Man

Carlos Felipe Henríquez Olguín

Professor Asistente

Universidad Finis Terrae

Santiago, Chile

Líneas de Investigación


Molecular Metabolism in Metabolic Diseases Muscle Cell Biology Cellular Mechanisms in Health-Promoting Effects of Exercise

Educación

  •  Fisiología , UNIVERSIDAD DE CHILE. Chile, 2013
  •  Ciencias Biomedicas, UNIVERSIDAD DE CHILE. Chile, 2018
  •  Tecnólogo en deportes y recreación, UNIVERSIDAD DE PLAYA ANCHA DE CIENCIAS DE LA EDUCACION. Chile, 2008
  •  Molecular Physiology , University of Copenhagen . Dinamarca, 2018

Experiencia Académica

  •   Profesor Part Time

    UNIVERSIDAD ANDRES BELLO

    Facultad de Ciencias

    Viña del Mar, Chile

    2011 - 2014

  •   Profesor Invitado Part Time

    UNIVERSIDAD DE CHILE

    Facultad de Medicina

    Santiago , Chile

    2015 - A la fecha

  •   Assistant Professor Full Time

    UNIVERSITY OF COPENHAGEN

    Faculty of Science

    Copenhagen, Dinamarca

    2023 - 2024

  •   Visiting Research Fellow Full Time

    HARVARD UNIVERSITY

    Harvard Medical School (HMS)

    Estados Unidos

    2023 - 2024

  •   Profesor Asistente Full Time

    UNIVERSIDAD FINIS TERRAE

    Medicina

    Santiago , Chile

    2024 - A la fecha

Experiencia Profesional

  •   Encargado provincial escuelas EGO Full Time

    Ministerio de Salud

    Valparaíso, Chile

    2009 - 2010

  •   Fisiólogo del Ejercicio Part Time

    Instituto Nacional de Deportes

    Valparaíso, Chile

    2008 - A la fecha

  •   Fisiólogo del Ejercicio Part Time

    Clinica MEDS

    Santiago , Chile

    2011 - 2015

Formación de Capital Humano


2023: Main Lab Supervisor and Co-tutor, 1 MSc Student University of Copenhagen (UCPH).
2023: Main Lab Supervisor Guest PhD Student (Spain).
2022- date: Main Lab Supervisor and Co-tutor, 2 PhD Students (UCPH).
2021: Main Lab Supervisor and Co-tutor, 1 MSc Student (UCPH) and 1 Intern (Greece).
2020: Main Lab Supervisor and Co-tutor, 1 MSc Student (UCPH), and 1 Summer Intern (Italy).
2019: Main Lab Supervisor, 2 BSc Students (UCPH) and 2 Summer Interns (India and France).
2018: Main Lab Supervisor, 2 Guest Ph.D. Students (Iran and Chile).
2014: Main MSc Thesis Supervisor, 2 MSc (in Sports Nutrition) Students, Mayor University, Chile.


Difusión y Transferencia


- 2013: Talk at Explorada Activity at the Faculty of Medicine, University of Chile. Skeletal Muscle in Sport and Health.
- 2022: Participation in Podcast Neurobiologia del Movimiento.
- 2024: Participation in Podcast "Inside Exercise" with Dr. Glenn McConell, University of Melbourne.


Premios y Distinciones

  •   Best Oral Presentation Award

    Centre of Healthy Aging, University of Copenhagen

    Dinamarca, 2017

    Best scientific work in oral presentation modality. Mitochondrial summer School

  •   Premio al Egresado Destacado

    UNIVERSIDAD DE PLAYA ANCHA DE CIENCIAS DE LA EDUCACION

    Chile, 2016

    Premio a la excelencia para egresados destacados

  •   ASBMB 2015 Gradute/Postdoctoral Travel Award

    Entidad emisora del reconocimientoAmerican Society for Biochemistry and Molecular Biology.

    Estados Unidos, 2015

    Beca de viaje para asistir a conferencia experimental biology.

  •   ECSS Young Investigator Award (YIA)

    European College Sports Science

    Holanda, 2014

    5th Winner, Young Investigator Award (YIA) in oral presentation category: ""NOX2-dependent ROS production modulates intracellular signaling induced by acute endurance exercise”. ECSS Meeting, Amsterdam.

  •   13th IBEC Young Investigator Award

    International Research Group on Exercise Biochemistry

    Canada, 2022

    Undeniably among the world's most prestigious awards for early-career researchers in exercise biochemistry, conferred triennially to outstanding achievers in the field

  •   Catherine Pasquier Memorial Award

    The Society for Free Radical Research Europe

    Bélgica, 2022

    The distinguished award is granted yearly to one exceptional European researcher, acknowledging their remarkable scientific contributions while highlighting their potential for continued success and impact in the field

  •   The Future of Redox Biology Award,

    The International Society for Free Radical Research

    Italia, 2022

    Young Investigator Award in Recognition of extraordinary scientific achievements

  •   Best Ph.D. Thesis in Natural Sciences

    ACADEMIA CHILENA DE CIENCIAS

    Chile, 2022

    This award is given to the best Ph.D. thesis in natural sciences among all Ph.D. students in Chile.

  •   TOP 12 SCIENCE PhD Prize

    University of Copenhagen

    Dinamarca, 2019

    Thesis named among the Top-12 Ph.D. thesis among all projects at SCIENCE faculty (?300 Ph.D. students).


 

Article (41)

Adenosine monophosphate-activated protein kinase is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
From workout to molecular switches: How does skeletal muscle produce, sense, and transduce subcellular redox signals?
Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle
NOX2 deficiency exacerbates diet-induced obesity and impairs molecular training adaptations in skeletal muscle
The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action
AXIN1 knockout does not alter AMPK/mTORC1 regulation and glucose metabolism in mouse skeletal muscle
c-Myc overexpression increases ribosome biogenesis and protein synthesis independent of mTORC1 activation in mouse skeletal muscle
RNA-bound PGC-1α controls gene expression in liquid-like nuclear condensates
Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion
Contraction-regulated mTORC1 and protein synthesis: Influence of AMPK and glycogen
Housing temperature influences exercise training adaptations in mice
Prior exercise in humans redistributes intramuscular GLUT4 and enhances insulin -stimulated sarcolemmal and endosomal GLUT4 translocation
The ULK1/2 and AMPK Inhibitor SBI-0206965 Blocks AICAR and Insulin-Stimulated Glucose Transport
Adaptations to high-intensity interval training in skeletal muscle require NADPH oxidase 2
Chemical denervation using botulinum toxin increases Akt expression and reduces submaximal insulin-stimulated glucose transport in mouse muscle
Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise
Electroporated GLUT4-7<i>myc</i>-GFP detects <i>in vivo</i> glucose transporter 4 translocation in skeletal muscle without discernible changes in GFP patterns
Mechanisms involved in follistatin-induced hypertrophy and increased insulin action in skeletal muscle
Parkin the progression of sarcopenia
The Gut Microbiome on a Periodized Low-Protein Diet Is Associated With Improved Metabolic Health
beta-Actin shows limited mobility and is required only for supraphysiological insulin-stimulated glucose transport in young adult soleus muscle
Effects of Polarized Training on Cardiometabolic Risk Factors in Young Overweight and Obese Women: A Randomized-Controlled Trial
Lactate administration activates the ERK1/2, mTORC1, and AMPK pathways differentially according to skeletal muscle type in mouse
Periodized low protein-high carbohydrate diet confers potent, but transient, metabolic improvements
Effects of Exercise Training under Hyperbaric Oxygen on Oxidative Stress Markers and Endurance Performance in Young Soccer Players=> A Pilot Study
NOX2 Inhibition Impairs Early Muscle Gene Expression Induced by a Single Exercise Bout
NOX2 inhibition impairs early muscle gene expression induced by a single exercise bout
Reactive oxygen species and calcium signals in skeletal muscle=> a crosstalk involved in both normal signaling and disease
Whole Body Periodic Acceleration Improves Muscle Recovery after Eccentric Exercise
Whole Body Periodic Acceleration Improves Muscle Recovery after Eccentric Exercise.
Altered ROS production, NF-kappa B activation and interleukin-6 gene expression induced by electrical stimulation in dystrophic mdx skeletal muscle cells
Altered ROS production, NF-kB activation and Interleukin 6 gene expression induced by membrane depolarization in dystrophic mdx skeletal muscle cells.
Effects of plyometric training on endurance and explosive-strength performance in competitive middle and long distance runners.
Eight weeks of combined high intensity intermittent exercise normalized altered metabolic parameters in women.
Autonomic control of heart rate after exercise in trained wrestlers.
Somatotype Profile of Professional Male Soccer Chilean Players.
Metabolic response to high intensity exercise training in sedentary hyperglycemic and hypercholesterolemic women.
Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice.
Regional Fat Changes Induced By Localized Muscle Endurance Resistance Training.
Increased Resting Intracellular Calcium Modulates NF-kappa B-dependent Inducible Nitric-oxide Synthase Gene Expression in Dystrophic mdx Skeletal Myotubes
Mortality associated to physical inactivity in Santiago of Chile.

Abstract (2)

NF-kB-dependent IL-6 expression, induced by electrical stimulation, is reduced in dystrophic mdx skeletal muscle cells.
Increased Resting Calcium Modulates NF-kappa B Activity and iNOS Expression in mdx Myotubes

BookSection (2)

Exercise-Regulated Skeletal Muscle Glucose Uptake.
Entrenamiento físico, exceso de peso y obesidad.

Proyecto (3)

Señalización por estrés metabólico en cancer, enfermedades cardiovasculares y diabetes.
A NEW ROLE FOR DYSTROPHIN IN EXCITATION-TRANSCRIPTION COUPLING IN SKELETAL MUSCLE
FONDAP=> Centro de Estudios Moleculares de la Célula.

Review (3)

Compartmentalized muscle redox signals controlling exercise metabolism – Current state, future challenges
The Emerging Roles of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 in Skeletal Muscle Redox Signaling and Metabolism
Reactive oxygen species and calcium signals in skeletal muscle: A crosstalk involved in both normal signaling and disease
35
Carlos Henríquez

Professor Asistente

Kinesiologia

Universidad Finis Terrae

Santiago, Chile

8
Enrique Jaimovich

Full Professor

ICBM

FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

Santiago, Chile

2
Denisse Valladares

Assistant Professor

Universidad de O'Higgins

Rancagua, Chile

1
Cristian Campos

Entrenamiento Post Doctorado

Fisiología

Universidad de Chile

Santiago, Chile

1
igor cigarroa

Académico asociado

Facultad de Salud

Universidad Santo Tomás

Los Angeles, Chile

1
Paola Llanos

Profesor Asistente

Instituto de Investigacion en Ciencias Biomédicas

FACULTAD DE ODONTOLOGIA. UNIVERSIDAD DE CHILE

Santiago, Chile

1
RAFAEL ZAPATA

Académico

Didáctica Curriculum y Evaluación

UNIVERSIDAD DE CONCEPCIÓN

Los Angeles, Chile

1
YILDY UTRERAS

Postdoctoral researcher

Universidad de Los Andes

santiago, Chile

1
Claudio Cabello

Full Professor

Ciencias Biologicas

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Eduardo Fuentes

Profesor Asistente

Química Física

Pontificia Universidad Católica de Chile

Santiago, Chile