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Vasko Kramer

Head of R&D

Positronmed Ltd. (Prestaciones Medicas AyC Ltda.)

Santiago, Chile

Investigación y desarrollo de radiofármacos para la obtención de imágenes PET y el tratamiento en oncología. Investigación traslacional de radiofármacos y coordinación de estudios clínicos en estrecha colaboración con especialidades asociadas.

Química radiofarmaceutica, Johannes Gutenberg-Universidad Mainz. Alemania, 2012
Quimica, Johannes Gutenberg-Universidad Mainz. Chile, 2008

Asistente cientifico Full Time

JOHANNES GUTENBERG UNIVERSITAT MAINZ

Quimica

Mainz, Alemania

2008 - 2012

Asesor I+D Part Time

Positronmed Ltda

Santiago, Chile

2013 - A la fecha
Gerente I+D Part Time

Positronpharma SA

Santiago, Chile

2012 - A la fecha
Gerente General Other

Acrux Radiopharma Consulting SpA

Santiago, Chile

2012 - A la fecha

Co-Organizer of the Theranostic World Congress (TWC) 2022 in Wiesbaden:
https://www.twc-2022.org/


Al[F-18]F-NOTA-Octreotide Is Comparable to [Ga-68]Ga-DOTA-TATE for PET/CT Imaging of Neuroendocrine Tumours in the Latin-American Population Haeger, Arlette; Soza-Ried, Cristian; Kramer, Vasko; Hurtado de Mendoza, Ana; Eppard, Elisabeth; Emmanuel, Noemie; Wettlin, Johanna; Amaral, Horacio; Fernandez, Rene Article ISI CANCERS (2023)
Head-to-Head Intra-Individual Comparison of Biodistribution and Tumor Uptake of [18F]FAPI-74 with [18F]FDG in Patients with PDAC: A Prospective Exploratory Study Novruzov, Emil; Giesel, Frederik; Mori, Yuriko et al. Article CANCERS (2023)
Synthesis and in vivo evaluation of [C-11]tucatinib for HER2-targeted PET imaging Mueller, Marius; Shalgunov, Vladimir; Hvass, Lars; Jorgensen, Jesper T.; Kramer, Vasko; Staudt, Markus; Battisti, Umberto Maria; Kjaer, Andreas; Herth, Matthias M. Article ISI BIOORGANIC MEDICINAL CHEMISTRY LETTERS (2023)
Development and evaluation of an 18F-labeled nanobody to target SARS-CoV-2's spike protein Lopes van den Broek, Sara, García-Vázquez, Rocío, Andersen, Ida Vang, Valenzuela-Nieto, Guillermo, Shalgunov, Vladimir, Battisti, Umberto M. et al. Article Frontiers in Nuclear Medicine (2022)
Whole-body biodistribution and radiation dosimetry of [F-18]PR04.MZ: a new PET radiotracer for clinical management of patients with movement disorders Lehnert, Wencke; Riss, Patrick J.; de Mendoza, Ana Hurtado; Lopez, Sandra; Fernandez, Gonzalo; Ilheu, Marcelo; Amaral, Horacio; Kramer, Vasko Article ISI EJNMMI RESEARCH (2022)
A theranostic approach of [68Ga] Ga-DOTA. SA. FAPi PET/CT-guided [177Lu] Lu-DOTA. SA. FAPi radionuclide therapy in an end-stage breast cancer patient: new frontier in targeted … Ballal, S; Yadav, MP; Kramer, V; Moon, ES; Roesch, F; Tripathi, Mayank; ArunRaj, ST; Bal, CS Article EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2021)
Biodistribution and dosimetry of a single dose of albumin-binding ligand [177Lu] Lu-PSMA-ALB-56 in patients with mCRPC Kramer, V; Fernandez, R; Wencke, L; Jimenez-Franco, DL; Soza-Ried C.; Eppard E.; Ceballos, M; Meckel, M; Benesova, M; Umbricht, C; Kluge, A; Schibli, R; Zhernosekov, K; Schibli, R; Mueller, C Article EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2021)
Biodistribution, pharmacokinetics, dosimetry of [68Ga] Ga-DOTA. SA. FAPi, and the head-to-head comparison with [18F] F-FDG PET/CT in patients with various cancers Ballal S.; Yadav, MP; Moon, ES; Kramer, V; Roesch, F; Kumari, S; Tripathi, M; ArunRaj, T; Sarswat, S; Bal, CS Article EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2021)
Evaluation of Safety and Dosimetry of 177Lu-DOTA-ZOL for Therapy of Bone Metastases Fernandez, R; Eppard, E; Wencke, L; Jimenez-Franco, LD; Soza-Ried, C; Ceballos, M; Ribbeck, J; Kluge, A; Roesch, F; Meckel, M; Zhernosekov, K; Kramer, V; Amaral, H Article JOURNAL OF NUCLEAR MEDICINE (2021)
FAP and FAPI-PET/CT in Malignant and Non-Malignant Diseases: A Perfect Symbiosis? Dendl, K; Koerber, S; Kratochwil, C; Cardinale, J; Fink, R; Dabir, M; Novruzov, E; Watabe, T; Kramer, V; Choyke, P; Haberkorn, U; Giesel, FL Article Pharmaceuticals (2021)
First-In-Human Results on the Biodistribution, Pharmacokinetics, and Dosimetry of [177Lu]Lu-DOTA.SA.FAPi and [177Lu]Lu-DOTAGA.(SA.FAPi)2 Ballal, S; Yadav, MP; Moon, ES; Kramer, V; Roesch, F; Kumari, S; Bal, CS Article Pharmaceuticals (2021)
Characterization of the serotonin 2A receptor selective PET tracer (R)-[F-18]MH.MZ in the human brain Kramer V.; Dyssegaard A.; Flores J.; Soza-Ried C.; RÃ¶sch F.; Knudsen G.M.; Amaral H.; Herth M.M. Article ISI SCOPUS EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2020)
Evaluation of [F-18]-N-Methyl lansoprazole as a Tau PET Imaging Agent in First-in-Human Studies Kramer V.; Brooks A.F.; Haeger A.; Kuljis R.O.; Rafique W.; Koeppe R.A.; Raffel D.M.; Frey K.A.; Amaral H.; Scott P.J.H.; Riss P.J. Article ISI SCOPUS ACS Chemical Neuroscience (2020)
Detection Efficacy of F-18-PSMA-1007 PET/CT in 251 Patients with Biochemical Recurrence of Prostate Cancer After Radical Prostatectomy Giesel, FL; Knorr, K; Spohn, F; Will, L; Maurer, T; Flechsig, P; Neels, O; Schiller, K; Amaral, H; Weber, WA; Haberkorn, U; Schwaiger, M; Kratochwil, C; Choyke, P; Kramer, V; Kopka, K; Eiber, M Article ISI SCOPUS JOURNAL OF NUCLEAR MEDICINE (2019)
Pharmacokinetic evaluation of [F-18]PR04.MZ for PET/CT imaging and quantification of dopamine transporters in the human brain Kramer V.; Juri C.; Riss P.J.; Pruzzo R.; Soza-Ried C.; Flores J.; Hurtado A.; RÃ¶sch F.; Chana-Cuevas P.; Amaral H. Article ISI SCOPUS EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2019)
Image-Guided Development of Heterocyclic Sulfoxides as Ligands for Tau Neurofibrillary Tangles: From First-in-Man to Second-Generation Ligands Rafique, W; Kramer, V; Pardo, T; Smits, R; Spilhaug, MM; Hoepping, A; Savio, E; Engler, H; Kuljs, R; Amaral, H; Riss, PJ Article ISI SCOPUS ACS OMEGA (2018)
F-18-Labeling and evaluation of novel MDL 100907 derivatives as potential 5-HT2A antagonists for molecular imaging Debus, Fabian; Herth, Matthias M.; Piel, Markus; Buchholz, Hans-Georg; Bausbacher, Nicole; Kramer, Vasko; Lueddens, Hartmut; Roesch, Frank Article ISI NUCLEAR MEDICINE AND BIOLOGY (2010)
Structural Combination of Established 5-HT2A Receptor Ligands: New Aspects of the Binding Mode Kramer, Vasko; Herth, Matthias M.; Santini, Martin A.; Palner, Mikael; Knudsen, Gitte M.; Roesch, Frank Article ISI CHEMICAL BIOLOGY & DRUG DESIGN (2010)
Synthesis and in vitro affinities of various MDL 100907 derivatives as potential F-18-radioligands for 5-HT2A receptor imaging with PET Herth, Matthias M.; Kramer, Vasko; Piel, Markus; Palner, Mikael; Riss, Patrick J.; Knudsen, Gitte M.; Roesch, Frank Article ISI BIOORGANIC & MEDICINAL CHEMISTRY (2009)


[18F] PR04.MZ for Dopamine Transporter Quantification in Low Density Regions - Complete Evaluation and Dosimetry in Healthy Volunteers Kramer V.; Pruzzo R.; Hernandez, E.; Chana, P; Juri C.; Riss, P; Rosch, F; Amaral H. Abstract ISI EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2015)
Quantification of 5HT2A-Receptors in the Human Brain with [18F]MHMZ Kramer V.; Herth, M; Hernandez, E.; Juri C.; Pruzzo R.; Rosch, F; Amaral H. Abstract ISI EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2015)
[18F]PR04. MZ for Quantification of Striatal and Extrastriatal Dopamine Transporters in Patients with Idiopathic Parkinson's Disease Amaral H.; Kramer V.; Pruzzo R.; Chana, P; Juri C.; Piel M.; Galaz, R; Coudeu, I; Rosch, F Abstract ISI EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2013)


Imaging Nigrostriatal Dopaminergic Deficit in Holmes Tremor with F-18-PR04.MZ-PET/CT Juri C.; Chana, P; Kramer V.; Pruzzo R.; Amaral H.; Riss, PJ; Rosch, F EditorialMaterial ISI CLINICAL NUCLEAR MEDICINE (2015)


A new production method for a radioisotope used for non-invasive diagnose and monitoring of prostate cancer CORFO (16ITE2-67729) Proyecto 2017-2019 Coinvestigador(a)
Manifestaciones prodrómicas de la Enfermedad de Parkinson en un grupo de alto riesgo=> personas con síndrome de microdeleción 22q11.2 FONDECYT (FONDECYT 1) Proyecto 2017-2020 Coinvestigador(a)
Radiopharmaceuticals to visualize neurofibrillary tangles in vivo CORFO (14IEAT-28666) Proyecto 2014-2018 Investigador(a)
Desarrollo, Implementación y Validación Clínica de Radiofármacos para la Detección Temprana y Diferencial de la Enfermedad de Parkinson mediante Neuroimágenes PET/CT para el Mercado Nacional e Internacional CORFO (13PEI21682) Proyecto 2013-2017 Investigador(a)
Extrastriatal Dopaminergic Function in REM Sleep Behavioral Disorder FONDECYT (11130534) Proyecto 2013-2016 Personal técnico y/o de apoyo

Vasko Kramer

Head of R&D

Investigación y Desarrollo

Positronmed Ltd. (Prestaciones Medicas AyC Ltda.)

Santiago, Chile

CARLOS JURI

ASSISTANT PROFESSOR

NEUROLOGY

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

Pedro Chana Cuevas

Profesor Titular

Facultad de Ciencias Medicas

Universidad de Santiago

Santiago, Chile

Vasko Kramer

Líneas de Investigación

Educación

Química radiofarmaceutica, Johannes Gutenberg-Universidad Mainz. Alemania, 2012

Quimica, Johannes Gutenberg-Universidad Mainz. Chile, 2008

Experiencia Académica

Asistente cientifico Full Time

Experiencia Profesional

Asesor I+D Part Time

Gerente I+D Part Time

Gerente General Other

Difusión y Transferencia

Article (19)

Abstract (3)

EditorialMaterial (1)

Proyecto (5)

A new production method for a radioisotope used for non-invasive diagnose and monitoring of prostate cancer

Manifestaciones prodrómicas de la Enfermedad de Parkinson en un grupo de alto riesgo=> personas con síndrome de microdeleción 22q11.2

Radiopharmaceuticals to visualize neurofibrillary tangles in vivo

Desarrollo, Implementación y Validación Clínica de Radiofármacos para la Detección Temprana y Diferencial de la Enfermedad de Parkinson mediante Neuroimágenes PET/CT para el Mercado Nacional e Internacional

Extrastriatal Dopaminergic Function in REM Sleep Behavioral Disorder