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Claudia Paz Saavedra Sánchez

Full Professor

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

Structural and functional studies of Salmonella Typhimurium Porins; Structural and biochemical studies of enzymes; Molecular resistance strategies to adverse conditions present in extreme environments

Biochemistry, UNIVERSIDAD DE CHILE. Chile, 2002
Biochemist, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 1989
Masters in Biological Sciences with mention in Molecular and Cellular Biology, UNIVERSIDAD DE CHILE. Chile, 1997
Post-PhD Research, TEXAS A&M UNIVERSITY. Estados Unidos, 2003

Postdoctoral student Full Time

TEXAS A&M UNIVERSITY

Biology

College Station, Texas, Estados Unidos

2002 - 2003
Assistant professor Part Time

UNIVERSIDAD DE SANTIAGO DE CHILE

Faculty of chemistry and biology

Santiago, Chile

1995 - 2003
assistant professor Full Time

UNIVERSIDAD ANDRES BELLO

Faculty of Biological Sciences

Santiago, Chile

2005 - 2014
Full professor Full Time

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2015 - A la fecha

Assistant professor Full Time

Universidad de Talca

Talca, Chile

1989 - 1995
Associate professor Part Time

Universidad de Santiago

Santiago, Chile

1995 - 2004
Biochemistry School Director Full Time

Universidad Andrés Bello

Santiago, Chile

2005 - A la fecha
Academic microbiology area Part Time

Inacap

Santiago, Chile

1995 - 2004

Fernando Olate; U. Chile / UNAB-Biochemistry; Sponsor; 2009.
Andrea Lorenzi; U. Chile / UNAB-Biochemistry; Sponsor; 2009.
Patricia Muñoz; U. Chile / UNAB-Biochemistry; Sponsor; 2009.
Miriam Barros; U. Chile / UNAB-Biochemistry; Sponsor; 2009.
Nataly Contreras; U. Chile / UNAB-Biochemistry; Sponsor; 2009.
Carolina Leal; U. Chile / UNAB-Biochemistry; Sponsor; 2009.
Mauricio Valdivia; USACH / UNAB-Biochemistry; Sponsor; 2010.
Juan Pablo Monras; USACH / UNAB-Biochemistry; Sponsor; 2010.
Cristian Sabotier; USACH / UNAB-Biochemistry; Sponsor; 2010.

Catalina Chahuán; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2008-2009.
Debbie Monsalva; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2010.
Samuel Parra; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2009-2010.
Patricio Guerrero; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2010-2011.
Carolina Cabezas; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2012.
Paulina Calderón; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2012.
Ricardo Álvarez; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2012.
Roberto Luraschi; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2013.
Alan Briones; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2013-2014.
Ana Inostroza; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2013-2014.
Sylvana Urra; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2013-2014.
Cesar Salinas; UNAB / Biochemistry – Master in Biochemistry; Tutor of Undergraduate Research Unit; 2015-2016.

María Graciela Delgado; Master in Biochemistry/UNAB; Masters thesis tutor; 2009.
Juan Ignacio Gutiérrez; Master in Biochemistry/UNAB; Masters thesis tutor; 2009.
Nelson Caro; Master in Biochemistry/UNAB; Masters thesis tutor; 2009.
Bernardo Collao; Master in Biochemistry/UNAB; Masters thesis tutor; 2010.
Catalina Chahuán; Master in Biochemistry/UNAB; Masters thesis tutor; 2010.
Samuel Parra; Master in Biochemistry/UNAB; Masters thesis tutor; 2011.
Nicolás Pacheco; Master in Biochemistry/UNAB; Masters thesis tutor; 2012.
Debbie Monsalva; Master in Biochemistry/UNAB; Masters thesis tutor; 2012.
Marlen Espinoza; Master in Biochemistry/UNAB; Masters thesis tutor; 2013-2014.
Roberto Luraschi; Master in Biochemistry/UNAB; Masters thesis tutor; 2013-2014.
Carolina Cabezas; Master in Biochemistry/UNAB; Masters thesis tutor; 2014.
Alan Briones; Master in Biochemistry/UNAB; Masters thesis tutor; 2014.
Ana Inostroza; Master in Biochemistry/UNAB; Masters thesis tutor; 2014.
Sylvana Urra; Master in Biochemistry/UNAB; Masters thesis tutor; 2014.
Cesar Salinas; Master in Biochemistry/UNAB; Masters thesis tutor; 2016.
Camila Aguirre; Master in Biochemistry/UNAB; Masters thesis tutor; 2017.

Fernando Gil Michell; Molecular Biosciences PhD program/UNAB; Thesis tutor; 2010.
José Miguel Villarreal; Biotechnology PhD program/UNAB; Thesis tutor; 2010.
Francisco Ipinza; Biotechnology PhD program/UNAB; Thesis tutor; 2012.
Eduardo Morales; Molecular Biosciences PhD program/UNAB; Thesis tutor; 2013
Bernardo Collao; Molecular Biosciences PhD program/UNAB; Thesis tutor; 2014.

Mario Navarrete; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2010.
Matías Jofre; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2011.
Cristóbal Mujica; Biotechnology PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2011.
Annettte Nicole Trombert; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2011.
Hugo González; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2011.
Héctor Osorio; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2012.
Daniela Doñas; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2012.
Nicolás Villagra; Molecular Biosciences PhD program/UNAB; Member of the evaluation committee preliminary draft thesis ; 2012.

María Graciela Delgado; Master in Biochemistry/UNAB; President of examination committee degree; 2009.
Juan Ignacio Gutiérrez; Master in Biochemistry/UNAB; President of examination committee degree; 2009.
Simón Vidal; Master in Biochemistry/UNAB; Degree examination committee member; 2009.
Bernardo Collao; Master in Biochemistry/UNAB; President of examination committee degree; 2009.
Carlos Rosales; Master in Biochemistry/UNAB; Degree examination committee member; 2009.

Cristobal Mujica; Molecular Biosciences PhD program/UNAB; President qualifying examination committee; 2009.
Héctor Osorio; Molecular Biosciences PhD program/UNAB; Qualifying examination committee member; 2010.
Matias Jofré; Molecular Biosciences PhD program/UNAB; Qualifying examination committee member; 2010.
Annette Nicole Trombert; Molecular Biosciences PhD program/UNAB; Qualifying examination committee member; 2011.
Daniela Doñas; Molecular Biosciences PhD program/UNAB; Qualifying examination committee member; 2013.
César Echeverría; Molecular Biosciences PhD program/UNAB; Qualifying examination committee member; 2013.
Nicolás Villagra; Molecular Biosciences PhD program/UNAB; Qualifying examination committee member; 2014.

Bernardo Collao; Molecular Biosciences PhD program/UNAB; Research unit Tutor; 2010.
Eduardo Morales; Molecular Biosciences PhD program/UNAB; Research unit Tutor; 2010.

Actividades de Difusion

2020
Nombre Actividad realizada N° estudiantes DBCM participantes (1) N° académicos participantes (2) N° total de asistentes inlcyendo (1) y (2) Web page o link de la evidecia de la actividad (o adjuntar imagen en el email)
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Nota 0 1 1 https://www.biobiochile.cl/noticias/nacional/chile/2020/09/28/expertos-sugieren-que-baja-de-casos-activos-es-efecto-del-rezago-de-fiestas-patrias.shtml
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Entrevista 0 1 1 Claudia Saavedra, académica de la Unab
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Nota 0 1 1 https://www.biobiochile.cl/noticias/nacional/chile/2020/12/06/el-calor-y-la-transmision-aerea-de-la-covid-19-como-ventilar-los-espacios-cerrados-este-verano.shtml
Nota 0 1 1 https://www.biobiochile.cl/noticias/nacional/chile/2020/12/15/el-preocupante-grafico-que-exhibio-el-ministro-paris-para-comparar-a-chile-con-la-union-europea.shtml
Entrevista 0 1 1 Influyentes: Entrevista a Claudia Saavedra, pdta SOMICH y académica UNAB.


Mobile genetic elements drive the multidrug resistance and spread of Salmonella serotypes along a poultry meat production line Kruger, Gabriel I.; Pardo-Este, Coral; Zepeda, Phillippi; Olivares-Pacheco, Jorge; Galleguillos, Nicolas; Suarez, Marcia; Castro-Severyn, Juan; Alvarez-Thon, Luis; Tello, Mario; Valdes, Jorge H.; Saavedra, Claudia P. Article ISI FRONTIERS IN MICROBIOLOGY (2023)
Biochemical, genomic and structural characteristics of the Acr3 pump in Exiguobacterium strains isolated from arsenic-rich Salar de Huasco sediments Castro-Severyn, Juan; Pardo-Este, Coral; Araya-Duran, Ingrid; Gariazzo, Valentina; Cabezas, Carolina; Valdes, Jorge; Remonsellez, Francisco; Saavedra, Claudia P. Article ISI FRONTIERS IN MICROBIOLOGY (2022)
Genetic regulation of the ompX porin of Salmonella Typhimurium in response to hydrogen peroxide stress BRIONES, A. C.; Lorca, D.; Cofre, A.; Cabezas, C. E.; Krueger, G. I.; Pardo-Este, C.; Baquedano, M. S.; Salinas, C. R.; Espinoza, M.; Castro-Severyn, J.; Remonsellez, F.; Hidalgo, A. A.; Morales, E. H.; Saavedra, C. P. Article ISI SCIELO BIOLOGICAL RESEARCH (2022)
Activation of regulator ArcA in the presence of hypochlorite in Salmonella enterica serovar Typhimurium Cabezas, Carolina E.; Laulie, Arlette M.; Briones, Alan C.; Pardo-Este, Coral; Lorca, Diego E.; Cofre, Agustin A.; Morales, Eduardo H.; Mora, Aracely Y.; Kruger, Gabriel, I; Bueno, Susan M.; Hidalgo, Alejandr A.; Saavedra, Claudia P. Article ISI BIOCHIMIE (2021)
Genetic Characterization of Salmonella Infantis with Multiple Drug Resistance Profiles Isolated from a Poultry-Farm in Chile Pardo-Este, Coral; Lorca, Diego; Castro-Severyn, Juan; Krueger, Gabriel; Alvarez-Thon, Luis; Zepeda, Phillippi; Sulbaran-Bracho, Yoelvis; Hidalgo, Alejandro; Tello, Mario; Molina, Franck; Molina, Laurence; Remonsellez, Francisco; Castro-Nallar, Eduardo; Saavedra, Claudia Article ISI Microorganisms (2021)
Living to the High Extreme: Unraveling the Composition, Structure, and Functional Insights of Bacterial Communities Thriving in the Arsenic-Rich Salar de Huasco Altiplanic Ecosystem Castro-Severyn, Juan; Pardo-Este, Coral; Mendez, Katterinne N.; Fortt, Jonathan; Marquez, Sebastian; Molina, Franck; Castro-Nallar, Eduardo; Remonsellez, Francisco; Saavedra, Claudia P. Article ISI MICROBIOLOGY SPECTRUM (2021)
Living to the High Extreme: Unraveling the Composition, Structure, and Functional Insights of Bacterial Communities Thriving in the Arsenic-Rich Salar de Huasco Altiplanic Ecosystem. Castro-Severyn, Juan Article MICROBIOLOGY SPECTRUM (2021)
Genomic variation and arsenic tolerance emerged as niche specific adaptations by different Exiguobacterium strains isolated from the extreme Salar de Huasco environment in Chilean – Altiplano. Journal: Frontiers in Microbiology, section Evolutionary and Genomic Microbiology Juan Castro-Severyn, Coral Pardo-Esté, Katterinne Ninoska Mendez, Naiyulin Morales, Sebastián Luis Márquez Miranda, Franck Molina, Francisco Remonsellez, Eduardo Castro-Nallar, Claudia P Saavedra Article ISI/SCOPUS FRONTIERS IN MICROBIOLOGY (2020)
Inactivation of Glutamine Synthetase-Coding Gene glnA Increases Susceptibility to Quinolones Through Increasing Outer Membrane Protein F in Salmonella enterica Serovar Typhi Millanao A.R.; Mora A.Y.; Saavedra, C. P.; Villagra N.A.; Mora, G. C.; Hidalgo, A. A. Article ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2020)
Real-Time Estimation of R-t for Supporting Public-Health Policies Against COVID-19 Contreras, Sebastian; Villavicencio, H. Andres; Medina-Ortiz, David; Saavedra, Claudia P.; Olivera-Nappa, Alvaro Article ISI FRONTIERS IN PUBLIC HEALTH (2020)
Cysteine auxotrophy drives reduced susceptibility to quinolones and paraquat by inducing the expression of efflux-pump systems and detoxifying enzymes in S. Typhimurium Villagra NA, Valenzuela LM, Mora AY, Millanao AR, Saavedra CP, Mora GC, Hidalgo AA. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
The Transcription Factor ArcA Modulates Salmonella's Metabolism in Response to Neutrophil Hypochlorous Acid-Mediated Stress Pardo-Este, Coral; Castro-Severyn, Juan; Kruger, Gabriel, I; Cabezas, Carolina Elizabeth; BRIONES, ALAN CRISTOBAL; Aguirre, Camila; Morales, Naiyulin; Baquedano, Maria Soledad; Sulbaran, Yoelvis Noe; Hidalgo, Alejandro A.; Meneses, Claudio; Poblete-Castro, Ignacio; Castro-Nallar, Eduardo; Valvano, Miguel A.; Saavedra, Claudia P. Article ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2019)
Characterization and Salt Response in Recurrent Halotolerant Exiguobacterium sp SH31 Isolated From Sediments of Salar de Huasco, Chilean Altiplano Remonsellez, F; Castro-Severyn, J; Pardo-Este, C; Aguilar, P; Fortt, J; Salinas, C; Barahona, S; Leon, J; Fuentes, B.; Areche, C; Hernandez, KL; Aguayo, D; Saavedra, CP Article ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2018)
The ArcAB two-component regulatory system promotes resistance to reactive oxygen species and systemic infection by Salmonella Typhimurium Pardo-Este, C; Hidalgo, AA; Aguirre, C; BRIONES, AC; Cabezas, CE; Castro-Severyn, J; Fuentes, JA; Opazo, CM; Riedel, CA; Otero, C; Pacheco, R; Valvano, MA; Saavedra, CP Article ISI SCOPUS PLOS ONE (2018)
The transcription factor SlyA from Salmonella Typhimurium regulates genes in response to hydrogen peroxide and sodium hypochlorite Cabezas, Carolina E.; BRIONES, ALAN C.; Aguirre, Camila; Pardo-Este, Coral; Castro-Severyn, Juan; Salinas, Cesar R.; Baquedano, Maria S.; Hidalgo, Alejandro A.; Fuentes, Juan A; Morales, Eduardo H; Meneses, Claudio A.; Castro-Nallar, Eduardo; Paz Saavedra, Claudia Article ISI SCOPUS RESEARCH IN MICROBIOLOGY (2018)
Comparative Genomics Analysis of a New Exiguobacterium Strain from Salar de Huasco Reveals a Repertoire of Stress-Related Genes and Arsenic Resistance Juan Castro-Severyn, Francisco Remonsellez, Sandro L Valenzuela, Cesar Salinas, Jonathan Fortt, Pablo Aguilar, Coral Pardo-Esté, Cristina Dorador, Raquel Quatrini, Franck Molina, Daniel Aguayo, Eduardo Castro-Nallar, Claudia P Saavedra Article ISI SCOPUS FRONTIERS IN MICROBIOLOGY (2017)
Hydrogen peroxide and hypochlorous acid influx through the major S. Typhimurium porin OmpD is affected by substitution of key residues of the channel Aguayo, D; Pacheco N.; Morales E.H; Collao B; Luraschi, R.; Cabezas, C.; Calderon, P; Gonzalez-Nilo, F; Gil, F; Calderon I.L.; Saavedra, C. P. Article ISI SCOPUS ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2015)
Pseudogenization of sopA and sopE2 is functionally linked and contributes to virulence of Salmonella enterica serovar Typhi Valenzuela, LM; Hidalgo, AA; Rodríguez L.; urrutia im; Ortega, AP; villagra NA; Paredes Sabja D; Calderon, IL; Gil, F; Saavedra, CP; Mora, GC; Fuentes, JA. Article ISI SCOPUS INFECTION GENETICS AND EVOLUTION (2015)
Participation of the Salmonella OmpD Porin in the Infection of RAW264.7 Macrophages and BALB/c Mice IPINZA, F.; Collao B; Monsalva D.; Bustamante V.H.; Luraschi, R.; Alegria-Arcos M.; Almonacid D.E.; Aguayo, D; Calderon I.L.; Gil, F; Santiviago, C. A.; Morales E.H; Calva E.; Saavedra, C. P. Article ISI SCOPUS PLOS ONE (2014)
Participation of the Salmonella OmpD porin in the infection of RAW264.7 macrophages and BALB/c mice. Ipinza, Francisco; Collao, Bernardo; Monsalva, Debbie; Bustamante, Victor H; Luraschi, Roberto; Alegría-Arcos, Melissa; Almonacid, Daniel E; Aguayo, Daniel; Calderón, Iván L; Gil, Fernando; Santiviago, Carlos A; Morales, Eduardo H; Calva, Edmundo; Saavedra, Claudia P Article PloS one (2014)
Role of Salmonella Typhimurium small RNAs RyhB-1 and RyhB-2 in the oxidative stress response Calderon, IL; Morales, EH; Collao, B; Calderon, PF; Chahuan, CA; Acuna, LG; Gil, F; Saavedra, CP Article RESEARCH IN MICROBIOLOGY (2014)
The small RNA RyhB homologs from Salmonella typhimurium participate in the response to S-nitrosoglutathione-induced stress. Calderón, Paulina F; Morales, Eduardo H; Acuña, Lillian G; Fuentes, Danitza N; Gil, Fernando; Porwollik, S; McClelland, Michael; Saavedra, Claudia P; Calderón, Iván L Article Biochemical and biophysical research communications (2014)
ompW is cooperatively upregulated by MarA and SoxS in response to menadione Collao B; Morales, EH; Gil, F; Calderon, IL; Saavedra, CP Article ISI SCOPUS MICROBIOLOGY-SGM (2013)
ompW is cooperatively upregulated by MarA and SoxS in response to menadione Collao, B; Morales, EH; Gil, F; Calderon, IL; Saavedra, CP Article MICROBIOLOGY-SGM (2013)
Optimal entanglement concentration for photonic qutrits encoded in path variables Marques B.; Matoso, AA; Pimenta, WM; Gutierrez-Esparza, AJ; Lima G.; Neves L.; Delgado, A.; SAAVEDRA, C; Padua, S. Article ISI SCOPUS Physical Review A - Atomic, Molecular, and Optical Physics (2013)
Probing the ArcA regulon under aerobic/ROS conditions in Salmonella enterica serovar Typhimurium Morales, EH; Collao, B; Desai, PT; Calderon, IL; Gil, F; Luraschi R.; Porwollik, S; McClelland, M; Saavedra, CP Article BMC GENOMICS (2013)
Probing the ArcA regulon under aerobic/ROS conditions in Salmonella enterica serovar Typhimurium Morales, EH; Collao B; Desai, PT; Calderon, IL; Gil, F; Luraschi, R.; Porwollik, S; McClelland, M; Saavedra, CP Article ISI SCOPUS BMC GENOMICS (2013)
Salmonella enterica serovar Typhimurium BaeSR two-component system positively regulates sodA in response to ciprofloxacin Guerrero, P.; Collao B; Alvarez R.; Salinas,H.; Morales, EH; Calderon, IL; Saavedra, CP; Gil, F Article ISI SCOPUS MICROBIOLOGY-SGM (2013)
Salmonella enterica serovar Typhimurium BaeSR two-component system positively regulates sodA in response to ciprofloxacin Guerrero, P; Collao, B; Alvarez, R; Salinas H.; Morales, EH; Calderon, IL; Saavedra, CP; Gil, F Article MICROBIOLOGY-SGM (2013)
Characterization of the BaeSR two-component system from Salmonella Typhimurium and its role in ciprofloxacin-induced mdtA expression Guerrero, P.; Collao B; Morales E.H; Calderon I.L.; IPINZA, F.; Parra, S; Saavedra, C. P.; Gil, F Article ISI SCOPUS ARCHIVES OF MICROBIOLOGY (2012)
Differential expression of the transcription factors MarA, Rob, and SoxS of Salmonella Typhimurium in response to sodium hypochlorite: down-regulation of rob by MarA and SoxS Collao, B; Morales E.H.; Gil, F; Polanco R.; Calderon I.L.; Saavedra C.P. Article ARCHIVES OF MICROBIOLOGY (2012)
Differential expression of the transcription factors MarA, Rob, and SoxS of Salmonella Typhimurium in response to sodium hypochlorite: down-regulation of rob by MarA and SoxS Collao B; Morales E.H; Gil, F; Polanco, R.; Calderon I.L.; Saavedra, C. P. Article ISI SCOPUS ARCHIVES OF MICROBIOLOGY (2012)
Hypochlorous acid and hydrogen peroxide-induced negative regulation of Salmonella enterica serovar Typhimurium ompW by the response regulator ArcA Morales E.H.; Calderan I.L.; Collao, B; Gil, F; Porwollik, S; McClelland, M; Saavedra C.P. Article BMC MICROBIOLOGY (2012)
Hypochlorous acid and hydrogen peroxide-induced negative regulation of Salmonella enterica serovar Typhimurium ompW by the response regulator ArcA Morales E.H; Calderan I.L.; Collao B; Gil, F; Porwollik, S; McClelland, M; Saavedra, C. P. Article ISI SCOPUS BMC MICROBIOLOGY (2012)
cAMP receptor protein (CRP) positively regulates the yihU-yshA operon in Salmonella enterica serovar Typhi Villarreal, JM; Hernandez-Lucas, I; Gil, F; Calderon, IL; Calva E.; Saavedra, CP Article ISI SCOPUS MICROBIOLOGY (2011)
cAMP receptor protein (CRP) positively regulates the yihU-yshA operon in Salmonella enterica serovar Typhi Villarreal, JM; Hernandez-Lucas, I; Gil, F; Calderon, IL; Calva E.; Saavedra, CP Article MICROBIOLOGY-SGM (2011)
Quantum process reconstruction based on mutually unbiased basis Fernandez-Perez, A; Klimov, AB; SAAVEDRA, C Article ISI SCOPUS Physical Review A - Atomic, Molecular, and Optical Physics (2011)
Response regulator ArcA of Salmonella enterica serovar Typhimurium downregulates expression of OmpD, a porin facilitating uptake of hydrogen peroxide Calderon I.L.; Morales, E; Caro N.J.; Chahuan C.A.; Collao, B; Gil, F; Villarreal J.M.; Ipinza F.; Mora G.C.; Saavedra C.P. Article RESEARCH IN MICROBIOLOGY (2011)
Response regulator ArcA of Salmonella enterica serovar Typhimurium downregulates expression of OmpD, a porin facilitating uptake of hydrogen peroxide Calderon I.L.; Morales E. ; Caro N.J.; Chahuan C.A.; Collao B; Gil, F; Villarreal J.M.; IPINZA, F.; Mora, G. C.; Saavedra, C. P. Article ISI SCOPUS RESEARCH IN MICROBIOLOGY (2011)
Cloning, purification and characterization of Geobacillus stearothermophilus V uroporphyrinogen-III C-methyltransferase: evaluation of its role in resistance to potassium tellurite in Escherichia coli Araya, MA; Tantatean, JC; Perez, JM; Fuentes DE; Calderon, LL; Saavedra, CP; Burra, R; Chasteen, TG; Vásquez CC Article ISI SCOPUS RESEARCH IN MICROBIOLOGY (2009)
SoxS regulates the expression of the Salmonella enterica serovar Typhimurium ompW gene Gil, F; Hernandez-Lucas, I; Polanco R.; Pacheco N.; Collao, B; Villarreal, JM; Nardocci G.; Calva E.; Saavedra, CP Article MICROBIOLOGY-SGM (2009)
SoxS regulates the expression of the Salmonella enterica serovar Typhimurium ompW gene Gil, F; Hernandez-Lucas, I; Polanco, R.; Pacheco N.; Collao B; Villarreal, JM; Nardocci, G; Calva E.; Saavedra, CP Article ISI SCOPUS MICROBIOLOGY-SGM (2009)
SmvA, and not AcrB, is the major efflux pump for acriflavine and related compounds in Salmonella enterica serovar Typhimurium villagra NA; Hidalgo, AA; Santiviago, CA; Saavedra, CP; Mora, GC Article ISI SCOPUS JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2008)
SmvA, and not AcrB, is the major efflux pump for acriflavine and related compounds in Salmonella enterica serovar Typhimurium. Villagra, Nicolás A; Hidalgo, Alejandro A; Santiviago, Carlos A; Saavedra, Claudia P; Mora, Guido C Article The Journal of antimicrobial chemotherapy (2008)
The ompW (porin) gene mediates methyl viologen (paraquat) efflux in Salmonella enterica serovar Typhimurium Gil, F; Ipinza F.; Fuentes J.; Pumeron, P; Villarreal, JM; Aspee, A; Mora, GC; Vasquez, CC; Saavedra, C Article RESEARCH IN MICROBIOLOGY (2007)
The ompW (porin) gene mediates methyl viologen (paraquat) efflux in Salmonella enterica serovar Typhimurium Gil, F; IPINZA, F.; Fuentes, J; Pumeron, P; Villarreal, JM; Aspée A.; Mora, GC; Vásquez CC; SAAVEDRA, C Article ISI SCOPUS RESEARCH IN MICROBIOLOGY (2007)
Catalases Are NAD(P)H-Dependent Tellurite Reductases Calderon, IL; Arenas FA; Perez, JM; Fuentes DE; Araya, MA; Saavedra, CP; Tantalean, JC; Pichuantes, SE; Youderian, PA; Vásquez CC Article ISI SCOPUS PLOS ONE (2006)
Catalases are NAD(P)H-dependent tellurite reductases. Calderón, Iván L; Arenas, Felipe A; Pérez, José Manuel; Fuentes, Derie E; Araya, Manuel A; Saavedra, Claudia P; Tantaleán, Juan C; Pichuantes, Sergio E; Youderian, Philip A; Vásquez, Claudio C Article PloS one (2006)
Effective Hamiltonian approach to periodically perturbed quantum optical systems Sainz, I.; Klimov, AB; SAAVEDRA, C Article ISI SCOPUS Physics Letters A (2006)
Expression of the ubiE gene of Geobacillus stearothermophilus V in Escherichia coli K-12 mediates the evolution of selenium compounds into the headspace of selenite- and selenate-amended cultures Swearingen, JW; Fuentes DE; Araya, MA; Plishker, MF; Saavedra, CP; Chasteen, TG; Vásquez CC Article ISI SCOPUS APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2006)
Expression of the ubiE gene of Geobacillus stearothermophilus V in Escherichia coli K-12 mediates the evolution of selenium compounds into the headspace of selenite- and selenate-amended cultures. Swearingen, J W; Fuentes, D E; Araya, M A; Plishker, M F; Saavedra, C P; Chasteen, T G; Vásquez, C C Article Applied and environmental microbiology (2006)
Identification of biogenic dimethyl selenodisulfide in the headspace gases above genetically modified Escherichia coli Swearingen, JW; Frankel, DP; Fuentes DE; Saavedra, CP; Vasquez, CCV; Chasteen, TG Article ISI SCOPUS ANALYTICAL BIOCHEMISTRY (2006)
Identification of biogenic dimethyl selenodisulfide in the headspace gases above genetically modified Escherichia coli. Swearingen, Jerry W; Frankel, Danielle P; Fuentes, Derie E; Saavedra, Claudia P; Vásquez, Claudio C; Chasteen, Thomas G Article Analytical biochemistry (2006)
Novel mesogenic asymmetric diacylhydrazines: synthesis, mesomorphic behaviour and X-ray study Parra,M; Hidalgo, P.; Barberá J.; Carrasco, E; SAAVEDRA, C Article ISI SCOPUS LIQUID CRYSTALS (2006)
Propagation of spatially entangled qudits through free space Lima G.; Neves L.; Santos, IF; Gomez, JGA; SAAVEDRA, C; Padua, S. Article ISI SCOPUS PHYSICAL REVIEW A (2006)
Robustness analysis of the neural gas learning algorithm SAAVEDRA, C; Moreno, S.; Salas, R.; Allende, H. Article ISI BIO-INSPIRED SYSTEMS AND APPLICATIONS: FROM ROBOTICS TO AMBIENT INTELLIGENCE, PT II (2006)
Entanglement swapping via quantum state discrimination Delgado, A.; Roa L.; RETAMAL, JC; SAAVEDRA, C Article ISI SCOPUS PHYSICAL REVIEW A (2005)
Flexible Architecture of Self Organizing Maps for changing environments Salas, R.; Allende, H.; Moreno, SN; SAAVEDRA, C Article ISI BIO-INSPIRED SYSTEMS AND APPLICATIONS: FROM ROBOTICS TO AMBIENT INTELLIGENCE, PT II (2005)
Generation of entangled states of qudits using twin photons Neves L.; Lima G.; Gomez, JGA; Monken, CH; SAAVEDRA, C; Padua, S. Article ISI SCOPUS PHYSICAL REVIEW LETTERS (2005)
K-Dynamical Self Organizing Maps SAAVEDRA, C; Allende, H.; Moreno, S.; Salas, R. Article ISI BIO-INSPIRED SYSTEMS AND APPLICATIONS: FROM ROBOTICS TO AMBIENT INTELLIGENCE, PT II (2005)
The product of the qacC gene of Staphylococcus epidermidis CH mediates resistance to beta-lactam antibiotics in Gram-positive and Gram-negative bacteria Fuentes DE; Navarro, CA; Tantalean, JC; Araya, MA; Saavedra, CP; Perez, JM; Calderon, IL; Youderian, PA; Mora, GC; Vásquez CC Article ISI SCOPUS RESEARCH IN MICROBIOLOGY (2005)
The product of the qacC gene of Staphylococcus epidermidis CH mediates resistance to beta-lactam antibiotics in gram-positive and gram-negative bacteria. Fuentes, Derie E; Navarro, Claudio A; Tantaleán, Juan C; Araya, Manuel A; Saavedra, Claudia P; Pérez, José M; Calderón, Iván L; Youderian, Phil A; Mora, Guido C; Vásquez, Claudio C Article Research in microbiology (2005)
Biochemical characterization of a thermostable cysteine synthase from Geobacillus stearothermophilus V Saavedra, CP; Encinas, MV; Araya, MA; Perez, JM; Tantalean, JC; Fuentes DE; Calderon, IL; Pichuantes, SE; Vásquez CC Article ISI BIOCHIMIE (2004)
Biochemical characterization of a thermostable cysteine synthase from Geobacillus stearothermophilus V. Saavedra, C P; Encinas, M V; Araya, M A; Pérez, J M; Tantaleán, J C; Fuentes, D E; Calderón, I L; Pichuantes, S E; Vásquez, C C Article Biochimie (2004)
Controlled generation of maximally entangled qudits using twin photons Neves L.; Padua, S.; SAAVEDRA, C Article ISI SCOPUS PHYSICAL REVIEW A (2004)
Effective resonant interactions via a driving field Klimov, AB; Sainz, I.; SAAVEDRA, C Article ISI SCOPUS JOURNAL OF OPTICS B-QUANTUM AND SEMICLASSICAL OPTICS (2004)
Entanglement rate in qubits Guzman, R; RETAMAL, JC; Romero, JL; SAAVEDRA, C Article ISI SCOPUS Physics Letters A (2004)
Geobacillus stearothermophilus V ubiE gene product is involved in the evolution of dimethyl telluride in Escherichia coli K-12 cultures amended with potassium tellurate but not with potassium tellurite Araya, MA; Swearingen, JW; Plishker, MF; Saavedra, CP; Chasteen, TG; Vásquez CC Article ISI SCOPUS JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2004)
Geobacillus stearothermophilus V ubiE gene product is involved in the evolution of dimethyl telluride in Escherichia coli K-12 cultures amended with potassium tellurate but not with potassium tellurite. Araya, Manuel A; Swearingen, Jerry W; Plishker, Mary F; Saavedra, Claudia P; Chasteen, Thomas G; Vásquez, Claudio C Article Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry (2004)
Identification of biogenic organotellurides in Escherichia coli K-12 headspace gases using solid-phase microextraction and gas chromatography Swearingen Jr. J.W.; Plishker M.F.; Chasteen, T. G.; Araya M.A.; Saavedra, C. P.; Vasquez, C. C. Article SCOPUS ANALYTICAL BIOCHEMISTRY (2004)
Identification of biogenic organotellurides in Escherichia coli K-12 headspace gases using solid-phase microextraction and gas chromatography. Swearingen, Jerry W; Araya, Manuel A; Plishker, Mary F; Saavedra, Claudia P; Vásquez, Claudio C; Chasteen, Thomas G Article Analytical biochemistry (2004)
Qutrit quantum computer with trapped ions Klimov, AB; Guzman, R; RETAMAL, JC; SAAVEDRA, C Article ISI SCOPUS PHYSICAL REVIEW A (2003)
The Geobacillus stearothermophilus V iscS gene, encoding cysteine desulfurase, confers resistance to potassium tellurite in Escherichia coli K-12 Tantalean, JC; Araya, MA; Saavedra, CP; Fuentes DE; Perez, JM; Calderon, IL; Youderian, P; Vásquez CC Article ISI SCOPUS JOURNAL OF BACTERIOLOGY (2003)
The Geobacillus stearothermophilus V iscS gene, encoding cysteine desulfurase, confers resistance to potassium tellurite in Escherichia coli K-12. Tantaleán, Juan C; Araya, Manuel A; Saavedra, Claudia P; Fuentes, Derie E; Pérez, José M; Calderón, Iván L; Youderian, Philip; Vásquez, Claudio C Article Journal of bacteriology (2003)
Entanglement purification in cavity QED using local operations Romero, JL; Roa L.; RETAMAL, JC; SAAVEDRA, C Article ISI SCOPUS PHYSICAL REVIEW A (2002)
Experimental analysis and simplified modelling of a hermetic scroll refrigeration compressor Winandy, E; SAAVEDRA, C; Lebrun, J Article ISI SCOPUS APPLIED THERMAL ENGINEERING (2002)
Expression of Bacillus stearothermophilus LV cadmium resistance genes in Escherichia coli causes hypersensitivity to cadmium chloride Nerey, MD; Pichuantes, SE; Saavedra, CP; Araya, MA; Tantalean, JC; Vásquez CC Article ISI SCOPUS CURRENT MICROBIOLOGY (2002)
Expression of Bacillus stearothermophilus LV cadmiun resistance genes in Escherichia coli causes hypersensitivity to cadmiun chloride. Nerey, M., Pichuantes, S., Saavedra, C., Araya, M., Vásquez, C. Article Curr. Microbiol. (2002)
Quantum entanglement purification in cavities Romero, JL; RETAMAL, JC; Roa L.; SAAVEDRA, C Article ISI REVISTA MEXICANA DE FISICA (2002)
General properties of quantum systems interacting with a field mode in a low-Q cavity Klimov, AB; Romero, JL; SAAVEDRA, C Article ISI PHYSICAL REVIEW A (2001)
The product of the cysK gene of Bacillus stearothermophilus V mediates potassium tellurite resistance in Escherichia coli. Vásquez, C C; Saavedra, C P; Loyola, C A; Araya, M A; Pichuantes, S Article Current microbiology (2001)
Controlled source of entangled photonic qubits SAAVEDRA, C; Gheri, KM; Torma, P; Cirac, JI; Zoller, P Article ISI SCOPUS PHYSICAL REVIEW A (2000)
Dispersive atomic evolution in a dissipative-driven cavity Chumakov, SM; Klimov, AB; SAAVEDRA, C Article ISI SCOPUS PHYSICAL REVIEW A (2000)
Nucleotide sequence of the gene encoding the BstLVI DNA methyltransferase: Comparison with other amino-DNA methyltransferases Vásquez CC; Saavedra, CP; Pichuantes, SE Article ISI SCOPUS CURRENT MICROBIOLOGY (2000)
Nucleotide sequence of the gene encoding the BstLVI DNA methyltransferase: comparison with other amino-DNA methyltransferases. Vásquez, C C; Saavedra, C P; Pichuantes, S E Article Current microbiology (2000)
Cloning of a tellurite resistance determinant from Bacillus stearothermophilus V in Escherichia coli. Vásquez, C; Saavedra, C; Loyola, C; Moscoso, H; Pichuantes, S Article Biochemistry and molecular biology international (1999)
Structural studies of the BstVI restriction-modification proteins by fluorescence spectroscopy. Saavedra, C; Vásquez, C; Encinas, M V Article European journal of biochemistry / FEBS (1999)
The amino acidic substitution of cysteine 167 by serine (C167S) in BstVI restriction endonuclease of Bacillus stearothermophilus V affects its conformation and thermostability. Loyola, C; Saavedra, C; Gómez, I; Vásquez, C Article Biochimie (1999)
Biochemical characterization of tellurite-reducing activities of Bacillus stearothermophilus V. Moscoso, H; Saavedra, C; Loyola, C; Pichuantes, S; Vásquez, C Article Research in microbiology (1998)
Studies on the heterologous expression of BstVI restriction endonuclease in Escherichia coli. Saavedra, C; González, E; Vásquez, C Article Biochemistry and molecular biology international (1998)
Cloning and expression of the bstLVIM gene from Bacillus stearothermophilus LV in Escherichia coli: purification and characterization of the M.bstLVI DNA methyltransferase. Vásquez, C.; Saavedra, C.; González, E.; Lobos, C. Article As. Pac. J. Mol. Biol. Biothecnol. (1994)
The expression of the bstVIM gene from Bacillus stearothermophilus V is restricted to vegetative cell growth. González, E; Padilla, C; Saavedra, C; Vásquez, C Article Microbiology (Reading, England) (1994)
Plasmidios de resistencia a antibioticos en Shigella sonnei y Shigella flexneri, transferencia a Escherichia coli Padilla, C.; Alvarez, M.; Saavedra, C.; Vasquez, C.; González, E. Article Anal. Microbiol. (1993)
Cloning the BstVI restriction-modification system in Escherichia coli. Vásquez, C; Saavedra, C; González, E Article Gene (1991)
Affinity labeling of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase with the 2',3'-dialdehyde derivative of ATP. Saavedra, C; Araneda, S; Cardemil, E Article Archives of biochemistry and biophysics (1988)


Permeability and localization of nitroxide pre-fluorescent probes in epithelial cells Aspée A.; Bar-Magen, T; Villareal, JM; Mikelsons, L; SAAVEDRA, C; Scaiano, JC Abstract ISI FREE RADICAL RESEARCH (2007)


Fusion of neural gas Moreno, S.; Allende, H.; Salas, R.; SAAVEDRA, C ConferencePaper ISI BIO-INSPIRED SYSTEMS AND APPLICATIONS: FROM ROBOTICS TO AMBIENT INTELLIGENCE, PT II (2007)


Comparison of molecular regulation strategies for two bacterial lifestyle models in response to niche oxidative stress challenges ECOS-CONICYT (170023) Proyecto 2018-2020 Inv. Principal
Evaluación de mecanismos de resistencia presentes en microorganismos que prosperan en ambientes naturales con arsénico=> caso del género Exiguobacterium en el Salar de Huasco. Universidad Andrés Bello (DI-3-17/N) Proyecto 2017-2019 Inv. Principal
Evaluación de mecanismos de resistencia presentes en microorganismos que prosperan en ambientes naturales con arsénico=> caso del género Exiguobacterium en el Salar de Huasco. Universidad Andres Bello (Núcleo UNAB 2017) Proyecto 2017-2019 Inv. Responsable
Identification and characterization of non-cognate partners of the Salmonella Typhimurium ArcAB two-component system in response to hydrogen peroxide and hypochlorous acid FONDECYT (1160315) Proyecto 2016-2019 Inv. Responsable
Identification and characterization of non-cognate partners of the Salmonella Typhimurium ArcAB two-component system in response to hydrogen peroxide and hypochlorous acid. Saavedra, Claudia Paz Proyecto (2016)
Clarify the role of the two-ArcAB components in response to NaOCl Universidad Andrés Bello (UNAB DI-786-15/R) Proyecto 2015-2016 Inv. Responsable
ROLE OF THE SALMONELLA TYPHIMURIUM CYSJIH OPERON AND CYSTEINE DESULFHYDRASE METC IN THE RESPONSE TO BACTERICIDAL ANTIBIOTIC-DERIVED ROS=> HYDROGEN SULFIDE ACCUMULATION AS A MECHANISM OF RESISTANCE FONDECYT (1130074) Proyecto 2013-2016 Coinvestigador(a)
ArcA and SlyA-mediated response to radical oxygen species in Salmonella. FONDECYT (1120384) Proyecto 2012-2015 Inv. Responsable
ARCA AND SLYA-MEDIATED RESPONSE TO RADICAL OXYGEN SPECIES IN SALMONELLA FONDECYT (1120384) Proyecto 2012-2016 Inv. Responsable
IDENTIFICATION AND ANALYSIS OF PSEUDOGENES INVOLVED IN THE EVOLUTIONARY ADAPTATION OF SALMONELLA TYPHI TO THE HUMAN HOST FONDECYT (1110120) Proyecto 2011-2015 Coinvestigador(a)
Identification and analysis of pseudogenes involves in the evolutionary adaptation of Salmonella Typhi to the humnan host. FONDECYT (1100120) Proyecto 2011-2013 Coinvestigador(a)
Down-regulation of the porins expresión in Salmonella enterica serovar Typhimurium on oxidative. FONDECYT (3095013) Proyecto 2009-2011 Inv. Patrocinante
Participación de las porinas de Salmonella enterica serovar Typhimurium en la expulsión de moléculas derivadas del estrés oxidativo. Universidad Andres Bello (DI-50-09/R UNAB.) Proyecto 2009-2010 Inv. Responsable
LAS PORINAS OMPW, OMPD Y OMPL DE SALMONELLA ENTERICA SEROVAR TYPHIMURIUM CONTRIBUYEN A LA HOMEOSTASIS DEL PERIPLASMA Y A LA SUPERVIVENCIA DE LA BACTERIA EN EL HOSPEDERO. FONDECYT (1085131) Proyecto 2008-2012 Inv. Responsable
Nitroxides prefluorescent probles on the free radical monitoring in proteins, monolayers and cells. FONDECYT (1085177) Proyecto 2008-2011 Coinvestigador(a)
Caracterización bioquímica de las proteínas de membrana externa, OmpD y OmpW de Salmonella enterica serovar Typhimurium. DI-UNAB. Proyecto 2007-2008 Inv. Responsable
SALMONELLA ENTERICA SEROVAR Typhi, PATOGENO ESPECIFICO Y CRONICO DEL SER HUMANO=> CARACTERIZACION DE MECANISMOS MOLECULARES DE SU PATOGENICIDAD. FONDECYT (1060999) Proyecto 2006-2010 Coinvestigador(a)
Salmonella enterica serovar Typhi, patógeno específico y cróncio del ser humano=> caracterización de mecanismos moleculares de su patogenecidad. FONDECYT (1060999) Proyecto 2006-2010 Coinvestigador(a)
La proteína OmpW de Salmonella enterica serovar Typhimurium, participa en la expulsión de metil viológeno desde la célula. DI-UNAB. Proyecto 2005-2006 Inv. Responsable
PARTICIPACION DE LAS PROTEINAS DE MEMBRANA EXTERNA OMPD Y OMPW DE SALMONELLA ENTERICA SEROVAR TYPHIMURIUM EN LA EXPULSION DE SUSTANCIAS TOXICAS DESDE LA CELULA FONDECYT (1050037) Proyecto 2005-2008 Inv. Responsable
Participación de las proteínas de membrana externa OmpD y OmpW de Salmonella enterica serovar Typhimurium en la expulsión de sustancias tóxicas desde la célula. FONDECYT (1050037) Proyecto 2005-2007 Inv. Responsable
REACCIONES DE TRANSFERENCIA DE HIDROGENO DESDE ANTIOXIDANTES A RADICALES NITROXIDO EN SISTEMAS DE INTERES BIOLOGICO. FONDECYT (1050137) Proyecto 2005-2008 Coinvestigador(a)
Reacciones de transferencia de hidrógeno desde antioxidantes a radicales nitróxido en sistemas de interés biológico. FONDECYT (1050137) Proyecto 2005-2007 Coinvestigador(a)
RESISTENCIA BACTERIANA A TELURITO DE POTASIO=> ESTUDIO DE LA PARTICIPACION DE GENES DEL METABOLISMO DE LA CISTEINA DE BACILLUS STEAROTHERMOPHILUS V. FONDECYT (1030234) Proyecto 2003-2006 Coinvestigador(a)
Resistencia bacteriana a telurito de potasio=> estudio de la participación de genes del metabolismo de la cisteína de Bacillus stearothermophilus V. FONDECYT (1030234) Proyecto 2003-2005 Coinvestigador(a)
Estudios estructurales de la cisteína sintetasa de Bacillus stearothermophilus V=> Participación del extremo carboxilo terminal en la funcionalidad de la enzima. Proyecto Dicyt. Universidad de Santiago. Proyecto 2002-2004 Inv. Responsable
Estudio sobre las bases moleculares de la resistencia a telurito de potasio en Bacillus stearothermophilus V. FONDECYT (1990917) Proyecto 1999-2001 Coinvestigador(a)
ESTUDIO SOBRE LAS BASES MOLECULARES DE LA RESISTENCIA A TELURITO DE POTASIO EN BACILLUS STEAROTHERMOPHILUS V. FONDECYT (1990917) Proyecto 1999-2002 Coinvestigador(a)
Estudios moleculares sobre la resistencia a telurito de potasio en Bacillus stearothermophilus V. Universidad de Santiago de Chile. Proyecto Dicyt (9843VG) Proyecto 1998-2000 Coinvestigador(a)
IDENTIFICACION Y ANALISIS DE DOMINIOS FUNCIONALES EN LAS ENZIMAS DEL SISTEMA DE RESTRICCION-MODIFICACION BSTVI DE BACILLUS STEAROTHERMOPHILUS V FONDECYT (1950440) Proyecto 1995-1998 Coinvestigador(a)
Identificación y análisis de dominios funcionales en las enzimas del sistema de restricción-modificación BstVI de Bacillus stearothermophilus V. FONDECYT (0440-95) Proyecto 1995-1997 Coinvestigador(a)
Localización de sitios funcionales en la endonucleasa de restricción BstVI. Universidad de Santiago Proyecto Dicyt Proyecto 1995-1998 Coinvestigador(a)
AUTORESTRICCION DEL DNA CROMOSOMAL EN BACTERIAS=> ESTUDIOS DE LOS MECANISMOS DEL PROTECCION ADICIONAL A LA MODIFICACION DEL DNA POR METILACION FONDECYT (1920151) Proyecto 1992-1995 Coinvestigador(a)
Autorestricción del DNA cromosomal en bacterias=> estudios de los mecanismos de protección adicionales a la modificación del DNA por metilación. FONDECYT (0151) Proyecto 1992-1995 Coinvestigador(a)
REGULACION DE LA EXPRESION GENICA DEL SISTEMA DE MODIFICACION RESTRICCION DE BACILUS STEAROTHERMOPHILUS Y SU RELACION CON EL PROCESO DE ESPORULACION FONDECYT (1910127) Proyecto 1991-1993 Coinvestigador(a)
Regulación de la expresión génica del sistema de modificación-restricción de Bacillus stearothermophilus V y su relación con el proceso de esporulación FONDECYT (0127) Proyecto 1991-1992 Coinvestigador(a)
CARACTERIZACION ESTRUCTURAL Y BIOQUIMICA DEL SISTEMA DE MODIFICACION- RESTRICCION DE BACILLUS STEAROTHERMOPHILUS V. FONDECYT (1890003) Proyecto 1989-1992 Coinvestigador(a)
Caracterización estructural y bioquímica del sistema de modificación- restricción de Bacillus stearothermophilus V. FONDECYT (003/89) Proyecto 1989-1991 Coinvestigador(a)


Two-photon high-dimensional spatial entanglement: Theory and experiment Neves L.; Lima G.; Gomez, JGA; Monken, CH; SAAVEDRA, C; Padua, S. Review ISI MODERN PHYSICS LETTERS B (2006)

Claudia Saavedra

Full Professor

Departmento de Ciencias de la Vida

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

Carlos Saavedra

Full Professor

Physics

Universidad de Concepcion

Concepción, Chile

IVAN CALDERON

Associate Professor / Principal Investigator/ Master in Biotechnology & Life Sciences Director

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO

SANTIAGO, Chile

Fernando Gil

Associate Professor

Biological Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Coral Pardo

Investigador postdoctoral

Universidad Católica del Norte

antofagasta, Chile

Juan Castro

Post-Doctorante

Universidad Católica del Norte

Antofagasta, Chile

EDUARDO HUGO MORALES SIERRA

Juan Retamal

Full Professor

Physics

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago de CHile, Chile

Alejandro Hidalgo

Associate Professor

Escuela de Química y Farmacia

Universidad Andres Bello

Santiago, Chile

Derie Fuentes

Director

Center For Systems Biotechnology

Universidad Andrés Bello

Santiago, Chile

Guido Mora

Académico/Investigador

Facultad Ciencias de la Salud

Universidad SEK

Santiago, Chile

FRANCISCO REMONSELLEZ

Professor

Ingenieria Química

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

Luis Roa

Full Professor

Fisica

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Alan Briones

Bioquímico Clínico

Hospital San Juan de Dios

Santiago, Chile

Eduardo Castro

Professor

Departamento de Microbiología

Universidad de Talca

Talca, Chile

Héctor Allende

Professor

Computer Science

UNIVERSIDAD TÉCNICA FEDERICO SANTA MARÍA

Valparaíso, Chile

Rodrigo Salas

Profesor Titular Jornada Completa

UNIVERSIDAD DE VALPARAÍSO

Valparaíso, Chile

Juan Fuentes

Académico

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

Gabriel Krüger

Investigador Doctoral

Universidad Andrés Bello

Santiago Centro, Chile

Gustavo Moreira

Full Professor

Physics

UNIVERSIDAD DE CONCEPCIÓN

Concepción, Chile

Carolina Saavedra

Profesora Adjunta

Facultad de Ingeniería

Universidad de Valparaíso

Valparaíso, Chile

Daniel Aguayo

Associate Professor

ITISB

UNIVERSIDAD ANDRES BELLO

Viña del Mar, Chile

José Pérez

Associate Professor

Biologia

Universidad Andres Bello

Santiago, Chile

Carolina Cabezas

Roberto Luraschi

Asistente de investigación

Departamento de biología

Universidad de Santiago de Chile

Santiago, Chile

Sebastian Moreno

Profesor asociado

Ingeniería y ciencias

Universidad Adolfo Ibanez

Vina del Mar, Chile

Rubén Polanco

Associate Professor

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO (UNAB)

SANTIAGO, Chile

Pablo Aguilar

Academico

Departamento de Biotecnologia

Universidad de Antofagasta

Antofagasta, Chile

Arturo Fernández

Profesor Asociado

Departamento de Física

Universidad del Bío-Bío

Concepción, Chile

ALEXIS ASPEE

Profesor Titular

Ciencias del Ambiente

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

Claudio Meneses

Profesor Asociado

Facultad de Agronomía e Ingeniería Forestal/ Facultad de Ciencias Biológicas

Pontificia Universidad Católica de Chile

Santiago, Chile

Aldo Delgado

Full Professor

Department of Physics

Universidad de Concepción

Concepción, Chile

Nicolas Pacheco

PROFESOR ADJUNTO

CIENCIAS BIOLOGICAS

Universidad Andrés Bello

Santiago centro, Chile

Nicolás Villagra

Profesor Asistente

Tecnología Médica

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Mario Tello

Académico

Biología

Universidad de Santiago de Chile

Santiago, Chile

Felipe Arenas

Profesor Asociado

Biología

UNIVERSIDAD SANTIAGO DE CHILE

Santiago, Chile

Paulina Calderón

Investigador Principal

Biome Therapeutics

Santiago, Chile

Maria Opazo

Profesor Asociado

Universidad de Las Américas

Santiago, Chile

samuel parra

Investigador Postdoctoral

Biología Molecular

Universidad de Chile

Santiago, Chile

Ignacio Poblete

Professor

Chemical and Bioprocess Engineering

Universidad de Santiago de Chile

santiago, Chile

Sebastián Contreras

Doctoral Researcher

Neural Systems Theory

Max Planck Institute for Dynamics and Self-Organization

Göttingen, Alemania

Melissa Alegría

Académico Asociado

Facultad de Ingeniería y Negocios

Universidad de Las Américas

Santiago, Chile

Nelson Caro

Director de Centro

Centro de Investigación Austral Biotech

Universidad Santo Tomás

Santiago, Chile

Sergio Barahona

Fernando Gonzalez

Titular Professor

Facultad de Ciencias de la Vida

Universidad Andres Bello

Santiago, Chile

Alvaro Olivera

Principal Investigator and Assistant Professor

Chemical Engineering, Biotechnology and Materials

UNIVERSIDAD DE CHILE

Santiago, Chile

Raquel Quatrini

Research Associate

Fundación Ciencia & Vida

Santiago, Chile

Bárbara Fuentes

Acádemcia, Investigadora, Jefe de Carrera

Departamento de Ingeniería Química

UNIVERSIDAD CATÓLICA DEL NORTE

Antofagasta, Chile

Susan Bueno

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

David Medina

Assistant Professor

Departamento de Ingeniería en Computación

Universidad de Magallanes

Punta Arenas, Chile

Carlos Areche

ASSOCIATE PROFESSOR

CHEMISTRY

UNIVERSIDAD DE CHILE

Santiago, Chile

Claudio Vasquez

Full Professor

Biology Department

UNIVERSIDAD DE SANTIAGO DE CHILE

Santago, Chile

Maria Encinas

Full Professor

Enviroment Science

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

Gino Nardocci

Investigador / Profesor Asistente

Universidad de Los Andes

Santiago, Chile

Rodrigo Pacheco

Associate Investigator; Head of the Laboratory of Neuroimmunology

Fundación Ciencia para la Vida

Santiago, Chile

Maria Otero

Profesor Asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

Paulina Hidalgo

Asociated Professor

Organic Chemistry

UNIVERSIDAD DE CONCEPION

Concepcion, Chile

Ítalo Urrutia

Profesor Asistente

Universidad Autónoma de Chile

Santiago, Chile

Sandro Valenzuela

Bioinformático

Bioinformática

Multiplex SpA

Santiago, Chile

Jorge Valdes

PROFESOR ASOCIADO

CENTRO DE BIOINFORMÁTICA Y BIOLOGÍA INTEGRATIVA

Universidad Andrés Bello

Santiago, Chile

Daniel Paredes

Associate Professor

Department of Biological Sciences

Universidad Andrés Bello

Santiago, Chile

Claudia Paz Saavedra Sánchez

Líneas de Investigación

Educación

Biochemistry, UNIVERSIDAD DE CHILE. Chile, 2002

Biochemist, UNIVERSIDAD DE SANTIAGO DE CHILE. Chile, 1989

Masters in Biological Sciences with mention in Molecular and Cellular Biology, UNIVERSIDAD DE CHILE. Chile, 1997

Post-PhD Research, TEXAS A&M UNIVERSITY. Estados Unidos, 2003

Experiencia Académica

Postdoctoral student Full Time

Assistant professor Part Time

assistant professor Full Time

Full professor Full Time

Experiencia Profesional

Assistant professor Full Time

Associate professor Part Time

Biochemistry School Director Full Time

Academic microbiology area Part Time

Formación de Capital Humano

Difusión y Transferencia

Article (95)

Abstract (1)

ConferencePaper (1)

Proyecto (38)

Comparison of molecular regulation strategies for two bacterial lifestyle models in response to niche oxidative stress challenges

Evaluación de mecanismos de resistencia presentes en microorganismos que prosperan en ambientes naturales con arsénico=> caso del género Exiguobacterium en el Salar de Huasco.

Evaluación de mecanismos de resistencia presentes en microorganismos que prosperan en ambientes naturales con arsénico=> caso del género Exiguobacterium en el Salar de Huasco.

Identification and characterization of non-cognate partners of the Salmonella Typhimurium ArcAB two-component system in response to hydrogen peroxide and hypochlorous acid

Clarify the role of the two-ArcAB components in response to NaOCl

ROLE OF THE SALMONELLA TYPHIMURIUM CYSJIH OPERON AND CYSTEINE DESULFHYDRASE METC IN THE RESPONSE TO BACTERICIDAL ANTIBIOTIC-DERIVED ROS=> HYDROGEN SULFIDE ACCUMULATION AS A MECHANISM OF RESISTANCE

ArcA and SlyA-mediated response to radical oxygen species in Salmonella.

ARCA AND SLYA-MEDIATED RESPONSE TO RADICAL OXYGEN SPECIES IN SALMONELLA

IDENTIFICATION AND ANALYSIS OF PSEUDOGENES INVOLVED IN THE EVOLUTIONARY ADAPTATION OF SALMONELLA TYPHI TO THE HUMAN HOST

Identification and analysis of pseudogenes involves in the evolutionary adaptation of Salmonella Typhi to the humnan host.

Down-regulation of the porins expresión in Salmonella enterica serovar Typhimurium on oxidative.

Participación de las porinas de Salmonella enterica serovar Typhimurium en la expulsión de moléculas derivadas del estrés oxidativo.

LAS PORINAS OMPW, OMPD Y OMPL DE SALMONELLA ENTERICA SEROVAR TYPHIMURIUM CONTRIBUYEN A LA HOMEOSTASIS DEL PERIPLASMA Y A LA SUPERVIVENCIA DE LA BACTERIA EN EL HOSPEDERO.

Nitroxides prefluorescent probles on the free radical monitoring in proteins, monolayers and cells.

Caracterización bioquímica de las proteínas de membrana externa, OmpD y OmpW de Salmonella enterica serovar Typhimurium.

SALMONELLA ENTERICA SEROVAR Typhi, PATOGENO ESPECIFICO Y CRONICO DEL SER HUMANO=> CARACTERIZACION DE MECANISMOS MOLECULARES DE SU PATOGENICIDAD.

Salmonella enterica serovar Typhi, patógeno específico y cróncio del ser humano=> caracterización de mecanismos moleculares de su patogenecidad.

La proteína OmpW de Salmonella enterica serovar Typhimurium, participa en la expulsión de metil viológeno desde la célula.

PARTICIPACION DE LAS PROTEINAS DE MEMBRANA EXTERNA OMPD Y OMPW DE SALMONELLA ENTERICA SEROVAR TYPHIMURIUM EN LA EXPULSION DE SUSTANCIAS TOXICAS DESDE LA CELULA

Participación de las proteínas de membrana externa OmpD y OmpW de Salmonella enterica serovar Typhimurium en la expulsión de sustancias tóxicas desde la célula.

REACCIONES DE TRANSFERENCIA DE HIDROGENO DESDE ANTIOXIDANTES A RADICALES NITROXIDO EN SISTEMAS DE INTERES BIOLOGICO.

Reacciones de transferencia de hidrógeno desde antioxidantes a radicales nitróxido en sistemas de interés biológico.

RESISTENCIA BACTERIANA A TELURITO DE POTASIO=> ESTUDIO DE LA PARTICIPACION DE GENES DEL METABOLISMO DE LA CISTEINA DE BACILLUS STEAROTHERMOPHILUS V.

Resistencia bacteriana a telurito de potasio=> estudio de la participación de genes del metabolismo de la cisteína de Bacillus stearothermophilus V.

Estudios estructurales de la cisteína sintetasa de Bacillus stearothermophilus V=> Participación del extremo carboxilo terminal en la funcionalidad de la enzima.

Estudio sobre las bases moleculares de la resistencia a telurito de potasio en Bacillus stearothermophilus V.

ESTUDIO SOBRE LAS BASES MOLECULARES DE LA RESISTENCIA A TELURITO DE POTASIO EN BACILLUS STEAROTHERMOPHILUS V.

Estudios moleculares sobre la resistencia a telurito de potasio en Bacillus stearothermophilus V.

IDENTIFICACION Y ANALISIS DE DOMINIOS FUNCIONALES EN LAS ENZIMAS DEL SISTEMA DE RESTRICCION-MODIFICACION BSTVI DE BACILLUS STEAROTHERMOPHILUS V