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Sebastian Gatica Fernández

Académico investigador

Universidad Santo Tomás

Santiago, Chile

Líneas de Investigación


Sepsis: Fisiopatología, Inmunología, Epidemiología, Data Science

Educación

  •  Biociencias Moleculares, UNIVERSIDAD ANDRES BELLO. Chile, 2020
  •  Tecnólogo Médico, UNIVERSIDAD DE CHILE. Chile, 2011

Experiencia Académica

  •   Investigador Asociado Full Time

    UNIVERSIDAD CATOLICA DE LA SANTISIMA CONCEPCION

    Chile

    2012 - 2013

  •   Investigador Postdoctoral Full Time

    UNIVERSIDAD ANDRES BELLO

    Chile

    2022 - 2025

  •   Académico investigador Full Time

    UNIVERSIDAD SANTO TOMAS

    Chile

    2025 - A la fecha

Experiencia Profesional

  •   Académico investigador Full Time

    Universidad Santo Tomás

    Chile

    2025 - A la fecha


 

Article (28)

Gestational Hypothyroxinemia Shifts Th1/Th17 Immunity and Innate Lymphoid Cell Balance in the Adult Offspring during the Presymptomatic Stage of Experimental Autoimmune Encephalomyelitis

Gatica, Sebastian; Paillal, Nicolas; Rangel-Ramirez, Ma. Andreina; Mendez, Luis; Fernandez-Tello, Alonso; Kalergis, Alexis M.; Bueno, Susan M.; Gonzalez, Pablo A.; Soto, Jorge A.; Simon, Felipe; et al.

Article ISI
NEUROIMMUNOMODULATION  (2025)

From genes to systems: The role of food supplementation in the regulation of sepsis-induced inflammation



Article ISI
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE  (2024)

Transient gestational hypothyroxinemia accelerates and enhances ulcerative colitis-like disorder in the male offspring

Hernandez-Armengol, Rosario; Bohmwald, Karen; Bueno, Susan M.

Article ISI
FRONTIERS IN ENDOCRINOLOGY  (2024)

Appraisal of the Neuroprotective Effect of Dexmedetomidine: A Meta-Analysis

Gatica, Sebastian; Aravena, Cristobal; Prado, Yolanda; Aravena, D.; ECHEVERRIA-LEAL, CRISTIAN MAURICIO; SANTIBANEZ-DOMINGUEZ, JUAN FRANCISCO; RIEDEL-SORIA, CLAUDIA ANDREA; STEHBERG-LIBERMAN, JIMMY RAN; SIMON-PINO, FELIPE ALONSO

Article SCOPUS
Advances in Experimental Medicine and Biology  (2023)

Disseminated intravascular coagulation phenotype is regulated by the TRPM7 channel during sepsis

Jimenez-Dinamarca, Ivanka; Alt, Clemens; Lin, Charles P.; Correa, Simon

Article ISI SCIELO
BIOLOGICAL RESEARCH  (2023)

Effects of Adrenergic Receptor Stimulation on Human Hemostasis: A Systematic Review

Gatica, Sebastian; Aravena, D.; ECHEVERRIA-LEAL, CRISTIAN MAURICIO; SANTIBANEZ-DOMINGUEZ, JUAN FRANCISCO; RIEDEL-SORIA, CLAUDIA ANDREA; SIMON-PINO, FELIPE ALONSO

Article SCOPUS
Advances in Experimental Medicine and Biology  (2023)

Is there a role for herpes simplex virus type 1 in multiple sclerosis?

Castillo, Almendra; Bueno, Susan M.

Article ISI
MICROBES AND INFECTION  (2023)

Novel evidence on sepsis-inducing pathogens: from laboratory to bedside

Fuentes, Brandon; Rivera-Asin, Elizabeth; Ramirez-Cespedes, Paula; Bueno, Susan M.

Article ISI
FRONTIERS IN MICROBIOLOGY  (2023)

Small Plastics, Big Inflammatory Problems

Prado, Yolanda; Aravena, Cristobal; Aravena, D.; Eltit, Felipe; Gatica, Sebastian; RIEDEL-SORIA, CLAUDIA ANDREA; SIMON-PINO, FELIPE ALONSO

Article SCOPUS
Advances in Experimental Medicine and Biology  (2023)

Statins and Hemostasis: Therapeutic Potential Based on Clinical Evidence

Prado, Yolanda; Aravena, D.; Marchant, Felipe; Aravena, Cristobal; Eltit, Felipe; ECHEVERRIA-LEAL, CRISTIAN MAURICIO; Gatica, Sebastian; RIEDEL-SORIA, CLAUDIA ANDREA; SIMON-PINO, FELIPE ALONSO

Article SCOPUS
Advances in Experimental Medicine and Biology  (2023)

α1-Adrenergic Stimulation Increases Platelet Adhesion to Endothelial Cells Mediated by TRPC6

Marchant, Felipe; Vallejos, Alejando; Aravena, D.; Prado, Yolanda; Gatica, Sebastian; Otero, Carolina; SIMON-PINO, FELIPE ALONSO

Article SCOPUS
Advances in Experimental Medicine and Biology  (2023)

Endothelial dysfunction in pregnancy metabolic disorders



Article ISI
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE  (2020)

TRPM7 mediates kidney injury, endothelial hyperpermeability and mortality during endotoxemia

Aballai V.

Article ISI SCOPUS
LABORATORY INVESTIGATION  (2020)

Circulating Endothelial Cells From Septic Shock Patients Convert to Fibroblasts Are Associated With the Resuscitation Fluid Dose and Are Biomarkers for Survival Prediction

Cortés-Rivera, Cristian; Otero, Carolina; Becerra, Alvaro; Riedel, Claudia A.; Kalergis, Alexis M.; Simon, Felipe

Article ISI SCOPUS
CRITICAL CARE MEDICINE  (2019)

Endothelial Cells Exhibit Two Waves of P-selectin Surface Aggregation Under Endotoxic and Oxidative Conditions

Barrionuevo N.

Article ISI SCOPUS
PROTEIN JOURNAL  (2019)

Endothelial dysfunction in pregnancy metabolic disorders

Echeverria C, Eltit F; Santibanez J, Gatica S; Cabello-Verrugio C, Simon F

Article
Biochim Biophys Acta Mol Basis Dis  (2019)

Endotoxemia-induced endothelial fibrosis inhibition improves hypotension, tachycardia, multiple organ dysfunction syndrome, cytokine response, oxidative stress, and survival

Vallejos A.

Article ISI SCOPUS
LABORATORY INVESTIGATION  (2019)

Expression Suppression and Activity Inhibition of TRPM7 Regulate Cytokine Production and Multiple Organ Dysfunction Syndrome During Endotoxemia: A New Target for Sepsis



Article ISI SCOPUS
CURRENT MOLECULAR MEDICINE  (2019)

Transient Receptor Potential Vanilloid 1 Expression Mediates Capsaicin-Induced Cell Death

Cordova,Claudio; Rodriguez, Belen; Lozano, Carlo; Marchant, Ivanny; Simon, Felipe; Olivero, Pablo

Article ISI SCOPUS
FRONTIERS IN PHYSIOLOGY  (2018)

Transient Receptor Potential Vanilloid 1 Expression Mediates Capsaicin-Induced Cell Death

Ramírez-Barrantes R, Córdova C; Gatica S, Rodriguez B; Lozano C, Marchant I; Simon F, Olivero P

Article
Frontiers in Physiology  (2018)

Human Peritoneal Mesothelial Cell Death Induced by High-Glucose Hypertonic Solution Involves Ca2+ and Na+ Ions and Oxidative Stress with the Participation of PKC/NOX2 and PI3K/Akt Pathways

Gatica, Sebastian; Sanhueza, Maria E.; Segovia, Erico

Article ISI SCOPUS
FRONTIERS IN PHYSIOLOGY  (2017)

Abortion legislation, maternal healthcare, fertility, female literacy, sanitation, violence against women and maternal deaths: a natural experiment in 32 Mexican states

Koch E.; Chireau, M; Pliego, F; Stanford, J; Haddad, S; Calhoun, B; Aracena P.; Bravo M.; Gatica S; Thorp, J

Article ISI SCOPUS
BMJ Open  (2015)

Women's education level, contraceptive use and maternal mortality estimates

Koch E.; Calhoun, B; Aracena P.; Gatica S; Bravo M.

Article ISI SCOPUS
PUBLIC HEALTH  (2014)

Determination of the differential expression of mitochondrial long non-coding RNAs as a noninvasive diagnosis of bladder cancer

Rivas, A; Burzio V; Landerer, E.; Borgna, V; Gatica S; Avila, R.; Lopez, C; Villota, C; De la Fuente, R.; Echeñique J.; et al.

Article ISI SCOPUS
BMC Urology  (2012)

Fundamental discrepancies in abortion estimates and abortion-related mortality: A reevaluation of recent studies in Mexico with special reference to the International Classification of Diseases

Koch E.; Aracena P.; Gatica S; Bravo M.; Huerta-Zepeda A.; Calhoun B.C.

Article SCOPUS
International Journal of Women's Health  (2012)

Overcoming barriers in the management of hypertension: The experience of the cardiovascular health program in chilean primary health care centers

Sandoval, D; Bravo M.; Koch E.; Gatica S; Ahlers I.; Henriquez O.; Romero T,

Article SCOPUS
International Journal of Hypertension  (2012)

Overestimation of abortion in Colombia and other Latin American countries [Sobrestimación del aborto inducido en Colombia y otros países latinoamericanos]

Koch E.; Bravo M.; Gatica S; Stecher J.F.; Aracena P.; Valenzuela S.; Ahlers I.

Article SCOPUS
Ginecologia y Obstetricia de Mexico  (2012)

Women's Education Level, Maternal Health Facilities, Abortion Legislation and Maternal Deaths: A Natural Experiment in Chile from 1957 to 2007

Koch E.; Thorp, J; Bravo M.; Gatica S; Aguilera, H; Ahlers I.

Article ISI SCOPUS
PLOS ONE  (2012)

Abstract (2)

A single FISH procedure for the detection of tumor cells: Bladder cancer as model

Rivas, A; Landerer, E.; Burzio V; Gatica S; Lopez, C; Villegas, J

Abstract ISI
EJC SUPPLEMENTS  (2010)

Waist-to-Height Ratio as a Simple and Useful Measure to Define Visceral Adiposity and Metabolic Syndrome Risk: A Cross-Sectional Study in Chilean Women

Koch E.; Gatica S; Romero T,; Romero C.; Manriquez, L; Ahumada C.; Diaz, C.; Henriquez O.; Segovia, I; Nivelo, M

Abstract ISI
CIRCULATION  (2010)

Letter (1)

Deficiencies in the estimation of abortions in Latin America: Reply authors Singh and Bankole [Deficiencias en la estimación de abortos para Latinoamérica: Respuesta de los autores a Singh y Bankole]

Koch E.; Bravo M.; Gatica S; Stecher J.F.; Valenzuela S.; Ahlers I.

Letter SCOPUS
Ginecologia y Obstetricia de Mexico  (2012)

Proyecto (4)

PARTICIPATION OF TRPM7 IN THE GENERATION OF ENDOTHELIAL DYSFUNCTION CHARACTERISTICS, ENHANCED INFLAMMATORY RESPONSE, AND MULTIPLE ORGAN FAILURE DURING ENDOTOXEMIA

FONDEF (1161288)

Proyecto
2016-2020
Tesista

Postergación de la maternidad de la mujer chilena y su impacto sobre el perfil de causas de mortalidad materna=> estudio de series de tiempo paralelas entre 1960 y 2010

FONIS (SA13I10430)

Proyecto
2015-2016
Coinvestigador(a)

Which are the main factors related to maternal and abortion mortality reduction in Chile? Time series analyses from 1957 to 2007

UNC Research Foundation, Chapel Hill, NC (UNC102010)

Proyecto
2010-2012
Coinvestigador(a)

DESARROLLO DE UN SISTEMA DE ALTA EFICIENCIA PARA LA IDENTIFICACION DE CELULAS NEOPLASICAS EN PACIENTES PORTADORES DE UN CANCER VESICAL, BASADO EN LA EXPRESION DIFERENCIAL DE UNA NOVEDOSA FAMILIA DE RNAS MITOCONDRIALES

FONDECYT (1085210)

Proyecto
2008-2011
Tesista

Review (1)

Transforming growth factor-beta family: Advances in vascular function and signaling



Review ISI SCOPUS
 (2018)

11
Felipe Simon

Profesor Titular

Department of Biological Sciences

UNIVERSIDAD ANDRES BELLO FAC DE CS BIOLOGICAS, DPTO DE CS BIOLOGICAS

Santiago, Chile

2
Verónica Burzio

Investigadora Asociada

Fundacion Ciencia y Vida

Santiago, Chile

1
Claudio Villota

Profesor/investigador Asociado

Facultad de Salud

Universidad Bernardo O'Higgins

Santiago, Chile

1
Alexis Kalergis

Full Professor

Microbiología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE. FACULTAD DE CIENCIAS BIOLÓGICAS

Santiago, Chile

3
Susan Bueno

Profesor Asociado

Genética Molecular y Microbiología

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

1
Ricardo Armisen

Associate Professor

Centro de Genética y Genómica

Universidad del Desarrollo

Santiago, Chile

2
Luis Burzio

Scientific Director

Andes Biotechnologies

FUNDACION CIENCIA PARA LA VIDA

Santiago, Chile

2
Jaime Villegas

Profesor Asociado

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

2
Alexis Rivas

Investigador Postdoctoral

Instituto de Neurociencias Biomédicas

Universidad de Chile

Santiago, Chile

1
Ivanny Marchant

Directora Unidad de Estudios Clínicos

ESCUELA DE MEDICINA UNIVERSIDAD DE VALPARAISO

Valparaiso, Chile

1
Eduardo Landerer

ENCARGADO POSTGRADO UROLOGÍA HFB

UROLOGÍA

UNIVERSIDAD DE SANTIAGO DE CHILE

Santiago, Chile

1
Diego Varela

Profesor Asociado

Fisiología y Biofísica

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

1
Maria Opazo

Profesor Asociado

Universidad de Las Américas

Santiago, Chile

7
Claudio Cabello

Full Professor

Ciencias Biologicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Carmen Feijóo

Profesor asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

5
César Echeverría

DIRECTOR DE INVESTIGACIÓN

Medicina

Universidad de Atacama

COPIAPO, Chile

3
Claudia Riedel

Full Professor

Life Sciences

Universidad Andres Bello

Santiago, Chile

2
Pablo Tapia

Jefe Técnico Unidad de Paciente Crítico (UPC)

Unidad Paciente Critico (UPC)

Hospital Clinico Metropolitano La Florida

Santiago, Chile

1
Maria Otero

Profesor Asociado

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Juan Santibáñez

Professor of Research

Molecular Oncology

Institute for Medical Research

Belgrade, Serbia

1
Karen Bohmwald

Académico Investigador

Universidad Autónoma de Chile

Santiago, Chile

2
jaime villegas

Investigador Senior

Andes Biotechnologies

Fundación Ciencia para la Vida

Santiago, Chile

1
Laura Ahlers

Académico Profesor Asociado

Atención Primaria y Salud Familiar

Universidad de Chile

Santiago, Chile

1
Hernán Aguilera

Académico/ Directivo

Universidad de Chile

Santiago, Chile

1
DANIELA SANDOVAL

Profesor Asistente

Departamento de Atención Primaria y Salud Familiar

Universidad de Chile

Santiago, Chile

2
Oscar Henriquez

Profesor Asistente

Departamento de Atención Primaria y Salud Familiar

Universidad de Chile

Santiago, Chile

1
Tomás Romero

1
Belen Rodriguez

Jefa de Calidad

Departamento de Patología

Universidad de Valparaíso

Viña del Mar, Chile

1
Claudio Cordova

Investigador asistente

Medicina

Universidad de Valparaíso

Valparaíso, Chile

1
FELIPE MELO

Profesor Asistente

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

1
Ricardo Ramírez

Coordinador académico

Universidad Andrés Bello

Viña del Mar, Chile

1
carlo lozano

Profesor asociado

Facultad de Medicina

Universidad de Valparaíso

Valparaíso, Chile

1
Alejandro Vallejos

Asistente de Investigación

Ciencias de la Vida

Laboratorio de Fisiopatología Integrativa

Santiago, Chile

1
Alvaro Becerra

Profesor Asociado

Ciencias Químico y Biológicas

Universidad Bernardo O'Higgins

Santiago, Chile

1
Maria Mendoza

PhD. Candidat

Ciencias de la Vida

Universidad Andrés Bello

Santiago, Chile

1
LUISA DUARTE

Assistant Researcher Professor

Instituto de Ciencias e innovación en Medicina, Facultad de Medicina

Universidad del Desarrollo

Santiago, Chile

1
Eduardo Catalán

Lab Manager

Ciencias Biológicas

Universidad Andrés Bello

Santiago, Chile

30
Sebastian Gatica

Académico investigador

Universidad Santo Tomás

Santiago, Chile

1
simon correa

Head of Computational Biology

Computational Biology

Protera

Santiago, Chile

1
Cristian Cortés

Académico-Investigador Auxiliar

Psicología

Universidad Católica del Maule

Talca, Chile