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Cinthya Ruiz-Tagle

Research Assistant

Pontificia Universidad Católica de Chile

Santiago, Chile

Tuberculosis diagnosis, Tuberculosis biomarkers

Bachelor in Bioengineering, UNIVERSIDAD DE CONCEPCION. Chile, 2008
Bioengineering, UNIVERSIDAD DE CONCEPCION. Chile, 2009
Master in Biochemistry and Bioinformatics, UNIVERSIDAD DE CONCEPCION. Chile, 2010
PhD in Molecular Biosciences, UNIVERSIDAD ANDRES BELLO. Chile, 2016
Biostatistics, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2021
Statistics, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2022

Instructor Part Time

UNIVERSIDAD ANDRES BELLO

Faculty of Biological Sciences

Santiago, Chile

2011 - 2012
Teaching assistant Part Time

UNIVERSIDAD DE CONCEPCION

Faculty of Biological Sciences

Concepción, Chile

2009 - 2009

Research Assistant Full Time

Pontificia Universidad Católica de Chile

Santiago, Chile

2017 - A la fecha

National Doctoral Fellowship

CONICYT

Chile, 2010

Scholarship to finance doctoral studies at Chilean universities.
Scholarship to support the doctoral thesis

CONICYT

Chile, 2012

Scholarship to finance the development of the doctoral thesis - CONICYT 24120956.
Scholarship to support the doctoral thesis

UNIVERSIDAD ANDRES BELLO

Chile, 2012

Scholarship to finance the development of the doctoral thesis - UNAB DI-72-12 / I.
Exchange program (EULAMDIMA)

EULAMDIMA

Chile, 2014

Scholarship to finance the internships of the Exchange program (EULAMDIMA) at the University of Heidelberg (Mannheim, Germany).


Evaluation of concordance of new QuantiFERON-TB Gold Plus platforms for <i>Mycobacterium tuberculosis</i> infection diagnosis in a prospective cohort of household contacts Ruiz-Tagle, Cinthya; Garcia, Patricia; Hernandez, Mariluz; Balcells, Maria Elvira Article ISI MICROBIOLOGY SPECTRUM (2024)
Differential levels of anti-<i>Mycobacterium tuberculosis</i>-specific IgAs in saliva of household contacts with latent tuberculosis infection Ruiz-Tagle, Cinthya; Naves, Rodrigo; Garcia, Patricia; Guenther, Anna; Schneiderhan-Marra, Nicole; Balcells, Maria Elvira Article ISI FRONTIERS IN MEDICINE (2023)
Influence of SARS-CoV-2 mRNA Vaccine Booster among Cancer Patients on Active Treatment Previously Immunized with Inactivated versus mRNA Vaccines: A Prospective Cohort Study Mondaca, Sebastian; Walbaum, Benjamin; Le Corre, Nicole; Ferres, Marcela; Valdes, Alejandro; Martinez-Valdebenito, Constanza; Ruiz-Tagle, Cinthya; Macanas-Pirard, Patricia; Ross, Patricio; Cisternas, Betzabe; Perez, Patricia; Cabrera, Olivia; Cerda, Valentina; Ormazabal, Ivana; Barrera, Aldo; Prado, Maria E.; Venegas, Maria I.; Palma, Silvia; Broekhuizen, Richard; Kalergis, Alexis M.; Bueno, Susan M.; Espinoza, Manuel A.; Balcells, M. Elvira; Nervi, Bruno Article ISI VACCINES (2023)
Reduced microbial diversity of the nasopharyngeal microbiome in household contacts with latent tuberculosis infection Ruiz-Tagle, Cinthya; Ugalde, Juan A.; Naves, Rodrigo; Araos, Rafael; Garcia, Patricia; Balcells, Maria Elvira Article ISI SCIENTIFIC REPORTS (2023)
Humoral immune-response to a SARS-CoV-2-BNT162b2 booster in inflammatory arthritis patients who received an inactivated virus vaccine Duran, Josefina; Isabel Burgos, Paula; Le Corre, Nicole; Ruiz Tagle, Cinthya; Martinez-Valdebenito, Constanza; Castro, Mauricio; Metcalfe, Valentina; Niemann, Paula; Elvira Balcells, M. Article ISI ANNALS OF THE RHEUMATIC DISEASES (2022)
Reduced immune response to inactivated SARS-CoV-2 vaccine in a cohort of immunocompromised patients in Chile Balcells, María Elvira; Le Corre, Nicole; Durán, Josefina; Ceballos, María Elena; et al. Article CLINICAL INFECTIOUS DISEASES (2022)
SARS-CoV-2 vaccine booster in solid organ transplant recipients previously immunised with inactivated versus mRNA vaccines: A prospective cohort study Dib, Martin; Le Corre, Nicole; Ortiz, Catalina; Garcia, Daniel; Ferres, Marcela; Martinez-Valdebenito, Constanza; Ruiz-Tagle, Cinthya; Jose Ojeda, Maria; Espinoza, Manuel A.; Jara, Aquiles; Pablo Arab, Juan; Rabagliati, Ricardo; Vizcaya, Cecilia; Elena Ceballos, Maria; Sarmiento, Mauricio; Mondaca, Sebastian; Vinuela, Macarena; Pastore, Antonia; Szwarcfiter, Vania; Galdames, Elizabeth; Barrera, Aldo; Castro, Pablo; Galvez, Nicolas M. S.; Soto, Jorge A.; Bueno, Susan M.; Kalergis, Alexis M.; Nervi, Bruno; Elvira Balcells, M. Article ISI LANCET REGIONAL HEALTH-AMERICAS (2022)
Vitamin D and cathelicidin levels and susceptibility to Mycobacterium tuberculosis infection acquisition in household contacts Ruiz-Tagle, Cinthya; Romero, Francisco; Naves, Rodrigo; Balcells, María Elvira Article ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA (2022)
Systematic screening of adult household contacts of patients with active pulmonary tuberculosis reveals high rates of new infections during follow-up Elvira Balcells, Maria; Carvajal, Camila; Fernandez, Paula; Ruiz-Tagle, Cinthya; Pizarro, Alejandra; Garcia, Patricia; Pena, Carlos; Cuevas, Gerardo; Naves, Rodrigo Article ISI REVISTA MEDICA DE CHILE (2020)
Unraveling the Role of MicroRNAs in Mycobacterium tuberculosis Infection and Disease: Advances and Pitfalls Ruiz-Tagle, Cinthya; Naves, Rodrigo; Balcells, María Elvira; Ottemann, Karen M. Article ISI SCOPUS INFECTION AND IMMUNITY (2020)
Diagnostic performance of GM-CSF and IL-2 in response to long-term specific-antigen cell stimulation in patients with active and latent tuberculosis infection Balcells, ME; Ruiz-Tagle, C; Tiznado, C; Garcia, P; Naves R. Article ISI SCOPUS TUBERCULOSIS (2018)
Recruitment and subnuclear distribution of the regulatory machinery during 1 alpha,25-dihydroxy vitamin D-3-mediated transcriptional upregulation in osteoblasts Arriagada, G; Henriquez, B; Moena D.; Merino, P; Ruiz-Tagle, C; Lian, JB; Stein, GS; Stein, JL; Montecino, M. Article ISI SCOPUS JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2010)


Differential contribution of p160/SRC and DRIP/TRAP coactivator complexes during vitamin D-dependent up-regulation of target genes in osteoblastic cells Moena, Daniel; Merino, Paola; Ruiz-Tagle, Cinthya G.; Lian, Jane B; Stein, Garry S; Stein, Janet L.; Montecino, Martin A. ConferencePaper (2010)


Effectiveness of a respiratory bundle to reduce tuberculosis transmission within households: interim analysis of a prospective, multicentre, controlled trial Balcells, María Elvira; Ruiz-Tagle, Cinthya G.; Seguel, Romina J.; Villarroel, Luis A.; Bernales, Margarita; Vargas-García, Salvador; Pizarro, Alejandra V.; Peña, Carlos; Neira, Víctor; Nathavitharana, Ruvandhi; García, Patricia ConferencePoster (2024)
Prevalence of transmitted resistance to antiretroviral therapy in Chile: preliminary results Ceballos, María Elena; Ruiz-Tagle, Cinthya G.; Castañeda, Felipe M.; Ferrés, Marcela V.; Palma, Carlos A.; Domínguez de L, María Angélica; Espinoza, Manuel A.; Afani, Alejandro E.; Balcells, María Elvira ConferencePoster (2023)
Evaluation of a new lateral flow assay for the detection of interferon gamma in the diagnosis of latent tuberculous infection: preliminary results Ruiz-Tagle, Cinthya G.; Flores, Diego; Barril, Paulina; Román, Juan C.; Hernández, Mariluz; Balcells, María Elvira; García, Patricia ConferencePoster (2022)
Nasopharynx microbiome composition in household contacts upon Mycobacterium tuberculosis exposure Ruiz-Tagle, Cinthya G.; Ugalde, Juan A.; Naves, Rodrigo A.; Araos, Rafael; García, Patricia; Balcells, María E. ConferencePoster (2022)
New automated methodology for the detection of interferongamma by chemiluminescence reduces the indeterminate results of the latent tuberculosis test García, Patricia; Wosniak, Aniela; Vásquez, Manuel; Marchant, Silvia; Román, Juan C.; Ruiz-Tagle, Cinthya G.; Balcells, María Elvira ConferencePoster (2022)
Tuberculosis pulmonar ¿Cuánto saben y qué medidas implementan los contactos intradomiciliarios para prevenir el contagio dentro del hogar? Seguel, Romina J.; Ruiz-Tagle, Cinthya G.; Vargas, Salvador; Bernales, Margarita; Villarroel, Luis A.; Pizarro, Alejandra V.; Peña, Carlos; Hernández, Víctor; Neira, Víctor; Dinamarca, Eduardo; Balcells, María Elvira ConferencePoster (2022)
Immune response to inactivated vaccine against SARS-CoV-2 in a cohort of immunocompromised patients in Chile. Balcells, María Elvira; Le Corre, Nicole; Durán, Josefina; Ceballos, María Elena; et al. ConferencePoster (2021)
Detection of antibodies against specific antigens of Mycobacterium tuberculosis in saliva samples in patients with active pulmonary tuberculosis, a pilot study Ruiz-Tagle, Cinthya; Guenther, Anna; Schneiderhan-Marra, Nicole; Lizama, Luis; Naves, Rodrigo; Balcells, María Elvira ConferencePoster (2020)
Active and prolonged screening reveals high number of secondary cases of tuberculosis in adult contacts Carvajal, Camila; Fernández, Paula; Pizarro, Alejandra; García, Patricia; Ruiz-Tagle, Cinthya; Peña, Carlos; Cuevas, Gerardo; Naves, Rodrigo; Balcells, María Elvira ConferencePoster (2020)
Antibody detection against Mycobacterium tuberculosis antigens in saliva from patients with active pulmonary tuberculosis Ruiz-Tagle, Cinthya; Naves, Rodrigo; Balcells, María Elvira ConferencePoster (2020)
MiRNAs differential expression pattern distinguishes uninfected household contacts from those with newly acquired latent tuberculosis infection Ruiz-Tagle, Cinthya; Naves, Rodrigo; Balcells, María Elvira ConferencePoster (2020)
Early tuberculosis infections assessed by serial QuantiFERON TB-Gold Plus testing in a prospective cohort of household contacts Balcells, María Elvira; Naves, Rodrigo; García, Patricia; Ruiz-Tagle, Cinthya; Carvajal, Camila; Fernández, Paula; Peña, Carlos ConferencePoster (2018)
Association of VDR with the nuclear matrix: Identification of specific domains Ruiz-Tagle, Cinthya; Montecino, Martín ConferencePoster (2013)
Domains in the Vitamin D receptor that mediate interactions with the nuclear matrix in osteoblasts Ruiz-Tagle, Cinthya; Montecino, Martín ConferencePoster (2013)
Developing methodologies to obtain soluble nuclear matrix protein components associated with vitamin D-mediated transcriptional response in osteoblasts Ruiz-Tagle, Cinthya; Montecino, Martín ConferencePoster (2012)
Differential contribution of p160/SRC and DRIP/TRAP co-activator complexes during vitamin D-dependent up-regulation of target genes in osteoblastic cell Moena, Daniel; Merino, Paola; Ruiz-Tagle, Cinthya; Montecino, Martín ConferencePoster (2010)
Differential contribution of p160/SRC and DRIP/TRAP co-activator complexes during vitamin D-dependent up-regulation of target genes in osteoblastic cells Moena, Daniel; Merino, Paola; Ruiz-Tagle, Cinthya; Lian, Jane B; Stein, Gary S.; Stein, Janet L.; Montecino, Martín ConferencePoster (2010)
Optimization of methodologies for the production and analysis of the vitamin D receptor obtained by the baculovirus system Ruiz-Tagle, Cinthya; Bruna, Carola; Montecino, Martín ConferencePoster (2009)
Recruitment and subnuclear distribution of the regulatory machinery during 1α,25-dihydroxyvitamin D3-mediated transcriptional activation in osteoblastic cells Arriagada, Gloria; Henríquez, Berta; Merino, Paola; Moena, Daniel; Ruiz-Tagle, Cinthya; van Wijnen, Andre J.; Lian, Jane B; Stein, Janet L.; Stein, Gary S.; Montecino, Martín ConferencePoster (2009)


PREVALENCIA DE RESISTENCIA TRANSMITIDA A TERAPIA ANTIRRETROVIRAL EN PACIENTES PORTADORES DE VIH VÍRGENES A TRATAMIENTO EN CHILE: IMPLICANCIAS PARA LA POLÍTICA PÚBLICA Ceballos, María Elena Proyecto (2022)
EVALUATION OF THE IMMUNE RESPONSE TO THE INACTIVATED SARS-COV-2 VACCINE IN A COHORT OF ADULT PATIENTS WITH SEVERE ACQUIRED IMMUNOSUPPRESSION Balcells María Elvira; Nervi, Bruno Proyecto (2021)
STRENGTHENING OF AIRBORNE PREVENTIVE MEASURES INSIDE HOUSEHOLDS OF PULMONARY TB CASES AS A TOOL TO REDUCE NEW INFECTIONS IN CLOSE CONTACTS. A PILOT, CONTROLLED, PRE-POST STUDY Balcells, María Elvira Proyecto (2021)
DETERMINANTS FOR TUBERCULOSIS INFECTION ACQUISITION IN CONTACTS: EXPLORING THE ROLE OF NASOPHARYNGEAL MUCOSAL ENVIRONMENT Balcells, María Elvira Proyecto (2017)
C/EBPBETA-MEDIATED CONTROL OF TRANSCRIPTION DURING OSTEOBLAST DIFFERENTIATION Montecino, Martín Proyecto (2013)
MECHANISMS THAT CONTROL TRANSCRIPTIONAL RESPONSIVENESS TO 1a,25-DIHYDROXY VITAMIN D3 IN OSTEOBLASTS Montecino, Martín Proyecto (2009)