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Paula Ivonne Rodas Garrido

Scientific affairs

Agencia Chilena para la Inocuidad Alimentaria (ACHIPIA)

Santiago, Chile

Líneas de Investigación


Antimicrobial resistance (AMR) in Foodborne diseases Mycotoxins and Food safety AMR in Healthcare-associated infections (HAI) Neisseria gonorrhoeae, genital microbiota, Sexually-transmitted infections (STIs)

Educación

  •  Bachelor, Universidad de Chile. Chile, 2003
  •  Biochemist, Universidad de Chile. Chile, 2005
  •  Ph.D, Universidad de Chile. Chile, 2012

Experiencia Académica

  •   Instructor Part Time

    Universidad de Santiago de Chile

    Chemistry and Biology

    Santiago, Chile

    2011 - 2012

  •   Assistant Professor Full Time

    Universidad Andrés Bello

    Medicine

    Santiago, Chile

    2012 - 2017

  •   Postdoctoral Fellow Part Time

    University of Southampton

    Medicine

    Southampton, Reino Unido

    2012 - 2013

  •   Principal Investigator /Assistant Professor Full Time

    UNIVERSIDAD ANDRES BELLO

    Medicine

    Concepción, Chile

    2018 - 2019

  •   Research Associate Full Time

    UNIVERSIDAD MAYOR

    CIENCIAS

    Santiago, Chile

    2019 - 2021

Experiencia Profesional

  •   Research Assistant Full Time

    FONDAP-Centro de Estudios Moleculares de la Célula- Facultad de Medicina, Universidad de Chile

    Santiago, Chile

    2005 - 2006

  •   Principal investigator REDI170370 grant Other

    PCI-CONICYT

    Chile

    2018 - 2019

  •   Principal Investigator FONDECYT 11121262 Other

    FONDECYT

    Chile

    2013 - 2016

  •   Postdoctoral Fellow WT090301 Full Time

    Wellcome Trust

    Southampton, Reino Unido

    2012 - 2013

  •   Visiting Professor Other

    Julius-Maximilians-Universität Würzburg

    Alemania

    2014 - 2014

  •   Microbiology consultant Full Time

    Pan American Health Organization (PAHO-Chile)

    Santiago, Chile

    2021 - 2024

  •   Academic pannel Other

    Agencia Nacional de Investigación y Desarrollo (ANID)

    Santiago, Chile

    2019 - 2024

  •   Scientific affairs - Food Microbiology Full Time

    Agencia Chilena para la Inocuidad y Calidad Alimentaria (ACHIPIA)

    Santiago, Chile

    2024 - A la fecha

Formación de Capital Humano


Thesis supervision:

- Master in Biochemistry: 1
- Master in Biotechnology: 2
- Internships: 20


Premios y Distinciones

  •   National Doctorate Fellowship

    COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

    Chile, 2006

    Fellowship to obtain a Ph.D degree in the University of Chile

  •   Travel Grant GDEST

    Ministerio da Ciencia e Tecnologia do Brasil

    Brasil, 2006

    Travel grant to attend the Global Dialogues on Emerging Science An Technology (GDEST) - Conference on Bioinformatics Funded by Ministerio da Ciencia e Tecnologia do Brasil and The Office of the Science and Technology Adviser to the Secretary of States - USA

  •   Grant for development of Doctoral Thesis

    COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

    Chile, 2008

    Grant for funding consumables and reagents in doctoral thesis

  •   Global Health Travel Award

    BILL AND MELINDA GATES FOUNDATION

    Estados Unidos, 2008

    Travel grant to fund attendance to the conference D4: Molecular Evolution as a Driving Force in Infectious Diseases Meeting (Keystone Symposia Global Health Series). 08-13 April 2008, Breckenridge (CO), USA.

  •   Youth Travel Fellowship

    Federation of European Biochemical Societies (FEBS)

    Reino Unido, 2010

    Travel grant to fund the attendance to the EMBO/FEBS Lecture Course 2010 ‘Host-Microbes Interactions’. 01-09 September 2010, Island of Spetses, Greece.

  •   Oriana Josseau Award

    Oriana Josseau Foundation

    Chile, 2010

    Award to the 2010 best female student of the Ph.D of Biochemistry Program, Faculty of Chemical Sciences, University of Chile


 

Article (27)

Carbapenem-resistant hypervirulent ST23 <i>Klebsiella pneumoniae</i> with a highly transmissible dual-carbapenemase plasmid in Chile
Caracterización fenotípica y molecular de cepas de Klebsiella pneumoniae productores de carbapenemasas tipo OXA-48 circulantes en Chile
Macrophage-Neisseria gonorrhoeae Interactions: A Better Understanding of Pathogen Mechanisms of Immunomodulation
Microbiological characterisation of the colonisation by Candida sp in patients with orthodontic fixed appliances and evaluation of host responses in saliva
Protective effect of inactivated blastoconidia in keratinocytes and human reconstituted epithelium against C. albicans infection
Differential Antifungal Activity of Human and Cryptococcal Melanins with Structural Discrepancies
Genotyping and Persistence of Candida albicans from Pregnant Women with Vulvovaginal Candidiasis
Modified profile of matrix metalloproteinase-2 and -9 production by human Fallopian tube epithelial cells following infection in vitro with Neisseria gonorrhoeae
Neisseria gonorrhoeae Challenge Increases Matrix Metalloproteinase-8 Expression in Fallopian Tube Explants
A feed-forward loop between SroC and MgrR small RNAs modulates the expression of eptB and the susceptibility to polymyxin B in Salmonella Typhimurium
ATP Induces IL-1 beta Secretion in Neisseria gonorrhoeae-Infected Human Macrophages by a Mechanism Not Related to the NLRP3/ASC/Caspase-1 Axis
Characterization of the Adherence of Clostridium difficile Spores: The Integrity of the Outermost Layer Affects Adherence Properties of Spores of the Epidemic Strain R20291 to Components of the Intestinal Mucosa
Increased PD-L1 expression and PD-L1/CD86 ratio on macrophages infected with Neisseria gonorrhoeae contributes to the functional suppression of T-cell responses
Lose to win: marT pseudogenization in Salmonella enterica serovar Typhi contributed to the surV-dependent survival to H2O2, and inside human macrophage-like cells
Salmonella Typhimurium exhibits fluoroquinolone resistance mediated by the accumulation of the antioxidant molecule H2S in a CysK-dependent manner
The NarE protein of Neisseria gonorrhoeae catalyzes ADP-ribosylation of several ADP-ribose acceptors despite an N-terminal deletion
Motility modulation by the small non-coding RNA SroC in Salmonella Typhimurium
Neisseria gonorrhoeae Modulates Immunity by Polarizing Human Macrophages to a M2 Profile
Participation of S. Typhimurium cysJIH Operon in the H2S-mediated Ciprofloxacin Resistance in Presence of Sulfate as Sulfur Source
Preclinical Development and In Vivo Efficacy of Ceftiofur-PLGA Microparticles
Evaluation of ceftiofur-PHBV microparticles in rats
Temporal and spatial regulation of cAMP signaling in disease: role of cyclic nucleotide phosphodiesterases
Neisseria gonorrhoeae Pilus Attenuates Cytokine Response of Human Fallopian Tube Explants
A holin remnant protein encoded by STY1365 is involved in envelope stability of Salmonella enterica serovar Typhi
Reduced invasion to human epithelial cell lines of Salmonella enterica serovar Typhi carrying S. Typhimurium sopD2
Salmonella enterica serovar Typhi has a 4.1 kb genetic island inserted within the sapABCDF operon that causes loss of resistance to the antimicrobial peptide protamine
Precise Excision of the Large Pathogenicity Island, SPI7, in Salmonella enterica Serovar Typhi

BookSection (2)

Use of Human Fallopian Tube Organ in Culture (FTOC) and Primary Fallopian Tube Epithelial Cells (FTEC) to Study the Biology of Neisseria gonorrhoeae Infection.
Use of Human Monocyte-Derived Macrophages to Study Neisseria Gonorrhoeae Infection

Proyecto (14)

Exploring the programmed cell death-ligand (PD-L1) in Neisseria gonorrhoeae-infected macrophages and the use of anti-PD-L1 therapy as novel approach to the treatment of gonorrhea in the era of antimicrobial resistance
Red Internacional para el estudio de la interacción bacteria-hongo oportunista entre Neisseria gonorrhoeae y Candida albicans y su influencia en la colonización del hospedero humano
Exploring the NLRP3 inflammasome pathway following infection of human Fallopian tube epithelial cells with Neisseria gonorrhoeae
Club de Ciencia Liceo La Granja, Santiago
Modification of activity profile of human metalloproteases MMP-2 and MMP-9 upon infection of primary human Fallopian tube epithelial cells by Neisseria gonorrhoeae
Production of silver nanoparticles with antibacterial activity using fungal biosynthesis
Study of the in vitro ADP-ribosyltransferase activity of the NarE toxin of the human pathogen Neisseria gonorrhoeae onto human antimicrobial peptides
The role of cellular adhesion proteins during in vitro Fallopian tubes infection by Neisseria gonorrhoeae
ROLE OF THE ADP-RIBOSYLTRANSFERASE TOXIN NARE IN ACTIN CYTOSKELETON REMODELING DURING THE INVASION OF THE HUMAN FALLOPIAN TUBE EPITHELIUM BY NEISSERIA GONORRHOEAE
The role of newly identified proteins with gelatinase activity expressed in human Fallopian tubes after infection with Neisseria gonorrhoeae
Beca de Apoyo a la Realización de Tesis Doctoral
SALMONELLA ENTERICA SEROVAR Typhi, PATOGENO ESPECIFICO Y CRONICO DEL SER HUMANO=> CARACTERIZACION DE MECANISMOS MOLECULARES DE SU PATOGENICIDAD.
Centro de Estudios Moleculares de la Célula (CEMC), Facultad de Medicina, Universidad de Chile
GENOMICA FUNCIONAL EN SALMONELLA TYPHI=> EVALUACION DEL ROL DE REGIONES CROMOSOMALES "SEROVAR-ESPECIFICAS" EN PATOGENICIDAD Y ESPECIFICIDAD DE HOSPEDERO.
26
Paula Rodas

Scientific affairs

Agencia Chilena para la Inocuidad Alimentaria (ACHIPIA)

Santiago, Chile

7
Juan Fuentes

Académico

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

5
Luis Velasquez

Director and Full Professor

Medicine

Universidad SEK

Santiago, Chile

5
IVAN CALDERON

Associate Professor / Principal Investigator/ Master in Biotechnology & Life Sciences Director

Biological Sciences

UNIVERSIDAD ANDRÉS BELLO

SANTIAGO, Chile

4
Daniel Paredes

Associate Professor

Department of Biological Sciences

Universidad Andrés Bello

Santiago, Chile

4
Guido Mora

Académico/Investigador

Facultad Ciencias de la Salud

Universidad SEK

Santiago, Chile

3
Fernando Gil

Associate Professor

Biological Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

3
Claudio Acuña

Profesosr Asociado

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

2
Katherine Zepeda

alumno tesista

Quimica y Biologia

Universidad de Santiago de Chile

Santiago, Chile

2
Alejandro Escobar

assistant professor

Institute for Research in Dental Sciences

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Luis Constandil

Profesor Titular

Biología

Universidad de Santiago de Chile

Santiago, Chile

2
Rolando Vernal

Profesor Titular

Departamento de Odontología Conservadora

UNIVERSIDAD DE CHILE

Santiago, Chile

2
Cristian Vilos

Académico Jornada Completa

Medicina

Universidad de Talca

Talca, Chile

2
Rodrigo Iglesias

Tecnólogo médico

Biomédico

Instiuto de Salud Publica de Chile

Santiago, Chile

2
AURA VILLAMIL

Consultora Nacional en Resistencia Antimicrobiana

Resistencia antimicrobiana

Organización Panamericana de la Salud

Santiago, Chile

1
Paula Solar

Directora de Investigación y Posgrado

Dirección de Investigación y Posgrado

Universidad SEK

Santiago, Chile

1
NATALIA JUICA

Bioquímico

Facultad de Ciencias de la Salud

Universidad SEK

Santiago, Chile

1
SERGIO BUCAREY

Profesor Asociado

Departamento de Ciencias Biológicas Animales

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS VETERINARIAS Y PECUARIAS

Santiago, Chile

1
Maria Otero

Profesor Asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
LILLIAN ACUÑA

INVESTIGADOR POST-DOCTORAL FONDECYT

Laboratorio de Genética y Patógenesis Bacteriana

Universidad Andrés Bello

SANTIAGO, Chile

1
Paulina Calderón

Investigador Principal

Biome Therapeutics

Santiago, Chile

1
Caroll Beltrán

Profesor Asistente, Investigador Principal

Medicina

Universidad de Chile, Fac Medicina

SANTIAGO, Chile

1
Francisco Morales

Posdoctoral

Universidad de Chile. Centro FONDAP ACCDiS

Santiago, Chile

1
Fabien MAGNE

Profesor asistante

UNIVERSIDAD DE CHILE

Chile

1
Claudia Lefimil

Profesor Asistente

Instituto de Investigación en Ciencias odontológicas

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Hugo Salinas

Profesor asociado

Hospital Clínico U de Chile

Universidad de Chile

Santiago, Chile

1
Ricardo Ramires

Director Científico

Centro de Oncología de Precisión

Universidad Mayor de Chile

Santiago, Chile

1
Carmen Imarai

Profesor Titular

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Mercedes López

Profesora Asociada

Instituto de Ciencias Biomédicas

Universidad de chile

Santiago, Chile

1
Ítalo Urrutia

Profesor Asistente

Universidad Autónoma de Chile

Santiago, Chile

1
pamela araya

JEFE DE SECCIÓN

BIOMEDICO

INSTITUTO DE SALUD PUBLICA DE CHILE

SANTIAGO, Chile

1
Felipe Simon

Profesor Titular

Department of Biological Sciences

UNIVERSIDAD ANDRES BELLO FAC DE CS BIOLOGICAS, DPTO DE CS BIOLOGICAS

Santiago, Chile

1
Daniel Ibáñez

Profesional

Laboratorio Biomédico

Instituto de Salud Pública de Chile

Santiago, Chile

1
Pedro Orihuela

Profesor Asociado

Biología

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Katherine Garcia

PROFESOR ASOCIADO

UNIVERSIDAD AUTONOMA DE CHILE

Santiago, Chile

1
Juan Hormazabal

Jefe

Departamento Biomédico

Public Health Institute of Chile

Santiago, Chile

1
Annette Trombert

Directora de Escuela

Biotecnología

UNIVERSIDAD MAYOR, INSTITUTO DE BIOTECNOLOGÍA, CENTRO DE GENÓMICA Y BIOINFORMÁTICA

Santiago, Chile

1
Susan Bueno

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile