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Jaime Agustin Gutierrez Perez

Associate Professor and Researcher

Universidad San Sebastián

Santiago, Chile

Pregnancy Syndromes, Placenta, Preeclampsia, Cell commitment and Differentiation; Trophoblast biology.

Molecular and Cellular Biology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2009
Molecular and Cellular Biology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007
Biochemist, Pontificia Universidad Católica de Chile. Chile, 2005

Associate Researcher Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Faculty of Biological Sciences

Santiago, Chile

2010 - 2013
Academic - Main Researcher Full Time

Universidad San Sebastian

Health Sciences

Santiago, Chile

2014 - A la fecha

Researcher Other

Pontificia Universidad Católica de Chile

Santiago, Chile

2005 - 2009
Postdoctor Proyecto Anillos ACT-73 Full Time

Pontificia Universidad Catolica de Chile

Santiago, Chile

2013 - 2013
Postdoctor Full Time

University of Ottawa

Ottawa, Canada

2010 - 2010
Postdoctor Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2010 - 2013

David Gonzalez, PhD Molecular and Celullar Biology student training. Pontificia Universidad Católica de Chile, 2012.
Osvaldo Contreras, undergraduate training, Pontificia Universidad Católica de Chile, 2012.
Nicolas Barrera, Tesis de grado, Tecnología Médica, Facultad Ciencias de la Salud, Universidad San Sebastian, 2014.
Alejandro Aedo, Tesis de grado, Tecnología Médica, Facultad Ciencias de la Salud, Universidad San Sebastian, 2015.
Jacob Mora, Tesis de grado, Bioquímica, Facultad Ciencias , Universidad San Sebastian, 2016.
Leila Fernandez, Tesis de grado, Tecnología Médica, Facultad Ciencias de la Salud, Universidad San Sebastian, 2017.
Jorge Maldonado, Tesis de grado, Tecnología Médica, Facultad Ciencias de la Salud, Universidad San Sebastian, 2017.
Felipe Gallardo, Tesis de grado, Tecnología Médica, Facultad Ciencias de la Salud, Universidad San Sebastian, 2018.
Cecilia Cornejo, Tesis de grado, Tecnología Médica, Facultad Ciencias de la Salud, Universidad San Sebastian, 2018.
Denisse Moreno, Tesis de grado, Tecnología Médica, Facultad Ciencias de la Salud, Universidad San Sebastian, 2019.
Karla Vega, Tesis de grado, Tecnología Médica, Facultad Ciencias de la Salud, Universidad San Sebastian, 2019.
Ricardo Pincheira, Tesis de grado, Tecnología Médica, Facultad Ciencias de la Salud, Universidad San Sebastian, 2019.
Yerko Espinoza, Tesis de grado, Tecnología Médica, Facultad Ciencias de la Salud, Universidad San Sebastian, 2019.
Daniela Puelles, Tesis de grado, Tecnología Médica, Facultad Ciencias de la Salud, Universidad San Sebastian, 2019.
Ayleen Mella, Tesis de grado, Tecnología Médica, Facultad Ciencias de la Salud, Universidad San Sebastian, 2019.

Organizador Primer Simposio en Salud de la Mujer - USS: Síndromes y Patologías del Embarazo, 2016, Universidad San Sebastián, Santiago, Chile.
Co-Organizador III Meeting on Research and Innovation in Vascular Health; V Meeting on Hypertension in Pregnancy, 2019, Bío-Bío, Chile

Award presentation

UNIVERSIDAD DE LOS ANDES

Chile, 2012

Best Poster Presentation at the, "1 Congreso de Terapia Celular"
Grant for assitence: Gordon Research Conferences

Gordon Research

Estados Unidos, 2006

Grant for assitance
Mejor Alumno Generación

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile, 2005

Premio por ser el mejor alumno de generación 1999, Bioquimica. Obtenida en la ceremonia de titulación.


Reduced RECK levels accelerate skeletal muscle differentiation, improve muscle regeneration, and decrease fibrosis Gutiérrez, Jaime. Gonzalez, David. Escalona-Rivano, Rodrigo. Takahashi, Chiaki. Brandan, Enrique. Article FASEB JOURNAL (2021)
Cholesterol uptake and efflux are impaired in human trophoblast cells from pregnancies with maternal supraphysiological hypercholesterolemia Fuenzalida B.; Cantin C.; Kallol S.; Carvajal L.; PastÃ©n V.; Contreras-Duarte S.; Albrecht C.; Gutierrez J.; Leiva A. Article ISI SCOPUS SCIENTIFIC REPORTS (2020)
Role of proteases in dysfunctional placental vascular remodelling in preeclampsia Gutiérrez, Jaime A.; Gómez, Isabel; Chiarello, Delia I; Salsoso, Rocío; Klein, Andres; Guzmán-Gutiérrez, Enrique; Toledo, Fernando; Sobrevia, Luis Article https://doi.org/10.1016/j.bbadis.2019.04.004 Biochimica et Biophysica Acta - Molecular Basis of Disease (2019)
Maternal supraphysiological hypercholesterolemia associates with endothelial dysfunction of the placental microvasculature Fuenzalida, B; Sobrevia, B; Cantin, C; Carvajal, L; Salsoso, R; Gutierrez, J; Contreras-Duarte, S; Sobrevia, L; Leiva, A Article ISI SCOPUS SCIENTIFIC REPORTS (2018)
Mechanisms of the effect of magnesium salts in preeclampsia Chiarello, DI; Marin, R; Proverbio, F; Coronado P.; Toledo, F; Salsoso, R; Gutierrez, J; Sobrevia, L Article ISI SCOPUS PLACENTA (2018)
Adenosine and preeclampsia Salsoso, R. .; Farias, M.; Gutierrez, J.; Pardo, F.; Chiarello, D. I.; Toledo, F.; Leiva, A.; Mate, A.; Vazquez, C. M.; Sobrevia, L Article ISI SCOPUS MOLECULAR ASPECTS OF MEDICINE (2017)
Adenosine and preeclampsia. Salsoso, Rocio; Farías, Marcelo; Gutiérrez, Jaime; Pardo, Fabian; Chiarello, Delia; Toledo, Fernando; Leiva, Andrea; Mate, Alfonzo; Vázquez Carmen; Sobrevia, Luis. Article MOLECULAR ASPECTS OF MEDICINE (2017)
Adenosine receptors: Modulators of lipid availability that are controlled by lipid levels Leiva, A.; Guzman-Gutierrez, E.; Contreras-Duarte, S.; Fuenzalida, B.; Cantin, C.; Carvajal, L.; Salsoso, R.; Gutierrez, J.; Pardo, F.; Sobrevia, L. Article ISI SCOPUS MOLECULAR ASPECTS OF MEDICINE (2017)
Adenosine receptors: Modulators of lipid availability that are controlled by lipid levels. Leiva, Andrea; Guzmán-Gutiérrez, Enrique; Contreras-Duarte, Susana; Fuenzalida, Barbara; Cantín, Claudette; Carvajal, Lorena; Salsoso, Rocio; Gutiérrez, Jaime; Pardo, Fabían; Sobrevia, Luis. Article MOLECULAR ASPECTS OF MEDICINE (2017)
Cross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes Jayabalan, Nanthini; Nair, Soumyalekshmi; Nuzhat, Zarin; Rice, Gregory E.; Zuñiga, Felipe A.; Sobrevia, Luis; Leiva, Andrea; Sanhueza, Carlos; Gutiérrez, Jaime Agustín; Lappas, Martha; Freeman, Dilys Jane; Salomon, Carlos Article ISI SCOPUS FRONTIERS IN ENDOCRINOLOGY (2017)
Molecular implications of adenosine in obesity Pardo, F.; Villalobos-Labra, R.; Chiarello, D. I.; Salsoso, R.; Toledo, F.; Gutierrez, J.; Leiva, A.; Sobrevia, L. Article ISI SCOPUS MOLECULAR ASPECTS OF MEDICINE (2017)
Molecular implications of adenosine in obesity. Pardo, Fabian; Villalobos-Labra, Roberto; Chiarello, Delia; Salsoso, Rocio; Toledo, Fernando; Gutierrez, Jaime; Leiva, Andrea, Sobrevia, Luis. Article MOLECULAR ASPECTS OF MEDICINE (2017)
Preeclampsia associates with RECK-dependent decrease in human trophoblasts migration and invasion Gutiérrez, Jaime; Aedo, Alejandro; Mora, Jacob; Maldonado, Jorge; Salsoso, Rocío; Toledo, Fernando; Farías, Marcelo; Pardo, Fabián; Leiva, Andrea; Sobrevia, Luis Article ISI SCOPUS PLACENTA (2017)
Sodium/proton exchanger isoform 1 regulates intracellular pH and cell proliferation in human ovarian cancer Sanhueza, C.; Araos, J.; Naranjo, L.; Toledo, F.; Beltran, A. R.; Ramirez, M. A.; Gutierrez, J.; Pardo, F.; Leiva, A.; Sobrevia, L Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
Sodium/proton exchanger isoform 1 regulates intracellular pH and cell proliferation in human ovarian cancer. Sanhueza, Carlos; Araos, Joaquin; Naranjo, Luis; Toledo, Fernando; Beltrán A; Ramírez Marcelo; Gutiérrez, Jaime; Pardo, Fabian; Leiva, Andrea; Sobrevia, Luis. Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
A Hypothesis for the Role of RECK in Angiogenesis Gutié rrez, Jaime; Droppelmann, Cristian; Salsoso, Rocío; Westermeier, Francisco; Toledo, Fernando; Salomon, Carlos; Sanhueza, Carlos; Pardo, Fabiá n; Leiva, Andrea; Luis Sobrevia Article Current Vascular Pharmacology (2016)
Are NHE1 and inducible nitric oxide synthase involved in human ovarian cancer? Sanhueza, Carlos; Araos, Joaquín; Naranjo, Luciano; Barros, Eric; Toledo, Lilian; Subiabre, Mario; Toledo, Fernando; Gutiérrez, Jaime; Chiarello, Indira; Pardo, Fabián; Leiva, Andrea; Sobrevia, Luis Article PHARMACOLOGICAL RESEARCH (2016)
Are NHE1 and inducible nitric oxide synthase involved in human ovarian cancer? Sanhueza, Carlos; Araos, Joaqun; Naranjo, Luciano; Barros, Eric; Toledo, Lilian; Subiabre, Mario; Toledo, Fernando; Gutirrez, Jaime; Chiarello, Delia I; Pardo, Fabin; Leiva, Andrea; Sobrevia, Luis Article ISI SCOPUS PHARMACOLOGICAL RESEARCH (2016)
Insulin Is a Key Modulator of Fetoplacental Endothelium Metabolic Disturbances in Gestational Diabetes Mellitus Sobrevia, Luis; Salsoso, Roco; Fuenzalida, Brbara; Barros, Eric; Toledo, Lilian; Silva, Luis; Pizarro, Carolina; Subiabre, Mario; Villalobos, Roberto; Araos, Joaqun; Toledo, Fernando; Gonzlez, Marcelo; Gutirrez, Jaime; Faras, Marcelo; Chiarello, Delia I; Pardo, Fabin; Leiva, Andrea Article ISI SCOPUS FRONTIERS IN PHYSIOLOGY (2016)
Insulin Is a Key Modulator of Fetoplacental Endothelium Metabolic Disturbances in Gestational Diabetes Mellitus Sobrevia, Luis; Salsoso, Rocí o; Fuenzalida, Bá rbara; Barros, Eric; Toledo, Lilian; Silva, Luis; Pizarro, Carolina; Subiabre, Mario; Villalobos, Roberto; Araos, Joaquí n; Toledo, Fernando; Gonzá lez, Marcelo; Gutié rrez, Jaime; Farí as, Marcelo; Chiarello, Delia I.; Pardo, Fabiá Leiva, Andrea Article Frontiers in Physiology (2016)
Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus Westermeier, F; Sez, T.; Arroyo, P; Toledo, F.; Gutirrez, J.; Sanhueza C.; Pardo F.; Leiva A.; Sobrevia L. Article ISI SCOPUS DIABETES-METABOLISM RESEARCH AND REVIEWS (2016)
Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus Westermeier, Francisco; Sá ez, Tamara; Arroyo, Pablo; Toledo, Fernando; Gutié rrez, Jaime; Sanhueza, Carlos; Pardo, Fabian; Leiva, Andrea; Sobrevia, Luis Article DIABETES-METABOLISM RESEARCH AND REVIEWS (2016)
Intracellular and extracellular pH dynamics in the human placenta from diabetes mellitus Araos, Joaquín; Silva, Luis; Salsoso, Rocío; Saez, Tamara; Barros, Eric; Toledo, Fernando; Gutiérrez, Jaime; Pardo, Fabián; Leiva, Andrea; Sanhueza, Carlos; Sobrevia, Luis Article PLACENTA (2016)
Modulation of Intracellular pH in Human Ovarian Cancer Sanhueza, Carlos; Araos, Joaquin; Naranjo, Luis; Villalobos, Roberto; Westermeier, Francisco; Salomon, Carlos; Beltrá n, A.R; Ramí rez, M. A; Gutié rrez, Jaime; Pardo, Fabián; Leiva, Andrea; Sobrevia, Luis Article CURRENT MOLECULAR MEDICINE (2016)
Modulation of Intracellular pH in Human Ovarian Cancer Sanhueza, C.; Araos, J.; Naranjo, L.; Villalobos, R.; Westermeier, F.; Salomon, C.; Beltran, A. R.; Ramirez, M. A.; Gutierrez, J.; Pardo, F.; Leiva, A.; Sobrevia, L. Article ISI CURRENT MOLECULAR MEDICINE (2016)
Nitric oxide and pH modulation in gynaecological cancer Sanhueza, C.; Araos, J.; Naranjo, L.; Barros, E.; Subiabre, M.; Toledo, F.; Gutierrez, J.; Chiarello, D. I.; Pardo, F.; Leiva, A.; Sobrevia, L. Article ISI SCOPUS JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2016)
Nitric oxide and pH modulation in gynaecological cancer. Sanhueza, Carlos; Araos, Joaquin; Naranjo, Luis; Barros, Eric; Subiabre, Mario; Toledo, Fernando; Gutiérrez, Jaime; Chiarello, Delia; Pardo, Fabian; Leiva, Andrea; Sobrevia, Luis. Article Journal of Cellular and Molecular Medicine (2016)
Nitric Oxide is a Central Common Metabolite in Vascular Dysfunction Associated with Diseases of Human Pregnancy Leiva, A.; Fuenzalida, B.; Barros, E.; Salsoso, R.; Saez, T.; Villalobos, R.; Silva, L.; Chiarello, I.; Toledo, F.; Gutierrez, J.; Sanhueza, C.; Pardo, F.; Sobrevia, L. Article ISI CURRENT VASCULAR PHARMACOLOGY (2016)
Nitric Oxide is a Central Common Metabolite in Vascular Dysfunction Associated with Diseases of Human Pregnancy Leiva, Andrea; Fuenzalida, Bá rbara; Barros, Eric; Sobrevia, Bastiá n; Salsoso, Rocí o; Sá ez, Tamara; Villalobos, Roberto; Silva, Luis; Chiarello, Indira; Toledo, Fernando; Gutié rrez, Jaime; Sanhueza, Carlos; Pardo, Fabiá Sobrevia, Luis Article Current Vascular Pharmacology (2016)
Role for Tetrahydrobiopterin in the Fetoplacental Endothelial Dysfunction in Maternal Supraphysiological Hypercholesterolemia Leiva, Andrea; Fuenzalida, Brbara; Westermeier, Francisco; Toledo, Fernando; Salomn, Carlos; Gutirrez, Jaime; Sanhueza, Carlos; Pardo, Fabin; Sobrevia, Luis Article ISI SCOPUS OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
Tetrahydrobiopterin Role in human umbilical vein endothelial dysfunction in maternal supraphysiological hypercholesterolemia Leiva, Andrea; Fuenzalida, Brbara; Salsoso, Roco; Barros, Eric; Toledo, Fernando; Gutirrez, Jaime; Pardo, Fabin; Sobrevia, Luis Article ISI SCOPUS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)
Tetrahydrobiopterin Role in Human Umbilical Vein Endothelial Dysfunction in Maternal Supraphysiological Hypercholesterolemia Leiva, Andrea; Fuenzalida, Bárbara; Salsoso, Rocío; Barros, Eric; Toledo, Fernando; Gutiérrez, Jaime; Pardo, Fabián; Sobrevia, Luis Article BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)
A Hypothesis for the Role of RECK in Angiogenesis Gutierrez, J.; Droppelmann, C. A.; Salsoso, R.; Westermeier, F.; Toledo, F.; Salomon, C.; Sanhueza, C.; Pardo, F.; Leiva, A.; Sobrevia, L. Article ISI, https://www.ncbi.nlm.nih.gov/pubmed/26463982 Current Vascular Pharmacology (2015)
Human supraphysiological gestational weight gain and fetoplacental vascular dysfunction Leiva, A.; Fuenzalida, B.; Pardo, F.; Westermeier, F.; Silva, L.; Saez, T.; Salsoso, R.; Gutierrez, J.; Sanhueza, C.; Sobrevia, L Article ISI, https://www.ncbi.nlm.nih.gov/pubmed/25869606 International Journal of Obesity (2015)
Human supraphysiological gestational weight gain and fetoplacental vascular dysfunction Pardo F.; Silva L.; Sáez T.; Salsoso R.; Gutiérrez J.; Sanhueza C.; Leiva A.; Sobrevia L. Article International Journal of Obesity (2015)
Intracellular and extracellular pH dynamics in the human placenta from diabetes mellitus Araos, J.; Silva, L.; Salsoso, R.; Saez, T.; Barros, E.; Toledo, F.; Gutierrez, J.; Pardo, F.; Leiva, A.; Sanhueza, C.; Sobrevia, L. Article ISI, https://www.ncbi.nlm.nih.gov/pubmed/27324099 Placenta (2015)
Mesenchymal stem cell therapy for doxorubicin cardiomyopathy: hopes and fears Ezquer, F.; Gutierrez, J.; Pardo, F.; Ezquer, M.; Caglevic, C.; Salgado, H. C.; Calligaris, S. D. Article ISI, https://www.ncbi.nlm.nih.gov/pubmed/26104315 ECANCERMEDICALSCIENCE (2015)
Mesenchymal stem cell therapy fordoxorubicin cardiomyopathy: hopes andfears Ezquer, Fernando; Gutié rrez, Jaime; Ezquer, Marcelo; Caglevic, Christian; Salgado, Helio C; Calligaris, Sebastiá n D. Article Stem Cell Research & Therapy (2015)
RECK-Mediated beta 1-Integrin Regulation by TGF-beta 1 Is Critical for Wound Contraction in Mice Gutirrez, Jaime; Droppelmann, Cristian A.; Contreras, Osvaldo; Takahashi, Chiaki; Brandan, Enrique; Cukierman, Edna Article ISI SCOPUS PLOS ONE (2015)
RECK-Mediated beta1-Integrin Regulation by TGF-beta1 Is Critical for Wound Contraction in Mice Gutierrez, Jaime; Droppelmann, Cristian; Contreras, Osvaldo; Takahashi, Chiaki; Brandan, Enrique Article PLoS One (2015)
RECK-Mediated beta1-Integrin Regulation by TGF-beta1 Is Critical for Wound Contraction in Mice Gutierrez, J.; Droppelmann, C. A.; Contreras, O.; Riquelme, C. A.; Takahashi, C.; Brandan, E. Article ISI, https://www.ncbi.nlm.nih.gov/pubmed/26247610 PLOS ONE (2015)
Role for Tetrahydrobiopterin in the Fetoplacental Endothelial Dysfunction in Maternal Supraphysiological Hypercholesterolemia Leiva, Andrea; Fuenzalida, Bárbara ; Westermeier, Francisco; Toledo, Fernando; Salomon, Carlos; Gutiérrez, Jaime; Sanhueza, Carlos; Pardo, Fabián; Sobrevia, Luis. Article Oxidative Medicine and Cellular Longevity (2015)
Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis Cabrera, Daniel; Gutiérrez, Jaime; Cabello-Verrugio, Claudio; Morales, Maria; Mezzano, Sergio; Fadic, Ricardo; Casar, Juan; Hancke, Juan L; Brandan, Enrique Article Skeletal Muscle (2014)
Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis Cabrera, D.; Gutierrez, J.; Cabello-Verrugio, C.; Morales, M. G.; Mezzano, S.; Fadic, R.; Casar, J. C.; Hancke, J. L.; Brandan, E. Article ISI, https://www.ncbi.nlm.nih.gov/pubmed/24655808 Skelet Muscle (2014)
Glypican-1 regulates myoblast response to HGF via Met in a lipid raft-dependent mechanism: effect on migration of skeletal muscle precursor cells Gutierrez, J.; Cabrera, D.; Brandan, E. Article ISI, https://www.ncbi.nlm.nih.gov/pubmed/24517345 Skelet Muscle (2014)
Glypican-1 regulates myoblast response to HGF via Met in a lipid raft-dependent mechanism: effect on migration of skeletal muscle precursor cells. Gutiérrez, Jaime; Cabrera, Daniel; Brandan, Enrique Article Skeletal Muscle (2014)
Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy Pessina, P.; Cabrera, D.; Morales, M. G.; Riquelme, C. A.; Gutierrez, J.; Serrano, A. L.; Brandan, E.; Munoz-Canoves, P. Article ISI, https://www.ncbi.nlm.nih.gov/pubmed/25157321 Skelet Muscle (2014)
Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy. Pessina P.; Cabrera D.; Morales MG. ; Gutié rrez J.; Serrano A.L. Article Skeletal Muscle (2014)
Human platelet activation/secretion and a membrane-associated urokinase-like activity induce the activation of the latent form of platelet transforming growth factor-beta 1 (TGF-beta 1) Panes, O; Gutierrez, J; Iruretagoyena, M; Brandan, E; Mezzano, D Article JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2013)
Mice Long-Term High-Fat Diet Feeding Recapitulates Human Cardiovascular Alterations: An Animal Model to Study the Early Phases of Diabetic Cardiomyopathy Calligaris, SD; Lecanda M; Solis, F; Ezquer, M; Gutierrez J.; Brandan, E.; Leiva A.; Sobrevia L.; Conget P. Article ISI SCOPUS PLOS ONE (2013)
Mice Long-Term High-Fat Diet Feeding Recapitulates Human Cardiovascular Alterations: An Animal Model to Study the Early Phases of Diabetic Cardiomyopathy Calligaris SD; Lecanda M; Solis F; Ezquer M.; Gutiérrez J.; Brandan E.; Leiva A.; Sobrevia L.; Conget P. Article PLOS ONE (2013)
Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy Morales, MG; Gutierrez, J; Cabello-Verrugio, C; Cabrera, D; Lipson, KE; Goldschmeding, R; Brandan, E Article HUMAN MOLECULAR GENETICS (2013)
Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy Morales, MG; Gutierrez J.; Cabello-Verrugio, C; cabrera, D; Lipson, KE; Goldschmeding, R; Brandan, E. Article ISI SCOPUS Human Molecular Genetics (2013)
Role of proteoglycans in the regulation of the skeletal muscle fibrotic response Brandan, E; Gutierrez, J Article FEBS JOURNAL (2013)
Role of skeletal muscle proteoglycans during myogenesis Brandan, E; Gutierrez, J Article MATRIX BIOLOGY (2013)
Decorin Interacts with Connective Tissue Growth Factor (CTGF)/CCN2 by LRR12 Inhibiting Its Biological Activity Vial, C; Gutierrez, J; Santander, C; Cabrera, D; Brandan, E Article JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Decorin Interacts with Connective Tissue Growth Factor (CTGF)/CCN2 by LRR12 Inhibiting Its Biological Activity Vial, C; Gutierrez J.; Santander C.; cabrera, D; Brandan, E. Article ISI SCOPUS Journal of Biological Chemistry (2011)
A Novel Mechanism of Sequestering Fibroblast Growth Factor 2 by Glypican in Lipid Rafts, Allowing Skeletal Muscle Differentiation Gutierrez, J; Brandan, E Article MOLECULAR AND CELLULAR BIOLOGY (2010)
A Novel Mechanism of Sequestering Fibroblast Growth Factor 2 by Glypican in Lipid Rafts, Allowing Skeletal Muscle Differentiation Gutierrez J.; Brandan, E. Article ISI SCOPUS Molecular and Cellular Biology (2010)
Matrix metalloproteinase-2-deficient fibroblasts exhibit an alteration in the fibrotic response to connective tissue growth factor/CCN2 because of an increase in the levels of endogenous fibronectin Droppelmann, C. A.; Gutierrez, J.; Vial, C.; Brandan, E. Article ISI, https://www.ncbi.nlm.nih.gov/pubmed/19276073 J Biol Chem (2009)
Matrix Metalloproteinase-2-deficient Fibroblasts Exhibit an Alteration in the Fibrotic Response to Connective Tissue Growth Factor/CCN2 because of an Increase in the Levels of Endogenous Fibronectin Droppelmann, CA; Gutierrez, J; Vial, C; Brandan, E Article JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Changes in secreted and cell associated proteoglycan synthesis during conversion of myoblasts to osteoblasts in response to bone morphogenetic protein-2: role of decorin in cell response to BMP-2 Gutierrez, J.; Osses, N.; Brandan, E. Article ISI, https://www.ncbi.nlm.nih.gov/pubmed/15920756 J Cell Physiol (2006)
Changes in secreted and cell associated proteoglycan synthesis during conversion of myoblasts to osteoblasts in response to bone morphogenetic protein-2: Role of decorin in cell response to BMP-2 Gutierrez, J; Osses, N; Brandan, E Article JOURNAL OF CELLULAR PHYSIOLOGY (2006)
Sulfation is required for bone morphogenetic protein 2-dependent Id1 induction Osses, N; Gutierrez, J; Lopez-Rovira, T; Ventura, F; Brandan, E Article BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Sulfation is required for bone morphogenetic protein 2-dependent Id1 induction Osses, N.; Gutierrez, J.; Lopez-Rovira, T.; Ventura, F.; Brandan, E. Article ISI, https://www.ncbi.nlm.nih.gov/pubmed/16647687 Biochem Biophys Res Commun (2006)


EFFECT OF MGSO(4) ON PROTEIN EXPRESSION AND EXOSOMES RELEASE FROM HUMAN PLACENTAL MICROVASCULAR ENDOTHELIAL CELLS FROM LATE-ONSET PREECLAMPSIA Chiarello, DI; Pardo, F; Salsoso, R; Fuenzalida, B; Gutierrez, J; Leiva, A; Sobrevia, L Abstract ISI PLACENTA (2017)


Role of RECK in preeclampsia development=> as a key regulator of cytotrophoblast invasiveness and spiral arteries remodeling. FONDECYT (1180935) Proyecto 2018-2022 Inv. Principal
Role of insulin receptors and adenosine receptors in prevention if fetoplacental endothelial dysfunction by insulin in women with gestational diabetes mellitus FONDECYT (1150377) Proyecto 2015-2018 Coinvestigador(a)
REDUCED RECK LEVELS IMPROVE THE MUSCLE CELL THERAPY AND DIMINISH THE FIBROSIS ASSOCIATED TO THE DYSTROPHIC MUSCLE FONDECYT (11110010) Proyecto 2011-2014 Inv. Responsable
Mejoramiento de la formación académica y científica en biología y fisiología celular=> Función de células madres en regeneración tisular 79090027 FONDECYT (79090027) Proyecto 2010-2013 Inv. Responsable


Role of extracellular vesicles in glioma progression Quezada, C; Torres, A; Niechi, I; Uribe, D; Contreras-Duarte, S; Toledo, F; San Martin, R; Gutierrez, J; Sobrevia, L Review ISI SCOPUS MOLECULAR ASPECTS OF MEDICINE (2018)
Role of proteoglycans in the regulation of the skeletal muscle fibrotic response Brandan, E.; Gutierrez J. Review ISI SCOPUS FEBS Journal (2013)
Role of skeletal muscle proteoglycans during myogenesis Brandan, E.; Gutierrez J. Review ISI SCOPUS Matrix Biology (2013)

Jaime Gutierrez

Associate Professor and Researcher

Tecnología Médica

Universidad San Sebastián

Santiago, Chile

LUIS SOBREVIA

Professor

Division of Obstetrics and Gynaecology

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Andrea Leiva

Profesor Asociado

Facultad de Ciencias de la Salud

Universidad San Sebastián

Santiago, Chile

Enrique Brandan

Profesor Titular

Biología Celular y Molecular

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Delia Chiarello

Investigador

Facultad de Ciencias de la Salud

Universidad San Sebastián

Santiago, Chile

Roberto Villalobos

Académico

Facultad de Medicina

Universidad de Valparaíso

San Felipe, Chile

Fabian Pardo

Profesor titular

Escuela de Medicina

Universidad de Valparaiso

San Felipe, Chile

Mario Subiabre

Marcelo Farias

Assistant Professor

Division of Obstetrics and Gynecology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE OBSTETRICIA

Santiago, Chile

Daniel Cabrera

Investigador Adjunto

Gastroenterología

Pontificia Universidad Catolica de Chile

santiago, Chile

Claudette Cantin

Profesor Asistente

Universidad San Sebastián

Puerto Montt, Chile

Susana Contreras

Assistant Professor

Nutrition and Dietetics

Universidad San Sebastián

Santiago, Chile

Bastian Sobrevia

Médico en etapa de Destinación y Formación

Servicio de Salud del Reloncaví

Puerto Montt, Chile

Enrique Guzman

Profesor Asistente

Bioquímica Clínica e Inmunología

Universidad de Concepción

Concepción, Chile

Tamara Sáez

Postdoctoral fellow

Obstetrics and Gynecology

University of Alberta

Edmonton, Canada

Felipe Zuñiga

Profesor Asistente

Bioquimica Clinica e Inmunologia

UNIVERSIDAD DE CONCEPCION

Concepcion, Chile

Daniel Uribe

Profesor Adhonorem

Institute of Biochemistry and Microbiology

Universidad Austral de Chile

Valdivia, Chile

MARCO RAMIREZ

Associate Professor

Universidad de Antofagasta

Antofagasta, Chile

Osvaldo Contreras

Sebastián Calligaris

Cordinador de Estudios Clínicos

Clínica Alemana

Santiago, Chile

Ana Beltrán

Profesor asociado

Educación

Universidad de Antofagasta

Antofagasta, Chile

Claudio Cabello

Full Professor

Ciencias Biologicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Maria Vial

Associate Professor/Profesor Asociado

Instituto de Ciencias e Innovación de Medicina

UNIVERSIDAD DEL DESARROLLO

Santiago, Chile

Lorena Carvajal

Ángelo Torres

Postdoctorado/Profesor Adjunto

Microbiología y Bioquímica

Universidad Austral de Chile

Valdivia, Chile

Claudia Quezada

Full Professor

Institute of Biochemistry and Microbiology

Universidad Austral de Chile

Valdivia, Chile

Jaime Agustin Gutierrez Perez

Líneas de Investigación

Educación

Molecular and Cellular Biology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2009

Molecular and Cellular Biology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007

Biochemist, Pontificia Universidad Católica de Chile. Chile, 2005

Experiencia Académica

Associate Researcher Full Time

Academic - Main Researcher Full Time

Experiencia Profesional

Researcher Other

Postdoctor Proyecto Anillos ACT-73 Full Time

Postdoctor Full Time

Postdoctor Full Time

Formación de Capital Humano

Difusión y Transferencia

Premios y Distinciones

Award presentation

Grant for assitence: Gordon Research Conferences

Mejor Alumno Generación

Article (65)

Abstract (1)

Proyecto (4)

Role of RECK in preeclampsia development=> as a key regulator of cytotrophoblast invasiveness and spiral arteries remodeling.

Role of insulin receptors and adenosine receptors in prevention if fetoplacental endothelial dysfunction by insulin in women with gestational diabetes mellitus

REDUCED RECK LEVELS IMPROVE THE MUSCLE CELL THERAPY AND DIMINISH THE FIBROSIS ASSOCIATED TO THE DYSTROPHIC MUSCLE

Mejoramiento de la formación académica y científica en biología y fisiología celular=> Función de células madres en regeneración tisular 79090027

Review (3)