Man

Marcelo Chacon

Postdoc

UTHealth

Houston, Estados Unidos

Líneas de Investigación


Huntington's disease, studying electrophysiological mechanisms that underlay early symptomatic alteration in striatal neurons. Alzheimer's disease, working on the aggregation of Tau protein as a cellular response to brain damage.

Educación

  •  Cellular and Molecular Biology, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2007
  •  Biological Sciences, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 1999

Experiencia Académica

  •   Postdoc Full Time

    PRINCETON UNIVERSITY

    Estados Unidos

    2009 - 2011

  •   Postdoc Full Time

    ALBERT EINSTEIN COLLEGE OF MEDICINE

    Estados Unidos

    2011 - 2016

  •   Postdoc Full Time

    UNIVERSITY OF TEXAS MEDICAL SCHOOL AT HOUSTON

    Estados Unidos

    2016 - A la fecha


 

Article (13)

Rescue of homeostatic regulation of striatal excitability and locomotor activity in a mouse model of Huntington's disease
MHC class I protein is expressed by neurons and neural progenitors in mid-gestation mouse brain
Frizzled-1 is involved in the neuroprotective effect of Wnt3a against a beta oligomers
The functional links between prion protein and copper
Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu
Acetylcholinesterase-A beta complexes are more toxic than A beta fibrils in rat hippocampus - Effect on rat beta-amyloid aggregation, laminin expression, reactive astrocytosis, and neuronal cell loss
beta-sheet breaker peptide prevents A beta-induced spatial memory impairments with partial reduction of amyloid deposits
The N-terminal copper-binding domain of the amyloid precursor protein protects against Cu2+ neurotoxicity in vivo
A human prion protein peptide (PrP59-91) protects against copper neurotoxicity
Acetylcholinesterase induces neuronal cell loss, astrocyte hypertrophy and behavioral deficits in mammalian hippocampus
Activation of Wnt signaling and behavioral impairments rescues neurodegeneration induced by beta-amyloid fibrils
The human prion octarepeat fragment prevents and reverses the inhibitory action of copper in the P2X(4) receptor without modifying the zinc action
Wnt signaling involvement in beta-amyloid-dependent neurodegeneration

Abstract (2)

Neuroprotective properties of copper binding fragments of amyloid precursor protein and prion
Neuroprotective properties of copper binding fragments of APP and PrP against copper toxicity

ConferencePaper (1)

Expression of Wnt receptors, frizzled, in rat neuronal cells
16
Marcelo Chacon

Postdoc

Neurology

UTHealth

Houston, Estados Unidos

13
Nibaldo Inestrosa

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

6
Maria Barria

Investigador, Associate Professor

Universidad San Sebastián

Puerto Montt, Chile

4
Ariel Reyes

Director de Departamento

Ciencias Biológicas

UNIVERSIDAD ANDRÉS BELLO

Santiago, Chile

2
Waldo Cerpa

Profesor Asociado

Biología Celular y Molecular

Pontificia Universidad Catolica de Chile

Santiago, Chile

2
Lorena Varela

Assistant Professor

Biological Sciences

Universidad Andres Bello

Santiago, Chile

2
Jose Garrido

Investigador asesor, part time

Universidad San Sebastián

Puerto Montt, Chile

2
Giancarlo De Ferrari

Full Professor

Biological Sciences

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

1
Aldo Villalon

Director Académico/Profesor Asistente

Ciencias de la Salud

Universidad de Aysén

Coyhaique, Chile

1
Gonzalo Olivares

ASSISTANT PROFESSOR

NEUROCIENCIA

Universidad de Chile

SANTIAGO, Chile

1
Juan Godoy

Investigador

Centro de Oncologia dePrecision

Santiago, Chile

1
Genevieve Merabachvili

Profesor Asistente

salud

Universidad Santo Tomás

Santiago, Chile

1
Francisco Aboitiz

Profesor

Psychiatry

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

santiago, Chile

1
Francisco Bozinovic

Full professor

Ecology

Pontifical Catholic University of Chile

Santiago, Chile

1
Rebeca Aldunate

Profesor Titular

Ciencias

UNIVERSIDAD SANTO TOMÁS

Santiago, Chile

1
Juan Montiel

Profesor Titular

FACULTAD DE MEDICINA

UNIVERSIDAD DIEGO PORTALES

Santiago, Chile

1
Mauricio Gonzalez

Profesor Titular

INTA

UNIVERSIDAD DE CHILE - INSTITUTO DE NUTRICION Y TECNOLOGIA DE ALIMENTOS

Santiago, Chile