants Treated with Methyl Jasmonate on Human Gastric Cancer In Vitro Is Related to Their Antioxidant Properties Ribera-Fonseca, Alejandra; Jimenez, Danae; Leal, Pamela; Riquelme, Ismael; Carlos Roa, Juan; Alberdi, Miren; Peek, Richard M.; Reyes-Diaz, Marjorie Article ISI SCOPUS ANTIOXIDANTS (2020)
The Chile Biliary Longitudinal Study: A Gallstone Cohort Koshiol, Jill; Van De Wyngard, Vanessa; McGee, Emma E; Cook, Paz; Pfeiffer, Ruth M; Mardones, Noldy; Medina, Karie; Olivo, Vanessa; Pettit, Karen; Jackson, Sarah S; Paredes, Fabio; Sanchez, Raúl; Huidobro, Andrea; Villaseca, Miguel; Bellolio, Enrique; Losada, Hector; Roa, Juan Carlos; Hildesheim, Allan; Araya, Juan Carlos; Ferreccio, Catterina Article American Journal of Epidemiology (2020)
Transcriptomic profiles reveal differences in zinc metabolism, inflammation, and tight junction proteins in duodenum from cholesterol gallstone subjects Riveras, Eleodoro; Azocar, Lorena; Moyano, Tomas C.; Ocares, Marcia; Molina, Hector; Romero, Diego; Roa, Juan C.; Valbuena, Jose R.; Gutiérrez, Rodrigo A.; Miquel, Juan F. Article SCIENTIFIC REPORTS (2020)
Carcinogenic Strains Selectively Dysregulate the Gastric Proteome, Which May Be Associated with Stomach Cancer Progression. Noto, Jennifer M; Rose, Kristie L; Hachey, Amanda J; Delgado, Alberto G; Romero-Gallo, Judith; Wroblewski, Lydia E; Schneider, Barbara G; Shah, Shailja C; Cover, Timothy L; Wilson, Keith T; Israel, Dawn A; Roa, Juan Carlos; Schey, Kevin L; Zavros, Yana; Piazuelo, M Blanca; Peek, Richard M Article Molecular & cellular proteomics => MCP (2019)
Carcinogenic Helicobacter pylori Strains Selectively Dysregulate the In Vivo Gastric Proteome, Which May Be Associated with Stomach Cancer Progression Noto, JM; Rose, KL; Hachey, AJ; Delgado, AG; Romero-Gallo, J; Wroblewski, LE; Schneider, BG; Shah, SC; Cover, TL; Wilson, KT; Israel, DA; Roa, JC; Schey, KL; Zavros, Y; Piazuelo, MB; Peek, RM Article Molecular and Cellular Proteomics (2019)
Fibroblast Primary Cilia Are Required for Cardiac Fibrosis Villalobos, Elisa; Criollo, Alfredo; Schiattarella, Gabriele G.; Altamirano, Francisco; French, Kristin M.; May, Herman, I; Jiang, Nan; Ngoc Uyen Nhi Nguyen; Romero, Diego; Carlos Roa, Juan; Garcia, Lorena; Diaz-Araya, Guillermo; Morselli, Eugenia; Ferdous, Anwarul; Conway, Simon J.; Sadek, Hesham A.; Gillette, Thomas G.; Lavandero, Sergio; Hill, Joseph A Article ISI SCOPUS CIRCULATION (2019)
Functional and transcriptomic characterization of carboplatin-resistant A2780 ovarian cancer cell line Viscarra, T; Buchegger, K; Jofre, I.; Riquelme, I; Zanella, L; Abanto, M; Parker, AC; Piccolo, SR; Roa, JC; Ili, C; Brebi, P Article ISI SCIELO SCOPUS BIOLOGICAL RESEARCH (2019)
Functional and transcriptomic characterization of carboplatin-resistant A2780 ovarian cancer cell line Viscarra, T; Buchegger, K; Jofre, I; Riquelme, I; Zanella, L; Abanto, M; Parker, AC; Piccolo, SR; Roa, JC; Ili, C; Brebi, P Article Biological research (2019)
Interleukin 33/ST2 Axis Components Are Associated to Desmoplasia, a Metastasis-Related Factor in Colorectal Cancer Landskron, Glauben; De la Fuente Lopez, Marjorie; Dubois-Camacho, Karen; Diaz-Jimenez, David; Orellana-Serradell, Octavio; Romero, Diego; Sepulveda, Santiago A.; Salazar, Christian; Parada-Venegas, Daniela; Quera, Rodrigo; Simian, Daniela; Gonzalez, Maria-Julieta; Kronberg, Udo; Abedrapo, Mario; Gallegos, Ivan; Contreras, Hector R.; Pena, Cristina; Diaz-Araya, Guillermo; Carlos Roa, Juan; Hermoso, Marcela A. Article ISI SCOPUS FRONTIERS IN IMMUNOLOGY (2019)
Loss of ZNF516 protein expression is related with HR-HPV infection and cervical preneoplastic lesions Ili, C; Lopez, J; Buchegger, K; Riquelme, I; Retamal, J; Zanella, L; Mora-Lagos, B; Vivallo, C; Roa, JC; Brebi, P Article ARCHIVES OF GYNECOLOGY AND OBSTETRICS (2019)
Mucin 5B, carbonic anhydrase 9 and claudin 18 are potential theranostic markers of gallbladder carcinoma Espinoza, Jaime A.; Riquelme, Ismael; Sagredo, Eduardo A.; Rosa, Lorena; Garcia, Patricia; Bizama, Carolina; Apud-Bell, Maria; Leal, Pamela; Weber, Helga; Benavente, Felipe; Vargas, Sergio; Romero, Diego; Kalergis, Alexis M; Carlos Roa, Juan Article ISI SCOPUS HISTOPATHOLOGY (2019)
PIM1 kinase promotes gallbladder cancer cell proliferation via inhibition of proline-rich Akt substrate of 40kDa (PRAS40) Subbannayya T.; Leal-Rojas P.; Zhavoronkov A.; Ozerov I.V.; Korzinkin M.; Babu N.; Radhakrishnan A.; Chavan S.; Raja R.; Pinto S.M.; Patil A.H.; Barbhuiya M.A.; Kumar P.; Guerrero-Preston R.; Navani S.; Tiwari P.K.; Kumar R.V.; Prasad T.S.K.; Roa, J.C; Pandey A.; Sidransky D.; Gowda H.; Izumchenko E.; Chatterjee A. Article ISI SCOPUS Journal of Cell Communication and Signaling (2019)
Sarcomatoid carcinomas of the gallbladder: clinicopathologic characteristics Taskin O.C.; Akkas G.; Memis B.; Seven I.E.; Basturk O.; Jang K.-T.; Roa, J.C; Araya J.C.; Bellolio E.; Losada H.; Sarmiento J.; Balci, S; Pehlivanoglu B.; Reid M.D.; Koshiol J.; Adsay V. Article ISI SCOPUS VIRCHOWS ARCHIV (2019)
Tolerogenic dendritic cell transfer ameliorates systemic lupus erythematosus in mice Funes S.C.; RÃos M.; GÃ³mez-Santander F.; FernÃ¡ndez-Fierro A.; Altamirano-Lagos M.J.; Rivera-Perez D.; Pulgar-SepÃºlveda R.; Jara E.L.; Rebolledo-Zelada D.; Villarroel A.; Roa, J.C; Mackern-Oberti J.P.; Kalergis A.M. Article ISI SCOPUS IMMUNOLOGY (2019)
Variants in ABCG8 and TRAF3 genes confer risk for gallstone disease in admixed Latinos with Mapuche Native American ancestry Bustos, BI; Perez-Palma, E; Buch, S; Azocar, L; Riveras, E; Ugarte, GD; Toliat, M; Nurnberg, P; Lieb, W; Franke, A; Hinz S.; Burmeister, G; von Schonfels, W; Schafmayer C.; Volzke, H; Volker, U; Homuth, G; Lerch, MM; Santos, JL; Puschel, K; Bambs, C; Roa, JC; gutierrez ra; Hampe, J; De Ferrari, GV; Miquel, JF Article ISI SCOPUS SCIENTIFIC REPORTS (2019)
Variants in ABCG8 and TRAF3 genes confer risk for gallstone disease in admixed Latinos with Mapuche Native American ancestry Bustos, BI; Perez-Palma, E; Buch, S; Azocar, L; Riveras, E; Ugarte, GD; Toliat, M; Nurnberg, P; Lieb, W; Franke, A; Hinz, S; Burmeister, G; von Schonfels, W; Schafmayer, C; Volzke, H; Volker, U; Homuth, G; Lerch, MM; Santos, JL; Puschel, K; Bambs, C; Roa, JC; Gutierrez, RA; Hampe, J; De Ferrari, GV; Miquel, JF Article Scientific Reports (2019)
Circulating Levels of Inflammatory Proteins and Survival in Patients with Gallbladder Cancer Liu, ZW; Kemp, TJ; Gao, YT; Corbel, A; McGee, EE; Roa, Jc; Wang, BS; Araya, JC; Shen, MC; Rashid, A; Hsing, AW; Hildesheim, A; Ferreccio, C; Pfeiffer, RM; Pinto, LA; Koshiol, J Article ISI SCOPUS SCIENTIFIC REPORTS (2018)
Detection and genotyping of human papillomavirus virus (HPV)=> a comparative analysis of clinical performance in cervical and urine samples in Chilean women Buchegger, K; Viscarra, T; Andana, A; Ili, C; Lopez, J; Zanella, L; Carmona-Lopez, MI; Fernandez, JJ; Espinel, IC; Sanchez, R; Roa, JC; Brebi, P Article INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY (2018)
Detection and genotyping of human papillomavirus virus (HPV)=> a comparative analysis of clinical performance in cervical and urine samples in Chilean women Buchegger, K; Viscarra, T; Andana, A; Ili, C; Lopez, J; Zanella, L; Carmona-Lopez, MI; Fernandez, JJ; Espinel, IC; Sanchez, R; Roa, JC; Brebi, P Article INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY (2018)
Differential expression profile of CXCR3 splicing variants is associated with thyroid neoplasia. Potential role in papillary thyroid carcinoma oncogenesis? Urra, Soledad; Fischer, Martin C.; Martinez, Jose R.; Veliz, Loreto; Orellana, Paulina; Solar, Antonieta; Bohmwald, Karen; Kalergis, Alexis; Riedel, Claudia; Corvalan, Alejandro H.; Roa, Juan C.; Fuentealba, Rodrigo.; Caceres, C. Joaquin; Lopez-Lastra, Marcelo; Leon, Augusto; Droppelmann, Nicolas; Gonzalez, Hernan E. Article ISI SCOPUS ONCOTARGET (2018)
Distribution of dysplasia and cancer in the gallbladder: an analysis from a high cancer-risk population Koshiol J.; Bellolio E.; Vivallo C.; Cook, P; Roa, J.C; McGee E.E.; Losada H.; Van Dyke A.L.; Van De Wyngard V; Prado R.; Villaseca M.; Riquelme P.; Acevedo J.; Olivo V.; Pettit K.; Hildesheim A.; Medina K.; Memis B.; Adsay V.; Ferreccio C.; Araya J.C. Article ISI SCOPUS Human Pathology (2018)
Galectin-8 induces partial epithelial-mesenchymal transition with invasive tumorigenic capabilities involving a FAK/EGFR/proteasome pathway in Madin-Darby canine kidney cells Oyanadel, Claudia; Holmes, Christopher; Pardo, Evelyn; Retamal, Claudio; Shaughnessy, Ronan; Smith, Patricio; Cortés, Priscilla; Bravo-Zehnder, Marcela; Metz, Claudia.; Feuerhake, Teo; Romero, Diego; Roa, Juan Carlos; Montecinos, Viviana; Soza, Andrea; González, Alfonso; Yamashita, Yukiko Article ISI SCOPUS MOLECULAR BIOLOGY OF THE CELL (2018)
Optimal surgical treatment in patients with T1b gallbladder cancer: An international multicenter study Kim, H. S.; Park J.W.; Kim H.; Han, Y; Kwon W.; Kim S.-W.; Hwang Y.J.; Kim S.G.; Kwon H.J.; Vinuela E.; JÃ¡rufe N.; Roa, J.C; Han I.W.; Heo J.S.; Choi S.-H.; Choi D.W.; Ahn K.S.; Kang K.J.; Lee, W.; Jeong C.-Y.; Hong S.-C.; Troncoso A.; Losada H.; Han S.-S.; Park S.-J.; Yanagimoto H.; Endo I.; Kubota K.; Wakai T.; Ajiki T.; Adsay N.V.; Jang J.-Y. Article ISI SCOPUS Journal of Hepato-Biliary-Pancreatic Sciences (2018)
Patient inflammatory status and CD4+/CD8+ intraepithelial tumor lymphocyte infiltration are predictors of outcomes in high-grade serous ovarian cancer Pinto, M. P.; Balmaceda C.; Bravo, M. L.; Kato S.; Villarroel A.; Owen, G. I.; Roa, J.C; Cuello, M. A.; IbaÃ±ez C. Article ISI SCOPUS Gynecologic Oncology (2018)
Simvastatin interferes with cancer stem-cell plasticity reducing metastasis in ovarian cancer Kato, S; Liberona, MF; Cerda-Infante, J; Sanchez, M; Henriquez, J; Bizama, C; Bravo, ML; Gonzalez, P; Gejman, R; Branes, J; Garcia, K; Ibanez, C; Owen, GI; Roa, JC; Montecinos, V; Cuello, MA Article ENDOCRINE-RELATED CANCER (2018)
The relationship between chemokines CCL2, CCL3, and CCL4 with the tumor microenvironment and tumor-associated macrophage markers in colorectal cancer De la Fuente LÃ³pez M.; Landskron G.; Parada, D; Dubois-Camacho K.; Simian D.; Martinez M.; Romero D.; Roa, J.C; ChahuÃ¡n I.; GutiÃ©rrez R.; Lopez-K F.; Alvarez K.; Kronberg U.; LÃ³pez S.; Sanguinetti A.; Moreno, N; Abedrapo M.; GonzÃ¡lez M.-J.; Quera R.; Hermoso-R M.A. Article SCOPUS Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine (2018)
Tumor lysate-based vaccines: on the road to immunotherapy for gallbladder cancer Rojas-Sepulveda, Daniel; Tittarelli, Andres; Alejandra Gleisner, Maria; Avalos, Ignacio; Pereda, Cristian; Gallegos, Ivan; Eduardo Gonzalez, Fermin; Natalia Lopez, Mercedes; Michel Butte, Jean; Carlos Roa, Juan; Fluxa, Paula; Salazar-Onfray, Flavio Article ISI SCOPUS CANCER IMMUNOLOGY IMMUNOTHERAPY (2018)
Biliary tract cancer Koshiol J.; Ferreccio C.; Devesa S.S.; Roa, J.C; Fraumeni J.F.; Jr. Article SCOPUS Schottenfeld and Fraumeni Cancer Epidemiology and Prevention, Fourth Edition (2017)
Evaluation of DNA methylation in promoter regions of SFRP4 and ZAR1 in urine and plasma of women with cervical lesions Hoffstetter R; Riquelme I.; Brebi P.; Andana, A; Ili CG; Buchegger, K; VARGAS H.; Roa, Jc Article ISI SCOPUS TRANSLATIONAL CANCER RESEARCH (2017)
Frequency of Human papillomavirus in women attending cervical cancer screening program in Chile Brebi, Priscilla; Ili, Carmen Gloria; Andana, Alejandra; Menzel, Doris; Lopez, Jaime; Guzman, Pablo; Melo, Angelica; Buchegger, Kurt; Roa, Juan C. Article ISI SCOPUS BMC CANCER (2017)
Herpud1 negatively regulates pathological cardiac hypertrophy by inducing IP3 receptor degradation Torrealba, N; Navarro-Marquez, M; Garrido, V; Pedrozo, Z; Romero, D; Eura, Y; Villalobos, E; Roa, JC; Chiong, M; Kokame, K; Lavandero, S Article ISI SCOPUS SCIENTIFIC REPORTS (2017)
High intraspecific variability of Echinococcus granulosus sensu stricto in Chile Alvarez Rojas, Cristian A.; Ebi, Dennis; Paredes, Rodolfo; Acosta-Jamett, Gerardo; Urriola, Nicole; Roa, Juan Carlos; Manterola, Carlos; Cortes, Sandra; Romig, Thomas; Scheerlinck, Jean-Pierre; Lightowlers, Marshall W. Article ISI SCOPUS PARASITOLOGY INTERNATIONAL (2017)
Invasive micropapillary carcinoma of the breast overexpresses MUC4 and is associated with poor outcome to adjuvant trastuzumab in HER2-positive breast cancer Mercogliano, MF; Inurrigarro, G; De Martino, M; Venturutti, L; Rivas, MA; Cordo-Russo, R; Proietti, CJ; Fernandez, EA; Frahm, I; Barchuk, S; Allemand, DH; Figurelli, S; Deza, EG; Ares, S; Gercovich, FG; Cortese, E; Amasino, M; Guzman, P; Roa, JC; Elizalde, PV; Schillaci, R Article ISI SCOPUS BMC Cancer (2017)
MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer Sandoval-Borquez, A; Polakovicova, I; Carrasco-Veliz, N; Lobos-Gonzalez, L; Riquelme, I; Carrasco-Avino, G; Bizama, C; Norero, E; Owen, GI; Roa, JC; Corvalan, AH Article ISI SCOPUS Clinical Epigenetics (2017)
Poorly cohesive cell (diffuse-infiltrative/signet ring cell) carcinomas of the gallbladder: clinicopathological analysis of 24 cases identified in 628 gallbladder carcinomas Tuncel, Deniz; Roa, Juan Carlos; Araya, Juan Carlos; Bellolio, Enrique; Villaseca, Miguel; Tapia, Oscar; Jang, Kee-Taek; Quigley, Brian; Saka, Burcu; Basturk, Olca; Sarmiento, Juan; Losada, Hector F.; Patel, Samip; Reid, Michelle D.; Memis, Bahar; Adsay, Volkan Article ISI SCOPUS HUMAN PATHOLOGY (2017)
Reprimo, a Potential p53-Dependent Tumor Suppressor Gene, Is Frequently Hypermethylated in Estrogen Receptor -Positive Breast Cancer Buchegger, Kurt; Riquelme, Ismael; Viscarra, Tamara; Ili, Carmen; Brebi, Priscilla; Huang, Tim; Roa, Juan Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer Weber, H; Valbuena, JR; Barbhuiya, MA; Stein, S; Kunkel, H; García, P; Bizama, C; Riquelme, I; Espinoza, JA; Kurtz, SE; Tyner, J; Calderon, JF; Corvalán, AH; Grez, M; Pandey, A; Leal-Rojas, P; Roa, JC Article ISI SCOPUS ONCOTARGET (2017)
The ERK/MAPK pathway is overexpressed and activated in gallbladder cancer Buchegger, Kurt; Silva, Ramón; López, Jaime; Ili, Carmen; Araya, Juan Carlos; Leal, Pamela; Brebi, Priscilla; Riquelme, Ismael; Roa, Juan Carlos Article ISI SCOPUS PATHOLOGY RESEARCH AND PRACTICE (2017)
TNF alpha-Induced Mucin 4 Expression Elicits Trastuzumab Resistance in HER2-Positive Breast Cancer Mercogliano, María F.; De Martino, Mara; Venturutti, Leandro; Rivas, Martín A.; Proietti, Cecilia J.; Inurrigarro, Gloria; Frahm, Isabel; Allemand, Daniel H.; Deza, Ernesto Gil; Ares, Sandra; Gercovich, Felipe G.; Guzmán, Pablo; Roa, Juan C.; Elizalde, Patricia V.; Schillaci, Roxana Article ISI SCOPUS CLINICAL CANCER RESEARCH (2017)
[Recommendations for the management of pancreatic cancer type adenocarcinoma=> A consensus statement reached during the 2015 Latin American Symposium on Gastroenterological Oncology]. Caglevic, Christian; Gallardo, Jorge; de la Torre, Marcela; Mahave, Mauricio; Müller, Bettina; Solé, Sebastián; Moscoso, Yuri; De La Fuente, Hernán; Roa, Juan Carlos; Hoefler, Sebastián; Butte, Jean M; González M, Pablo; O'Connor, Juan Manuel; Torres, Javiera; Pérez Encalada, Verónica; Alarcón Cano, Daniel; Ubillos, Luis; Rolfo, Christian; Lingua, Alejo; Díaz Romero, Consuelo; Padilla Rosciano, Alejandro; Cuartero, Viviana; Calderillo Ruiz, Germán; Schwartsmann, Gilberto; Kon Jara, Xavier; Andrade G, Andrés; Mas López, Luis; Barajas, Olga; Carballido, Marcela; Lembach, Hanns; Morillas G, Lena; Roca, Enrique; Lobatón, José; Montenegro B, Paola; Yepes, Andrés; Marsiglia, Hugo Article Revista medica de Chile (2016)
Association of inflammatory and other immune markers with gallbladder cancer: Results from two independent case-control studies Koshiol, J; Castro, F.; Kemp T.J.; Gao Y.-T.; Roa, J.C; Wang, B; Nogueira L.; Araya J.C.; Shen M.-C.; Rashid, A; Hsing A.W.; Hildesheim, A; Ferreccio C.; Pfeiffer R.M.; Pinto, L.A. Article ISI SCOPUS CYTOKINE (2016)
Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers Letelier, Pablo; Riquelme, Ismael; Hern?ndez, Alfonso; Guzm?n, Neftal?; Far?as, Jorge; Roa, Juan Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Immunohistochemical expression of RPRM is associated with low expression of proliferation marker Ki67 in patients with breast cancer Buchegger, K; Lopez, J.; Ili C.; Riquelme I.; Letelier P; Guzman P.; Bellolio E.; Corvalán A.H.; Brebi P.; Roa, J.C Article ISI SCOPUS INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE (2016)
Low expression of equilibrative nucleoside transporter 1 is associated with poor prognosis in chemotherapy-naive pT2 gallbladder adenocarcinoma patients Espinoza, J.A; Garcia P.; Bizama, C; Leal J.L.; Riquelme I.; Weber, H; Macanas, P.; Aguayo, G; Viñuela E.; Roa, J.C; Nervi, B Article ISI SCOPUS HISTOPATHOLOGY (2016)
miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway Riquelme I.; Tapia O.; Leal P.; Sandoval A.; Varga, MG; Letelier P; Buchegger, K; Bizama, C; Espinoza, JA; Peek, RM; Araya, JC; Roa, Jc Article ISI SCOPUS CELLULAR ONCOLOGY (2016)
MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1 Venturutti, L; Cordo Russo, R I; Rivas, M A; Mercogliano, M F; Izzo, F; Oakley, R H; Pereyra, M G; De Martino, M; Proietti, C J; Yankilevich, P; Roa, J C; Guzmán, P; Cortese, E; Allemand, D H; Huang, T H; Charreau, E H; Cidlowski, J A; Schillaci, R; Elizalde, P V Article ISI SCOPUS ONCOGENE (2016)
Pathologic Evaluation and Reporting of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Other Tumoral Intraepithelial Neoplasms of Pancreatobiliary Tract Recommendations of Verona Consensus Meeting Adsay V.; Mino-Kenudson, M; Furukawa, T; Basturk O.; Zamboni, G; Marchegiani, G; Bassi C.; Salvia R.; Malleo, G; Paiella, S; Wolfgang, CL; Matthaei, H; Offerhaus, GJ; Adham, M; Bruno, MJ; Reid, MD; Krasinskas, A; Kloppel, G; Ohike, N; Tajiri, T; Jang, KT; Roa, Jc; Allen P.; Fernandez-del Castillo, C; Jang, JY; Klimstra, DS; Hruban, RH Article ISI SCOPUS ANNALS OF SURGERY (2016)
Recommendations for the management of pancreatic cancer type adenocarcinoma. A consensus statement reached during the 2015 Latin American Symposium on Gastroenterological Oncology Caglevic, C; gallardo, J; De la Torre, M; Mahave, M; Muller, B; Sole, S; Moscoso, Y; de la Fuente, H; Roa, JC; Hoefler, S; Butte, JM; Gonzalez, P; O'Connor, JM; Torres, J; Encalada, VP; Cano, DA; Ubillos, L; Rolfo, C; Lingua, A; Romero, CD; Rosciano, AP; Cuartero, V; Ruiz, GC; Schwartsmann, G; Jara, XK; Andrade, A; Lopez, LM; Barajas, O; Carballido, M; Lembach, H; Morillas, L; Roca, E; Lobaton, J; Montenegro, P; Yepes, A; Marsiglia, H Article ISI REVISTA MEDICA DE CHILE (2016)
Reprimo as a modulator of cell migration and invasion in the MDA-MB-231 breast cancer cell line. Buchegger, Kurt; Ili, Carmen; Riquelme, Ismael; Letelier, Pablo; Corvalán, Alejandro H; Brebi, Priscilla; Huang, Tim Hui-Ming; Roa, Juan Carlos Article Biological research (2016)
RNA sequencing-based analysis of gallbladder cancer reveals the importance of the liver X receptor and lipid metabolism in gallbladder cancer Zuo M.; Rashid, A; Wang Y.; Jain, A; Li, D; Behari A.; Kapoor V.K.; Koay E.J.; Chang, P; Vauthey J.N.; Li Y.; Espinoza, J.A; Roa, J.C; Javle, M Article ISI SCOPUS ONCOTARGET (2016)
Salmonella enterica serovar Typhi and gallbladder cancer: a case-control study and meta-analysis Koshiol, Jill; Wozniak, Aniela; Cook, Paz; Adaniel, Christina; Acevedo, Johanna; Azócar, Lorena; Hsing, Ann W.; Roa, Juan C.; Pasetti, Marcela F.; Miquel, Juan F.; Levine, Myron M.; Ferreccio, Catterina Article ISI SCOPUS CANCER MEDICINE (2016)
Stat3 regulates ErbB-2 expression and co-opts ErbB-2 nuclear function to induce miR-21 expression, PDCD4 downregulation and breast cancer metastasis Venturutti L.; Romero L.V.; Urtreger A.J.; Chervo M.F.; Cordo Russo R.I.; Mercogliano M.F.; Inurrigarro G.; Pereyra M.G.; Proietti C.J.; Izzo F.; Díaz Flaqué M.C.; Sundblad V.; Roa, J.C; Guzman P.; Bal De Kier Joffé E.D.; Charreau E.H.; Schillaci R.; Elizalde P.V. Article ISI SCOPUS ONCOGENE (2016)
Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024 Ferreccio C.; Roa, Jc; Bambs C.; Vives, A; Corvalan, AH; Cortés S.; Foerster, C; Acevedo, J; Huidobro A.; Passi, A; Toro, P; Covacevich, Y; de la Cruz R.; Koshiol, J; Olivares M.; Miquel, JF; Cruz F.; Silva R.; Quest, AF; Kogan, MJ; Castro, PF; Lavandero S. Article ISI SCOPUS BMC PUBLIC HEALTH (2016)
The Gene Expression Status of the PI3K/AKT/mTOR Pathway in Gastric Cancer Tissues and Cell Lines Riquelme I.; Tapia O.; Espinoza, J.A; Leal P.; Buchegger, K; Sandoval A.; Bizama, C; Araya J.C.; Peek R.M.; Roa, J.C Article ISI SCOPUS PATHOLOGY & ONCOLOGY RESEARCH (2016)
The inflammatory inception of gallbladder cancer. Espinoza, J; Bizama, C; Garcia, P; Ferreccio, C; Javle, M; Miquel, J; Koshiol, J; Roa, JC Article ISI Review Corresponding Biochimica et Biophysica Acta (BBA) - Reviews on Cancer (2016)
Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis Pizarro M.; Solís N.; Quintero, P.; Barrera F.; cabrera, D; Rojas-de Santiago, P; Arab, JP; Padilla, O; Roa, Jc; Moshage, H; Wree, A; Inzaugarat E; Feldstein, AE; Fardella, CE; Baudrand R.; Riquelme A.; Arrese M. Article ISI SCOPUS Liver International (2015)
Calcium calmodulin dependent kinase kinase 2-a novel therapeutic target for gastric adenocarcinoma Subbannayya, Y; Syed, N; Barbhuiya, MA; Raja R.; Marimuthu A.; Sahasrabuddhe, N; Pinto, SM; Manda, SS; Renuse, S; Manju, HC; Zameer, MAL; Sharma J.; Brait M; Srikumar, K; Roa, Jc; Kumar, MV; Kumar, KVV; Prasad, TSK; Ramaswamy, G; Kumar, RV; Pandey, A; Gowda H.; Chatterjee, A. Article ISI SCOPUS Cancer Biology and Therapy (2015)
Effects of c-FLIPL knockdown in cervical uterine carcinoma cell lines [Efectos de la inhibición de C-Flipl en líneas celulares de Cáncer de cuello uterino] Ili C.G.; Brebi P.; Garcia P.; Leal P.; Lopez, J.; Tapia O.; Letelier P; Weber, H; Castillo J.; Roa, J.C Article SCOPUS International Journal of Morphology (2015)
Endoscopic submucosal dissection in early gastric cancer. Experience in 16 patients Donoso, A.; Sharp A.; Parra-Blanco, A; Roa, Jc; Bachler, JP; Crovari, F; Funke, R.; Pimentel, F; Ibanez, L; Guzman, S Article ISI REVISTA MEDICA DE CHILE (2015)
Gallbladder Cancer: expert consensus statement Aloia, TA; Jarufe, N; Javle, M; Maithel, SK; Roa, Jc; Adsay V.; Coimbra, FJF; Jarnagin, WR Article ISI SCOPUS HPB (2015)
Genome-wide DNA methylation analysis reveals estrogen-mediated epigenetic repression of metallothionein-1 gene cluster in breast cancer Jadhav, RR; Ye, ZQ; Huang, RL; Liu, J; Hsu, PY; Huang, YW; Rangel, LB; Lai, HC; Roa, Jc; Kirma, NB; Huang, THM; Jin, VX Article ISI SCOPUS Clinical Epigenetics (2015)
Global phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways Wu, XY; Zahari, MS; Ma, BY; Liu, R; Renuse, S; Sahasrabuddhe, NA; Chen L.; Chaerkady, R; Kim MS; Zhong, J; Jelinek, C; Barbhuiya, MA; Leal-Rojas, P; Yang Y.; Kashyap, MK; Marimuthu A.; Ling, M; Fackler, MJ; Merino, V; Zhang Z.; Zahnow, CA; Gabrielson, E; Stearns, V; Roa, Jc; Sukumar, S; Gill, PS; Pandey, A Article ISI SCOPUS Oncotarget (2015)
Heregulin Co-opts PR Transcriptional Action Via Stat3 Role As a Coregulator to Drive Cancer Growth Proietti, CJ; Izzo F.; Flaque, MCD; Russo, RC; Venturutti L.; Mercogliano, MF; De Martino, M; Pineda V.; Munoz S.; Guzman P.; Roa, Jc; Schillaci R.; Elizalde, PV Article ISI SCOPUS Molecular Endocrinology (2015)
Long non-coding RNAs in gastric cancer: mechanisms and potential applications Riquelme, Ismael; Ili, Carmen; Carlos Roa, Juan; Brebi, Priscilla Article ISI ONCOTARGET (2015)
Loss of Expression of Reprimo, a p53-induced Cell Cycle Arrest Gene, Correlates with Invasive Stage of Tumor Progression and p73 Expression in Gastric Cancer Saavedra, K; Valbuena J.; Olivares, W; Marchant, MJ.; Rodríguez A.; Torres-Estay, V; Carrasco-Avino, G; Guzman, L; Aguayo, F.; Roa, Jc; Corvalan, AH Article ISI SCOPUS PLOS ONE (2015)
Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer Subbannayya T.; Leal-Rojas, P; Barbhuiya, MA; Raja R.; Renuse, S; Sathe, G; Pinto, SM; Syed, N; Nanjappa, V; Patil, AH; Garcia P.; Sahasrabuddhe, NA; Nair, B; Guerrero-Preston, R; Navani S.; Tiwari, PK; Santosh, V; Sidransky D.; Prasad, TSK; Gowda H.; Roa, Jc; Pandey, A; Chatterjee, A. Article ISI SCOPUS BMC Cancer (2015)
Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy Riquelme I.; Saavedra, K; Espinoza, JA; Weber, H; Garcia P.; Nervi, B; Garrido M.; Corvalyn, AH; Roa, Jc; Bizama, C Article ISI SCOPUS Oncotarget (2015)
Quantitative phosphoproteomic analysis of IL-33-mediated signaling Pinto S.M.; Nirujogi R.S.; Rojas P.L.; Patil A.H.; Manda S.S.; Subbannayya, Y; Roa, J.C; Chatterjee, A.; Prasad T.S.K.; Pandey, A Article ISI SCOPUS PROTEOMICS (2015)
Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice Weber, H; Leal P.; Stein S; Kunkel H; Garcia P.; Bizama, C; Espinoza, JA; Riquelme I.; Nervi, B; Araya, JC; Grez, M; Roa, Jc Article ISI SCOPUS Oncotarget (2015)
Tumor Location Is a Strong Predictor of Tumor Progression and Survival in T2 Gallbladder Cancer An International Multicenter Study Shindoh, J; De Aretxabala X.; Aloia, TA; Roa, Jc; Roa, I; Zimmitti, G; Javle, M; Conrad C.; Maru, DM; Aoki, T; Vigano, L; Ribero, D; Kokudo N.; Capussotti, L; Vauthey, JN Article ISI ANNALS OF SURGERY (2015)
[Genotyping of human papillomavirus in women under 25 years old treated in the screening program for cervical cancer]. Melo, Angélica; Vásquez, Ana M; Andana, Alejandra; Matamala, Marcela; Pino, Tulio; Guzmán, Pablo; Hoffstetter, Rene; IIi, Carmen; Brebi, Priscilla; Roa, Juan C Article Revista chilena de infectologÃa : Ã³rgano oficial de la Sociedad Chilena de InfectologÃa (2014)
COMPLETE PATHOLOGICAL RESPONSE TO IMATINIB MESYLATE IN AN EXTRAINTESTINAL GASTROINTESTINAL STROMAL TUMOR Quezada N, Acevedo F, Marambio A, León F, Galindo H, Roa JC, Jarufe N Article ISI Int J Surg Case Rep. (2014)
EFFECTS OF c-FLIPL KNOCKDOWN IN CERVICAL UTERINE CARCINOMA CELL LINES Carmen G. Ili, Priscilla Brebi, Patricia Garcia, Pamela Leal, Jaime Lopez, Oscar Tapia, Pablo Letelier, Helga Weber, Juan C. Roa Article ISI VirchowsArch (2014)
Estimation of thyroid cancer incidence in Chile based on pathological reports Sapunar, J; Munoz S.; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2014)
Evaluation of ZAR1 and SFRP4 methylation status as potentials biomarkers for diagnosis in cervical cancer: exploratory study phase I Brebi P.; Hoffstetter R; Andana, A; Ili CG; Saavedra, K; Viscarra, T; Retamal J.; Sanchez R.; Roa, Jc Article ISI SCOPUS BIOMARKERS (2014)
Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population Brebi P.; Maldonado, L.; Noordhuis M.G.; Ili C.; Leal P.; Garcia P.; Brait M; Ribas, J; Michailidi C; Perez J.; Soudry E; Tapia O.; Guzman P.; Munoz S.; Van Neste L.; Van Criekinge W.; Irizarry R; Sidransky D.; Roa, J.C; Guerrero-Preston, R Article ISI SCOPUS EPIGENETICS (2014)
Genotyping of human papillomavirus in women under 25 years old treated in the screening program for cervical cancer Melo A.; Vasquez, AM; Andana, A; Matamala M.; Pino T.; Guzman P.; Hoffstetter R; Ili C.; Brebi P.; Roa, Jc Article ISI REVISTA CHILENA DE INFECTOLOGIA (2014)
Genotyping of human papillomavirus in women under 25 years old treated in the screening program for cervical cancer [Genotipificación del virus papiloma humano en mujeres bajo 25 años de edad participantes del Programa Nacional del Cáncer Cérvico-uterino en la Región de la Araucanía, Chile] Melo A.; Vásquez A.M.; Andana, A; Matamala M.; Pino T.; Guzman P.; Hoffstetter R; Ili C.; Brebi P.; Roa, J.C Article SCOPUS Revista Chilena de Infectologia (2014)
Hipermetilación del gen supresor de tumores p53 en pacientes pediátricos con leucemia linfoblástica aguda [Hypermethylation of tumor suppressor gene p53 in Chilean pediatrics patients under 15 years with acute lymphoblastic leukemia] Melo A.; Artigas C.G.; Fritz, C.; Díaz P; Munoz S.; Brebi P.; Roa, J.C Article SCOPUS International Journal of Morphology (2014)
Human Papilloma Virus Frequency in non-Gynecological Tumors in the Araucania Region, Chile Hoffstetter R; Andana, A; Guzman P.; Ili CG; Retamal J.; Mora B.; Roa, Jc; Sanchez R. Article ISI INTERNATIONAL JOURNAL OF MORPHOLOGY (2014)
Human papilloma virus frequency in non-gynecological tumors in the araucanía region, Chile [Frecuencia de virus papiloma humano en tumores no ginecológicos de la región de la araucanía, Chile] Hoffstetter R; Andana, A; Guzman P.; Ili C.G.; Retamal J.; Mora B.; Roa, J.C; Sanchez R. Article SCOPUS International Journal of Morphology (2014)
Hypermethylation of Tumor Suppressor Gene p53 in Chilean Pediatrics Patients Under 15 Years with Acute Lymphoblastic Leukemia Melo A.; Artigas, CG; Fritz, C.; Díaz P; Munoz S.; Brebi P.; Roa, Jc Article ISI INTERNATIONAL JOURNAL OF MORPHOLOGY (2014)
IDENTIFICATION OF PROSAPOSIN AND TRANSGELIN AS POTENTIAL BIOMARKERS FOR GALLBLADDER CANCER USING QUANTITATIVE PROTEOMICS Sahasrabuddhe NA, Barbhuiya MA, Bhunia S, Subbannayya T, Gowda H, Advani J, Shrivastav BR, Navani S, Leal P, Roa JC, Chaerkady R, Gupta S, Chatterjee A, Pandey A, Tiwari PK Article ISI VirchowsArch (2014)
IMMUNOHISTOCHEMICAL ANALYSIS OF THE PI3K/AKT/mTOR PATHWAY IN GASTRIC CANCER: CORRELATION WITH CLINICOPATHOLOGICAL FEATURES AND CUMULATIVE SURVIVAL. Tapia O, Riquelme I, Leal P, Sandoval A, Aedo S, Weber H, Letelier P, Bellolio E, Villaseca M, Garcia P, Roa JC Article VirchowsArch (2014)
Immunohistochemical Expression of Vascular Endothelial Growth Factor A in Advanced Gallbladder Carcinoma Roa, Juan C.; Buchegger, Kurt; Letelier, Pablo; Riquelme, Ismael; Leal, Pamela; sandoval, alejandra; García, Patricia; Tapia, Oscar; Ili, Carmen Article ISI APPLIED IMMUNOHISTOCHEMISTRY MOLECULAR MORPHOLOGY (2014)
IMMUNOHISTOCHEMICAL EXPRESSION OF VASCULAR ENDOTHELIAL GROWTH FACTOR A INADVANCED GALLBLADDER CARCINOMA Letelier P, Garcia P, Leal P, Ili C, Buchegger K, Riquelme I, Sandoval A, Tapia O, Roa JC Article ISI BIOMARKERS (2014)
MIR-1 AND MIR-145 ACT AS TUMOR SUPPRESSOR MICRORNAS IN GALLBLADDER CANCER Carmen G. Ili, Priscilla Brebi, Patricia Garcia, Pamela Leal, Jaime Lopez, Oscar Tapia, Pablo Letelier, Helga Weber, Juan C. Roa Article ISI VirchowsArch (2014)
SYNCHRONOUS ILEOCECALAND DUODENAL TUBERCULOSIS: CASE REPORT AND REVIEW OF THE LITERATURE Villalon C, Quezada F, Hartmann J, Roa JC, Urrejola G Article ISI Int J Colorectal Dis (2014)
TARGETING ERBB-2 NUCLEAR LOCALIZATION AND FUNCTION INHIBITS BREAST CANCER GROWTH AND OVERCOMES TRASTUZUMAB RESISTANCE Cordo Russo RI, Béguelin W, Díaz Flaqué MC, Proietti CJ, Venturutti L, Galigniana N, Tkach M, Guzmán P, Roa JC, O'Brien NA, Charreau EH, Schillaci R, Elizalde PV Article ISI ONCOGENE (2014)
The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance Oscar Tapia; Ismael Riquelme; Pamela Leal; Alejandra Sandoval; Susana Aedo; Helga Weber; Pablo Letelier; Enrique Bellolio; Miguel Villaseca; Patricia Garcia Article VIRCHOWS ARCHIV (2014)
The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance. Tapia, Oscar; Riquelme, Ismael; Leal, Pamela; Sandoval, Alejandra; Aedo, Susana; Weber, Helga; Letelier, Pablo; Bellolio, Enrique; Villaseca, Miguel; Garcia, Patricia; Roa, Juan Carlos Article Virchows Archiv : an international journal of pathology (2014)
TUMOR LOCATION IS A STRONG PREDICTOR OF TUMOR PROGRESSION AND SURVIVAL IN T2 GALLBLADDER CANCER: AN INTERNATIONAL MULTICENTER STUDY Shindoh J1, de Aretxabala X, Aloia TA, Roa JC, Roa I, Zimmitti G, Javle M, Conrad C, Maru DM, Aoki T, Vigano L, Ribero D, Kokudo N, Capussotti L,Vauthey JN Article ISI ANNALS OF SURGERY (2014)
AKT/mTOR substrate P70S6K is frequently phosphorylated in gallbladder cancer tissue and cell lines Leal P.; Garcia P.; Sandoval A.; Buchegger, K; Weber, H; Tapia O.; Roa, J.C Article ISI SCOPUS OncoTargets and Therapy (2013)
Cellular FLICE-like Inhibitory Protein Long Form (c-FLIPL) Overexpression is Related to Cervical Cancer Progression Ili CG; Brebi P.; Tapia O.; Sandoval A.; Lopez, J.; Garcia P.; Leal P.; Sidransky D.; Guerrero-Preston, R; Roa, Jc Article ISI SCOPUS International Journal of Gynecological Pathology (2013)
CMS: A Web-Based System for Visualization and Analysis of Genome-Wide Methylation Data of Human Cancers Gu, F; Doderer, MS; Huang, YW; Roa, Jc; Goodfellow, PJ; Kizer, EL; Huang, THM; Chen, YD Article ISI SCOPUS PLOS ONE (2013)
Connective Tissue Growth Factor Immunohistochemical Expression Is Associated With Gallbladder Cancer Progression Garcia P.; Leal P.; Alvarez H.; Brebi P.; Ili C.; Tapia O.; Roa, Jc Article ISI SCOPUS Archives of Pathology and Laboratory Medicine (2013)
Detection of human papilloma virus infection in men Silva R.; León D.; Brebi P.; Ili C.; Roa, Jc; Sanchez R. Article ISI REVISTA CHILENA DE INFECTOLOGIA (2013)
Detection of human papilloma virus infection in men [Diagnóstico de la infección por virus papiloma humano en el hombre] Silva R.; LeÃ³n D.; Brebi P.; Ili C.; Roa, J.C; SÃ¡nchez R. Article SCOPUS Revista Chilena de Infectologia (2013)
Detection of Hypermethylation in Tumor Suppressor Genes APAF1, ASSP1, p73 and FHIT in Childhood Acute Lymphoblastic Leukemia Melo A.; Artigas, CG; Munoz S.; Brebi P.; Hoffstetter R; Roa, Jc Article ISI INTERNATIONAL JOURNAL OF MORPHOLOGY (2013)
Early gallbladder carcinoma has a favorable outcome but Rokitansky-Aschoff sinus involvement is an adverse prognostic factor Roa, Jc; Tapia O.; Manterola C.; Villaseca M.; Guzman P.; Araya, JC; Bagci P.; Saka B.; Adsay V. Article ISI SCOPUS Virchows Archiv (2013)
Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas Jiao, YC; Pawlik, TM; Anders, RA; Selaru, FM; Streppel, MM; Lucas, DJ; Niknafs, N; Guthrie, VB; Maitra A.; Argani, P; Offerhaus, GJA; Roa, Jc; Roberts, LR; Gores, GJ; Popescu, I; Alexandrescu, ST; Dima, S; Fassan, M; Simbolo, M; Mafficini, A; Capelli, P; Lawlor, RT; Ruzzenente, A; Guglielmi A.; Tortora, G; De Braud, F; Scarpa A.; Jarnagin, W; Klimstra, D; Karchin, R; Velculescu, VE; Hruban, RH; Vogelstein, B; Kinzler, KW; Papadopoulos N.; Wood, LD Article ISI SCOPUS Nature Genetics (2013)
Frequency of Chlamydia trachomatis infection in a group of women from Region of Araucania, Chile Silva R.; León D.; Viscarra, T; Ili C.; Roa, Jc; Sanchez R.; Guzman P.; Brebi P. Article ISI REVISTA CHILENA DE INFECTOLOGIA (2013)
Growth Patterns of High-Grade Gallbladder Dysplasia: Clinicopathologic Associations and Diagnostic Implications in an Analysis of 318 Cases Bagci P.; Saka B.; Erbarut, I; Dursun N.; Basturk O.; Roa, Jc; Escalona, OT; Losada H.; Jang, KT; Kong, SY; Farris, AB; Adsay V. Article LABORATORY INVESTIGATION (2013)
Immunohistochemical Expression of Phospho-mTOR Is Associated With Poor Prognosis in Patients With Gallbladder Adenocarcinoma Leal P.; Garcia P.; Sandoval A.; Letelier P; Brebi P.; Ili C.; Alvarez H.; Tapia O.; Roa, Jc Article ISI SCOPUS Archives of Pathology and Laboratory Medicine (2013)
Inhibition of connective tissue growth factor (CTGF/CCN2) in gallbladder cancer cells leads to decreased growth in vitro Garcia P.; Leal P.; Ili C.; Brebi P.; Alvarez H.; Roa, Jc Article ISI SCOPUS International Journal of Experimental Pathology (2013)
International Consensus Study on the Terminology and Diagnosis of Tumoral Intraepithelial Neoplasms ("Adenomas" and "Intracystic Papillary Neoplasms" of WHO-2010) of the Gallbladder Adsay V.; Jang, KT; Ohike, N; Albores-Saavedra, J; Argani, P; Fukushima, N; Furukawa, T; Hruban, R; Kijima, H; Klimstra, D; Kloppel, G; Lauwers, G; Ochiai, A; Roa, Jc; Shimizu, M; Terris, B; Zamboni, G; Zen, Y; Tajiri, T; Basturk O.; Saka B.; Dursun N.; Bagci P.; Goodman, M. Article LABORATORY INVESTIGATION (2013)
Neoadjuvant chemoradiation therapy for borderline pancreatic adenocarcinoma: report of two cases Galindo, J; Gabrielli, M; Guerra, JF; Cassina, JC; Garrido M.; Jarufe, N; Borghero, Y; Madrid J.; Zoroquiain, P; Roa, Jc; Martinez, J. Article ISI SCOPUS World Journal of Surgical Oncology (2013)
Perfil de Metilación de Genes Supresores de Tumores APAF1, ASSP1, p73 y FHIT en Pacientes con Leucemia Linfoblástica Aguda Infantil Ang Melo A; Carmen Gloria Artigas A.; Sergio Mu; Priscilla Brebi M.; Rene Hoffstetter G; Juan Carlos Roa S. Article SCIELO SCOPUS INTERNATIONAL JOURNAL OF MORPHOLOGY (2013)
Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy Flaque, MCD; Galigniana, NM; Beguelin, W; Vicario, R; Proietti, CJ; Russo, RC; Rivas, MA; Tkach M.; Guzman P.; Roa, Jc; Maronna, E; Pineda V.; Munoz S.; Mercogliano, MF; Charreau, EH; Yankilevich P.; Schillaci R.; Elizalde, PV Article ISI SCOPUS Breast Cancer Research (2013)
PROGESTERONE RECEPTOR ASSEMBLY OF A TRANSCRIPTIONAL COMPLEX ALONG WITH AP-1, STAT3 AND ERBB-2 GOVERNS BREAST CANCER GROWTH AND PREDICTS RESPONSE TO ENDOCRINE THERAPY ”, Díaz Flaqué MC, Galigniana NM, Béguelin W, Vicario R, Proietti CJ, Russo RC, Rivas MA, Tkach M, Guzmán P, Roa JC, Maronna E, Pineda V, Muñoz S, MercoglianoMF, Charreau EH, Yankilevich P, Schillaci R, Elizalde PV Article ISI Breast Cancer Res (2013)
SILAC-based quantitative proteomic analysis of gastric cancer secretome Marimuthu A.; Subbannayya, Y; Sahasrabuddhe, NA; Balakrishnan, L; Syed, N; Sekhar, NR; Katte, TV; Pinto, SM; Srikanth, SM; Kumar, P; Pawar, H; Kashyap, MK; Maharudraiah J.; Ashktorab, H; Smoot, DT; Ramaswamy, G; Kumar, RV; Cheng, YL; Meltzer SJ; Roa, Jc; Chaerkady, R; Prasad, TSK; Harsha, HC; Chatterjee, A.; Pandey, A Article ISI SCOPUS Proteomics - Clinical Applications (2013)
Treatment of the residual cavity during hepatic hydatidosis surgery: a cohort study of capitonnage vs. omentoplasty Manterola C.; Roa, Jc; Urrutia, S Article ISI SCOPUS Surgery Today (2013)
VIRULENCE OF INFECTING HELICOBACTER PYLORI STRAINS AND AMOUNT OF MONONUCLEAR CELL INFILTRATION ARE ASSOCIATED WITH LEVELS OF DNA HYPERMETHYLATION IN GASTRIC MUCOSAE Schneider BG, Piazuelo MB, Sicinschi LA, Mera R, Peng DF, Roa JC, Romero-Gallo J, Delgado AG, de Sablet T, Bravo LE, Wilson KT, El-Rifai W, Peek RM Jr, Correa P Article ISI EPIGENETICS (2013)
Virulence of infecting Helicobacter pylori strains and intensity of mononuclear cell infiltration are associated with levels of DNA hypermethylation in gastric mucosae Schneider, BG; Piazuelo, MB; Sicinschi, LA; Mera R.; Peng, DF; Roa, Jc; Romero-Gallo, J; Delgado, AG; de Sablet, T; Bravo, LE; Wilson, KT; El-Rifai, W; Peek, RM; Correa P. Article ISI SCOPUS Epigenetics (2013)
Clinical and public health research using methylated DNA immunoprecipitation (MeDIP) A comparison of commercially available kits to examine differential DNA methylation across the genome Brebi-Mieville, P; Ili-Gangas, C; Leal-Rojas, P; Noordhuis M.G.; Soudry E; Perez J.; Roa C.J.; Sidransky D.; Guerrero-Preston, R Article ISI SCOPUS Epigenetics (2012)
Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer Schillaci R.; Guzman P.; Cayrol F.; Beguelin, W; Díaz Flaqué M.C.; Proietti C.J.; Pineda V.; Palazzi J.; Frahm I.; Charreau E.H.; Maronna, E; Roa, J.C; Elizalde P.V. Article ISI SCOPUS BMC Cancer (2012)
DNA PROMOTER METHYLATION AS A DIAGNOSTIC AND THERAPEUTIC BIOMARKER IN GALLBLADDER CANCER Letelier P, Brebi P, Tapia O, Roa JC. Article ISI Clinical Epigenetics (2012)
EPIGENETIC ALTERATIONS IN PRENEOPLASTIC AND NEOPLASTIC LESIONS OF UTERINE CERVIX Kathleen Saavedra P, Priscilla Brebi M, and Juan Carlos Roa S Article ISI Clinical Epigenetics (2012)
Gallbladder Pathology in IgG4-Related Sclerosing Disease Bagci P.; Saka B.; Dursun N.; Basturk O.; Bandyopadhyay, S; Jang, KT; Kong, SY; Goodman, M.; Farris, AB; Krasinskas, A; Zen, Y; Tapia, OE; Roa, Jc; Adsay V. Article LABORATORY INVESTIGATION (2012)
High Grade Dysplasia (Intraepithelial Neoplasia) of the Gallbladder (GB): Patterns, Cell Lineages and Clinicopathologic Associations in an Analysis of 255 Cases Bagci P.; Dursun N.; Saka B.; Basturk O.; Roa, Jc; Tapia O.; Jang, KT; Erbarut, I; Kong, SY; Cheng, J; Adsay V. Article LABORATORY INVESTIGATION (2012)
Intracholecystic Papillary-Tubular Neoplasms (ICPN) of the Gallbladder (Neoplastic Polyps, Adenomas, and Papillary Neoplasms That Are >= 1.0 cm) Clinicopathologic and Immunohistochemical Analysis of 123 Cases Adsay V.; Jang K.-T.; Roa, J.C; Escalona O.T.; Dursun N.; Ohike, N; Bagci P.; Basturk O.; Bandyopadhyay, S; Cheng J.D.; Sarmiento, J.M.; Goodman, M.; Kong S.Y.; Terry, P Article ISI SCOPUS American Journal of Surgical Pathology (2012)
Mucinous Carcinomas of the Gallbladder Clinicopathologic Analysis of 15 Cases Identified in 606 Carcinomas Dursun N.; Escalona O.T.; Roa, J.C; Basturk O.; Bagci P.; Cakir, A.; Cheng, J; Sarmiento J.; Losada H.; Kong S.Y.; Ducato, L; Goodman, M.; Volkan Adsay N. Article ISI SCOPUS Archives of Pathology and Laboratory Medicine (2012)
Overexpression of kinesin associated protein 3 (KIFAP3) in breast cancer Telikicherla D.; Maharudraiah J.; Pawar, H; Marimuthu A.; Kashyap M.K.; Ramachandra Y.L.; Roa, J.C; Pandey, A Article SCOPUS Journal of Proteomics and Bioinformatics (2012)
Overexpression of ribosome binding protein 1 (RRBP1) in breast cancer Telikicherla D.; Marimuthu A.; Kashyap M.K.; Ramachandra Y.L.; Mohan S.; Roa, J.C; Maharudraiah J.; Pandey, A Article SCOPUS Clinical Proteomics (2012)
Pathologic staging of pancreatic, ampullary, biliary, and gallbladder cancers: pitfalls and practical limitations of the current AJCC/UICC TNM staging system and opportunities for improvement Adsay N.V.; Bagci P.; Tajiri, T; Oliva I.; Ohike, N; Balci, S; Gonzalez R.S.; Basturk O.; Jang K.-T.; Roa, J.C Article ISI SCOPUS Seminars in Diagnostic Pathology (2012)
Carcinoma epidermoide oral y orofaríngeo: Estudio clínico-patológico GUZMÁN G, PABLO; Villaseca H, Miguel; Antonio P, Lilia; Araya O, Juan; Aravena M, Paola; Cravero P, Carla; Pino M, Pilar; Roa S, Juan Article SCIELO REVISTA CHILENA DE CIRUGIA (2011)
Compromiso ganglionar extracapsular en pacientes con cáncer gástrico: determinación del valor pronóstico Tapia E, Oscar; Villaseca H, Miguel; ARAYA O, JUAN CARLOS; Roa S, Juan Carlos Article SCIELO SCOPUS REVISTA MEDICA DE CHILE (2011)
Concordance between Gleason scores of trans rectal biopsies and the surgical piece of radical prostatectomy Tapia O.; Bellolio E.; Roa, Jc; Guzman P.; Villaseca M.; Araya, JC Article ISI REVISTA MEDICA DE CHILE (2011)
Cáncer gástrico sin compromiso ganglionar linfático (pN0): características demográfico-patológicas y factores pronósticos Tapia E, Oscar; Villaseca H, Miguel; Bellolio J, Enrique; ARAYA O, JUAN CARLOS; Roa S, Juan Carlos Article SCIELO SCOPUS REVISTA MEDICA DE CHILE (2011)
Diverticular disease of the appendix in appendectomies Munoz, C; Mansilla, J; Roa, Jc; Heider, C. Article ISI REVISTA CHILENA DE CIRUGIA (2011)
Factores asociados al pronóstico de pacientes operados por cáncer gástrico avanzado Tapia E, Oscar; Roa S, Juan Carlos; Manterola D, Carlos; PUGA A, VALENTINA; Villaseca H, Miguel; ARAYA O, JUAN CARLOS Article SCIELO REVISTA CHILENA DE CIRUGIA (2011)
Factores morfológicos asociados al pronóstico de pacientes operados por cáncer gástrico incipiente Tapia E, Oscar; GARCÍA M, PATRICIA; Manterola D, Carlos; Villaseca H, Miguel; ARAYA O, JUAN CARLOS; Roa S, Juan Carlos Article SCIELO REVISTA CHILENA DE CIRUGIA (2011)
Gallbladder carcinosarcoma. Case report Tapia O.; Roa, Jc; Antonio L. Article ISI REVISTA CHILENA DE CIRUGIA (2011)
Gene Expression Profiling of Gastric Cancer Marimuthu A.; Harrys, J; Jakharia, A; Subbannayya, Y; Keerthikumar, S; Kumar, M; Goel, R; Balakrishnan, L; Dwivedi S.; Pathare, S; Bajpai, J; Maharudraiah J.; Sujay, S; Sameer, G; Vijakumar, M; Veeraiah, K; Chennagiri, S; Pramila, T,; Ramesh, K. H.; Roa, J.C; Prasad, T. S.; Chaerkady, R; Kumar, R; Pandey, A Article SCOPUS Journal of Proteomics and Bioinformatics (2011)
Genotyping of Human Papillomavirus in Cervical Intraepithelial Neoplasia in a High-Risk Population Ili CG; Brebi P.; Lopez, J.; Garcia P.; Leal P.; Suarez, E; Roa, Jc Article ISI SCOPUS Journal of Medical Virology (2011)
Hyalinizing Cholecystitis and Associated Carcinomas: Clinicopathologic Analysis of a Distinctive Variant of Cholecystitis With Porcelain-like Features and Accompanying Diagnostically Challenging Carcinomas Patel, S; Roa, Jc; Tapia O.; Dursun N.; Bagci P.; Basturk O.; Cakir, A.; Losada H.; Sarmiento J.; Adsay V. Article ISI SCOPUS American Journal of Surgical Pathology (2011)
Los Pericitos: Nuevos Enfoques en la Terapia Regenerativa, Patología Cerebrovascular y Cáncer Montiel-Eulefi, Enrique; Barrientos Díaz, Leticia; Leal, Pamela; Roa, Juan Carlos; Risopatrón, Jennie; Salazar, Luis A.; Romero, Fernando; Sánchez, Raúl Article International Journal of Morphology (2011)
Oral and oropharingeal squamous cells carcinoma. Clinico-pathological study Guzman P.; Villaseca M.; Antonio L.; Araya J.; Aravena P.; Cravero, C; Pino, P; Roa, J Article ISI REVISTA CHILENA DE CIRUGIA (2011)
Pathological factors associated with survival in advanced gastric cancer Tapia O.; Roa, Jc; Manterola C.; Puga, V; Villaseca M.; Araya, JC Article REVISTA CHILENA DE CIRUGIA (2011)
Pathological features associated with survival in early gastric cancer Tapia O.; Garcia P.; Manterola C.; Villaseca M.; Araya, JC; Roa, Jc Article ISI REVISTA CHILENA DE CIRUGIA (2011)
Pericytes: New Approaches in Regenerative Therapy, Cerebrovascular Pathology and Cancer Montiel-Eulefi, E; Diaz, LB; Leal P.; Roa, Jc; Risopatrón J.; SALAZAR, LA; Romero F.; Sanchez R. Article ISI INTERNATIONAL JOURNAL OF MORPHOLOGY (2011)
Prevalencia de enfermedad diverticular del apéndice cecal en pacientes apendicectomizados por apendicitis aguda Muñoz C, César; MANSILLA E, JUAN; Roa S, Juan Carlos; Heider C, Claudia Article SCIELO REVISTA CHILENA DE CIRUGIA (2011)
Prognostic factors for gastric cancer without lymph node involvement Tapia O.; Villaseca M.; Bellolio E.; Araya, JC; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2011)
Prognostic value of extracapsular lymph node involvement among patients with gastric cancer Tapia O.; Villaseca M.; Araya, JC; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2011)
Puntaje de Gleason en cáncer de próstata: Correlación de la biopsia por punción y prostatectomía radical Tapia E, Oscar; Bellolio J, Enrique; Roa S, Juan Carlos; GUZMÁN G, PABLO; Villaseca H, Miguel; ARAYA O, JUAN CARLOS Article SCIELO SCOPUS REVISTA MEDICA DE CHILE (2011)
Soluble A beta(1-40) Peptide Increases Excitatory Neurotransmission and Induces Epileptiform Activity in Hippocampal Neurons Cuevas ME; Haensgen, H; Sepulveda, FJ; Zegers G.; Roa, J; Opazo C.; Aguayo, LG Article ISI SCOPUS Journal of Alzheimer's Disease (2011)
Squamous cell and adenosquamous carcinomas of the gallbladder: clinicopathological analysis of 34 cases identified in 606 carcinomas Roa, Jc; Tapia O.; Cakir, A.; Basturk O.; Dursun N.; Akdemir, D; Saka B.; Losada H.; Bagci P.; Adsay, NV Article ISI SCOPUS Modern Pathology (2011)
Tumores del Estroma Gastrointestinal (GIST): Características Clinico-Morfológicas y Perfil Inmunohistoquímico Tapia E, Oscar; Roa S, Juan Carlos Article SCIELO INTERNATIONAL JOURNAL OF MORPHOLOGY (2011)
Widespread Hypomethylation Occurs Early and Synergizes with Gene Amplification during Esophageal Carcinogenesis Alvarez H.; Montgomery E.A.; Maitra A.; Opalinska J.; Zhou, L; Sohal D.; Yu, Y; Montagna, C; Mo Y.; Bhagat T.; Cannizzaro L.; Thompson R.F.; Suzuki, M; Greally J.M.; Verma, A; Fazzari M.J.; Canto, M; Dunbar K.B.; Wang J.; Meltzer, S; Roa, J.C; Ramesh, K. H.; Mollenhauer J.; Melnick A. Article ISI SCOPUS PLoS Genetics (2011)
Bone hydatidosis. Report of five patients Tapia O.; Vidal, A; Bellolio E.; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2010)
Breast hydatidosis. Report of one case Tapia O.; Pineda V.; Roa, Jc Article ISI REVISTA CHILENA DE CIRUGIA (2010)
Carcinoma de células en anillo de sello gástrico: Descripción clínico-morfológica y valor pronóstico Tapia E, Oscar; GUTIÉRREZ M, VALENTINA; Roa S, Juan Carlos; Manterola D, Carlos; Villaseca H, Miguel; ARAYA O, JUAN CARLOS Article SCIELO REVISTA CHILENA DE CIRUGIA (2010)
Changes in morphological an clinical characteristics of gastric cancer from 1986 to 2005 Tapia O.; Roa, Jc; Manterola C.; Villaseca M.; Gutierrez V.; Flores P.; Araya, JC; Guzman P. Article ISI REVISTA CHILENA DE CIRUGIA (2010)
Colon and Rectum Cancer: Morphological and Clinical Description of 322 Cases Tapia O.; Roa, Jc; Manterola C.; Bellolio E. Article ISI INTERNATIONAL JOURNAL OF MORPHOLOGY (2010)
Cáncer de Colon y Recto: Descripción Morfológica y Clínica de 322 Casos Tapia E, Oscar; Roa S, Juan Carlos; Manterola D, Carlos; Bellolio J, Enrique Article SCIELO INTERNATIONAL JOURNAL OF MORPHOLOGY (2010)
Cáncer gástrico en una región de Chile: Comparación de variables clínicas y morfológicas en dos períodos (1986-1995 y 1996-2005) Tapia E, Oscar; Roa S, Juan Carlos; Manterola D, Carlos; Villaseca H, Miguel; GUTIÉRREZ M, VALENTINA; FLORES O, PLÁCIDO; ARAYA O, JUAN CARLOS; GUZMÁN G, PABLO Article SCIELO REVISTA CHILENA DE CIRUGIA (2010)
Descripción clínico-morfológica y factores pronósticos en carcinomas de apéndice cecal: Estudio de cohorte Tapia E, Oscar; Manterola D, Carlos; Villaseca H, Miguel; ARAYA O, JUAN CARLOS; GUZMÁN G, PABLO; Roa S, Juan Carlos Article SCIELO REVISTA CHILENA DE CIRUGIA (2010)
Detección y tipificación de virus papiloma humano en lesiones preneoplásicas de cuello uterino LÓPEZ M, JAIME; Ili G, Carmen Gloria; Brebi M, Priscilla; GARCÍA M, PATRICIA; CAPURRO V, ITALO; GUZMÁN G, PABLO; SUÁREZ P, EUGENIO; OJEDA F, JOSÉ MANUEL; Roa S, Juan Carlos Article SCIELO REVISTA MEDICA DE CHILE (2010)
Duodenal villous atrophy associated with Mycophenolate mofetil. Report of one case Tapia O.; Villaseca M.; Sierralta A.; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2010)
Evaluación de factores histológicos pronósticos de sobrevida en melanoma maligno cutáneo, seguimiento de 13 años Bellolio J, Enrique; SAN MARTÍN L, ALVARO; Quiñiñir S, Luis; Orellana C, Juan; Tapia E, Oscar; RIFO L, PATRICIO; Roa S, Juan Carlos; Villaseca H, Miguel Article SCIELO REVISTA CHILENA DE CIRUGIA (2010)
Genotipificación del virus papiloma humano en mujeres con adenocarcinoma cervical de la Región de La Araucanía-Chile Melo A, Angélica; GARCÍA M, PATRICIA; CAPURRO V, ITALO; GUZMÁN G, PABLO; Brebi M, Priscila; Ili G, Carmen; LÓPEZ M, JAIME; Roa S, Juan C Article SCIELO REVISTA CHILENA DE INFECTOLOGIA (2010)
Hallazgos morfológicos en casos fatales de síndrome cardiopulmonar por hantavirus: Estudio de 7 autopsias GUZMÁN G, PABLO; Tapia E, Oscar; Villaseca H, Miguel; Araya O, Juan; Antonio P, Lilia; Lee O, Bolívar; Roa S, Juan Article SCIELO REVISTA CHILENA DE INFECTOLOGIA (2010)
Human papillomavirus genotyping in cervical adenocarcinoma in the Region of La Araucania-Chile Melo A.; Garcia P.; Capurro I; Guzman, G; Brebi P.; Ili C.; Lopez, J.; Roa, Jc Article ISI REVISTA CHILENA DE INFECTOLOGIA (2010)
Human papillomavirus genotyping of cervical uterine preneoplastic lesions in a high risk area Lopez, J.; Ili CG; Brebi P.; Garcia P.; Capurro I; Guzman P.; Suarez, E; Ojeda, JM; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2010)
Morphological findings in fatal cases of hantavirus cardiopulmonary syndrome. Report of 7 autopsies Guzman P.; Tapia O.; Villaseca M.; Araya J.; Antonio L.; Lee, B; Roa, J Article ISI REVISTA CHILENA DE INFECTOLOGIA (2010)
Prognosis of signet ring cell carcinoma of the stomach Tapia O.; Gutierrez V.; Roa, Jc; Manterola C.; Villaseca M.; Araya, JC Article ISI REVISTA CHILENA DE CIRUGIA (2010)
Prognostic factors for survival of malignant melanomas Bellolio E.; San Martin, A; Quininir, L; Orellana J.; Tapia O.; Rifo, P; Roa, Jc; Villaseca M. Article ISI REVISTA CHILENA DE CIRUGIA (2010)
Survival of a cohort of patients with Intermediate and advanced gall bladder cancer treated with a prospective therapeutic protocol Manterola C.; Vial, M; Roa, Jc Article ISI SCOPUS Acta Cirurgica Brasileira (2010)
The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma Alvarez H.; Montgomery, EA; Karikari, C; Canto, M; Dunbar, KB; Wang, JS; Feldmann, G; Hong, SM; Haffner, MC; Meeker, AK; Holland, SJ; Yu, JX; Heckrodt, TJ; Zhang J.; Ding, PY; Goff, D; Singh R.; Roa, Jc; Marimuthu A.; Riggins, GJ; Eshleman, JR; Nelkin, BD; Pandey, A; Maitra A. Article ISI SCOPUS Cancer Biology and Therapy (2010)
Concomitant presence of a gastric adenocarcinoma and gastrointestinal stromal tumor. Report of one case Antonio L.; Guzman P.; Villaseca M.; Araya J.; De Toro, G; Roa, J Article ISI REVISTA MEDICA DE CHILE (2009)
Detección y tipificación de virus papiloma humano en adenocarcinoma de cuello uterino mediante reverse line blot, Región de La Araucanía, Chile Brebi M, Priscilla; Ili G, Carmen Gloria; LÓPEZ M, JAIME; GARCÍA M, PATRICIA; Melo A, Angélica; Montenegro H, Sonia; Leal R, Pamela; GUZMÁN G, PABLO; Roa S, Juan Carlos Article SCIELO REVISTA MEDICA DE CHILE (2009)
Detection and genotyping of human papillomavirus in biopsies of uterine cervical adenocarcinoma Brebi P.; Ili CG; Lopez, J.; Garcia P.; Melo A.; Montenegro, S; Leal P.; Guzman P.; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2009)
Diagnostic value of frozen section biopsy during surgery for breast lesions or neoplasms Bellolio E.; Guzman P.; Orellana J.; Roa, Jc; Villaseca M.; Araya, JC; Tapia O.; Pineda V. Article ISI REVISTA MEDICA DE CHILE (2009)
Early Gallbladder Cancer: Is Further Treatment Necessary? De Aretxabala X.; Roa, I; Hepp, J; Maluenda F; Mordojovich, G; León J.; Roa, Jc Article ISI SCOPUS JOURNAL OF SURGICAL ONCOLOGY (2009)
HPV genotyping from invasive cervical cancer in Chile Roa, Jc; Garcia P.; Gómez J.; Fernandez, W; Gaete, F; Espinoza, A.; Lepetic, A; Suarez, E Article ISI SCOPUS INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2009)
Promoter Hypermethylation gene patterns in gynecological tumors Leal Rojas, Pamela; Anabalón Rodríguez, Leonardo; García Muñoz, Patricia; Tapia Escalona, Oscar; Guzmán González, Pablo; Araya Orostica, Juan Carlos; Villaseca Hernández, Miguel Article Med Clin (Barc) (2009)
Promoter Methylation Profile in Preneoplastic and Neoplastic Gallbladder Lesions Garcia P.; Manterola C.; Araya, JC; Villaseca M.; Guzman P.; Sanhueza, A; Thomas, M; Alvarez H.; Roa, Jc Article ISI SCOPUS MOLECULAR CARCINOGENESIS (2009)
Description of Echinococcus granulosus genotypes in human hydatidosis in a region of southern Chile Manterola C.; Benavente F; Melo A.; Vial, M; Roa, Jc Article ISI SCOPUS PARASITOLOGY INTERNATIONAL (2008)
Estudio de patrones de metilación génica en tumores del tubo digestivo Roa S, Juan Carlos; GARCÍA M, PATRICIA; Melo A, Angélica; Tapia E, Oscar; Villaseca H, Miguel; ARAYA O, JUAN CARLOS; GUZMÁN G, PABLO Article SCIELO REVISTA MEDICA DE CHILE (2008)
Gene methylation patterns in digestive tumors Roa, Jc; Garcia P.; Melo A.; Tapia O.; Villaseca M.; Araya, JC; Guzman P. Article ISI REVISTA MEDICA DE CHILE (2008)
Papillary carcinoma in a thyroglossal duct cyst. Report of two cases Guzman P.; Baeza A.; Cabello, A.; Montecinos, A; Leal C.; Roa, J Article ISI REVISTA MEDICA DE CHILE (2008)
Prevalence of human papillomavirus genital infection among male university students Guzman P.; Ili C.; Rifo, P; Bricenno, G; Araya J.; Villaseca M.; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2008)
Prevalence of human papillomavirus genital infection among male university students Prevalencia de la infección genital por virus papiloma humano en hombres universitarios voluntarios de la IX Región, Chile Guzman P.; Ili C.; Araya J.; Villaseca M.; Roa, J.C; Rifo, P; Briceño G. Article REVISTA MEDICA DE CHILE (2008)
Prevalencia de la infección genital por virus papiloma humano en hombres universitarios voluntarios de la IX Región, Chile Guzmán, Pablo; Ili, Carmen; Rifo, Patricio; Briceño, Gastón; Araya, Juan; Villaseca, Miguel; Roa, Juan Carlos Article SCIELO REVISTA MEDICA DE CHILE (2008)
Serial analysis of gene expression identifies connective tissue growth factor expression as a prognostic biomarker in gallbladder cancer Alvarez H.; Corvalan, A; Roa, Jc; Argani, P; Murillo F.; Edwards J.; Beaty, R; Feldmann, G; Hong, SM; Mullendore, M; Roa, I; Ibanez, L; Pimente, F; Diaz A.; Riggins, GJ; Maitra A. Article ISI SCOPUS CLINICAL CANCER RESEARCH (2008)
Detección y tipificación de virus papiloma humano en lesiones preneoplásicas del cuello uterino mediante PCR-RFLP Aedo A, Susana; Melo A, Angélica; García, Patricia; GUZMÁN G, PABLO; CAPURRO V, ITALO; Roa S, Juan Carlos Article SCIELO REVISTA MEDICA DE CHILE (2007)
Detection and typification of human papilloma virus in pre cancerous cervical lesions Aedo S.; Melo A.; Garcia P.; Guzman P.; Capurro I; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2007)
Hepatocarcinoma with sarcomatoid transformation. Case report Losada, HM; Roa, Jc; Garcia, DM; Araya, JC; Burgos, LSJ; Silva, JA Article ISI REVISTA MEDICA DE CHILE (2007)
Hepatocarcinoma with sarcomatoid transformation. Case report Hepatocarcinoma con componente sarcomatoide. Caso clínico Losada M H.; Burgos SJ L.; Silva A J.; Garcia M.-D.; Roa, J.C; Araya J.C. Article REVISTA MEDICA DE CHILE (2007)
Inestabilidad microsatelital en lesiones preneoplásicas y neoplásicas del cuello uterino: Correlación con el genotipo del virus papiloma humano Roa S, Juan Carlos; Martínez S, Ricardo; Montenegro, Sonia; ROA E, IVÁN; CAPURRO V, ITALO; IBACACHE S, GILDA; Melo A, Angélica Article SCIELO REVISTA MEDICA DE CHILE (2007)
Microsatellite instability and human papilloma virus genotypes in preneoplastic and neoplastic uterine cervix lesions Roa, Jc; Martínez R.; Montenegro, S; Roa, I; Capurro I; Ibacache, G; Melo A. Article ISI REVISTA MEDICA DE CHILE (2007)
Chemoradiotherapy in gallbladder cancer De Aretxabala X.; Roa, I; Berríos M; Hepp, J; Gallardo J.; Cordova A.; Roa, Jc; León J.; Maluenda F Article ISI JOURNAL OF SURGICAL ONCOLOGY (2006)
Expresión inmunohistoquímica del complejo E-caderina-catenina en cáncer gástrico: Relación con variables clínico-morfológicas y sobrevida de pacientes GUZMÁN G, PABLO; Araya O, Juan; Villaseca H, Miguel; ROA E, IVÁN; Melo A, Angélica; Muñoz N, Sergio; Roa S, Juan Article REVISTA MEDICA DE CHILE (2006)
Frecuencia de los genes de fusión TEL/AML1 y BCR/ABL en pacientes pediátricos con leucemia linfoblástica aguda Artigas A, Carmen Gloria; Cabrera C, María Elena; Melo A, Angélica; Páez F, Eduardo; Arriagada M, Mónica; Astete A, Carmen; ROA E, IVÁN; Roa S, Juan Carlos Article REVISTA MEDICA DE CHILE (2006)
Frequency of TEL/AML1 and BCR/ABL fusion genes in children with acute lymphoblastic leukemia Artigas, CG; Cabrera, ME.; Melo A.; Paez E.; Arriagada M.; Astete, C; Roa, I; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2006)
Gallbladder cancer: An analysis of a series of 139 patients with invasion restricted to the subserosal layer De Aretxabala X.; Roa, I; Burgos, L.; Losada H.; Roa, Jc; Mora J.; Hepp, J; León J.; Maluenda F Article ISI SCOPUS JOURNAL OF GASTROINTESTINAL SURGERY (2006)
Gallstones and gallbladder cancer-volume and weight of gallstones are associated with gallbladder cancer: A case-control study Roa, I; Ibacache, G; Roa, J; Araya J.; De Aretxabala X.; Munoz S. Article ISI JOURNAL OF SURGICAL ONCOLOGY (2006)
Genetic methylation in carcinogenesis and its application in clinical oncology Metilación génica en la carcinogénesis y su aplicación en oncología clínica Roa, J.C Article MEDICINA CLINICA (2006)
Immunohistochemical expression of the E-cadherin-catenin complex in gastric cancer Guzman P.; Araya J.; Villaseca M.; Roa, I; Melo A.; Munoz S.; Roa, J Article ISI REVISTA MEDICA DE CHILE (2006)
Malignant melanoma in Chile: an unusual distribution of primary sites in men from low socioeconomic strata Zemelman, V; Roa, J; Tagle, SR; VALENZUELA, CY Article ISI CLINICAL AND EXPERIMENTAL DERMATOLOGY (2006)
Preneoplastic lesions in gallbladder cancer Roa, I; De Aretxabala X.; Araya, JC; Roa, J Article ISI JOURNAL OF SURGICAL ONCOLOGY (2006)
Prognostic factors of phyllodes tumor of the breast Roa, Jc; Tapia O.; Carrasco, P; Contreras, E; Araya, JC; Munoz S.; Roa, I Article ISI SCOPUS PATHOLOGY INTERNATIONAL (2006)
Promoter methylation profile in gallbladder cancer Roa, Jc; Anabalon, L; Roa, I; Melo A.; Araya, JC; Tapia O.; De Aretxabala X.; Munoz S.; Schneider, B Article ISI SCOPUS JOURNAL OF GASTROENTEROLOGY (2006)
Aneurysmal bone cyst of the maxilla. Report of one case Guzman P.; Baeza A.; Araya J.; Roa, J; Brevis, L; Torres P. Article ISI REVISTA MEDICA DE CHILE (2005)
Detection of human papilloma virus in cytologic samples or biopsies of the cervix Melo A.; Roa, I; Montenegro, S; Capurro I; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2005)
Estudio del patrón de metilación génico en el cáncer gástrico en Chile Roa S, Juan Carlos; Anabalón R, Leonardo; ROA E, IVÁN; Tapia E, Oscar; Melo, Angelica; Villaseca H, Miguel; ARAYA O, JUAN CARLOS Article REVISTA MEDICA DE CHILE (2005)
Frequency of K-ras mutation in biliary and pancreatic tumors Roa, Jc; Anabalon, L; Tapia O.; Melo A.; De Aretxabala X.; Roa, I Article ISI REVISTA MEDICA DE CHILE (2005)
Microsatellite instability in preneoplastic and neoplastic lesions of the gallbladder Roa, Jc; Roa, I; Correa P.; Vo, Q; Araya, JC; Villaseca M.; Guzman P.; Schneider, BG Article ISI SCOPUS JOURNAL OF GASTROENTEROLOGY (2005)
Mutación del gen K-ras en tumores pancreático-biliares Roa S, Juan Carlos; Anabalón R, Leonardo; Tapia E, Oscar; Melo A, Angélica; DE ARETXABALA U, XABIER; ROA E, IVÁN Article REVISTA MEDICA DE CHILE (2005)
Promoter methylation profile in gastric cancer Roa, Jc; Anabalon, L; Roa, I; Tapia O.; Melo A.; Villaseca M.; Araya, JC Article ISI REVISTA MEDICA DE CHILE (2005)
Quiste aneurismático del maxilar superior: Reporte de un caso GUZMÁN G, PABLO; Baeza O, Aníbal; Araya O, Juan; Roa S, Juan; Brevis O, Loreto; Torres L, Priscila Article REVISTA MEDICA DE CHILE (2005)
Association between Helicobacter pylori genotype and the severity of gastritis in infected adults Araya, JC; Anabalon, L; Roa, I; Bravo M.; Villaseca, MA; Guzman P.; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2004)
Clinicopathological features of gallbladder polyps and adenomas Roa, I; De Aretxabala X.; Morgan, R.; Molina, R.; Araya, JC; Roa, J; Ibacahe, G Article ISI REVISTA MEDICA DE CHILE (2004)
Detection of bone marrow micrometastases in patients with gallbladder cancer Roa, Jc; De Aretxabala X.; Melo A.; Faria G.; Araya, JC; Villaseca, MA; Guzman P.; Roa, I Article ISI REVISTA MEDICA DE CHILE (2004)
DNA content and survival in subserous gallbladder carcinoma Roa, I; De Aretxabala X.; Fuentealba P.; Cabrera, ME.; Araya, JC; Roa, J Article ISI REVISTA MEDICA DE CHILE (2004)
Inactivación del gen CDKN2A (p16) en cáncer de la vesícula biliar Roa S, Juan Carlos; Vo, Quynh; ARAYA O, JUAN CARLOS; Villaseca H, Miguel; GUZMÁN G, PABLO; IBACACHE S, GILDA; DE ARETXABALA U, XABIER; ROA E, IVÁN Article REVISTA MEDICA DE CHILE (2004)
Inactivation of CDKN2A gene (p16) in gallbladder carcinoma Roa, Jc; Vo, Q; Araya, JC; Villaseca M.; Guzman P.; Ibacache, G; De Aretxabala X.; Roa, I Article ISI REVISTA MEDICA DE CHILE (2004)
K-ras gene mutation in gallbladder carcinoma Roa, Jc; Roa, I; De Aretxabala X.; Melo A.; Faria G.; Tapia O. Article ISI REVISTA MEDICA DE CHILE (2004)
Management of gallbladder cancer with invasion of the muscular layer De Aretxabala X.; Roa, I; Mora J.; Pincheira, O; Burgos, L.; Silva J.; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2004)
Neoadjuvant chemoradiotherapy in gallbladder cancer De Aretxabala X.; Losada H.; Mora J.; Roa, I; Burgos, L.; Yáñez E.; Quijada, I; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2004)
Patrón de metilación génico en el cáncer de mama Roa S, Juan Carlos; Anabalón R, Leonardo; Tapia E, Oscar; Martínez S, Javier; ARAYA O, JUAN CARLOS; Villaseca H, Miguel; GUZMÁN G, PABLO; ROA E, IVÁN Article REVISTA MEDICA DE CHILE (2004)
Promoter methylation profile in breast cancer Roa, Jc; Anabalon, L; Tapia O.; Martinez, J.; Araya, JC; Villaseca M.; Guzman P.; Roa, I Article ISI REVISTA MEDICA DE CHILE (2004)
Pólipos y adenomas de la vesícula biliar: consideraciones clínico-patológicas ROA E, IVÁN; Aretxabala U, Xabier de; Morgan F, René; Molina U, Ricardo; Araya O, Juan C; Roa S, Juan; Ibacahe S, Gilda Article REVISTA MEDICA DE CHILE (2004)
Quimiorradioterapia de neoadyuvancia en cáncer de vesícula biliar DE ARETXABALA U, XABIER; LOSADA M, HÉCTOR; MORA P, JAVIER; ROA E, IVÁN; BURGOS S, LUIS; Yáñez R, Eduardo; Quijada P, Ingrid; Roa S, Juan Carlos Article REVISTA MEDICA DE CHILE (2004)
Relación de la genotipificación de Helicobacter pylori con la forma e intensidad de la gastritis en población adulta portadora de patología gástrica benigna ARAYA O, JUAN CARLOS; Anabalón R, Leonardo; ROA E, IVÁN; Bravo E, María; Villaseca H, Miguel Ángel; GUZMÁN G, PABLO; Roa S, Juan Carlos Article REVISTA MEDICA DE CHILE (2004)
HFE Gene Mutations in Chile [5] (multiple letters) Wohllk N.; Zapata, R; Acuña M.; Reyes, H.; Navarro, A; Roa, I; Roa, J.C Article ANNALS OF INTERNAL MEDICINE (2003)
Hipofosfatemia revertida al extirpar hemangioendotelioma compuesto del dedo mayor del pie Sapunar Z, Jorge; Roa S, Juan Carlos; Moscoso A, Susana Article REVISTA MEDICA DE CHILE (2003)
Hipotiroidismo primario luego de la resección de un Struma ovarii: Report of one case Sapunar Z, Jorge; Roa S, Juan Carlos; Meissner Sch, Arturo Article REVISTA MEDICA DE CHILE (2003)
Human papilloma virus (HPV) typing in preneoplastic and neoplastic lesions of the uterine cervix in the IX region-Chile Melo A.; Montenegro, S; Hooper, T; Capurro I; Roa, Jc; Roa, I Article REVISTA MEDICA DE CHILE (2003)
Hypothyroidism after the excision of a Struma ovarii. Report of one case Sapunar, J; Roa, Jc; Meissner, A Article ISI REVISTA MEDICA DE CHILE (2003)
Inestabilidad microsatelital y pérdida de la heterocigocidad en lesiones neoplásicas y preneoplásicas gástricas Roa S, Juan Carlos; ARAYA O, JUAN CARLOS; Villaseca H, Miguel Ángel; ROA E, IVÁN; Correa, Pelayo Article REVISTA MEDICA DE CHILE (2003)
Microsatellite instability and allelic imbalance in neoplastic and preneoplastic gastric lesions Roa, Jc; Araya, JC; Villaseca, MA; Roa, I; Correa P. Article ISI REVISTA MEDICA DE CHILE (2003)
Microsatellite instability and loss of heterozygosity in chronic gastritis Roa, Jc; Villaseca, MA; Roa L.; Araya, JC Article ISI REVISTA MEDICA DE CHILE (2003)
Mutación puntual del gen supresor de tumores TP53 en lesiones preneoplásicas y neoplásicas del estómago: cross- sectional study in a high risk region ARAYA O, JUAN CARLOS; Roa S, Juan Carlos; Villaseca H, Miguel Ángel; ROA E, IVÁN; GUZMÁN G, PABLO; Alvarado C, César Article REVISTA MEDICA DE CHILE (2003)
Mutations of TP53 suppressor gene in pre-neoplastic and neoplastic lesions of the stomach: cross-sectional study in a high risk region Araya, JC; Roa, Jc; Villaseca, MA; Roa, I; Guzman P.; Alvarado, C; Melo A. Article ISI REVISTA MEDICA DE CHILE (2003)
Tipificación del virus papiloma humano (VPH) en lesiones preneoplásicas y carcinoma del cuello uterino en mujeres de la IX Región-Chile Melo A, Angélica; Montenegro H, Sonia; Hooper, Terryl; CAPURRO V, ITALO; Roa S, Juan Carlos; ROA E, IVÁN Article REVISTA MEDICA DE CHILE (2003)
TRANSCRIPTOS DE FUSIÓN DEL GEN BCR/ABL EN PACIENTES CON LEUCEMIA MIELOIDE CRÓNICA Artigas, Carmen Gloria; Melo, Angelica; Roa, Juan Carlos; Roa, Ivan; Quijada, Ingrid; Vittini, Cecilia; Cabrera, María Elena; Risueño, Concepción Article International Journal of Morphology (2003)
Detección de secuencias del gen BCR-ABL mediante RT-PCR en pacientes con leucemia en la IX Región: Chile Artigas A, Carmen Gloria; Melo A, Angélica; Roa S, Juan Carlos; Páez F, Eduardo; Vittini de R, Cecilia; Arriagada M, Mónica; González O, Luis; Pflaumer F, Erna; ROA E, IVÁN Article REVISTA MEDICA DE CHILE (2002)
Detection of BCR-ABL gene sequences using polymerase chain reaction-reverse transcriptase in patients with leukemia Artigas, CG; Melo A.; Roa, Jc; Paez E.; de Vittini, C; Arriagada M.; Gonzalez L.; Pflaumer, E; Roa, I Article ISI REVISTA MEDICA DE CHILE (2002)
Elementos morfológicos pronósticos en el cáncer de la vesícula biliar ROA E, IVÁN; DE ARETXABALA U, XABIER; Araya O, Juan C; Villaseca H, Miguel; Roa S, Juan; Ibacache S, TM Gilda; BURGOS S, LUIS; Muñoz N, Sergio Article REVISTA MEDICA DE CHILE (2002)
Expression of cadherine-catenine complex in subserous gallbladder carcinoma Roa, I; Ibacache, G; Melo A.; Morales E. ; Villaseca M.; Araya J.; Roa, J; Guzman P.; De Aretxabala X. Article ISI REVISTA MEDICA DE CHILE (2002)
Is gallbladder cancer a tumor with bad prognosis? Roa, I; De Aretxabala X.; Roa, J; Araya, JC; Villaseca M.; Guzman P.; Burgos, L. Article ISI REVISTA MEDICA DE CHILE (2002)
Morphological prognostic factors in gallbladder cancer Roa, I; De Aretxabala X.; Araya, JC; Villaseca M.; Roa, J; Ibacache, TMG; Burgos, L.; Munoz S. Article ISI REVISTA MEDICA DE CHILE (2002)
¿Es el cáncer de la vesícula biliar una enfermedad de mal pronóstico en Chile? ROA E, IVÁN; DE ARETXABALA U, XABIER; Roa S, Juan; Araya O, Juan C; Villaseca H, Miguel; GUZMÁN G, PABLO; BURGOS S, LUIS Article REVISTA MEDICA DE CHILE (2002)
CD44 (HCAM) expression in subserous gallbladder carcinoma Roa, I; Villaseca M.; Araya J.; Roa, J; De Aretxabala X.; Ibacache, G; García, M Article ISI REVISTA MEDICA DE CHILE (2001)
Clinical and pathological features of early gallbladder carcinoma Roa, I; De Aretxabala X.; Araya, JC; Villaseca M.; Roa, J; Guzman P. Article ISI REVISTA MEDICA DE CHILE (2001)
Helicobacter pylori: cagA status and vacA genotyping in Chile. Detection of a s2/m1 strain Martinez, TA; Gonzalez, CC; Kawaguchi, PF; Montoya R.; Corvalan, A; Madariaga, J; Roa, J; Garcia, CA; Salgado, F; Solar, H; Palma M. Article REVISTA MEDICA DE CHILE (2001)
MOLECULAS DE ADHESION CELULAR Y CANCER Araya, Juan; de Aretxabala, Xabier; Miranda, Marcos; Roa, Ivan; Roa, Juan; Villaseca, Miguel Article REVISTA CHILENA DE CIRUGIA (2001)
Pathological findings in surgical reinterventions for gallbladder cancer in patients with and without preoperative chemo and radiotherapy Roa, I; De Aretxabala X.; Araya, JC; Villaseca M.; Roa, J; Burgos, L.; Guzman P. Article ISI REVISTA MEDICA DE CHILE (2001)
Gastric cancer and tumor growth regulation. Study of cell proliferation markers and protein complex p53/p21(WAF1/CIP1)/mdm-2 Villaseca M.; Araya, JC; Roa, I; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2000)
Helicobacter pylori and chronic gastritis: Relationship between infection and inflammatory activity in a high risk population for gastric cancer Araya, JC; Villaseca, MA; Roa, I; Roa, Jc Article ISI REVISTA MEDICA DE CHILE (2000)
Microsatellite instability, prognosis and metastasis in gastric cancers from a low-risk population Schneider, BG; Bravo, JC; Roa, Jc; Roa, I; Kim, MC; Lee, KM; Plaisance, KT; McBride, CM; Mera R. Article ISI SCOPUS INTERNATIONAL JOURNAL OF CANCER (2000)
p53 gene mutation in colorectal carcinoma Roa, Jc; Roa, I; Melo A.; Araya, JC; Villaseca, MA; Flores M.; Schneider, B Article ISI REVISTA MEDICA DE CHILE (2000)
P53 Gene mutation in gallbladder cancer Roa, I; Melo A.; Roa, J; Araya J.; Villaseca M.; De Aretxabala X. Article ISI REVISTA MEDICA DE CHILE (2000)
Use of combined consensus human papillomavirus (HPV) DNA amplification for detection and identification of HPV in parafin-embedded cervical specimens Montenegro-James, S; Melo A.; Anderson, L.; Kohli, T; Roa, Jc; Roa, I Article CLINICAL INFECTIOUS DISEASES (2000)
Peritoneal pseudomyxoma in a child with a gallbladder Peutz-Jeghers- like hamartomatous polyp: A case report Guzman P.; Roa, I; Villaseca M.; Roa, J.C; Araya J.C. Article JOURNAL OF PEDIATRIC SURGERY (1998)
DNA ploidy pattern and tumor suppressor gene p53 expression in gallbladder carcinoma Roa, I; Villaseca M.; Araya J.C.; Roa, J; Fuentealba P.; Melo A.; De Arctxabala X. Article CANCER EPIDEMIOLOGY BIOMARKERS AND PREVENTION (1997)
Double immunostaining for p53 and molecular chaperone hsp72/73 in gastric carcinoma Villaseca M.A.; Roa, I; Araya J.C.; Roa, J.C; Flores P. Article Journal of Clinical Pathology - Molecular Pathology (1997)
p53 tumour suppressor gene protein expression in early and advanced gallbladder carcinoma Roa, I; Villaseca M.; Araya J.; Roa, J; Melo A.; Ibacache, G; De Aretxabala X. Article HISTOPATHOLOGY (1997)
Preneoplastic lesions and gallbladder cancer: An estimate of the period required for progression Roa, I; Araya J.C.; Villaseca M.; De Aretxabala X.; Riedemann P.; Endoh K.; Roa, J Article GASTROENTEROLOGY (1996)
Alteraciones genéticas en gastritis crónica: Estudio de inestabilidad microsatelital y pérdida de la heterocigocidad Roa S, Juan Carlos; Villaseca V, Miguel Angel; ROA E, IVÁN; ARAYA O, JUAN CARLOS Article REVISTA MEDICA DE CHILE
Carcinoma incipiente de la vesícula biliar: Estudio clínico-patológico y pronóstico de 196 casos ROA E, IVÁN; DE ARETXABALA U, XABIER; Araya O, Juan C; Villaseca H, Miguel; Roa S, Juan; GUZMÁN G, PABLO Article REVISTA MEDICA DE CHILE
Carcinoma subseroso de la vesícula biliar: expresión del complejo caderina-catenina ROA E, IVÁN; IBACACHE S, GILDA; Melo A, Angélica; Morales M, Erick; Villaseca H, Miguel; Araya O, Juan; Roa S, Juan; GUZMÁN G, PABLO; DE ARETXABALA U, XABIER Article REVISTA MEDICA DE CHILE
Contenido de ADN y sobrevida en el carcinoma subseroso de la vesícula biliar ROA E, IVÁN; Aretxabala U, Xabier de; Fuentealba A, Patricia; Cabrera C, María Elena; Araya O, Juan C; Roa S, Juan Article REVISTA MEDICA DE CHILE
Cáncer de la vesícula biliar: Manejo de pacientes con invasión de la túnica muscular DE ARETXABALA U, XABIER; ROA E, IVÁN; MORA P, JAVIER; Pincheira S, Oscar; BURGOS SJ, LUIS; SILVA A, JORGE; Roa S, Juan Carlos Article REVISTA MEDICA DE CHILE
Descripción de genotipos de Echinococcus granulosus obtenidos de especímenes de hidatidosis humana Manterola, Carlos; Melo, Angelica; Vial, Manuel; Roa, Juan Carlos; MORA, JAVIER Article REVISTA CHILENA DE CIRUGIA
Detección de micrometástasis en médula ósea de pacientes con cáncer de vesícula biliar Roa S, Juan C; DE ARETXABALA U, XABIER; Melo A, Angélica; Faria, Gaspar; Araya O, Juan C; Villaseca H, Miguel A; GUZMÁN G, PABLO; ROA E, IVÁN Article REVISTA MEDICA DE CHILE
Estudio comparativo de detección del virus papiloma humano (VPH) en muestras citológicas y biopsias de cuello uterino Melo A, Angélica; ROA E, IVÁN; Montenegro H, Sonia; CAPURRO V, ITALO; Roa S, Juan Carlos Article REVISTA MEDICA DE CHILE
EVALUATION OF ZAR1 AND SFRP4 METHYLATION STATUS AS POTENTIAL BIOMARKERS FOR DIAGNOSIS AND PROGRESSION IN CERVICAL CARCINOGENESIS: EXPLORATORY STUDY PHASE I Roa, Jc Article BIOMARKERS
Mutación del gen K-ras en el cáncer de la vesícula biliar Roa S, Juan Carlos; ROA E, IVÁN; Aretxabala U, Xabier de; Melo A, Angélica; Faría O, Gaspar; Tapia E, Oscar Article REVISTA MEDICA DE CHILE


FISH'ing to Verify the Nature of Different Epithelial Alterations in the Gallbladder: Molecular Abnormalities Are Common in Neoplastic but Not in Reactive Lesions, Thus Validating the Santiago Criteria and Potential Usefulness of FISH as an Adjunct in Diagnosis Reid, MD; Graham, R; Memis, B; Kipp, B; Fritcher, EB; Roa, JC; Araya, JC; Villaseca, MA; Bellolio, E; Losada, H; Sarmiento, JM; Koshiol, J; Adsay, V Abstract ISI LABORATORY INVESTIGATION (2017)
Histologic Definition and Prognosis of "T3" Gallbladder Adenocarcinoma Obeng, RC; Memis, B; Muraki, T; Roa, JC; Araya, JC; Bellolio, E; Villaseca, M; Losada, H; Maithel, S; Sarmiento, JM; Cardona, K; Reid, MD; Adsay, V Abstract ISI LABORATORY INVESTIGATION (2017)
Impact of the Staging of Gastritis With the Olga System for Risk Stratification in a Chilean Population With High Prevalence of Gastric Cancer Vargas, JI; San Martin, D; Monrroy, H; Torres, J; Roa, JC; Jimenez, C; Cabrera, N; Zepeda, G; Demandes, H; Vidaurre, J; Latorre, G; Robles, C; Jimenez, M; Flandez, J; Gonzalez, RG; Candia, R; Espino, A; Riquelme, A Abstract ISI GASTROINTESTINAL ENDOSCOPY (2017)
Neuroendocrine Neoplasms of the Gallbladder. An Immunohistochemical and Clinicopathologic Analysis of 29 Cases Reid, MD; Roa, JC; Memis, B; Muraki, T; Araya, JC; Villaseca, M; Losada, H; Sarmiento, JM; Sica, G; Adsay, V Abstract ISI LABORATORY INVESTIGATION (2017)
Pathologic Findings from Totally Sampled and Mapped Gallbladders in a High-Risk Population Bellolio, E; Roa, JC; Villaseca, M; Ferreccio, C; Adsay, V; Losada, H; Van Dyke, A; Vivallo, C; Becker, R; Medina, K; fuentealba, p; Araya, JC; Koshiol, J Abstract ISI LABORATORY INVESTIGATION (2017)
Pathologic Findings in Gallbladders: An Analysis of the True Frequency and Distribution in 203 Totally Sampled and Mapped Gallbladders from a North American Population Memis, B; Reid, MD; Bedolla, G; Roa, JC; Araya, JC; Bellolio, E; Villaseca, M; Van Dyke, A; Xue, Y; Quigley, B; Krasinskas, A; Polito, H; Ghosh, A; Koshiol, J; Adsay, V Abstract ISI LABORATORY INVESTIGATION (2017)
Prognostic Validation of T2-Substaging of Gallbladder Carcinomas: Survival Analysis of 127 Korean Cases with T2 Substaging and Survival Correlation Chu, J; Jang, KT; Roa, JC; Hong, SM; Lee, KB; Koshiol, J; Memis, B; Muraki, T; Reid, MD; Goodman, MM; Nash, R; Jang, J; Adsay, V; Kim, H; Choi, H Abstract ISI LABORATORY INVESTIGATION (2017)
Endoscopic Therapy For Barrett's Esophagus: A Chilean Academic Hospital Experience Vivar, RM; Gonzalez, RG; Richter, H; Roa, JC; Torres, J; Chahuan, J; Uslar, T; Parra-Blanco, A; Espino, A Abstract ISI GASTROINTESTINAL ENDOSCOPY (2016)
Epithelial Atypia in the Gallbladder: Diagnosis and Classification in an International Consensus Study Adsay V.; Roa, Jc; Basturk O.; Torres J.; Mucientes, F; del Pozo M.; Villaseca, MA; Aguayo, G; Bellolio, ER; Araya, JC; Endo I.; Lee, K; Jang, KT; Jang, JY; Ohike, N; Shimizu, M; Hirabayashi, K; Terris, B; Zamboni, G; Reid, M; Xue, Y; Bedolla, G; Quigley, B; Krasinskas, A; Akkas G.; Memis B.; Klimstra, D; Hruban, RH; Zhu, B; Van Dyke, AL; Koshiol, J Abstract ISI LABORATORY INVESTIGATION (2016)
Marked Geographic Differences in the Pathologic Diagnosis of Non-Invasive (Tis) vs Minimally Invasive (T1) Gallbladder Cancer: Santiago Consensus Conference Highlights the Need for the Unifying Category "Early Gallbladder Cancer" (EGBC) Roa, Jc; Basturk O.; Torres J.; Mucientes, F; del Pozo M.; Villaseca, MA; Aguayo, G; Bellolio, ER; Araya, JC; Endo I.; Jang, KT; Lee, K; Jang, JY; Ohike, N; Shimizu, M; Hirabayashi, K; Terris, B; Zamboni, G; Reid, M; Xue, Y; Bedolla, G; Quigley, B; Krasinskas, AM; Akkas G.; Memis B.; Klimstra, D; Hruban, RH; Zhu, B; Van Dyke, AL; Koshiol, J; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2016)
Not All T2 Gallbladder Carcinomas (GBC) Are Equal: Proposal for Sub- Staging of T2 GBC with Significant Prognostic Value Memis B.; Roa, Jc; Muraki, T; Hacihasanoglu, E; Dursun N.; Saka B.; Bellolio, ER; Araya, JC; Sarmiento J.; Losada H.; Kooby, D; Maithel, S; Reid, M; Quigley, B; Krasinskas, A; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2016)
Not All T2 Gallbladder Carcinomas (GBC) Are Equal: Proposal for Sub-Staging of T2 GBC with Significant Prognostic Value Memis B.; Roa, Jc; Muraki, T; Hacihasanoglu, E; Dursun N.; Saka B.; Bellolio, ER; Araya, JC; Sarmiento J.; Losada H.; Kooby, D; Maithel, S; Reid, M; Quigley, B; Krasinskas, A; Adsay V. Abstract ISI MODERN PATHOLOGY (2016)
Prognosis of T2 Gallbladder Carcinomas: An Analysis of 326 Cases Highlights a Prognosis Better Than the Current Impression in the West, but Incomparably Worse Than What Is Reported in Asia Memis B.; Roa, Jc; Muraki, T; Jang, KT; Bellolio, ER; Araya, JC; Villaseca, MA; Sarmiento J.; Losada H.; Maithel, S; Kooby, D; Dursun N.; Polito, H; Bandyopadhyay, S; Bagci P.; Saka B.; Reid, M; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2016)
Adenomyomatous Nodules of the Gallbladder: Clinicopathologic Analysis of 234 Cases, Including 20 With Neoplastic Transformation Dursun N.; Okcu, O; Memis B.; Akkas G.; Everett, R; Basturk O.; Bagci P.; Balci, S; Saka B.; Quigley, B; Krasinskas, A; Roa, J; Fang, KT; Sarmiento J.; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2015)
Clinicopathologic Analysis of 21 Deceptively Benign-Appearing Adenocarcinomas ("Adenoma Malignum") of the Gallbladder and Their Differential Diagnosis From Pseudoinfiltrative Processes Memis B.; Quigley, B; Reid, M; Dursun N.; Akkas G.; Karaaslan, S; Basturk O.; Saka B.; Bagci P.; Balci, S; Krasinskas, A; Roa, J; Escalona, O; Sarmiento J.; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2015)
Comparative Genetic Analysis of Invasion-Resistant (Complex Non-Mucinous Pyloric) and Invasion-Prone Types of Intracholecytstic Papillary-Tubular Neoplasms of the Gallbladder Robinson, B; Fisher, K; Xu, JP; Balci, S; Rossi, M; Moreno C.; Quigley, B; Reid, M; Roa, J; Basturk O.; Terry, P; Krasinskas, A; Hruban, R; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2015)
FIRST TRIMESTER MULTIPARAMETRIC MODEL FOR GESTATIONAL DIABETES PREDICTION Correa P.; Venegas P.; Rice, G; Salomon, C; Montenegro L.; Olguín J; Roa, J; Cortes, J; Nien JK; Illanes, S Abstract ISI PLACENTA (2015)
Gallbladder Carcinomas With Sarcomatoid Component: Clinicopathologic Analysis of 11 Cases Akkas G.; Memis B.; Bagci P.; Dursun N.; Saka B.; Basturk O.; Fang, KT; Roa, J; Sarmiento J.; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2015)
HSP90 Expression and Antitumoral Activity of Geldanamicin and Its Analog in Gallbladder Carcinoma Valbuena J.; Weber, H; Leal P.; Garcia P.; Bizama, C; Espinoza J.; Roa, J Abstract ISI LABORATORY INVESTIGATION (2015)
Pathologic Diagnosis as the Reason for Wide Discrepancies in the Literature Regarding the Incidence and Behavior of T1 Gallbladder Cancer (GBC): An Analysis of 473 GBC and Comparison With Literature Akkas G.; Memis B.; Basturk O.; Quigley, B; Karaaslan, S; Saka B.; Dursun N.; Bagci P.; Balci, S; Sarmiento J.; Bandyopadhyay, S; Escalona, O; Goodman, M.; Knight, J; Krasinskas, A; Roa, J; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2015)
Pathologic Evaluation and Reporting of Intraductal Papillary Mucinous Neoplasms of the Pancreas: Recommendations of Verona Consensus Meeting Basturk O.; Mino-Kenudson, M; Furukowa, T; Zamboni, G; Marchegiani, G; Bassi C.; Salvia R.; Malleo, G; Paiella, S; Wolfgang, C; Matthaei, H; Offerhaus, G; Adham, M; Bruno M.; Reid, M; Krasinskas, A; Kloppel, G; Ohike, N; Tajiri, T; Jang, KT; Roa, J; Allen P.; Fernandez-del Castillo, C; Jang, JY; Klimstra, D; Hruban, R; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2015)
Stat3 and ErbB-2 interaction in breast cancer metastasis Venturutti L.; Romero, LV; Urtreger, AJ; Chervo, MF; Mercogliano, MF; Russo, RIC; Pereyra, MG; Inurrigarro G.; Flaque, MCD; Sunblad, V; Roa, Jc; Guzman P.; de Kier-Joffe, EB; Charreau, EH; Schillaci R.; Elizalde, PV Abstract ISI CANCER RESEARCH (2015)
Biologic Behavior of Gallbladder High-Grade Dysplasia: A Long-Term Survival Analysis of 125 Cases Elucidates a Mostly Curable Disease, Which Is a Marker of Biliary Tract Cancer Risk in Some Patients Dursun N.; Saka B.; Balci, S; Bagci P.; Roa, Jc; Araya, JC; Basturk O.; Terry, P; Minhas, F; Ducato, L; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2014)
Carcinoma In-Situ of the Gallbladder: The SEER Database Perspective Patel, K; Balci, S; Saka B.; Knight, J; Basturk O.; Sarmiento J.; Roa, Jc; Araya, JC; Sweeney, J; Terry, P; Goodman, M.; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2014)
Complex Tubular Type Intracholecystic Papillary Tubular Neoplasms (ICPN): Further Clinicopathologic and Molecular Characterization Balci, S; Bagci P.; Dursun N.; Jang, KT; Saka B.; Ohike, N; Roa, Jc; Tajiri, T; Moreno C.; Rossi, M; Xu, J; Hruban, R; Matthaei, H; Fisher, K; Terry, P; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2014)
Immunophenotypic Characteristics and Classification of Non-Tumoral (Flat) Gallbladder Dysplasia Saka B.; Balci, S; Dursun N.; Bagci P.; Jang, KT; Roa, Jc; Terry, P; Genco, I; Basturk O.; Adsay V. Abstract ISI LABORATORY INVESTIGATION (2014)
mTOR/P70S6K signaling pathway as a potential target for advanced gallbladder cancer therapy Roa, Jc; Leal P.; Weber, H; Garcia P.; Sandoval A.; Buchegger, K; Tapia O.; Nervi, B; Grez, M Abstract ISI JOURNAL OF CLINICAL ONCOLOGY (2014)
Second-line FOLFOX chemotherapy in patients with metastatic gallbladder cancer and cholangiocarcinoma Leal, JL; Roa, Jc; Jarufe, N; Madrid J.; Ibáñez C; Herrera, ME; Garrido M.; Nervi, B Abstract ISI JOURNAL OF CLINICAL ONCOLOGY (2014)
Adenomatous (Dysplastic) Transformation in Cholesterol Polyps (CPs) of the Gallbladder (GB) Saka B.; Bagci P.; Dursun N.; Basturk O.; Roa, Jc; Jang, KT; Tapia O.; Losada H.; Sarmiento J.; Tajiri, T; Adsay V. Abstract LABORATORY INVESTIGATION (2013)
Cellular Phenotypes in Gallbladder Dysplasia: Diagnostic Significance and Clinical Associations in an Analysis of 318 Cases Bagci P.; Saka B.; Erbarut, I; Dursun N.; Basturk O.; Roa, Jc; Escalona, OT; Losada H.; Jang, KT; Kong, SY; Farris, AB; Adsay V. Abstract LABORATORY INVESTIGATION (2013)
Expression Analysis of AKT/mTOR Signaling Pathway in Primary Tumors and Cell Lines Derived from Gallbladder Cancer Roa, Jc; Leal P.; Garcia P.; Tapia O.; Weber, H Abstract LABORATORY INVESTIGATION (2013)
Expression of vascular endothelial growth factor a (VEGF-A) in advanced gallbladder cancer Letelier P; Buchegger, K; Ili C.; Garcia P.; Brevi, P; Sandoval A.; Leal P.; Riquelme I.; Roa, Jc Abstract ISI CANCER RESEARCH (2013)
HSP90 expression and antitumoral activity of geldanamycin and its analog 17-AAG in gallbladder cancer. Valbuena, JR; Roa, Jc; Leal, PA; Garcia, PA; Corvalan, A Abstract ISI CANCER RESEARCH (2013)
Human papillomavirus genotyping in urine samples of women with squamous intraepithelial lesions of cervix Viscarra, T; Andana, A; Brebi P.; Menzel, D; Ili CG; Silva R.; Roa, Jc; Sanchez R. Abstract ISI CANCER RESEARCH (2013)
Identification of circulating HPV DNA in urine with a dual sequence capture approach. Guerrero-Preston, RE; Jedlicka, A; Diaz-Montes, T; Romaguera J.; Roa, Jc; Sidransky D. Abstract ISI CANCER RESEARCH (2013)
Is 1 cm a Valid Cut-Off as the Cholecystectomy Indication for Gallbladder Polyps?: Clinicopathologic Analysis of 432 Cases Dursun N.; Bagci P.; Saka B.; Basturk O.; Vance C.; Roa, Jc; Tapia O.; Losada H.; Sarmiento J.; Jang, KT; Tajiri, T; Cigerciogullari, E; Kong, SY; Goodman, M.; Adsay V. Abstract LABORATORY INVESTIGATION (2013)
Follicular Cholecystitis: Reappraisal of Incidence, Definition and Clinicopathologic Associations in an Analysis of 2413 Cholecystectomies Saka B.; Bagci P.; Dursun N.; Bandyopadhyay, S; Tapia, OE; Roa, Jc; Jang, KT; Farris, AB; Kong, SY; Kasimoglu, IZ; Adsay V. Abstract LABORATORY INVESTIGATION (2012)
Heat Shock Protein (HSP)-90 Is Overexpressed in Gallbladder Carcinoma (GBC) Valbuena, JR; Roa, Jc; Leal P.; Garcia P.; Gonzalez S.; Oddo D.; Schnettler K.; Carrasco, G; Corvalan, AH Abstract LABORATORY INVESTIGATION (2012)
Poorly Cohesive Cell (Diffuse-Infiltrative/Signet-Ring) Carcinomas of the Gallbladder (GB): Clinicopathologic Analysis of 24 Cases Identified in 628 GB Carcinomas Patel, S; Roa, Jc; Bagci P.; Tapia O.; Jang, KT; Lim M.; Dursun N.; Saka B.; Ducato, L; Basturk O.; Sarmiento J.; Adsay, NV Abstract LABORATORY INVESTIGATION (2012)
The Significance of Poorly Differentiated (Undifferentiated) Component in Gallbladder Carcinomas (GBC): Clinicopathologic Analysis of 54 Cases Identified in 628 GBC Basturk O.; Bagci P.; Tapia O.; Roa, Jc; Jang, KT; Dursun N.; Patel, S; Cheng, J; Bandyopadhyay, S; Erbarut, I; Kong, SY; Sarmiento J.; Adsay V. Abstract LABORATORY INVESTIGATION (2012)
Classification of Tumoral Intraepithelial Neoplasms of the Gallbladder under a Unified Category of Intracholecystic Papillary Tubular Neoplasms (ICPN) with 4 Subsets Discernible by Correlation of Morphology and Immunophenotype Jung, KT; Dursun N.; Bastruk, O; Roa, Jc; Tapia O.; Terry, P; Adsay, N Abstract ISI LABORATORY INVESTIGATION (2011)
Immunohistochemical Analysis of the Progression of Flat Versus Tumoral Intraepithelial Neoplasia (Intracholecysitc Papillary-Tubular Neoplasm) in Gallbladder Carcinogenesis Jung, KT; Dursun N.; Basturk O.; Roa, Jc; Tapia O.; Terry, P; Adsay, N Abstract ISI LABORATORY INVESTIGATION (2011)
Metaplasia in the Gallbladder: An Analysis of Clinicopathologic Associations in 1218 Cholecystectomies Dursun N.; Roa, Jc; Tapia O.; Basturk O.; Bandyopadhyay, S; Cakir, A.; Goodman, M.; Sarmiento J.; Losada H.; Adsay, N Abstract ISI MODERN PATHOLOGY (2011)
Metaplasia in the Gallbladder: An Analysis of Clinicopathologic Associations in 1218 Cholecystectomies. Dursun N.; Roa, Jc; Tapia O.; Basturk O.; Bandyopadhyay, S; Cakir, A.; Goodman, M.; Sarmiento J.; Losada H.; Adsay, N Abstract ISI LABORATORY INVESTIGATION (2011)
Mucosal Predominant Lymphoplasmacytic Inflammation May Be Associated with but Is Not Specific for Autoimmune and Distal Obstructive Biliary Pathology: An Analysis of 998 Cholecystectomies and Proposal for Diffuse Chronic Superficial Cholecystitis as the Category Designation Saka B.; Dursun N.; Basturk O.; Ducato, L; Bagci P.; Tapia O.; Roa, Jc; Bandyopadhyay, S; Adsay, N Abstract ISI MODERN PATHOLOGY (2011)
Mucosal Predominant Lymphoplasmacytic Inflammation May Be Associated with but Is Not Specific for Autoimmune and Distal Obstructive Biliary Pathology: An Analysis of 998 Cholecystectomies and Proposal for Diffuse Chronic Superficial Cholecystitis as the Category Designation. Saka B.; Dursun N.; Basturk O.; Ducato, L; Bagci P.; Tapia O.; Roa, Jc; Bandyopadhyay, S; Adsay, N Abstract ISI LABORATORY INVESTIGATION (2011)
Non-Neoplastic Polyps of the Gallbladder: Incidence, Histologic Types, and Clinicopathologic Associations in an Analysis of 162 Cases Vance, CE; Roa, Jc; Dursun N.; Tapia O.; Ducato, L; Saka B.; Jang, KT; Losada H.; Sarmiento J.; Bandyopadhyay, S; Adsay, N Abstract ISI LABORATORY INVESTIGATION (2011)
Patterns and Significance of Eosinophils in Gallbladder Injury: An Analysis of 1050 Cholecystectomies Saka B.; Dursun N.; Basturk O.; Roa, Jc; Tapia O.; Bandyopadhyay, S; Ducato, L; Bagci P.; Adsay, N Abstract ISI LABORATORY INVESTIGATION (2011)
Intravesicular Papillary-Tubular Neoplasm (IVPN) as a Unifying Category for Mass-Forming Preinvasive Neoplasms of the Gallbladder: An Analysis of 87 Cases Dursun N.; Roa, Jc; Tapia O.; Cakir, A.; Coban, I; Basturk O.; Akdemir, D; Sarmiento J.; Losada H.; Adsay, NV Abstract LABORATORY INVESTIGATION (2010)
Mucinous Carcinoma (MC) of the Gallbladder (GB): Clinicopathologic Analysis of 14 Cases Identified among 606 GB Carcinomas Tapia O.; Roa, Jc; Cakir, A.; Dursun N.; Coban, I; Basturk O.; Cheng, J; Sarmiento J.; Losada H.; Adsay, NV Abstract LABORATORY INVESTIGATION (2010)
Neuroendocrine Carcinomas of the Gallbladder: A Clinicopathologic Analysis of 23 Cases Sica, G; Dursun N.; Roa, Jc; Tapia O.; Cakir, A.; Coban, I; Sarmiento J.; Basturk O.; Ohike, N; Cheng, J; Adsay, NV Abstract LABORATORY INVESTIGATION (2010)
Sclerocalcifying Cholecystitis (ScICC) and Associated Carcinomas: Characterization of a Clinicopathologically Distinct and Challenging Entity Patel, S; Tapia O.; Roa, Jc; Cakir, A.; Dursun N.; Basturk O.; Akdemir, D; Bandyopadhyay, S; Sarmiento J.; Coban, I; Adsay, NV Abstract ISI LABORATORY INVESTIGATION (2010)
Sclerocalcifying Cholecystitis (SclCC) and Associated Carcinomas: Characterization of a Clinicopathologically Distinct and Challenging Entity Patel, S; Tapia O.; Roa, Jc; Cakir, A.; Dursun N.; Basturk O.; Akdemir, D; Bandyopadhyay, S; Sarmiento J.; Coban, I; Adsay, NV Abstract MODERN PATHOLOGY (2010)
Squamous Cell and Adenosquamous Carcinomas of the Gallbladder: Clinicopathologic Analysis of 34 Cases Cakir, A.; Tapia O.; Roa, Jc; Dursun N.; Coban, I; Basturk O.; Jazaerly, T; Akdemir, D; Sarmiento J.; Adsay, NV Abstract LABORATORY INVESTIGATION (2010)
Metaplasia in the Gallbladder: Populational Differences in the Incidence of Intestinal Metaplasia Supports Its Association with Carcinoma Basturk O.; Tapia O.; Roa, Jc; Bellolio E.; Delgado C.; Bandyopadhyay, S; Coban, I; Thirabanjasak, D; Sarmiento, JM; Losada H.; Adsay, NV Abstract LABORATORY INVESTIGATION (2009)
Body site distribution of squamous cell carcinoma in Chile. Analysis in two socioeconomic strata Zemelman, V; VALENZUELA, CY; Tomulic, V; Zamalloa, G; Roa, J Abstract ISI BRITISH JOURNAL OF DERMATOLOGY (2008)
Methylation profile as a prognostic factor in advanced gallbladder cancer Roa, J; Garcia P.; Sanhueza, A; Manterola C.; Araya J.; Vilaseca, M; Guzman P.; Anabalon, L Abstract ANNALS OF ONCOLOGY (2007)
Local immune response and virulence factors of Helicobacter pylori infection in Chile Araya, JC; Roa, Jc; Cuba M.; Anabalon, L; Sierralta A.; Rios E.; Roa, I Abstract HELICOBACTER (2005)
Regions of allelic imbalance on chromosome 12q in human gastric cancers. Schneider, BG; Rha, SY; Chung, HC; Bran, JC; Mera R.; Roa, Jc; Roa, I; Plaisance, KT; Schlegel, R; McBride, CM; Leach, RJ Abstract FASEB JOURNAL (2002)
Characterisation of motoneurones and interneurones in mouse dissociated spinal cord cultures Roa, J; Aguayo, LG; Tapia, JC; Mentis, GZ; Diaz, E.; Moran, LB; Navarrete R. Abstract ISI JOURNAL OF PHYSIOLOGY-LONDON (2000)


Diagnóstico de la infección por virus papiloma humano en el hombre Silva, Ramón; León, Daniela; Brebi, Priscilla.; Ili, Carmen; Roa, Juan C.; Sánchez, Raúl Actualizacion SCIELO REVISTA CHILENA DE INFECTOLOGIA (2013)


Molecular Pathology of Gallbladder Cancer Roa, J.C; Adsay V.; Cheng L.; Eble, J.N BookSection Molecular Surgical Pathology (2013)
Biología Molecular del Cáncer de Páncreas Roa, J.C BookSection CIRUGIA PANCREATICA (2012)
Molecular Pathology of Neoplasms of Extrahepatic Bile Ducts Katabi, N; Roa, J.C; Adsay V. BookSection MOLECULAR PATHOLOGY OF LIVER DISEASES (2011)
Neoplasms of the Gallbladder Roa, J.C; Katabi, N; Adsay V. BookSection MOLECULAR PATHOLOGY OF LIVER DISEASES (2011)
Viral Cancers: Etiology, Pathogenesis and Treatment Brebi P.; Ili C.; Lopez, J.; Roa, J.C BookSection Nose and Viral Cancer: Etiology, Pathogenesis and Treatment (2009)
Future Directions in Gastric Cancer Research Roa, J.C; Leal P.; Cardinni, D BookSection Research Focus on Gastric Cancer Editors (2008)
Methylation in Cancer Research Roa, J.C; Garcia P.; Kobayashi T. BookSection DNA Methylation Research Trenes (2007)
Preneoplastic Lesions of a Gallbladder from Morphological and Molecular Point of View Roa, J.C; Roa, I BookSection New Research on Precancerous Conditions (2007)
Specific Gene Methylation as a Gastrointestinal Tumor Marker Roa, J.C; Villaseca M.; Chang, H BookSection Tumor Markers Research Focus (2007)
Consideraciones generales y genetico-moleculares del cáncer de los conductos biliares y de la vesícula biliar Roa, J.C BookSection CIRUGIA DEL HIGADO VIA BILIAR Y PANCREAS (2005)


Carcinosarcoma de la vesícula biliar: Caso clínico Tapia E, Oscar; Roa S, Juan Carlos; Antonio P, Lilia CaseReport SCIELO REVISTA CHILENA DE CIRUGIA (2011)
Atrofia vellositaria duodenal inducida por micofenolato mofetil: Caso clínico Tapia E, Oscar; Villaseca H, Miguel; SIERRALTA Z, ARMANDO; Roa S, Juan Carlos CaseReport SCIELO REVISTA MEDICA DE CHILE (2010)
Hidatidosis de la mama: Reporte de un caso Tapia E, Oscar; Pineda N, Viviana; Roa S, Juan Carlos CaseReport SCIELO REVISTA CHILENA DE CIRUGIA (2010)
Hidatidosis ósea: Reporte de 5 casos y revisión de la literatura Tapia E, Oscar; VIDAL T, AARÓN; Bellolio J, Enrique; Roa S, Juan Carlos CaseReport SCIELO REVISTA MEDICA DE CHILE (2010)
Adenocarcinoma gástrico primario concomitante con tumor estromal gastrointestinal: Reporte de un caso y revisión de literatura Antonio P, Lilia; GUZMÁN G, PABLO; Villaseca H, Miguel; Araya O, Juan; De Toro C, Gonzalo; Roa S, Juan CaseReport SCIELO REVISTA MEDICA DE CHILE (2009)
ADENOCARCINOMA ENDOMETRIAL CONCOMITANTE CON TUMOR ESTROMAL BENIGNO DEL ENDOMETRIO Antonio P, Lilia; GUZMÁN G, PABLO; Villaseca H, Miguel; Araya 0, Juan; Roa S, Juan CaseReport SCIELO Revista chilena de obstetricia y ginecología (2008)
Carcinoma papilar en quiste del conducto tirogloso: Reporte de dos casos GUZMÁN G, PABLO; Baeza O, Aníbal; Cabello V, Alvaro; Montecinos L, Angélica; Leal M, Cristian; Roa S, Juan CaseReport SCIELO REVISTA MEDICA DE CHILE (2008)
Colitis quística profunda posradioterapia: Caso clínico De Toro C, Gonzalo; Villaseca H, Miguel; Roa S, Juan Carlos CaseReport SCIELO REVISTA MEDICA DE CHILE (2007)
Hepatocarcinoma con componente sarcomatoide: Caso clínico LOSADA M, HÉCTOR; Roa, Juan Carlos; García M, Darío; Araya, Juan Carlos; BURGOS SJ, LUIS; SILVA A, JORGE CaseReport SCIELO REVISTA MEDICA DE CHILE (2007)


Expression Analysis of AKT/mTOR Signaling Pathway in Primary Tumors and Cell Lines Derived from Gallbladder Cancer Authors Roa, Jc ConferencePoster 15th International Conference on Electronics, Communications and Computers, Proceedings (2013)
Level of miR-125B and miR-451 and Deregulated Expression of PI3K/AKT/mTOR Pathway in Gastric Cancer Tapia O.; Riquelme I.; Sandoval A.; Letelier P; Leal P.; Roa, Jc ConferencePoster LABORATORY INVESTIGATION (2013)


Activated status of Hedgehog pathway in oral squamous cell carcinoma (OSCC): the door is still open Riquelme I.; Roa, Jc EditorialMaterial ISI SCOPUS TRANSLATIONAL CANCER RESEARCH (2016)
Genetic methylation in carcinogenesis and its application in clinical oncology Roa, Jc EditorialMaterial MEDICINA CLINICA (2006)


Author Correction: Circulating Levels of Inflammatory Proteins and Survival in Patients with Gallbladder Cancer (Scientific Reports, (2018), 8, 1, (5671), 10.1038/s41598-018-23848-8) Liu Z.; Kemp T.J.; Gao Y.-T.; Corbel A.; McGee E.E.; Roa, J.C; Wang B.; Araya J.C.; Shen M.-C.; Rashid A.; Hsing A.W.; Hildesheim A.; Ferreccio C.; Pfeiffer R.M.; Pinto L.A.; Koshiol J. Errata SCOPUS SCIENTIFIC REPORTS (2020)
Early gallbladder carcinoma has a favorable outcome but Rokitansky-Aschoff sinus involvement is an adverse prognostic factor (vol 463, pg 651, 2013) Roa, Jc; Tapia O.; Manterola C.; Villaseca M.; Guzman P.; Araya, JC; Bagci P.; Saka B.; Adsay V. Errata ISI SCOPUS Virchows Archiv (2013)


Synchronous ileocecal and duodenal tuberculosis: case report and review of the literature Villalón C.; Quezada, F.; Hartmann, J; Roa, Jc; Urrejola G Letter ISI SCOPUS INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2014)
Criteria for Pathologic Sampling of Gallbladder Specimens Adsay V.; Saka B.; Basturk O.; Roa, Jc Letter ISI SCOPUS American Journal of Clinical Pathology (2013)
HFE gene mutations in Chile Wohllk N.; Zapata, R; Acuña M.; Reyes, H.; Navarro, A; Roa, I; Roa, Jc Letter ANNALS OF INTERNAL MEDICINE (2003)


Novel genes and uses thereof, expression profile of colon, gastric and pancreatic cancer Manuel Gidekel,; Carolina Del Carmen Bizama Soto; Felipe Mario Benavente Muñoz; Hilda Ana Gutiérrez Moraga; Osvaldo Luis Podhajcer; Edgardo Enrique Salvatierra Colussi; Guillermo Daniel Mazzolini; Juan Carlos Roa Patent (2013)
Kit de deteccion y genotipificacion de HPV. “HPV easy typing” Roa, J.C; Melo A.; Brebi P.; Montenegro, S Patent


Establishment and Exploitation of a European-Latin American Research Consortium towards Eradication of Preventable Gallbladder Cancer (Eulat) H2020 (825741) Proyecto 2019-2025 Investigador(a)
European -latin american network for the assessment of biomarkers to predict and diagnose hepatobiliary malignacies and characterization of risk factors for cancer development. (ESCALON) H2020 (825510) Proyecto 2019-2023 Inv. Principal
CIRCULATING exoDNA AS A NEXT GENERATION BIOSPECIMEN FOR LIQUID BIOPSY OF PANCREATICBILIARY CANCERS FONDECYT (1170893) Proyecto 2017-2021 Inv. Principal
PLATFORM OF THERAPY RESPONSE PREDICTION AND DRUG SCREENING USING GALLBLADDER CANCER PATIENTSDERIVED ORGANOIDS FONDECYT (1171463) Proyecto 2017-2021 Coinvestigador(a)
PROTEOMIC SIGNATURE OF GALLBLADDER CANCER SECRETED EXOSOMES=> A DYNAMIC APPROACH TO DELINEATE THEIR POTENTIAL ROLE DURING MALIGNANT PROGRESSION AND THEIR CLINICAL RELEVANCE AS NOVEL RESERVOIR OF CIRCULATING BIOMARKERS. FONDECYT (1151008) Proyecto 2015-2019 Coinvestigador(a)
IDENTIFICACION Y VALIDACION DE BIOMARCADORES PRONOSTICOS Y POTENCIALES BLANCOS TERAPEUTICOS DE LA VIA DE SENALIZACION HIPPO EN PACIENTES CON CANCER DE VESICULA BILIAR FONDECYT (3140426) Proyecto 2013-2016 Inv. Patrocinante
IDENTIFICATION AND VALIDATION OF EARLY DIAGNOSTIC GALLBLADDER CANCER BIOMARKERS IN CHILEAN PATIENTS BY QUANTITATIVE PROTEOMICS. A PHASE 1 AND 2 BIOMARKER VALIDATION TRIAL." FONDECYT (1130204) Proyecto 2013-2017 Inv. Responsable
Pyrosequencing platform for epigenetic and polymorphism research FONDEQUIP (120205) Proyecto 2013-2015 Inv. Principal
TRANSCRIPTOMIC PROFILING OF GALLBLADDER CANCER PROGRESSION. FONDECYT (3140308) Proyecto 2013-2016 Inv. Patrocinante
A PILOT STUDY OF GALLBLADDER CANCER IN CHILE NCI-EEUU Proyecto 2012-2013 Coinvestigador(a)
IMPROVING THE PRODUCTION OF PHENYLPROPANOIDS WITH ANTIOXIDANT ACTIVITY IN HIGHBUSH BLUEBERRY (VACCINIUM CORYMBOSUM L.) USING METHYL JASMONATE AND UV-B RADIATION AND ITS EFFECT ON GASTRIC CANCER CHEMOPREVENTION. FONDECYT (1120917) Proyecto 2012-2016 Coinvestigador(a)
PLATAFORMA DE ESTUDIOS PRECLÍNICOS DE XENOTRANSPLANTES DE TEJIDOS METASTÁTICOS HUMANOS PARA LA EVALUACIÓN DE SENSIBILIDAD A DROGAS ANTICANCERÍGENAS FONDEF IDEAS (CA12i10333) Proyecto 2012-2014 Coinvestigador(a)
Preclinical platform of xenograft models of metastatic human tissues for evaluating anticancer drug sensitivity FONDEF (CA12i10333) Proyecto 2012-2014 Coinvestigador(a)
CENTRO DE EXCELENCIA EN STUDIOS GENETICOS E INMUNOLÓGICOS (CEGIN) Co Pi Corfo INNOVA (09CN 14-5960) Proyecto 2011-2014 Inv. Principal
DETECCION DE GENES HIPERMETILADOS EN CITOBRUSH, SUERO Y ORINA DE MUJERES CON NEOPLASIA CERVICAL COMO BIOMARCADORES DE DIAGNOSTICO PRECOZ, PROGRESION Y/O PRONOSTICO. FONDECYT (3120141) Proyecto 2011-2014 Inv. Patrocinante
VALIDATION OF MTOR METABOLIC PATHWAY INACTIVATION FOR GALLBLADDER CANCER TARGETED THERAPY FONDECYT (1090171) Proyecto 2009-2013 Inv. Responsable
KIT DE DETECCIÓN Y TIPIFICACIÓN DE HPV PARA DECISIONES TERAPÉUTICAS EN LESIONES PRENEOPLÁSICAS Y NEOPLÁSICAS DEL CUELLO UTERINO / CORFO-INNOVA. (07CN13PBT-222) Proyecto 2008-2011 Director(a)
Kit de Detección y Tipificación de HPV para Decisiones Terapéuticas en Lesiones Preneoplásicas y del Cuello Uterino Roa, Juan Carlos Proyecto (2008)
Concurso Incentivo a la Cooperacion Internacional Estudio del Patrón de Metilación Génico como Factor Pronostico en Carcinomas Subserosos Potencialmente Curables (pt2) de la Vesícula Biliar Roa, Juan Carlos Proyecto (2006)
ESTUDIO DEL PATRON DE METILACION GENICO COMO FACTOR PRONOSTICO EN CARCINOMAS SUBSEROSOS POTENCIALMENTE CURABLES (pT2) DE LA VESICULA BILIAR. FONDECYT (7060301) Proyecto 2006-2007 Inv. Responsable
Glaxo Smith-Kline frequency of the human papilloma virus (HPV) in invasive carcinomas of the uterine cervix in a population of Chilean women Roa, Jc Proyecto (2006)
PROYECTO BICENTENARIO=> TECHNOLOGICAL HEALTH RESEARCH CONSORTIUM. CITES-CHILE / / INVESTIGADOR / CONICYT-BANCO MUNDIAL. (CTE06) Proyecto 2006-2010 Inv. Principal
ESTUDIO DEL PATRON DE METILACION GENICO COMO FACTOR PRONOSTICO EN CARCINOMAS SUBSEROSOS POTENCIALMENTE CURABLES (pT2) DE LA VESICULA BILIAR. FONDECYT (1050603) Proyecto 2005-2007 Inv. Responsable
Estudio del Patrón de Metilación Génico como Factor Pronostico en Carcinomas subserosos Potencialmente Curables (pt2) de la Vesícula Biliar Roa, Juan Carlos Proyecto (2005)
MODULADORES DE LA RESPUESTA INFLAMATORIA DE LA MUCOSA GASTRICA ANTE LA INFECCION POR HELICOBACTER PYLORI=> INMUNIDAD, ESTRES OXIDATIVO Y CAPACIDAD CITOTOXICA BACTERIANA. FONDECYT (1020283) Proyecto 2002-2005 Coinvestigador(a)
CANCER DE LA VESICULA BILIAR ESTUDIO SOBRE SU DISEMINACION Y EL ROL DE LA PRESENCIA DE CELULAS MALIGNAS AISLADAS EN GANGLIOS LINFATICOS HIGADO Y MEDULA OSEA FONDECYT (1010523) Proyecto 2001-2003 Coinvestigador(a)
CLONALIDAD E INESTABILIDAD GENETICA EN LA CARCINOGENESIS DE LA VESICULA BILIAR=> INACTIVACION DEL GEN SUPRESOR DE TUMORES P53, MUTACION DE LOS GENES REPARADORES DE ADN GENOMICO HMLH1 Y HMSH2 E INESTABILIDAD FONDECYT (1991025) Proyecto 1999-2002 Inv. Responsable
Clonalidad e Inestabilidad Genética en la Carcinogenesis de la Vesícula Biliar: Inactivación del Gen Supresor de Tumores p53, Mutacion de los Genes Reparadores de ADN Genómico hMLH1 y hMSH2 e Inestabilidad Microsatelital en Lesiones Preneoplásicas y Carcinomas Avanzados. Roa, Juan Carlos Proyecto (1999)
PROLIFERACCION CELULAR Y APOPTOSIS EN CANCER GASTRICO=> EXPRESION DE PRODUCTOS DE ONCOGENES CELULARES ASOCIADOS A LA REGULACION DE LA CINETICA CELULAR Y SU RELACION CON MARCADORES DE PROLIFERACCION CELULAR Y PRONOSTICO FONDECYT (1950643) Proyecto 1995-1997 Coinvestigador(a)
Genetic and Immunological Research Center. Sanchez R.; Roa, Jc Proyecto (0)
Identification and validation of early diagnostic gallbladder cancer biomarkers in Chilean patients by quantitative proteomics. Roa, Juan Carlos; Garcia P.; Leal P.; Ferrecio, F; Tapia O. Proyecto (0)
Improving the production of phenylpropanoids with antioxidant activity in Highbush blueberry (Vaccinium corymbosum L.) using Methyl Jasmonate and UV-B radiation and its effect on gastric cancer chemoprevention Reyes, M; Roa, Jc Proyecto (0)
Initial Study of Gallbladder Cancer in Chile Ferrechio; Roa, Jc Proyecto (0)
Preclinical platform of xenograft models of metastatic human tissues for evaluating anticancer drug sensitivity. Montecinos, V.; Roa, Jc Proyecto (0)
Pyrosequencing platform for epigenetic and polymorphism research. Roa, Juan Carlos Proyecto (0)
Validation of MTOR metabolic pathway inactivation for gallbladder cancer targeted therapy. Roa, Juan Carlos Proyecto (0)


Exosomes in bile as potential pancreatobiliary tumor biomarkers Sagredo, AI; Sepulveda, SA; Roa, JC; Orostica, L Review ISI SCOPUS Translational Cancer Research (2017)
Emerging Role of miRNAs in the Drug Resistance of Gastric Cancer Riquelme, I; Letelier, P; Riffo-Campos, AL; Brebi, P; Roa, JC Review ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
The inflammatory inception of gallbladder cancer Espinoza, J.A; Bizama, C; Garcia P.; Ferreccio C.; Javle, M; Miquel, J.F; Koshiol, J; Roa, J.C Review ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2016)
Targeting specific molecular pathways holds promise for advanced gallbladder cancer therapy Bizama, C; Garcia P.; Espinoza, JA; Weber, H; Leal P.; Nervi, B; Roa, Jc Review ISI SCOPUS Cancer Treatment Reviews (2015)
Intracholecystic papillary tubular neoplasm of the gallbladder with microinvasive carcinoma Balci, S; Akkas G.; Roa, J.C; Adsay N.V. Review SCOPUS Pathology Case Reviews (2014)
[Detection of human papilloma virus infection in men]. [Diagnóstico de la infección por virus papiloma humano en el hombre.] Silva R.; LeÃ³n D.; Brebi P.; Ili C.; Roa, J.C; SÃ¡nchez R. Review SCOPUS REVISTA CHILENA DE INFECTOLOGIA (2013)
Human papillomavirus infection in men and its relation with cancer: Current status and prospectics Brebi P.; Hartley, R; Ili CG; Roa, Jc; Sanchez R. Review ISI SCOPUS Revista Internacional de Andrologia (2013)
Epigenetic alterations in preneoplastic and neoplastic lesions of the cervix Saavedra, K; Brebi P.; Roa, Jc Review ISI Clinical Epigenetics (2012)
Pericytes: New approaches in regenerative therapy, cerebrovascular pathology and cancer [Los pericitos: Nuevos enfoques en la terapia regenerativa, patología cerebrovascular y cáncer] Montiel-Eulefi E.; DÃaz L.B.; Leal P.; Roa, J.C; RisopatrÃ³n J.; Salazar, L.A.; Romero F.; SÃ¡nchez R. Review SCOPUS International Journal of Morphology (2011)
Alteraciones genéticas en lesiones preneoplásicas y neoplásicas de la vesícula biliar CASTILLO A, JONATHAN; GARCÍA M, PATRICIA; Roa S, Juan Carlos Review SCIELO REVISTA MEDICA DE CHILE (2010)
Appendiceal malignant tumors. Review of 84 cases Tapia O.; Manterola C.; Villaseca M.; Araya, JC; Guzman P.; Roa, Jc Review REVISTA CHILENA DE CIRUGIA (2010)
Genetic alterations in preneoplastic and neoplastic injuries of the gallbladder Castillo J.; Garcia P.; Roa, Jc Review REVISTA MEDICA DE CHILE (2010)
Gallbladder cancer: a morphological and molecular update Goldin, RD; Roa, Jc Review ISI SCOPUS Histopathology (2009)
Surface enhanced laser desorption/ionization (SELDI): proteomics technology and its application in oncology Espejel, F; Roa, Jc Review ISI MEDICINA CLINICA (2008)
p53 tumor supresor gene in digestive cancer Roa, Jc; Roa, I; Araya, JC; Villaseca, MA; Melo A.; Burgos, L. Review REVISTA MEDICA DE CHILE (2000)

426

Juan Roa

Chair

Pathology

Pontificia Universidad Catolica de Chile

santiago, Chile

Juan Araya

Pathologist

Anatomía Patológica

Hospital Dr. Hernan Henríquez Aravena

Temuco, Chile

Pablo Guzmán

Pathologist

Hospital Regional Dr. Hernán Henríquez Araven

Temuco, Chile

Priscilla Brebi

Profesor Asociado

Departamento de Anatomía Patológica.

Universidad de La Frontera

Temuco, Chile

Patricia García

Profesor Asistente

ANATOMIA PATOLOGICA

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Carmen Ili

Academico Asociado

Scientific and technological Bioresource Nucleus (BIOREN)

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

PAMELA LEAL

Profesor Asociado

Departamento de Ciencias Agronómicas y Recursos Naturales

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

Ismael Riquelme

Académico - Investigador

Ciencias de la Salud

UNIVERSIDAD AUTÓNOMA DE CHILE

Temuco, Chile

Carolina Bizama

Assistant professor

Department of Pathology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Sergio Munoz

Profesor Titular

Salud Publica

Universidad de La Frontera

Temuco, Chile

Helga Weber

Investigador

Vicerrectoría de Investigación y Post Grado

Universidad de la Frontera

Temuco, Chile

Carlos Manterola

Profesor Titular

Cirugía y Traumatología

Universidad de La Frontera

Temuco, Chile

fresia ferreccio

Full Professor, Director PhD Epidemiolgy Program

Public Health

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE FACULTAD DE MEDICINA, ESCUELA DE MEDICINA, DEPARTAMENTO DE SALUD PÚBLICA.

Santiago, Chile

Alejandra Andana

Asistente Investigación

Anatomía Patológica

Universidad de La Frontera

Temuco, Chile

Bruno Nervi

Associated Professor

Hematology - Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

Jaime Lopez

Asistente de Investigación

Anatomía Patologica

Universidad de La Frontera

Temuco, Chile

ALEJANDRO CORVALAN

Principal Investigator

Hematology and Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

Kurt Buchegger

Investigador Postdoctoral

Ciencias Básicas

Universidad de La Frontera

Temuco, Chile

René Hoffstetter

Leonardo Anabalón

PROFESOR ADJUNTO

FAC RECURSOS NATURALES

UNIVERSIDAD CATOLICA DE TEMUCO

TEMUCO, Chile

SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

Ramon Silva

Docente

Universidad Autonoma

Temuco, Chile

Pablo Letelier

Docente Planta Permanente (Instructor)

UNIVERSIDAD CATOLICA DE TEMUCO

temuco, Chile

Johanna Acevedo

Profesor asociado investigador

Instituto de Ciencias e Innovación en Medicina (ICIM)

Universidad del Desarrollo

Santiago, Chile

Lorena Rosa

PhD

Departamento de Patología

Pontificia Universidad Católica de Chile

Santiago, Chile

CLAUDIA BAMBS

PROFESORA ASOCIADA

SALUD PÚBLICA

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Nicolas Jarufe

Chief Digestive Surgery

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Tamara Viscarra

Investigador Postdoctoral

BIOREN

Universidad de La Frontera

Temuco, Chile

PABLO PEREZ

Profesor investigador

Programa de Comunicación en Cáncer

Universidad del Desarrollo

Santiago, Chile

Juan Miquel

Full Professor

Gastroenterology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Pablo Castro

JEFE DIVISION

DIVISION ENFERMEDADES CARDIOVASCULARES

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

Guillermo Díaz

Académico

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

María Villarroel

Médico Anátomo-Patólogo

Anatomía Patológica

Red de Salud UC Christus / Pontificia Universidad Católica de Chile

Santiago, Chile

Santiago Sepúlveda

Profesional Tecnólogo Médico

Anatomía Patológica

Pontificia Universidad Católica de Chile

Santiago, Chile

Laura Huidobro

Encargada Investigación

Ciencias Preclínicas

Universidad Católica del Maule

Talca, Chile

Juan Orellana

Asistente A

Salud Pública

Universidad de La Frontera

Temuco, Chile

Francisco Mucientes

Jefe de Sección

Especialidades

Universidad de Concepción

Concepción, Chile

BARBARA MORA

Profesor Investigador

Facultad de Ciencias de la Salud

Universidad Autónoma de Chile

Temuco, Chile

Daniela Parada

Asistente de investigación

Programa Disciplinario de Inmunología

Universidad de Chile

Santiago, Chile

Daniela León

Investigador Postdoctoral

Universidad de La Frontera

Temuco, Chile

Claudia Foerster

Associate Professor

Institute of Agri-food, Animal and Environmental Sciences

Universidad de O'Higgins

San Fernando, Chile

Arnoldo Riquelme

Profesor titular

Gastroenterología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE GASTROENTEROLOGÍA

Santiago, Chile

jose valbuena

Associate Professor

Anatomic Pathology

PONTIFICIA UNIVERSIDAD CATOLICA. FACULTAD DE MEDICINA/ESCUELA DE MEDICINA/ DEPARTAMENTO DE ANATOMÍA PATOLÓGICA

santiago, Chile

Jorge Sapunar

Head of Unit

Investigación del Cáncer

Instituto Oncológico Fundación Arturo López Pérez

Santiago, Chile

IVAN GALLEGOS

PATHOLOGIST, LABORATORY DIRECTOR

PATHOLOGY

HOSPITAL CLINICO DE UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Glauben Landskron

Academic Researcher

Escuela de Medicina

Universidad Finis Terrae

Santiago, Chile

Claudia Heider

Profesor Clinico Asistente

Otorrinolaringología

Pontificia Universidad Católica de Chile

Santiago, Chile

Gonzalo De Toro

MEDICO ANATOMOPATOLOGO

HOSPITAL DE PUERTO MONTT - LABORATORIO DE ANATOMIA PATOLOGICA Y BIOLOGIA MOLECULAR

PUERTO MONTT, Chile

Sergio Vargas

Investigador

Hematología-Oncología

Pontificia Universidad Católica de Chile

Santiago, Chile

Gareth Owen

Profesor Titular

Fisiologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Patricia Macanas

Profesor Asistente Adjunto

Hematology Oncology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

223543432, Chile

Hector Contreras

Academico

Oncologia Basico Clinica

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FISIOLOGÍA Y BIOFÍSICA

Santiago, Chile

Michel Abanto

Académico

Universidad de La Frontera

Temuco, Chile

Klaus Puschel

Full Professor

Family Medicine

FACULTAD MEDICINA PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Lorena Lobos

Principal Investigator-Associate Proffesor

Facultad of Medicine - Clinic Alemana

Universidad Del Desarrollo

santiago, Chile

JOSE SANTOS

Full Professor

Department of Nutrition, Diabetes and Metabolism

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Marcelo Lopez

Profesor Titular

Infectologia e Inmunologia Pediatrica

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Ignacio Jofré

Postdoctoral Researcher

Departamento de Ciencias Químicas

Universidad de La Frontera

Temuco, Chile

Rodrigo Gutierrez

Full Professor

Molecular Genetics & Microbiology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Paulina Orellana

Coordinadora traslacional

Universidad de Chile

Santiago, Chile

María Gleisner

INVESTIGADORA

ICBM

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Eduardo Sagredo

Alexis Kalergis

Full Professor

Microbiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

Alfonso Hernández

Profesor Asistente

Departamento de Procesos Diagnósticos y Evaluación

UNIVERSIDAD CATOLICA DE TEMUCO

Temuco, Chile

Patricio Smith

Profesor Asociado

Odontología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Evelyn Pardo

Investigadora Independiente

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

SANTIAGO , Chile

Christopher Holmes

Estudiante de doctorado

Ingeniería Biomédica

Pontificia Universidad Catolica de Chile

Santiago, Chile

Claudia Oyanadel

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Mercedes López

Profesora Asociada

Instituto de Ciencias Biomédicas

Universidad de chile

Santiago, Chile

Leda Guzman

Profesor Adjunto

Instituto de Química

Pontificia Universidad Católica de Valparaíso

Valparaíso, Chile

Rodrigo Fuentealba

Postdoctoral Research Associate

Departamento de Inmunología Clínica y Reumatología / Facultad de Medicina

Pontificia Universidad Católica

Santiago, Chile

Claudia Riedel

Full Professor

Life Sciences

Universidad Andres Bello

Santiago, Chile

Karen Bohmwald

Académico Investigador

Universidad Autónoma de Chile

Santiago, Chile

Fermín González

Profesor Asociado

Odontología Conservadora

Universidad de Chile

Santiago, Chile

Felipe Benavente

Investigador Postdoctoral

Pontificia Universidad Católica de Chile

Santiago, Chile

CARMEN ASTETE

Profesor titular

ICIM

Fac de Medicina. Universidad del Desarrollo

Santiago, Chile

Miguel Allende

Director

Biología

FACULTAD DE CIENCIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

Zully Pedrozo

Associated Professor

Physiology and Biophysical

Universidad de Chile

SANTIAGO DE CHILE, Chile

Fernando Romero

Profesor JC, asociado

Ciencias Preclínicas

Universidad de La Frontera

Temuco, Chile

Fernando Sepúlveda

Representante Legal

NeuroLabs

Talcahuano, Chile

Evelyn Jara

Docente/Investigador

Ciencias Básicas

Universidad Santo Tomás

Temuco, Chile

Jorge Farias

Full Professor

Chemical Engineering

Universidad de La Frontera

Temuco, Chile

Vanessa Van De Wyngard

Investigadora

Escuela de Medicina

Pontificia Universidad Católica de Chile

Santiago, Chile

Jennie Risopatrón

Académico y Director del CEBIOR

Ciencias Básicas

Universidad de La Frontera

Temuco, Chile

Luis Salazar

Profesor Titular

Ciencias Básicas

Universidad de La Frontera

Temuco, Chile

Juan Tapia

Profesor Asociado

UNIVERSIDAD DE TALCA

Talca, Chile

Wilda Olivares

Bioquímico-Asistente en investigación y Coordinadora de Proyectos de Investigación.

hematologia oncologia

Pontificia Universidad Católica de Chile

santiago, Chile

Flavio Salazar

Profesor titular

Instituto de ciencias biomédicas

Universidad de Chile

SANTIAGO, Chile

Eduardo Pérez

Profesor Investigador Asociado

Centro de Genética y Genómica, Facultad de Medicina Clínica Alemana

Universidad del Desarrollo

Santiago, Chile

Doris Menzel

Bioquímico

Anatomía Patológica

Universidad de La Frontera

Temuco, Chile

Mauricio Pinto

Investigador

STORM SPA

Santiago, Chile

Vinicius Ramos Henriques

Associate Professor

Advanced Center for Chronic Diseases - ACCDiS

Univesidad de Chile

Santiago, Chile

Juan Arab

Assistant Professor

Gastroenterologia

Pontificia Universidad Católica de Chile

Santiago, Chile

Juan Calderon

Investigador

Facultad de Medicina

Universidad del Desarrollo

Santiago, Chile

Claudia Metz

Docente Investigador

Universidad San Sebastián

Santiago, Chile

Ricardo Hartley

Investigador

Instituto de Investigación y Postgrado

Universidad Central de Chile

Santiago, Chile

Francisco Barrera

Profesor Asociado

Gastroenterología

Pontificia Universidad Católica de Chile

Santiago, Chile

Carlos Salomón

Academic

University of Concepcion

Concepcion, Chile

Álvaro Passi

PhD student

Research Department of Epidemiology & Public Health

University College London

London, Reino Unido

Arnoldo Riquelme

Director UDA Ciencias de la Salud (Carreras de Nutrición y dietética, Fonoaudiología y Kinesiología)

Gastroenterología

Pontificia Universidad Católica de Chile

Santiago, Chile

María Oróstica

Alfredo Criollo

Associated Professor

Research Institute in Dental Sciences

Facultad de Odontología, Universidad de Chile

Santiago, Chile

Valeria Garrido

Investigador Postdoctoral

Advanced Center for Chronic Disease

Universidad de Chile

Santiago, Chile

Victor Aliaga

Postdoctorante

Universidad de O'Higgins

Santiago, Chile

Rolando de la Cruz

Associate Professor

Faculty of Engineering and Sciences

Universidad Adolfo Ibáñez

Peñalolén, Santiago, Chile

Pablo Toro

Profesor Asociado

Psiquiatría

Pontificia Universidad Católica de Chile

Santiago, Chile

Octavio Orellana

Investigador Postdoctoral

ICBM

Universidad de Chile

Santiago, Chile

SANDRA CORTES

ASSOCIATED PROFESSOR

PUBLIC HEALTH

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Alejandra Vives

DEPTO. SALUD PÚBLICA, UNIVESIDAD CATÓLICA DE CHILE

Santiago, Chile

Hugo Verdejo

Profesor Asociado

División de Enferemedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

Ignacio Wichmann

Assitant Professor

Obstetrics

Pontificia Universidad Católica de Chile

Santiago, Chile

Sebastián Illanes

professor, Director of Reproductive Biology Laboratory

Medicine

UNIVERSIDAD DE LOS ANDES

Santiago, Chile

MARCO ARRESE

FULL PROFESSOR

GASTROENTEROLOGY

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Cristian Alvarez

Profesor Asistente

Escuela de Medicina Veterinaria

Pontificia Universidad Católica de Chile

Zurich, Chile

Rene Baudrand

Profesor Asociado

Endocrinología

Pontificia Universidad Católica de Chile

Santiago, Chile

Oslando Padilla

Estadístico

Salud Pública

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Daniel Cabrera

Investigador Adjunto

Gastroenterología

Pontificia Universidad Catolica de Chile

santiago, Chile

Margarita Pizarro

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Francisco Aguayo

Profesor Asociado

Programa de Virología, Instituto de Ciencias Biomédicas (ICBM)

Universidad de Chile

Santiago, Chile

Eleodoro Riveras

Investigador postdoctoral

Instituto de Biologia Integrativa, Ibio

Santiago, Chile

María Marchant

Profesor Postdoctoral

Química

Pontificia Universidad Católica de Valparaíso

Valparaiso, Chile

Nicolás Saavedra

Profesor Asociado

Departamento de Ciencias Básicas

Universidad de La Frontera

Temuco, Chile

Hugo Marsiglia

Director Relaciones Médicas Internacionales

Fundación Arturo López Pérez

Santiago, Chile

Luis Aguayo

Full Professor

Department of Physiology

Universidad de Concepcion

Concepcion, Chile

Viviana Montecinos

Assistant Professor

Hematology Oncology

Pontificia Universidad Catolica de Chile

Santiago, Chile

Gonzalo Latorre

Médico Internista

Medicina Interna

Pontificia Universidad Católica de Chile

Santiago, Chile

Rodrigo Morales

Postdoctoral researcher

Dept. of Medicine Solna (MedS)

Karolinska Institutet

Stockholm, Suecia

MARIA REYES

Profesor investigador

Biología

Universidad Autónoma de Chile

TEMUCO, Chile

Pontificia Universidad Católica de Chile

Santiago, Chile

Jose Martínez

Investigador

ICIM

Universidad del Desarrollo

LAS CONDES, Chile

Francisca Sepúlveda

PhD(c)

Instituto de Ciencias e Innovación en Medicina

Universidad del Desarrollo

Santiago, Chile

Javiera Obreque

Investigadora Postdoctoral

CECAN - PUC

Santiago, Chile

Erik Morales

Profesor Auxiliar

Ciencias Preclínicas

UNIVERSIDAD CATÓLICA DEL MAULE

Talca, Chile

Jaime Madariaga

ASSOCIATE PROFESSOR

MEDICAL SPECIALTIES

UNIVERSITY OF CONCEPCION

CONCEPCION, Chile

Juan Carlos Roa Strauch

Líneas de Investigación

Educación

Medical Doctor, UNIVERSIDAD DE LA FRONTERA. Chile, 1991

Oncologia molecular, Centro de estudios sanitarios de Europa. España, 2012

Especialista en Anatomia patologica, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1995

Fellowship in molecular biology, LOUISIANA STATE UNIVERSITY. Estados Unidos, 1999

Experiencia Académica

Assistant Professor Part Time

Associate Professor Part Time

Full Professor Full Time

Full professor Full Time

Experiencia Profesional

Professor Part Time

Surgical Pathologist Full Time

Surgical Pathologist Full Time

Professor , Chair Department of pathology Full Time

Formación de Capital Humano

Difusión y Transferencia

Premios y Distinciones

Scientific Productivity Award

Chilean Gastroenterology Congress Award

Chilean Academy of Medicine Award

Scientific Productivity Award

Gonzalo Tolosa Award

Cautin Medical Society Award

EXPERTSCAPE

Mejor Investigador. Escuela Medicina

Premio Investigación médica 2024

Expertscape

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