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Daniel Alonso González Mañán

Académico regular

Universidad Mayor de Chile

Santiago, Chile

Líneas de Investigación


Enfermedad por hígado graso no alcohólico; Síndrome metabólico; Compuestos bioactivos.

Educación

  •  Doctor en Nutrición y Alimentos, UNIVERSIDAD DE CHILE. Chile, 2017
  •  Bioquímico, UNIVERSIDAD DE CHILE. Chile, 2012
  •  Licenciado en Bioquímica, UNIVERSIDAD DE CHILE. Chile, 2010

Experiencia Académica

  •   Profesor asociado Full Time

    Universidad Mayor

    Facultad de Ciencias, Ingeniería y Tecnología

    SANTIAGO, Chile

    2018 - A la fecha

  •   Profesor ayudante Part Time

    Universidad de O'Higgins

    Rancagua, Chile

    2017 - 2017


 

Article (17)

Dietary alpha- and gamma-tocopherol (1:5 ratio) supplementation attenuates adipose tissue expansion, hepatic steatosis, and expression of inflammatory markers in a high-fat-diet-fed murine model
Iron-induced derangement in hepatic ?-5 and ?-6 desaturation capacity and fatty acid profile leading to steatosis: Impact on extrahepatic tissues and prevention by antioxidant-rich extra virgin olive oil
Reduction of high-fat diet-induced liver proinflammatory state by eicosapentaenoic acid plus hydroxytyrosol supplementation=> involvement of resolvins RvE1/2 and RvD1/2.
Anti-oxidative and anti-inflammatory effects of Rosa Mosqueta oil supplementation in rat liver ischemia-reperfusion.
Molecular mechanisms related to the hepatoprotective effects of antioxidant-rich extra virgin olive oil supplementation in rats subjected to short-term iron administration
Role of dietary α- and γ-tocopherol from Rosa mosqueta oil in the prevention of alterations induced by high-fat diet in a murine model.
Effects of rosa mosqueta oil supplementation in lipogenic markers associated with prevention of liver steatosis
Rosa mosqueta oil prevents oxidative stress and inflammation through the upregulation of PPAR-? and NRF2 in C57BL/6J mice fed a high-fat diet
Supplementation with Docosahexaenoic Acid and Extra Virgin Olive Oil Prevents Liver Steatosis Induced by a High-Fat Diet in Mice through PPAR-? and Nrf2 Upregulation with Concomitant SREBP-1c and NF-kB Downregulation
Increase in endogenous estradiol in the progeny of obese rats is associated with precocious puberty and altered follicular development in adulthood
n-3 LCPUFA in the reversal of hepatic steatosis=> the role of ACOX and CAT-1
Dietary Rosa mosqueta (Rosa rubiginosa) oil prevents high diet-induced hepatic steatosis in mice
N-3 long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation in relation to PPAR-alpha upregulation and NF-kappa B DNA binding abrogation
Prevention of liver steatosis through fish oil supplementation=> correlation of oxidative stress with insulin resistance and liver fatty acid content
Bioconversion of alpha-linolenic acid to n-3 LCPUFA and expression of PPAR-alpha, acyl coenzyme A oxidase 1 and carnitine acyl transferase I are incremented after feeding rats with alpha-linolenic acid-rich oils
N-3 Long-Chain Polyunsaturated Fatty Acid Supplementation Significantly Reduces Liver Oxidative Stress in High Fat Induced Steatosis
Nuevas fuentes dietarias de acido alfa-linolénico=> una visión crítica

Proyecto (3)

"Hepatoprotective mechanisms of Rosa rubiginosa oil (Rosa mosqueta) in preconditioning against ischemia reperfusion injury in healthy and steatotic liver and prevention of liver steatosis=> role of Nrf2, PPAR-alpha, NF-kB and expression of
Promoción del uso de aceite de rosa mosqueta para el tratamiento de la resistencia a la insulina y esteatosis
“Protection with oral n-3 PUFA (EPA + DHA) supplementation against liver injury, inflammation, oxidative stress and insuline resistance induced by a high-fat diet=> activation of PPAR-alpha and NF-kB inactivation”
2
Daniel González

Académico regular

Núcleo de química y bioquímica

Universidad Mayor de Chile

Santiago, Chile

1
Berta Espinosa

Full Professor

Tecnología Médica

Universidad de Chile

Santiago, Chile

1
Amanda D'Espessailles

Investigadora Postdoctoral

Instituto de Ciencias de a Salud

Universidad de O'Higgins

Rancagua, Chile

1
Gladys Tapia

Academica

Farmacología Molecular y Clínica

FACULTAD DE MEDICINA UNIVERSIDAD DE CHILE

Santiago, Chile

1
SANDRA LOPEZ

Profesora Asistente

Nutrición

Universidad de Chile

Santiago, Chile

1
Nalda Romero

Profesora Asociada

Ciencia de los Alimentos

UNIVERSIDAD DE CHILE

Santiago, Chile

1
Miguel Ángel Rincón

Académico profesor asociado

INSTITUTO DE NUTRICION Y TECNOLOGIA DE LOS ALIMENTOS

Santiago, Chile