Nicolas Andres Tobar Bachler
Assistan Professor
Institute of nutrition and food technology
Santiago, Chile
Our main line of research is to determine which are the molecular mechanisms that allow us to link the inflammatory states derived from the intake of hypercaloric diets and the acquisition of tumor malignancy.
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Exact and Natural Sciences , UNIVERSIDAD DE CHILE. Chile, 1999
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Food and Nutrition, UNIVERSIDAD DE CHILE. Chile, 2015
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Molecular Biotechnology, UNIVERSIDAD DE CHILE. Chile, 2006
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Engineer in Molecular Biotechnology, UNIVERSIDAD DE CHILE. Chile, 2008
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Technological innovation, UNIVERSIDAD DE TALCA. Chile, 2007
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Postdoctoral researcher Full Time
UNIVERSIDAD DE CHILE
INTA
Santiago, Chile
2015 - 2018
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Laboratory Teacher Part Time
UNIVERSIDAD DE CHILE
INTA
Santiago, Chile
2011 - 2011
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Assistant Professor Full Time
UNIVERSIDAD DE CHILE
INTA
Santiago, Chile
2018 - A la fecha
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RESEARCHER ASSISTANT Part Time
INSTITUTE OF NUTRITION AND FOOD TECHNOLOGY
santiago, Chile
2008 - 2012
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Patent expert in biotechnology and pharmaceutic Part Time
JUVENAL HERNÁNDEZ S. LAW FIRM
Santiago, Chile
2002 - 2007
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RESEARCHER ASSISTANT Part Time
UNIVERSITY OF CHILE
Santiago, Chile
2010 - 2012
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RESEARCHER ASSISTANT Part Time
UNIVERSITY OF CHILE
Santiago, Chile
2007 - 2009
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RESEARCHER Part Time
INSTITUTE OF NUTRITION AND FOOD TECHNOLOGY
Santiago, Chile
2014 - 2016
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RESEARCHER Part Time
INSTITUTE OF NUTRITION AND FOOD TECHNOLOGY
Santiago, Chile
2016 - 2018
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RESEARCHER ASSISTANT Part Time
INSTITUTE OF NUTRITION AND FOOD TECHNOLOGY
SANTIAGO, Chile
2012 - 2016
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Profesor Asistente Full Time
UNIVERSITY OF CHILE
Santiago, Chile
2018 - A la fecha
Thesis direction.
2022 to 2023 Paulina Hernández Pino, Biotechnology Engineering major, Adres Bello University. Title: Role of stromal genomic damage in the progression of tumor malignancy.
2021 to 2023Pamela Marinao Tapia. Master in Nutrition and Food, Human Nutrition mention. University of Chile. Title: Identification of anti-inflammatory capacity in Chilean medicinal herbs: effect on jak/stat activity and glycemia.
Thesis co-direction.
2021 to 2023 María Jesús Vera Castillo. Master in Nutrition and Food, Human Nutrition mention. University of Chile. Title: Obesity and breast cancer: Effect of obesity-associated inflammation on the formation of a mammary pre-tumor niche.
2020 to 2023 Aldo Leyva Soto. Doctorate in Science and Engineering. Faculty of Chemical Sciences and Engineering. Autonomous University of Baja California, Mexico. Title: Evaluation of functional ingredient in mammalian cells and Drosophila melanogaster for prevention of chronic metabolic diseases.
2020 to 2022 Daniela Salgado Canales. Master in Nutrition and Food, Human Nutrition mention, INTA - Universidad de Chile. Title: Effect of time-restricted feeding on high-fat diet-induced metabolic dysfunction in Drosophila melanogaster.
2020 to 2021 Isidora Villagrán Varas. Degree in Biochemistry. Pontifical Catholic University of Chile. Title: Antioxidant Effect of Lampaya Medicinalis Extract Phil. (Verbenaceae) in HepG2 Hepatocytes exposed to Oleic and Palmitic Acid.
My relationship with society is based on my firm intention to collaborate in the generation of a population composed of critical individuals, in which science has a fundamental role. This conviction has been expressed mainly in my participation as a volunteer in the school science club program of the Explora program, in which I have participated as a tutor for last three years. My training in biotechnology and my studies in nutrition and food allow me to advise on topics of interest to young people and society, guiding their research under a public interest perspective but with a solid scientific base. Also, I have carried out some scientific dissemination activities in "science week" for schoolchildren at the San Agustín de Ñuñoa school. On the other hand, since 2021, I have participated in the INTA extension council, which advises the Extension Directorate on society and the environment. Finally, through this project, I also hope to generate educational material on breast cancer and the impact of a healthy diet in the prevention of non-communicable chronic diseases such as obesity, diabetes and cancer. My training with a multidisciplinary and collaborative approach allows me to offer a broad view of breast cancer and obesity, which I hope will be a contribution both in the generation of relevant basic knowledge and in education for the general population.
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Dr Abraham Stekel Scholarship
NESTLE CHILE S.A.
Chile, 2011
Young researcher
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National doctoral scholarship
COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA
Chile, 2012
scholarship for doctoral program
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Postdoctoral fellowship abroad Becas Chile 2022
ANID
Chile, 2022
Becas Chile #74220022
Soluble factors derived from tumor mammary cell lines induce a stromal mammary adipose reversion in human and mice adipose cells. Possible role of TGF-beta 1 and TNF-alpha |
A study of the role of smoke cigarette-induced DNA damage and extracellular matrix stiffness on establishing the pro-tumor microenvironment by mammary stromal cells |
Altered TGF-beta-integrin signaling in aged periodontal wound repair |
Disclosing the phosphorylation landscape of the host-pathogen interaction between Piscirickettsia salmonis and Atlantic salmon |
Empaquetamiento y puesta en marcha de Redoxcell, un servicio para evaluar el impacto antioxidante de matrices alimentarias en células vivas |
Desarrollo de un modelo animal para el estudio del efecto de la dieta sobre la respuesta inflamatoria promotora de la malignidad tumoral |
Redoxcell=> una plataforma para el registro del impacto antioxidante en células vivas |
EFECTO DE UNA DIETA ALTA EN GLUCOSA SOBRE LA CONDUCTA METASTÁSICA DE TUMORES DEL DISCO IMAGINAL DE LA LARVA DE DROSOPHILA MELANOGASTER. |
Uso de células que expresan un biosensor REDOX para evaluar la capacidad antioxidante de moléculas de interés nutricional y terapéutico. |
TRANSFORMING GROWTH FACTOR-BETA (TGF-BETA) FAVOURS TUMOUR GROWTH BY MODULATING INVASIVE, FIBROTIC AND IMMUNE RESPONSES IN HUMAN BREAST CANCER |
ESTUDIOS DEL PAPEL INSTRUCTIVO DEL ESTROMA CELULAR EN LA TUMORIGENESIS MAMARIA HUMANA. IDENTIFICACION DE MARCADORES TEMPRANOS DE MALIGNIDAD. |
LA ASOCIACION FUNCIONAL ENTRE LOS RECEPTORES DE EGF Y uPA Y LA MODULACION DE CADHERINA-E POR GTPasas DE LA FAMILIA Rho, SON FACTORES DETERMINANTES EN LA EXPRESION Y MANTENCION DEL FENOTIPO INVASIVO. |