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Isabel Cornejo Araneda

Investigadora

Centro de Estudios Científicos

Valdivia, Chile

Biología celular y molecular de canales iónicos acoplado al desarrollo de modelos murinos modificados genéticamente que permitan el estudio fisiopatológico de canales.

Biología Celular y Molecular, UNIVERSIDAD AUSTRAL DE CHILE. Chile, 2007
Tecnólogo Médico, UNIVERSIDAD DE TALCA. Chile, 1998
Lab Clínico y Banco de Sangre, UNIVERSIDAD DE TALCA. Chile, 2000

Investigadora Full Time

Universidad San Sebastián

Valdivia, Chile

2022 - A la fecha


Altered phosphatidylinositol regulation of mutant inwardly rectifying K+ Kir7.1 channels associated with inherited retinal degeneration disease Vera, Erwin; Cornejo, Isabel; Isabel Niemeyer, Maria; Sepulveda, Francisco, V; Pablo Cid, L. Article ISI JOURNAL OF PHYSIOLOGY-LONDON (2021)
A novel Kir7.1 splice variant expressed in various mouse tissues shares organisational and functional properties with human Leber amaurosis-causing mutations of this K+ channel Vera E.; Cornejo I.; Burgos J.; Niemeyer M.I.; SepÃºlveda F.V.; Cid L.P. Article ISI SCOPUS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
Kir7.1 inwardly rectifying K+ channel is expressed in ciliary body non pigment epithelial cells and might contribute to intraocular pressure regulation Burgos J.; Villanueva S.; Ojeda M.; Cornejo I.; Cid L.P.; SepÃºlveda F.V. Article ISI SCOPUS EXPERIMENTAL EYE RESEARCH (2019)
Tissue Distribution of Kir7.1 Inwardly Rectifying K+ Channel Probed in a Knock-in Mouse Expressing a Haemagglutinin-Tagged Protein Cornejo, I; Villanueva, S; Burgos, J; Lopez-Cayuqueo, KI; Chambrey, R; Julio-Kalajzic, F; Buelvas, N; Niemeyer, MI; Figueiras-Fierro, D; Brown, PD; Sepulveda, FV; Cid, LP Article ISI SCOPUS FRONTIERS IN PHYSIOLOGY (2018)
Identification and Functional Expression of a Glutamate and Avermectin-Gated Chloride Channel from Caligus rogercresseyi, a Southern Hemisphere Sea Louse Affecting Farmed Fish Cornejo I, Andrini O, Niemeyer MI, Marabolí V, González-Nilo FD, Teulon J, Sepúlveda FV, Cid LP Article ISI SCOPUS PLOS PATHOGENS (2014)
Isolation of the Atlantic salmon beta-actin promoter and its use to drive expression in salmon cells in culture and in transgenic zebrafish Cornejo I.; Sepulveda, FV; Kibenge FSB; Young, JI Article ISI SCOPUS Aquaculture (2010)
Rapid Recycling of ClC-2 Chloride Channels Between Plasma Membrane and Endosomes: Role of a Tyrosine Endocytosis Motif in Surface Retrieval Cornejo I.; Niemeyer, MI; Zuniga, L.; Yusef, YR; Sepulveda, FV; Cid, LP Article ISI SCOPUS JOURNAL OF CELLULAR PHYSIOLOGY (2009)
A genetically encoded ratiometric sensor to measure extracellular pH in microdomains bounded by basolateral membranes of epithelial cells Urra, J; Sandoval M.; Cornejo I.; Barros, LF; Sepulveda, FV; Cid, LP Article ISI SCOPUS PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2008)
Basolateral localization of native ClC-2 chloride channels in absorptive intestinal epithelial cells and basolateral sorting encoded by a CBS-2 domain di-leucine motif Pena-Muzenmayer, G; Catalán M.; Cornejo I.; Figueroa, CD; Melvin, JE; Niemeyer, MI; Cid, LP; Sepulveda, FV Article ISI SCOPUS JOURNAL OF CELL SCIENCE (2005)
Functional evaluation of human ClC-2 chloride channel mutations associated with idiopathic generalized epilepsies Niemeyer M.I.; Yusef Y.R.; Cornejo I.; Flores C.A.; Sepulveda, F. V.; Cid, L. P. Article SCOPUS Physiological Genomics (2005)
ClC-2 in guinea pig colon: mRNA, immunolabeling, and functional evidence for surface epithelium localization Catalán M.; Cornejo I.; Figueroa, CD; Niemeyer, MI; Sepulveda, FV; Cid, LP Article ISI SCOPUS AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2002)
Cloning, cellular distribution and functional expression of small intestinal epithelium guinea pig C1C-5 chloride channel Cornejo, I; Niemeyer, MI; Sepulveda, FV; Cid, LP Article ISI BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2001)


Study of human pathological mutations in Kir 7.1 potassium channels at cellular and systemic level. Luis Pablo Cid Proyecto (2019)
CHARACTERIZATION OF THE ROLE OF KIR 7.1 POTASSIUM CHANNELS IN RENAL ELECTROLYTE TRANSPORT USING A GENETIC APPROACH. FONDECYT (1150735) Proyecto 2015-2019 Coinvestigador(a)
Traffic and expression of ClC-2 chloride channel in the cell surface. DID-Uach (D-2004-05) Proyecto 2004-2005 Inv. Responsable

13

Isabel Cornejo

Investigadora

Biología

Centro de Estudios Científicos

Valdivia, Chile

6

Luis Cid

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTIFICOS CECs

Valdivia, Chile

5

Francisco Sepúlveda

Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS (CECS)

Valdivia, Chile

4

Maria Niemeyer

Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTIFICOS CECS

Valdivia, Chile

3

Carlos Figueroa

Head

Anatomy, Histology and Pathology

Universidad Austral de Chile

Valdivia, Chile

3

Johanna Burgos

Postdoctoral

Biología

Centro de Estudios Científicos

Valdivia, Chile

2

Sandra Villanueva

Tesista

Biología

Centro de Estudios Científicos

Valdivia, Chile

2

Marcelo Catalan

Profesor Auxiliar

Facultad de Medicina

Universidad Austral de Chile

Valdivia, Chile

1

Luis Barros

Principal Research

Laboratorio Biología Molecular

CENTRO DE ESTUDIOS CIENTÍFICOS

Valdivia, Chile

1

Dulce Figueiras

Investigador responsable

Medicina

Universidad de La Frontera

Temuco, Chile

1

Moisés Sandoval

Co-Investigador

Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

1

Neudo Buelvas

Asistente de Investigación

Biología

Centro de Estudios Científicos

Valdivia, Chile

1

Fernando Gonzalez

Titular Professor

Facultad de Ciencias de la Vida

Universidad Andres Bello

Santiago, Chile

1

VANESSA MARABOLI

Gestora de Proyectos

Vicerrectoría de Investigación y Doctorado

Universidad Andrés Bello

Santiago, Chile

1

Leandro Zuñiga

Profesor Asociado

Medicine

Universidad de Talca

Talca, Chile

1

Gaspar Peña

Profesor Asistente

Instituto de Bioquímica y Microbiología

Universidad Austral de Chile

Valdivia, Chile

1

Carlos Flores

Researcher

Biology Lab

CENTRO DE ESTUDIOS CIENTÍFICOS (CECS)

Valdivia, Chile