Man

Sebastián Andrés Fuentes Retamal

Investigador Postdoctoral

Universidad de Chile

Santiago, Chile

Líneas de Investigación


metabolismo del cáncer, terapias dirigidas hacia la mitocondria, plasticidad mitocondrial

Educación

  •  Farmacología, UNIVERSIDAD DE CHILE. Chile, 2020
  •  Químico farmacéutico, UNIVERSIDAD DE CHILE. Chile, 2015

Experiencia Académica

  •   Docente Part Time

    UNIVERSIDAD DIEGO PORTALES

    Facultad de Salud y odontología

    Santiago, Chile

    2017 - 2017

  •   Docente Part Time

    UNIVERSIDAD ANDRES BELLO

    Facultad de Medicina

    Santiago, Chile

    2018 - A la fecha

  •   Docente Part Time

    UNIVERSIDAD DE CHILE

    Facultad de Medicina

    Santiago, Chile

    2018 - 2019

  •   Docente Part Time

    UNIVERSIDAD DE CHILE

    Facultad de Ciencias veterinarias y pecuarias

    Santiago, Chile

    2020 - A la fecha

  •   Docente Part Time

    UNIVERSIDAD DE CHILE

    Facultad de Medicina

    Chile

    2021 - A la fecha

Experiencia Profesional

  •   Docente Part Time

    Universidad Andrés Bello

    Chile

    2018 - A la fecha

  •   Docente Part Time

    Universidad de Chile

    Chile

    2018 - A la fecha

  •   Docente Part Time

    Universidad Diego Portales

    Chile

    2017 - 2017

Formación de Capital Humano


Dirección de tesis y seminarios de tílulo



 

Article (14)

A paraguayan toad <i>Rhinella schneideri</i> preparation based on Mbya tradition increases mitochondrial bioenergetics with migrastatic effects dependent on AMPK in breast cancer cells
Functional, immunological characterization, and anticancer activity of BaMtx: A new Lys49-PLA<sub>2</sub> homologue isolated from the venom of Peruvian <i>Bothrops atrox</i> snake (Serpentes: Viperidae)
Shedding Light on the Dentition and Venom Delivery System of the Rear-Fanged Snake, Galvarinus chilensis chilensis (Serpentes: Dipsadidae: Tachymenini) from Chile
Aspirin-triggered resolvin D1 reduces parasitic cardiac load by decreasing inflammation in a murine model of early chronic Chagas disease
Extracellular Matrix Signals as Drivers of Mitochondrial Bioenergetics and Metabolic Plasticity of Cancer Cells During Metastasis
FRI-1 Is an Anti-Cancer Isoquinolinequinone That Inhibits the Mitochondrial Bioenergetics and Blocks Metabolic Shifts by Redox Disruption in Breast Cancer Cells
An acylhydroquinone derivative produces OXPHOS uncoupling and sensitization to BH3 mimetic ABT-199 (Venetoclax) in human promyelocytic leukemia cells
Complex Mitochondrial Dysfunction Induced by TPP+-Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast Cancer Cells
Novel benzoate-lipophilic cations selectively induce cell death in human colorectal cancer cell lines
Simvastatin Improves Cardiac Function through Notch 1 Activation in BALB/c Mice with Chronic Chagas Cardiomyopathy
The Parotoid Gland Secretion from Peruvian Toad Rhinella horribilis (Wiegmann, 1833): Chemical Composition and Effect on the Proliferation and Migration of Lung Cancer Cells
Antiproliferative and proapoptotic activities of aza-annulated naphthoquinone analogs
Derivatives of alkyl gallate triphenylphosphonium exhibit antitumor activity in a syngeneic murine model of mammary adenocarcinoma
Destabilization of mitochondrial functions as a target against breast cancer progression: Role of TPP+-linked-polyhydroxybenzoates

BookSection (1)

Chapter 1 - Recent advances in molecular mechanisms of anticancer natural products that target mitochondrial bioenergetics

Proyecto (6)

α-KGDH inhibition prevents triple-negative breast cancer cell migration by mitophagy induction: a potential anti-cancer target.
Lipophilic cations of esters of alkyltriphenylphosphonium polyhydroxybenzoates as mitochondriotropic antineoplastic agents. Antitumoral activity spectra on human tumour cells from different tissues
Estudio de mecanismos de acción de cationes lipofílicos deslocalizados derivados de alquil-polihidroxibenzoatos unidos al grupo trifenilfosfonio como antineoplásicos de acción mitocondrial.
Lipophilic cations of esters of alkyltriphenylphosphonium polyhydroxybenzoates as mitochondriotropic antineoplastic agents. Antitumoral activity spectra on human tumour cells from different tissues.
Regio- and stereo-selective Diels-Alder reactions in the synthesis of CDC25B fosfatase inhibitors.
A rational synthetic approach to 3-indolealkyl(aryl)piperazine derivatives as new hetero and homobivalent ligands with potential serotonergic activity.
16
Sebastián Fuentes

Investigador Postdoctoral

Institulo de Ciencias Biomédicas - Instituto de investigación en Ciencias Odontológicas

Universidad de Chile

Santiago, Chile

4
Juan Maya

Full Professor

Biomedical Sciences Institute

UNIVERSIDAD DE CHILE

Santiago, Chile

3
Jorge Ferreira

Director

Clinic and Molecular Farmacology

UNIVERSIDAD DE CHILE , FACULTAD DE MEDICINA, ICBM

Santiago, Chile

3
Félix Urra

Profesor asistente

Facultad de Medicina, Instituto de Ciencias Biomédicas, Programa de Farmacología Molecular y Clínica

University of Chile

Santiago, Chile

2
Fabiola González

Investigadora Postdoctoral

Universidad de Chile

Santiago, Chile

2
Ulrike Kemmerling

Full Professor

ICBM

Facultad de Medicina, Universidad de Chile

Santiago, Chile

2
José Jara

Assistant Professor

Research Institute of Dental Sciences

Universidad de Chile

Santiago, Chile

1
Cristian Suárez

Investigador Postdoctoral Fondecyt Postdoctorado 2022 N° 3220509

Universidad del Desarrollo

Santiago, Chile

1
Rodrigo Pulgar

Profesor/Investigador asistente

INTA

UNIVERSIDAD DE CHILE - INSTITUTO DE NUTRICION Y TECNOLOGIA DE ALIMENTOS

Santiago, Chile

1
JEAN DE ANDRADE

Académico Docente

Departamento de Medicina Traslacional

Universidad Católica del Maule

Talca, Chile

1
Bruce Cassels

Profesor Titular

Departamento de Química

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS, DEPARTAMENTO DE QUÍMICA

Santiago, Chile

1
JAIME MELLA

PROFESOR ADJUNTO

INSTITUTO DE QUIMICA Y BIOQUIMICA

UNIVERSIDAD DE VALPARAISO

VALPARAISO, Chile

1
Claudia Yáñez

académico

Química Orgánica y Físico Química

Universidad de Chile

Santiago, Chile

1
Guillermo Schmeda

Profesor Titular

UNIVERSIDAD DE TALCA

Talca, Chile

1
Gloria Calaf

Directora Laboratorio Biología del cáncer

Universidad de Tarapacá

Arica, Chile

1
Guillermo Díaz

Académico

Química Farmacológica y Toxicológica

UNIVERSIDAD DE CHILE, FACULTAD DE CIENCIAS QUÍMICAS Y FARMACÉUTICAS

Santiago, Chile

1
Ramiro Araya Maturana

Profesor Titular

Universidad de Talca

SantiaTalcago, Chile