Man

Lorena Paz Carvajal Rios

Líneas de Investigación


Autofagia y ox-LDL en el desarrollo placentario

Educación

  •  Ciencias Biológicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2023

Experiencia Académica

  •   Profesor instructor Other

    Universidad San Sebastián

    Medicina y Ciencia

    Santiago, Chile

    2021 - A la fecha

Experiencia Profesional

  •   Personal técnico de laboratorio Full Time

    Pontificia Universidad Católica de Chile

    Santiago, Chile

    2016 - 2017


 

Article (11)

Small extracellular vesicles from pregnant women with maternal supraphysiological hypercholesterolemia impair endothelial cell function in vitro
Autophagy Process in Trophoblast Cells Invasion and Differentiation: Similitude and Differences With Cancer Cells
Cholesterol uptake and efflux are impaired in human trophoblast cells from pregnancies with maternal supraphysiological hypercholesterolemia
Gestational Diabetes Mellitus Treatment Schemes Modify Maternal Plasma Cholesterol Levels Dependent to Women's Weight: Possible Impact on Feto-Placental Vascular Function
Eleveted maternal lipid level increases cholesterol efflux to hdl in human trophoblast but not in placental microvascular endothelial cells
Increased maternal lipid levels reduce the placental HDL and LDL cholesterol uptake in human trophoblast
Maternal supraphysiological dyslipidemia in pregnancy worse vascular response of umbilical vein rings from gestational diabetes mellitus.
Modulation of the placental HDL and LDL cholesterol uptake by the maternal lipids level in human trophoblast
Neonatal high-density lipoprotein from pregnancies with maternal supraphysiological hypercholesterolemia impairs nitric oxide synthase activity in human umbilical vein endothelial cells
Prevalence of maternal supraphysiological dyslipidemia in a group of Chilean pregnant women with gestational diabetes mellitus
Hypotensive and antihypertensive effects of a hydroalcoholic extract from Senecio nutans Sch. Bip. (Compositae) in mice=> Chronotropic and negative inotropic effect, a nifedipine-like action

Abstract (1)

PREECLAMPSIA IS ASSOCIATED WITH AN IMBALANCE IN THE PROTEIN EXPRESSION OF LDLR AND SR-BI, TOTAL CHOLESTEROL LEVELS AND AUTOPHAGY MARKERS IN THE HUMAN PLACENTA

Proyecto (1)

Involvement of PCSK9 in "human maternal supraphysiological hypercholesterolemia". Effects on placental cholesterol traffic and function of neonatal lipoproteins
4
Andrea Leiva

Profesor Asociado

Facultad de Ciencias de la Salud

Universidad San Sebastián

Santiago, Chile

3
Claudette Cantin

Profesor Asistente

Universidad San Sebastián

Puerto Montt, Chile

2
Susana Contreras

Assistant Professor

Nutrition and Dietetics

Universidad San Sebastián

Santiago, Chile

1
Jaime Gutierrez

Associate Professor and Researcher

Tecnología Médica

Universidad San Sebastián

Santiago, Chile

1
Marcelo Farias

Assistant Professor

Division of Obstetrics and Gynecology

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE, DEPARTAMENTO DE OBSTETRICIA

Santiago, Chile