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Juan Carlos Prieto Domínguez

Profesor Titular

Universidad de Chile

Santiago, Chile

Enfermedades cardiovasculares, Farmaco-epidemiología, Estatinas, Isquemia-reperfusión miocárdica, Infarto agudo de miocardio, Estrés oxidativo, Conducción de ensayos clínicos

Médico cirujano, UNIVERSIDAD DE CHILE. Chile, 1983
Cardiólogo, CONACEM. Chile, 1994
Farmacólogo Clínico, UNIVERSIDAD DE CHILE. Chile, 1997

Profesor titular Full Time

UNIVERSIDAD DE CHILE

Facultad de Medicina

Santiago, Chile

1990 - A la fecha

Profesor titular Full Time

Universidad de Chile

Santiago, Chile

1990 - A la fecha
Cardiólogo Clínico Part Time

Hospital Clínico Universidad de Chile

Santiago, Chile

1990 - A la fecha

Presidente Sociedad Chilena Cardiología y Cirugía Cardiovascular

SOCIEDAD CHILENA DE CARDIOLOGIA Y CIRUGIA CARDIOVASCULAR

Chile, 2018

Presidente electo SOCHICAR


Involvement of NO in Antinociception of NSAIDS in Murine Formalin Hind Paw Assay Noriega V.; Miranda, H. F.; Prieto, J. C.; Sotomayor-ZÃ¡rate R.; Sierralta F. Article ISI SCOPUS Drug Research (2020)
Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome: ODYSSEY OUTCOMES Trial Jukema, J. W.; Szarek M.; Zijlstra L.E.; de Silva H.A.; Bhatt, D. L.; Bittner V.A.; Diaz R.; Edelberg J.M.; Goodman, S. G.; Hanotin C.; Harrington, R. A.; Karpov Y.; Moryusef A.; Pordy R.; Prieto, J. C.; Roe, M. T.; White, H. D.; Zeiher A.M.; Schwartz G.G.; Steg, P. G.; ODYSSEY OUTCOMES Committees and Investigators Article SCOPUS Journal of the American College of Cardiology (2019)
Interleukin-1beta in synergism gabapentin with tramadol in murine model of diabetic neuropathy Miranda, H. F.; Poblete P.; Sierralta F.; Noriega V.; Prieto, J. C.; Zepeda R.J. Article ISI SCOPUS INFLAMMOPHARMACOLOGY (2019)
Nitric Oxide and Opioids Involvement in Isobolographic Nsaids Antinociception Miranda, H. F.; Noriega V.; Sierralta F.; Poblete P.; Aranda N.; Prieto, J. C. Article WOS-ESCI SCOPUS Drug Research (2019)
Non-steroidal Anti-inflammatory Drugs in Tonic, Phasic and Inflammatory Mouse Models Miranda, H. F.; Noriega V.; Sierralta F.; Poblete P.; Aranda N.; Prieto, J. C. Article WOS-ESCI SCOPUS Drug Research (2019)
Pharmacological interaction between NSAIDS with clomipramine and risperidone in mice visceral pain Vargas C.G.; Miranda, H. F.; Sierralta F.; Noriega V.; Prieto, J. C. Article ISI SCOPUS DRUG DEVELOPMENT RESEARCH (2019)
Stroke in Patients With Peripheral Artery Disease: Insights From the EUCLID Study Kolls B.J.; Sapp S.; Rockhold F.W.; Jordan J.D.; Dombrowski K.E.; Fowkes F.G.R.; Mahaffey, K. W.; Berger J.S.; Katona B.G.; Blomster J.I.; Norgren L.; Abramson B.L.; Leiva-Pons J.L.; Prieto, J. C.; Sokurenko G.; Hiatt W.R.; Jones W.S.; Patel M.R. Article ISI SCOPUS STROKE (2019)
Antinociception induced by rosuvastatin in murine neuropathic pain Miranda, HF; Sierralta F.; Aranda N.; Poblete P.; Castillo, RL; Noriega, V; Prieto, JC Article ISI SCOPUS PHARMACOLOGICAL REPORTS (2018)
Synergism between gabapentin–tramadol in experimental diabetic neuropathic pain Miranda, H. F.; Sierralta F.; Aranda N.; Poblete P.; Noriega V.; Prieto, J. C. Article ISI SCOPUS Fundamental and Clinical Pharmacology (2018)
Antinociceptive interaction of gabapentin with minocycline in murine diabetic neuropathy Miranda H.F.; Sierralta F.; Jorquera V.; Poblete P.; Prieto J.C.; Noriega V. Article ISI SCOPUS INFLAMMOPHARMACOLOGY (2017)
Effects of a novel ascorbate-based protocol on infarct size and ventricle function in acute myocardial infarction patients undergoing percutaneous coronary angioplasty Ramos, Cristóbal; Brito, Roberto; González-Montero, Jaime; Valls, Nicolás; Gormaz, Juan G.; Prieto, Juan C.; Aguayo, Rubén; Puentes, Ángel; Noriega, Viviana; Pereira, Gonzalo; Palavecino, Tamara; Rodrigo, Ramón Article ISI SCOPUS ARCHIVES OF MEDICAL SCIENCE (2017)
Amelioration of persistent left ventricular function impairment through increased plasma ascorbate levels following myocardial infarction Valls, N; Gormaz, JG; Aguayo, R; González, J; Brito, R; Hasson, D; Libuy, M; Ramos, C; Carrasco, R; Prieto, JC; Dussaillant, G; Puentes, A; Noriega, V; Rodrigo, R Article ISI SCOPUS REDOX REPORT (2016)
Antinociceptive Interaction of Tramadol with Gabapentin in Experimental Mononeuropathic Pain Miranda, HF; Noriega, V; Prieto, JC; Zanetta, P; Castillo, R; Aranda, N; Sierralta, F Article ISI SCOPUS BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2016)
Características, manejo y evolución intrahospitalaria de usuarios de drogas ilícitas con infarto agudo del miocardio Jorge Bartolucci; Carolina Nazzal N.; Fernando J. Verdugo; Juan Carlos Prieto; Pablo Sepúlveda; Ramon Corbalan Article SCIELO SCOPUS REVISTA MEDICA DE CHILE (2016)
Pharmacological profile of dexketoprofen in orofacial pain Miranda, HF; Sierralta, F; Aranda, N; Noriega, V; Prieto, JC Article ISI SCOPUS PHARMACOLOGICAL REPORTS (2016)
Antinociceptive Synergism of Gabapentin and Nortriptyline in Mice with Partial Sciatic Nerve Ligation Miranda, HF; Noriega V.; Zepeda, R.; Zanetta P.; Prieto-Rayo, J; Prieto, JC; Sierralta F. Article ISI SCOPUS Pharmacology (2015)
Involvement of nitridergic and opioidergic pathways in the antinociception of gabapentin in the orofacial formalin test in mice Miranda, H. F.; Sierralta F.; Lux S.; Troncoso R.; Ciudad N.; Zepeda, R.; Zanetta P.; Noriega V.; Prieto, J. C. Article ISI SCOPUS PHARMACOLOGICAL REPORTS (2015)
Isobolographic analysis of the opioid-opioid interactions in a tonic and a phasic mouse model of induced nociceptive pain Miranda, HF; Noriega V.; Zanetta P.; Prieto, JC; Prieto-Rayo, JC; Aranda N.; Sierralta F. Article ISI SCOPUS JOURNAL OF BIOMEDICAL SCIENCE (2014)
The effectiveness of antioxidant vitamins C and E in reducing myocardial infarct size in patients subjected to percutaneous coronary angioplasty (PREVEC Trial): study protocol for a pilot randomized double-blind controlled trial Rodrigo R.; Hasson D.; Prieto, JC; DUSSAILLANT, G; Ramos C.; Leon, L.; Garate, J; Valls, N.; Gormaz, JG Article ISI SCOPUS TRIALS (2014)
Isobolographic analysis in mice of the interaction of gabapentin and nortriptyline in relieving orofacial pain Miranda, H. F.; Noriega V.; Zanetta P.; Prieto, J. C. Article ISI SCOPUS JOURNAL OF ORAL & FACIAL PAIN AND HEADACHE (2013)
Isobolographic analysis in mice of the interaction of gabapentin and nortriptyline in relieving orofacial pain Miranda HF, Noriega V; Zanetta P, Prieto JC Article Journal Orofacial Pain (2013)
Systemic synergism between codeine and morphine in three pain models in mice  Miranda HF, Noriega V; Zepeda R, Sierralta F Article Pharmacological Reports (2013)
Effect of Carvedilol and Nebivolol on Oxidative Stress-related Parameters and Endothelial Function in Patients with Essential Hypertension Zepeda R.J.; Castillo R.; Rodrigo R.; Prieto, J. C.; Aramburu, I; Brugere, S; Galdames K.; Noriega V.; Miranda, H. F. Article ISI SCOPUS Basic & clinical pharmacology & toxicology (2012)
Previous administration of naltrexone did not change synergism between paracetamol and tramadol in mice Miranda, H. F.; Noriega V.; Prieto, J. C. Article ISI SCOPUS Pharmacology Biochemistry and Behavior (2012)
Synergism Between Fentanyl and Tramadol in Tonic Inflammatory Pain: the Orofacial Formalin Test Miranda, H. F.; Noriega V.; Zepeda R.J.; Sierralta F.; Prieto, J. C. Article ISI SCOPUS Inflammation (2012)
Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes Tricoci, P.; Huang Z.; Held, C; Moliterno D.J.; Armstrong P.W.; Van de Werf, F; White, H. D.; Aylward P.E.; Wallentin L.; Chen E.; Lokhnygina, Y; Pei, J; Leonardi S.; Rorick T.L.; Kilian A.M.; Jennings L.H.K.; Ambrosio G.; Bode, C; Cequier, A; Cornel J.H.; Díaz R; Erkan A.; Huber K.; Hudson M.P.; Jiang L.; Jukema, J. W.; Lewis B.S.; Lincoff A.M.; Montalescot, G; NICOLAU J.C.; Ogawa, H.; Pfisterer, M; Prieto, J. C.; Ruzyllo, W; Sinnaeve P.R.; Storey R.F.; Valgimigli, M; Whellan D.J.; Widimsky P.; Strony, J; Harrington, R. A.; Mahaffey, K. W. Article ISI SCOPUS New England Journal of Medicine (2012)
Antinociception and Anti-Inflammation Induced by Simvastatin in Algesiometric Assays in Mice Miranda, HF; Noriega V.; Olavarria, L.; Zepeda RJ; Sierralta F.; Prieto, JC Article ISI SCOPUS Basic & clinical pharmacology & toxicology (2011)
Antinociception induced by atorvastatin in different pain models Garcia, GG; Miranda, HF; Noriega V.; Sierralta F.; Olavarria, L.; Zepeda RJ; Prieto, JC Article ISI SCOPUS Pharmacology Biochemistry and Behavior (2011)
Interaction between dexibuprofen and dexketoprofen in the orofacial formalin test in mice Miranda, HF; Noriega V.; Sierralta F.; Prieto, JC Article ISI SCOPUS Pharmacology Biochemistry and Behavior (2011)
Synergism between dexketoprofen and meloxicam in an orofacial formalin test was not modified by opioid antagonists Gonzalez, Claudia; Zegpi, Carlos; Noriega, Viviana; Prieto, Juan C.; Miranda, Hugo F. Article ISI PHARMACOLOGICAL REPORTS (2011)
Synergism between COX-3 inhibitors in two animal models of pain Muñoz J; Navarro, C.; Pinardi, G; Sierralta F.; Prieto, J. C.; Miranda, H. F.; Noriega V. Article SCOPUS Inflammopharmacology (2010)
(TTA)n Polymorphism in 3-Hydroxy-3-Methylglutaryl-Coenzyme A and Response to Atorvastatin in Coronary Artery Disease Patients Noriega V.; Pennanen C.; Sanchez, MP; Chiong M.; Llancaqueo, M; Lavandero S.; Prieto, JC Article ISI SCOPUS BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2009)
Effects of tramadol and dexketoprofen on analgesia and gastrointestinal transit in mice Miranda, HF; Puig, MM; Romero, MA; Prieto, JC Article ISI SCOPUS FUNDAMENTAL CLINICAL PHARMACOLOGY (2009)
Synergism between NSAIDs in the orofacial formalin test in mice Miranda, HF; Sierralta F.; Prieto, G. Article ISI SCOPUS PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2009)
The Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRA.CER) trial: study design and rationale Harrington, RA; Van de Werf, F; Armstrong, PW; Aylward, P; Veltri, E; Mahaffey, KW; Moliterno, DJ; Strony, J; Wallentin L.; White, HD; Díaz R; Huber K.; Nicolau, JC; Prieto, JC; Isaza, D; Widimsky P.; Grande, P; Nieminen, M; Montalescot, G; Bode, C; Wong, L; Ofner, P; Lewis, BS; Ambrosio G.; Valgimigli, M; Ogawa, H.; Yamaguchi, J; Jukema, JW; Cornel, JH; Nordrehaug, JE; Ruzyllo, W; Providencia, L; Tan, HC; Dalby, A; Seung-Jung, P; Betriu, A; Cequier, A; Held, C; Pfisterer, M; Ming-Fong, C; Timurkaynak, T; Storey, RF; Chen E.; Hudson, MP; Lincoff, AM; Morrow, DA; Tricoci, P.; Whellan, D Article ISI AMERICAN HEART JOURNAL (2009)
Isobolographic analysis of multimodal analgesia in an animal model of visceral acute pain Miranda, HF; Prieto, JC; Puig, MM; Pinardi, G Article ISI SCOPUS PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2008)
Lack of effect of atorvastatin or pravastatin on the endothelium-dependent relaxation in segments of human vessels Prieto, J. C.; Zamorano J.; Larrain, E; Castillo R.; Espinoza J.; Pinardi, G; Zepeda R.J.; Miranda, H. F. Article SCOPUS International Journal of Pharmacology (2008)
Mortalidad intrahospitalaria en hombres y mujeres según terapias de reperfusión en infarto agudo del miocardio con supradesnivel del ST Prieto, Juan Carlos; Sanhueza, Consuelo; Martínez, Nicolás; Nazzal, Carolina; Corbalán Ramón; Cavada, Gabriel; Lanas, Fernando; Bartolucci, Jorge; CAMPOS, PABLA Article SCIELO REVISTA MEDICA DE CHILE (2008)
The impact of Chilean health reform in the management and mortality of ST elevation myocardial infarction (STEMI) in Chilean hospitals Nazzal N C, Campos T P, Corbalán H R, Lanas Z F, Bartolucci J J, Sanhueza C P, Cavada Ch G, Prieto D JC Article REVISTA MEDICA DE CHILE (2008)
Dexketoprofen-induced antinociception in animal models of acute pain: Synergy with morphine and paracetamol Miranda, HF; Puig, MM; Dursteler, C; Prieto, JC; Pinardi, G Article ISI SCOPUS NEUROPHARMACOLOGY (2007)
Influencia del sistema nitridérgico en la respuesta contráctil a fenilefrina de anillos de vasos usados en revascularización coronaria Prieto, Juan C.; Pinardi, Gianni; Zamorano, Jaime; Larrain, Ernesto; Bermúdez, Cristian; Castillo, Rodrigo; Cisternas, Verónica; Miranda, Hugo F. Article SCIELO REVISTA MEDICA DE CHILE (2007)
Modification of phenylephrine induced contraction of human vessel rings by L-arginine and L-arginine methyl ester Prieto JC, Pinardi G, Zamorano J, Larrain E, Bermudez C, Castillo R, Cisternas V, Miranda HF Article (2007)
Synergism between paracetamol and nonsteroidal anti-inflammatory drugs in experimental acute pain Miranda, HF; Puig, MM; Prieto, JC; Pinardi, G Article ISI SCOPUS PAIN (2006)
Utilidad de la terapia trombolítica con estreptokinasa a dosis baja en infarto agudo del miocardio Raffo G, Carlos; Bartolucci J, Jorge; Corbalán H, Ramón; Aninat H, Mauricio; Torres, H. Humberto; Prieto D, Juan Carlos; Lanas Z, Fernando; Chávez S, Eduardo; Cumsille G, Francisco; Nazzal N, Carolina Article SCIELO REVISTA MEDICA DE CHILE (2006)
Analgesic synergism between intrathecal morphine and cyclooxygenase-2 inhibitors in mice Pinardi, G; Prieto, JC; Miranda, HF Article ISI SCOPUS PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2005)
Hypotensive effect of dopamine: synergism induced by fenoldopam or levodopa Prieto, JC; Quevedo, M.; Miranda, HF; Pinardi, G Article ISI SCOPUS Acta Cardiologica (2005)
Resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamiento Corbalán H, Ramón; Nazzal N, Carolina; Eggers R, Germán; Bartolucci J, Jaime; Prieto D, Juan Carlos; Alcaino I, Milton; Stockins F, Benjamín; Campos P, Pabla; Dapelo A, Alejandro Article ISI SCIELO REVISTA MEDICA DE CHILE (2004)
Reduction of Myocardial Infarction Mortality in Chilean Hospitals Corbalan R, Nazzal C, Prieto JC, Chavez E et al. Article REVISTA MEDICA DE CHILE (2002)
Cardiovascular risk factors in middle-age women with acute coronary syndromes Blümel JE, Prieto JC, Leal T, Cruz MN, Gallardo L Article (2001)
Changes in the patterns of drug prescription for acute myocardial infarct. Comparison of 2 periods Prieto JC, Corbalan R, Nazzal C, Chavez E et al. Article REVISTA MEDICA DE CHILE (2001)
Safety profile of statins Prieto, JC Article REVISTA MEDICA DE CHILE (2001)
Isobolographic analysis of the interaction between fenoldopam and levodopa on arterial blood pressure of the rat Quevedo, M.; Prieto, JC; Miranda, HF; Pinardi, G Article ISI SCOPUS JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2000)
Bedside markers of coronary artery patency and short-term prognosis of patients with acute myocardial infarction and thrombolysis Corbalan, R; Prieto, JC; Chavez, E; Nazzal, C; Cumsille, F; Krucoff, M Article ISI AMERICAN HEART JOURNAL (1999)
The beta 2 receptor plays a role in the hypotensive effect of L-dopa. Quevedo M, Prieto JC, Pérez-Olea J Article ACTA PHYSIOLOGICA PHARMACOLOGICA ET THERAPEUTICA LATINOAMERICANA (1995)
Surrogate end points: the case of trials on coronary atherosclerotic plaque regression Marchioli R, Prieto JC, Tognoni G Article CLINICAL TRIALS AND META-ANALYSIS (1994)


Differences in treatment and in-hospital mortality of acute myocardial infarction patients in public and private hospitals in Chile before and after healthcare guarantees Nazzal C.; Corbalan, R; Frenz, P; Sepúlveda P.; Prieto, J. Abstract ISI EUROPEAN HEART JOURNAL (2013)


PREVENTION OF REPERFUSION DAMAGE ASSOCIATED WITH PERCUTANEOUS CORONARY ANGIOPLASTY FOLLOWING ACUTE MYOCARDIAL INFARCTION FONDECYT (1120594) Proyecto 2012-2015 Investigador(a)


Cardioprotection against ischaemia/reperfusion by vitamins C and E plus n-3 fatty acids: molecular mechanisms and potential clinical applications Rodrigo R.; Prieto, JC; Castillo R. Review ISI SCOPUS Clinical Science (2013)

Juan Prieto

Profesor Titular

Programa de Farmacología Molecular y Clínica

Universidad de Chile

Santiago, Chile

Viviana Noriega

Profesional

Hospital Clinico Universidad de Chile

Santiago, Chile

Ramiro Zepeda

Academico

Farmacologia y neurociencia

universidad de Chile

santiago, Chile

angelo ramos

medico radiologo

centro imagenolgia

Hospital Clinico Universidad De Chile

santiago, Chile

Ramón Rodrigo

PROFESOR TITULAR

INSTITUTO DE CIENCIAS BIOMÉDICAS

UNIVERSIDAD DE CHILE, FACULTAD DE MEDICINA, INSTITUTO DE CIENCIAS BIOMÉDICAS, PROGRAMA DE FARMACOLOGÍA MOLECULAR Y CLÍNICA

Santiago, Chile

Rubén Aguayo

Director de Departamento Medicina Interna Occidente

Departamento de Medicina Interna Occidente

Universidad de Chile

Santiago, Chile

Rodrigo Castillo

Profesor Asistente

Medicina Interna Oriente

University of Chile

Santiago, Chile

Mario Chiong

Profesor

Departamento de Bioquímica y Biología Molecular

Universidad de Chile

Santiago, Chile

Jaime Gonzalez

Académico

Departamento de Oncología Básico Clínico

Universidad de Chile

Independencia, Chile

Pablo Sepúlveda

Cardiólogo Intervencionista

División de Enfermedades Cardiovasculares

Pontificia Universidad Católica de Chile

Santiago, Chile

Carolina Nazzal

Profesor Asociado

Instituto de Salud Poblacional

Universidad de Chile

Santiago, Chile

RODRIGO CARRASCO

Miembro titular

Sociedad Chilena de Cardiologia y Cirugia Cardiovascular

Oberageri, Suiza

Gonzalo Pereira

Médico radiólogo

Radiología

Hospital Clinico Universidad de Chile

Santiago, Chile

Matias Libuy

RESEARCH ASSISTANT

Programa de Políticas, Sistemas y Gestión en Salud

UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Nicolás Valls

Medico Anestesiologo

Anestesiología y medicina perioperatoria

Hospital CLinico Universidad de Chile

Santiago, Chile

Fernando Verdugo

Cardiologo

Cardiologia

Hospital del Salvador

Santiago, Chile

Ramón Sotomayor

Full Professor

Institute of Physiology

UNIVERSIDAD DE VALPARAÍSO, FACULTAD DE CIENCIAS, DEPARTAMENTO DE FISIOLOGÍA

Valparaíso, Chile

Fernando Lanas

Profesor titular

Medicina Interna

UNIVERSIDAD DE LA FRONTERA

Temuco, Chile

Gabriel Cavada

Académico, Jefe de Programa

Instituto de Salud Poblacional

Universidad de Chile

Santiago, Chile

Ramon Corbalan

Director

Division of Cardiovascular Diseases

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

María Sánchez

Académica

Biología

Universidad de Santiago de Chile

Santiago, Chile

SERGIO LAVANDERO

Director

Advanced Center for Chronic Diseases (ACCDiS)

UNIVERSIDAD DE CHILE, FAC CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

Juan Carlos Prieto Domínguez

Líneas de Investigación

Educación

Médico cirujano, UNIVERSIDAD DE CHILE. Chile, 1983

Cardiólogo, CONACEM. Chile, 1994

Farmacólogo Clínico, UNIVERSIDAD DE CHILE. Chile, 1997

Experiencia Académica

Profesor titular Full Time

Experiencia Profesional

Profesor titular Full Time

Cardiólogo Clínico Part Time

Premios y Distinciones

Presidente Sociedad Chilena Cardiología y Cirugía Cardiovascular

Article (55)

Abstract (1)

Proyecto (1)

PREVENTION OF REPERFUSION DAMAGE ASSOCIATED WITH PERCUTANEOUS CORONARY ANGIOPLASTY FOLLOWING ACUTE MYOCARDIAL INFARCTION

Review (1)