Man

Guido Carlos Mora Longa

Académico/Investigador

Universidad SEK

Santiago, Chile

Líneas de Investigación


Educación

  •  Molecular Biology, UNIVERSITY OF WISCONSIN-MADISON. Estados Unidos, 1971
  •  Licenciado en Bioquímica y Bioquímico, UNIVERSIDAD DE CHILE. Chile, 1965

Experiencia Profesional

  •   Director Carrera Medicina Full Time

    Universidad Andres Bello

    Santiago, Chile

    2014 - 2019

Premios y Distinciones

  •   PREMIO

    ORGANIZACION PANAMERICA DE LA SALUD

    Chile, 1986

    Mejor trabajo científico presentado en el X Congreso de la Asociación Chilena de Microbiología,


 

Article (36)

Inactivation of Glutamine Synthetase-Coding Gene glnA Increases Susceptibility to Quinolones Through Increasing Outer Membrane Protein F in Salmonella enterica Serovar Typhi
Cysteine auxotrophy drives reduced susceptibility to quinolones and paraquat by inducing the expression of efflux-pump systems and detoxifying enzymes in S. Typhimurium
Xylose Improves Antibiotic Activity of Chloramphenicol and Tetracycline against K. pneumoniae and A. baumannii in a Murine Model of Skin Infection
Expression of IroN, the salmochelin siderophore receptor, requires mRNA activation by RyhB small RNA homologues
Lose to win: marT pseudogenization in Salmonella enterica serovar Typhi contributed to the surV-dependent survival to H2O2, and inside human macrophage-like cells
SPI-9 of Salmonella enterica serovar Typhi is constituted by an operon positively regulated by RpoS and contributes to adherence to epithelial cells in culture
Theoretical and experimental characterization of a novel pyridine benzimidazole: suitability for fluorescence staining in cells and antimicrobial properties
Pseudogenization of sopA and sopE2 is functionally linked and contributes to virulence of Salmonella enterica serovar Typhi
Spectral, theoretical characterization and antifungal properties of two phenol derivative Schiff bases with an intramolecular hydrogen bond
stg fimbrial operon from S. Typhi STH2370 contributes to association and cell disruption of epithelial and macrophage-like cells
Draft Genome Sequence of Salmonella enterica Serovar Typhi Strain STH2370
RpoS integrates CRP, Fis, and PhoP signaling pathways to control Salmonella Typhi hlyE expression
Salmonella Typhi shdA: Pseudogene or allelic variant?
Porin alterations present in non-carbapenemase-producing Enterobacteriaceae with high and intermediate levels of carbapenem resistance in Chile
Synthesis of CdTe QDs/single-walled aluminosilicate nanotubes hybrid compound and their antimicrobial activity on bacteria
The carbon source influences the efflux pump-mediated antimicrobial resistance in clinically important Gram-negative bacteria
A holin remnant protein encoded by STY1365 is involved in envelope stability of Salmonella enterica serovar Typhi
Response regulator ArcA of Salmonella enterica serovar Typhimurium downregulates expression of OmpD, a porin facilitating uptake of hydrogen peroxide
Modified Intracellular-Associated Phenotypes in a Recombinant Salmonella Typhi Expressing S. Typhimurium SPI-3 Sequences
S. Typhimurium sseJ gene decreases the S. Typhi cytotoxicity toward cultured epithelial cells
Salmonella enterica serovar Typhi has a 4.1 kb genetic island inserted within the sapABCDF operon that causes loss of resistance to the antimicrobial peptide protamine
Characterization of MgtC, a Virulence Factor of Salmonella enterica Serovar Typhi
RpoS- and Crp-dependent transcriptional control of Salmonella Typhi taiA and hlyE genes: role of environmental conditions
SmvA, and not AcrB, is the major efflux pump for acriflavine and related compounds in Salmonella enterica serovar Typhimurium
The capacity of Salmonella to survive inside dendritic cells and prevent antigen presentation to T cells is host specific
The Salmonella Typhi hlyE gene plays a role in invasion of cultured epithelial cells and its functional transfer to S. Typhimurium promotes deep organ infection in mice
The ompW (porin) gene mediates methyl viologen (paraquat) efflux in Salmonella enterica serovar Typhimurium
The cotranscribed Salmonella enterica sv. Typhi tsx and impX genes encode opposing nucleoside-specific import and export proteins
Genetic analysis of antibiotic-resistance determinants in multidrug-resistant Shigella strains isolated from Chilean children
The Salmonella enterica serovar Typhi tsx gene, encoding a nucleoside-specific porin, is essential for prototrophic growth in the absence of nucleosides
Insertions of mini-Tn10 transposon T-POP in Salmonella enterica sv. typhi
Precise Excision of the Large Pathogenicity Island, SPI7, in Salmonella enterica Serovar Typhi
Global regulation of the Salmonella enterica serovar Typhimurium major porin, OmpD
Prophage contribution to bacterial population dynamics
The Salmonella enterica sv. Typhimurium smvA, yddG and ompD (porin) genes are required for the efficient efflux of methyl viologen
A chromosomal region surrounding the ompD porin gene marks a genetic difference between Salmonella typhi and the majority of Salmonella serovars

BookSection (1)

Unnecessary baggage

Proyecto (6)

Loss of key functions drive Salmonella Typhi adaptive pathogenesis to humans
Formulación de un Compuesto Farmacéutico efectivo contra Bacterias Multirresistente de Importancia Médica
Identification and analysis of pseudogenes involved in the evolutionary adaptation of Salmonella Typhi to the human host
Salmonella enterica serovar Typhi, patógeno específico y crónico del ser humano: Caracterización de mecanismos moleculares de su patogenicidad
Participación de las proteínas de membrana externa OmpD y OmpW de Salmonella enterica serovar Typhimurium en la expulsión de sustancias toxicas desde la célula
Genómica funcional en Salmonella Typhi: Evaluación del rol de regiones cromosomales serovar-específicas en patogenicidad y especificidad de hospedero
43
Guido Mora

Académico/Investigador

Facultad Ciencias de la Salud

Universidad SEK

Santiago, Chile

18
Juan Fuentes

Académico

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

14
Nicolás Villagra

Profesor Asistente

Tecnología Médica

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

10
Alejandro Hidalgo

Associate Professor

Escuela de Química y Farmacia

Universidad Andres Bello

Santiago, Chile

6
Claudia Saavedra

Full Professor

Departmento de Ciencias de la Vida

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

4
Paula Rodas

Scientific affairs

Agencia Chilena para la Inocuidad Alimentaria (ACHIPIA)

Santiago, Chile

4
Matías Jofré

Académico

Universidad Finis Terrae

Santiago, Chile

3
Ítalo Urrutia

Profesor Asistente

Universidad Autónoma de Chile

Santiago, Chile

3
Susan Bueno

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

3
Liliana Berrocal

Académico

UNIVERSIDAD FINIS TERRAE

Santiago, Chile

3
Ramiro Arratia

DIRECTOR DOCTORADO

CIENCIAS QUIMICAS

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

3
Mario Castillo

Coordinador área Microbiología e Inmunología

Ciencias Químicas y Biológicas

Universidad Bernardo O'Higgins

Santiago, Chile

3
Fernando Gil

Associate Professor

Biological Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

3
SERGIO BUCAREY

Profesor Asociado

Departamento de Ciencias Biológicas Animales

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS

Santiago, Chile

3
Patricia García

Jefe de Laboratorio de Microbiologia

Escuela de Medicina

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE, LABORATORIO DE MICROBIOLOGÍA

Santiago, Chile

3
IVAN CALDERON

Associate Professor / Principal Investigator/ Master in Biotechnology & Life Sciences Director

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO

SANTIAGO, Chile

2
Daniel Paredes

Associate Professor

Department of Biological Sciences

Universidad Andrés Bello

Santiago, Chile

2
Alexander Carreño

Profesor asistente

Doctorado en Fisico Química Molecular

Universidad Andrés Bello

Santiago, Chile

2
Alexander Carreño

Profesor asistente

Center of Applied Nanoscience

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2
Patricio Retamal

Profesor Asistente

Medicina Preventiva Animal

FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS, UNIVERSIDAD DE CHILE

Santiago, Chile

2
Manuel Gacitúa

Profesor asistente

Departamento de Química de los Materiales

Universidad de Santiago de Chile

Santiago, Chile

1
Juan Castro

Researcher

Universidad de Chile

Santiago, Chile

1
Marcelo Preite

Associate Professor

Organic Chemistry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Pablo González

Associate Professor

Molecular Genetics and MIcrobiology

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Aniela Wozniak

Coordinador de Investigación

Dept Laboratorios Clínicos

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Rubén Polanco

Associate Professor

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO (UNAB)

SANTIAGO, Chile

1
Leandro Carreño

Profesor Asistente

Instituto de Ciencias Biomédicas

Universidad de Chile

Santiago, Chile

1
Alexis Kalergis

Full Professor

Microbiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

1
Maria Otero

Profesor Asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Annette Trombert

Directora de Escuela

Biotecnología

UNIVERSIDAD MAYOR, INSTITUTO DE BIOTECNOLOGÍA, CENTRO DE GENÓMICA Y BIOINFORMÁTICA

Santiago, Chile

1
Nicolás Arancibia

Profesor Asistente

Universidad de Santiago

Santiago, Chile

1
Dayán Páez

Profesor Asociado

Facultad de Ciencias Exactas

Universidad Andrés Bello

Santiago, Chile

1
Nelson Caro

Director de Centro

Centro de Investigación Austral Biotech

Universidad Santo Tomás

Santiago, Chile

1
Marco Soto

Profesor Asociado

Química Física

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Niurka Navarro

Gerente

Innovación y Desarrollo

Nutri-Omics SpA

Samtiago, Chile

1
ALEXIS ASPEE

Profesor Titular

Ciencias del Ambiente

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Mauricio Farfán

Profesor Asociado

Departamento de Pediatria y Cirugia Infantil, Hospital Dr. Luis Calvo Mackenna, Facultad de Medicina, Universidad de Chile

Universidad de Chile

Providencia, Chile