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Alvaro Oscar Ardiles Araya

Full Professor

Universidad de Valparaíso

Valparaiso, Chile

Neuroscience, Synaptic physiology, Behavioral neuroscience, Neuromodulation, Aging and Neurodegeneration, Panexin 1 channels activity, Molecular mechanisms of Synaptopathies, Alzheimer´s disease, neuronal cytoskeleton.

Neuroscience, UNIVERSIDAD DE VALPARAISO. Chile, 2011
Biochemist, PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO. Chile, 2006
Biochemistry, PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO. Chile, 2005

Assistant professor Full Time

UNIVERSIDAD DE VALPARAISO

MEDICINA

Valparaiso, Chile

2017 - 2023
Lecturer professor Other

Universidad Andrés Bello

Ciencias Biológicas

Viña del mar, Chile

2011 - 2012
Full professor Full Time

UNIVERSIDAD DE VALPARAISO

Medicina

Valparaiso, Chile

2023 - A la fecha

Young associate researcher Part Time

Centro Interdisciplinario de Neurociencia

Valparaiso, Chile

2015 - 2020
Postdoctoral researcher Full Time

Universidad de Valparaiso

Valparaiso, Chile

2012 - 2015
Lecturer professor Other

Universidad Andres bello

Valparaiso, Chile

2011 - 2012
Research assistant Full Time

Centro Interdisciplinario de Neurociencia

Valparaiso, Chile

2005 - 2007
Adjunct researcher Part Time

Centro Interdisciplinario de Neurociencia de Valparaiso

Valparaiso, Chile

2021 - A la fecha

5 PhD thesis, 4 Master Thesis, and 13 Undergraduate thesis directed or co-directed.
Undergraduate
2013-2014 (Biotechnology) Oriana Ramírez Herrera. Universidad Andrés Bello
2015-2016 (Biochemistry) Francisca García Rojas. Pontificia Universidad Católica de Valparaíso.
2018-2019 (Medical technologist) Barbara Gomez and Elena Mery. Universidad de Valparaiso
2019-2020 (Medical technologist) Nicolas Rivera. Universidad de Valparaiso
2020-2022 (Medical technologist) Katherine Allende, Mayra Providell y Juan Pablo Pinochet. Universidad de Valparaiso
2021 (Biologist) Camila Fuentes. Universidad de Valparaiso
2023 (Medical technologist) Camila León, Melany Muñoz, Camila Garay, Tamara Mendoza, Ignacio Rojas. Universidad de Valparaiso
MsC
2013-2014 (MSc in Biotechnology) Oriana Ramírez Herrera. Universidad Andrés Bello
2014-2016 (MSc in Neuroscience) Carolina Flores Muñoz. Universidad de Valparaíso.
2016-2017 (MSc in Neuroscience) Luis Manriquez Cockbaine. Universidad de Valparaíso.
2021-2023 (MSc in Cellular & Molecular Biology) Gonzalo Poblete. Universidad de Valparaíso.
PhD
2018-2022 (PhD in Neuroscience) Carolina Flores Muñoz. Universidad de Valparaíso.
2018-2022 (PhD in Neuroscience) Francisca García Rojas. Universidad de Valparaíso.
2019-2023 (PhD in Neuroscience) Paula Mujica Covarrubias. Universidad de Valparaíso.
2020-2023 (PhD in Neuroscience) Claudia García. Universidad de Valparaíso.
2020- (PhD in Neuroscience) Javiera Illanes. Universidad de Valparaíso.
2022- (PhD in Neuroscience) Stefany Órdenes. Universidad de Valparaíso.

Postdoctoral fellow FONDECYT

FONDECYT

Chile, 2013

Role of pannexin1 in synaptic physiology. ID 3130759 This grant seeks to investigate the role of pannexin1 in synaptic function and plasticity in the hippocampus from mice.
Inserción de Capital Humano Avanzado en la Academia CONICYT

COMISION NACIONAL DE INVESTIGACION CIENTIFICA Y TECNOLOGICA

Chile, 2015

Panexina 1: un nuevo actor en los mecanismos patológicos asociados a la enfermedad de Alzheimer. ID 79150045
CINV Postdoctoral fellowship

Centro Interdisciplinario de Neurociencia de valparaiso

Chile, 2012

The purpose of this program is to support outstanding and highly motivated PhD graduates from any country who wish to initiate or continue a scientific project in one of CINV’s labs.


The antiseizure medication valproate increases hemichannel activity found in brain cells, which could worsen disease outcomes Garcia-Rodriguez, Claudia; Duarte, Yorley; Ardiles, Alvaro O.; Saez, Juan C. Article ISI JOURNAL OF NEUROCHEMISTRY (2024)
A centronuclear myopathy-causing mutation in dynamin-2 disrupts neuronal morphology and excitatory synaptic transmission in a murine model of the disease Arriagada-Diaz, Jorge; Flores-Munoz, Carolina; Gomez-Soto, Barbara; Labrana-Allende, Marjorie; Mattar-Araos, Michelle; Prado-Vega, Lorena; Hinostroza, Fernando; Gajardo, Ivana; Guerra-Fernandez, Maria Jose; Bevilacqua, Jorge A.; Cardenas, Ana M.; Bitoun, Marc; Ardiles, Alvaro O.; Gonzalez-Jamett, Arlek M. Article ISI NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2023)
mGluR-dependent plasticity in rodent models of Alzheimer's disease Valdivia, Gonzalo; Ardiles, Alvaro O.; Idowu, Abimbola; Salazar, Claudia; Lee, Hey-Kyoung; Gallagher, Michela; Palacios, Adrian G.; Kirkwood, Alfredo Article ISI FRONTIERS IN SYNAPTIC NEUROSCIENCE (2023)
Neurobiology of Disorganized Attachment: A Review of Primary Studies on Human Beings Arancibia, Marcelo; Lutz, Mariane; Ardiles, Alvaro; Fuentes, Camila Article ISI NEUROSCIENCE INSIGHTS (2023)
Pannexin-1 Modulates Inhibitory Transmission and Hippocampal Synaptic Plasticity Garcia-Rojas, Francisca; Flores-Munoz, Carolina; Santander, Odra; Solis, Pamela; Martinez, Agustin D.; Ardiles, Alvaro O.; Fuenzalida, Marco Article ISI BIOMOLECULES (2023)
Probenecid, an Old Drug with Potential New Uses for Central Nervous System Disorders and Neuroinflammation Garcia-Rodriguez, Claudia; Mujica, Paula; Illanes-Gonzalez, Javiera; Lopez, Araceli; Vargas, Camilo; Saez, Juan C.; Gonzalez-Jamett, Arlek; Ardiles, Alvaro O. Article ISI BIOMEDICINES (2023)
The unfolded protein response transcription factor XBP1s ameliorates Alzheimer's disease by improving synaptic function and proteostasis Duran-Aniotz, Claudia; Poblete, Natalia; Rivera-Krstulovic, Catalina; Ardiles, alvaro O.; Li Diaz-Hung, Mei; Tamburini, Giovanni; Sabusap, Carleen Mae P.; Gerakis, Yannis; Cabral-Miranda, Felipe; Diaz, Javier; Fuentealba, Matias; Arriagada, Diego; Munoz, Ernesto; Espinoza, Sandra; Martinez, Gabriela; Quiroz, Gabriel; Sardi, Pablo; Medinas, Danilo B.; Contreras, Darwin; Pina, Ricardo; V. Lourenco, Mychael; Ribeiro, Felipe C.; Ferreira, Sergio T.; Rozas, Carlos; Morales, Bernardo; Plate, Lars; Gonzalez-Billault, Christian; Palacios, Adrian G.; Hetz, Claudio Article ISI MOLECULAR THERAPY (2023)
The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal Neurons Flores-Munoz, Carolina; Garcia-Rojas, Francisca; Perez, Miguel A.; Santander, Odra; Mery, Elena; Ordenes, Stefany; Illanes-Gonzalez, Javiera; Lopez-Espindola, Daniela; Gonzalez-Jamett, Arlek M.; Fuenzalida, Marco; Martinez, Agustin D.; Ardiles, Alvaro O. Article ISI CELLS (2022)
The Transcranial Light Therapy Improves Synaptic Plasticity in the Alzheimer's Disease Mouse Model Buendia, Debora; Guncay, Tatiana; Oyanedel, Macarena; Lemus, Makarena; Weinstein, Alejandro; Ardiles, Alvaro O.; Marcos, Jose; Fernandes, Adriana; Zangaro, Renato; Munoz, Pablo Article ISI BRAIN SCIENCES (2022)
Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging Cabral-Miranda, Felipe; Tamburini, Giovanni; Martinez, Gabriela; Ardiles, Alvaro O.; Medinas, Danilo B.; Gerakis, Yannis; Hung, Mei-Li Diaz; Vidal, Rene; Fuentealba, Matias; Miedema, Tim; Duran-Aniotz, Claudia; Diaz, Javier; Ibaceta-Gonzalez, Cristobal; Sabusap, Carleen M.; Bermedo-Garcia, Francisca; Mujica, Paula; Adamson, Stuart; Vitangcol, Kaitlyn; Huerta, Hernan; Zhang, Xu; Nakamura, Tomohiro; Sardi, Sergio Pablo; Lipton, Stuart A.; Kennedy, Brian K.; Pablo Henriquez, Juan; Cesar Cardenas, J.; Plate, Lars; Palacios, Adrian G.; Hetz, Claudio Article ISI EMBO JOURNAL (2022)
A Multisubcellular Compartment Model of AMPA Receptor Trafficking for Neuromodulation of Hebbian Synaptic Plasticity Mihalas, Stefan; Ardiles, Alvaro; He, Kaiwen; Palacios, Adrian; Kirkwood, Alfredo Article ISI FRONTIERS IN SYNAPTIC NEUROSCIENCE (2021)
Acute Pannexin 1 Blockade Mitigates Early Synaptic Plasticity Defects in a Mouse Model of Alzheimer’s Disease Flores-Muñoz, Carolina; Gómez, Bárbara; Mery, Elena; Mujica, Paula; Gajardo, Ivana; Córdova, Claudio; Lopez-Espíndola, Daniela; Durán-Aniotz, Claudia; Hetz, Claudio; Muñoz, Pablo; Gonzalez-Jamett, Arlek M.; Ardiles, Álvaro O. Article ISI SCOPUS Frontiers in Cellular Neuroscience (2020)
Astaxanthin Counteracts Excitotoxicity and Reduces the Ensuing Increases in Calcium Levels and Mitochondrial Reactive Oxygen Species Generation García, Francisca; Lobos, Pedro; Ponce, Alejandra; Cataldo, Karla; Meza, Daniela; Farías, Patricio; Estay, Carolina; Oyarzun-Ampuero, Felipe; Herrera-Molina, Rodrigo; Paula-Lima, Andrea; Ardiles, Álvaro O.; Hidalgo, Cecilia; Adasme ,Tatiana; Muñoz, Pablo Article Marine Drugs (2020)
Dynamin Superfamily at Pre- and Postsynapses: Master Regulators of Synaptic Transmission and Plasticity in Health and Disease Arriagada-Diaz, Jorge; Prado-Vega, Lorena; Cardenas Diaz, Ana M.; Ardiles, Alvaro O.; Gonzalez-Jamett, Arlek M. Article ISI NEUROSCIENTIST (2020)
Evidence of Synaptic and Neurochemical Remodeling in the Retina of Aging Degus Chang, Lily Y.-L.; Ardiles, Alvaro O; Tapia-Rojas, Cheril; Araya, Joaquin; Inestrosa, Nibaldo C.; Palacios, Adrian G.; Acosta, Monica L. Article ISI SCOPUS Frontiers in Neuroscience (2020)
Redox modifications in synaptic components as biomarkers of cognitive status, in brain aging and disease Munoz, Pablo; Ardiles, Alvaro O; Perez-Espinosa, Boris; Nunez-Espinosa, Cristian; Paula-Lima, Andrea; Gonzalez-Billault, Christian; Espinosa-Parrilla, Yolanda Article ISI MECHANISMS OF AGEING AND DEVELOPMENT (2020)
Lack of Pannexin 1 Alters Synaptic GluN2 Subunit Composition and Spatial Reversal Learning in Mice Gajardo, Ivana; Salazar, Claudia S.; Lopez-Espindola, Daniela; Estay, Carolina; Flores-Munoz, Carolina; Elgueta, Claudio; Gonzalez-Jamett, Arlek M.; Martinez, Agustin D.; Munoz, Pablo; Ardiles, Alvaro O Article ISI SCOPUS FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
IRE1 signaling exacerbates Alzheimer's disease pathogenesis Duran-Aniotz, Claudia; Cornejo, Victor Hugo; Espinoza, Sandra; Ardiles, Álvaro O.; Medinas, Danilo B.; Salazar, Claudia; Foley, Andrew; Gajardo, Ivana; Thielen, Peter; Iwawaki, Takao; Scheper, Wiep; Soto, Claudio; Palacios, Adrian G.; Hoozemans, Jeroen J. M.; Hetz, Claudio Article ISI SCOPUS ACTA NEUROPATHOLOGICA (2017)
Molecular and Cellular Mechanisms of Synaptopathies Ardiles, Alvaro O.; Grabrucker, Andreas M.; Scholl, Francisco G.; Rudenko, Gabby; Borsello, Tiziana Article SCOPUS Neural Plasticity (2017)
Genetic variants associated with neurodegenerative Alzheimer disease in natural models Álvaro O Ardiles; John, Ewer; Adrian G Palacios; Claudia Salazar; Gonzalo Valdivia Article ISI SCIELO BIOLOGICAL RESEARCH (2016)
Inhibition of DNA Methylation Impairs Synaptic Plasticity during an Early Time Window in Rats Muñoz, P; Estay, C; Diaz, P; Elgueta, C; Ardiles, AO; Lizana, PA Article ISI SCOPUS NEURAL PLASTICITY (2016)
Metabotropic Glutamate Receptors Induce a Form of LTP Controlled by Translation and Arc Signaling in the Hippocampus Wang, H.; Ardiles AO; Yang S.; Tran, T; Posada-Duque, R; Valdivia G.; Baek, M; Chuang, YA; Palacios, AG; Gallagher, M.; Worley, P; Kirkwood A. Article ISI SCOPUS JOURNAL OF NEUROSCIENCE (2016)
Regulation of Memory Formation by the Transcription Factor XBP1 Martinez, G; Vidal, RL; Mardones P.; Serrano, FG; Ardiles AO; Wirth C.; Valdés P.; Thielen P; Schneider, BL; Kerr, B.; Valdes, JL; Palacios, AG; Inestrosa, NC; Glimcher, LH; hetz C. Article ISI SCOPUS CELL REPORTS (2016)
Age Progression of Neuropathological Markers in the Brain of the Chilean Rodent Octodon degus, a Natural Model of Alzheimer's Disease Inestrosa, NC; Rios, JA; Cisternas P.; Tapia-Rojas, C; Rivera, DS; Braidy, N; Zolezzi, JM; Godoy JA; Carvajal, FJ; Ardiles AO; Bozinovic F.; Palacios, AG; Sachdev, PS Article ISI SCOPUS Brain Pathology (2015)
Alzheimer's Disease-Related Protein Expression in the Retina of Octodon degus Du, Lucia Y.; Chang, Lily Y-L.; Ardiles, Alvaro O; Tapia-Rojas, Cheril; Araya, Joaquin; Inestrosa, Nibaldo C; Palacios, Adrian G; Acosta, Monica L.; Padmanabhan, Jaya Article ISI SCOPUS PLOS ONE (2015)
Pannexin 1 regulates bidirectional hippocampal synaptic plasticity in adult mice Ardiles, AO, Flores C, Ahumada J, Monyer H, Cárdenas, AM, Palacios AG, Muñoz-Carvajal P, Sáez JC, Fuenzalida M, Martínez AD. Article ISI SCOPUS FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Integrity of mGluR-LTD in the Associative/Commissural Inputs to CA3 Correlates with Successful Aging in Rats Yang S.; Megill, A; Ardiles AO; Ransom S.; Tran, T; Koh, MT; Lee, HK; Gallagher, M.; Kirkwood A. Article ISI SCOPUS Journal of Neuroscience (2013)
Octodon degus (Molina 1782): A model in comparative biology and biomedicine Ardiles A, Ewer J, Acosta ML, Kirkwood A, Martinez A, Ebensperger LA, Bozinovic F, Lee T, Palacios AG Article SCOPUS Cold Spring Harbor Protocols (2013)
Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease Ardiles, A. O.; Tapia-Rojas C.C.; Mandal M; Alexandre F; Kirkwood A.; Inestrosa, N. C.; Palacios A.G. Article ISI SCOPUS Proceedings of the National Academy of Sciences of the United States of America (2012)
Pull-Push Neuromodulation of LTP and LTD Enables Bidirectional Experience-Induced Synaptic Scaling in Visual Cortex Huang S.; Trevino, M; He, K; Ardiles, A; dePasquale R.; Guo, Y; Palacios, A; Huganir, R; Kirkwood A. Article ISI SCOPUS Neuron (2012)
The elusive crypt olfactory receptor neuron: evidence for its stimulation by amino acids and cAMP pathway agonists Vielma, A; Ardiles, A; Delgado L.; Schmachtenberg, O. Article ISI SCOPUS JOURNAL OF EXPERIMENTAL BIOLOGY (2008)
Calcium channel subtypes differentially regulate fusion pore stability and expansion Ardiles AO; Gonzalez-Jamett AM; Maripillán J; Naranjo, D; Caviedes P.; Cárdenas AM Article ISI SCOPUS JOURNAL OF NEUROCHEMISTRY (2007)
A rapid exocytosis mode in chromaffin cells with a neuronal phenotype Ardiles AO; Maripillán J; Lagos, VL; Toro, R; Mora, IG.; Villarroel L.; Ales, E; Borges R.; Cárdenas AM Article ISI SCOPUS JOURNAL OF NEUROCHEMISTRY (2006)


Transcranial Red LED Therapy: A Promising Non-Invasive Treatment to Prevent Age-Related Hippocampal Memory Impairment. Jara, C.; Buendía, D.; Ardiles, A., Muñoz, P.; and Tapia-Rojas, C. BookSection (2021)
Redox Homeostasis in Neural Plasticity and the Aged Brain Muñoz, Pablo; García, Francisca; Estay, Carolina; Arias, Alejandra; Hidalgo, Cecilia; Ardiles, Alvaro O.; Erkekoglu, P?nar; Kocer-Gumusel, Belma BookSection (2016)


Therapeutic hypothermia reduces hypoxia-mediated brain injury in male offspring from experimental preeclampsia. Role of brain vascular response and endothelial VEGF/VEGFR2/NO signaling pathway Escudero, Carlos A.; Ardiles, Alvaro O Proyecto (2024)
Dynamin 2 contribution to the cytoskeleton-dependent synaptopathy on Alzheimer´s disease Gonzalez-Jamett, Arlek M.; Ardiles, Alvaro O Proyecto (2023)
Desarrollo de una cobertura cutánea costo efectiva “PanexpatchTM” para el tratamiento de úlceras venosas Martinez, Agustin D.; Ardiles, Alvaro O Proyecto (2021)
Over-activation of Panx1 in neurons leads to intracellular Ca2+ overload and subsequent defects in neuronal cytoskeleton and signaling receptor trafficking supporting synaptic defects in an Alzheimer´s disease model Alvaro Ardiles Araya; Gonzalez-Jamett, Arlek M.; MuÑoz, Pablo CÉsar Proyecto (2020)
Proteostaser-1: una terapia génica enfocada a disminuir la neurodegeneración y aumentar la función cognitiva en la enfermedad de Alzheimer Hetz, Claudio A.; Ardiles, Alvaro O Proyecto (2020)
Role of promigratory activation of VEGFR2 in the brain angiogenesis and its potential implication in learning and memory of offspring born to preeclampsia Escudero, Carlos Alonso; Ardiles, Alvaro Oscar Proyecto (2020)
Panexina 1=> un nuevo actor en los mecanismos patológios asociados a la enfermedad de Alzheimer PAI (79150045) Proyecto 2016-2018 Inv. Responsable
Proteostaser-1=> una terapia génica enfocada a disminuir la neurodegeneración y aumentar la función cognitiva en la enfermedad de Alzheimer. FONDEF (ID16I10223) Proyecto 2016-2018 Investigador(a)
A NOVEL ROLE OF PANNEXIN 1 CHANNELS IN THE SYNAPTOPATHY ASSOCIATED TO THE SOLUBLE AMYLOID ? OLIGOMERS IN ALZHEIMER´S DISEASE FONDECYT (11150776) Proyecto 2015-2018 Inv. Responsable
ASTAXANTINA Y ANTIENVEJECIMIENTO CEREBRAL CORFO (13IDL2-18271) Proyecto 2013-2016 Subdirector(a)
ROL DE PANEXIN 1 EN LA FISIOLOGIA SINAPTICA. FONDECYT (3130759) Proyecto 2012-2015 Inv. Responsable
Centro de neurociencia sensorial desde la señal de transducción hasta el código neural CONICYT (ACT45) Proyecto 2005-2007 Personal técnico y/o de apoyo
GENE DOSAGE EFFECTS IN CHOLINERGIC AND GLUTAMATERGIC DYSFUNCTION OF IMMORTALIZED NEURONAL CELLS DERIVED FROM THE TRISOMY 16 MOUSE, AN ANIMAL MODEL OF HUMAN DOWN SYNDROME FONDECYT (1040862) Proyecto 2004-2007 Personal técnico y/o de apoyo
CAMBIOS EN LA EFICIENCIA SECRETORA DEBIDO A REDISTRIBUCION DE ZONAS SECRETORAS ACTIVAS Y CANALES CALCIO EN CELULAS CROMAFINES DIFERENCIADAS FONDECYT (1020812) Proyecto 2002-2006 Personal técnico y/o de apoyo
CAMBIOS EN LA EFICIENCIA SECRETORA DEBIDO A REDISTRIBUCION DE ZONAS SECRETORAS ACTIVAS Y CANALES CALCIO EN CELULAS CROMAFINES DIFERENCIADAS FONDECYT (1020812) Proyecto 2002-2006 Tesista


Alzheimer's disease in the human eye. Clinical tests that identify ocular and visual information processing deficit as biomarkers Lowe J, Chang YL, Ardiles AO, Lim JC, Grey AC, Robertson KM, Danesh-Meyer HV, Palacios AG, Acosta ML. Review ISI SCOPUS Alzheimer's & Dementia (2014)
Role of Tau Protein in Neuronal Damage in Alzheimer's Disease and Down Syndrome Cárdenas A.M.; Ardiles, A. O.; Barraza, N; Baez-Matus X; Caviedes P. Review ISI SCOPUS Archives of Medical Research (2012)

Alvaro Ardiles

Full Professor

Medicine

Universidad de Valparaíso

Valparaiso, Chile

Adrian Palacios

Profesor

Instituto de Neurosciencia

UNIVERSIDAD DE VALPARAISO

Valparaiso, Chile

Carolina Flores

Investigador Postdoctoral

Neurociencias

Universidad de Valparaíso

Valparaíso, Chile

Claudia Duran-Aniotz

Profesor Asociado

Escuela de Psicología

Universidad Adolfo Ibánez

Santiago, Chile

Nibaldo Inestrosa

Full Professor

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

Ana Cárdenas

Professor

UNIVERSIDAD DE VALPARAÍSO

Valparaíso, Chile

Daniela López

Profesora Adjunta

UNIVERSIDAD DE VALPARAISO

Viña de Mar, Chile

Claudio Hetz

Deputy Director

INSTITUTO DE CIENCIAS BIOMÉDICAS, FACULTAD DE MEDICINA, UNIVERSIDAD DE CHILE

SANTIAGO, Chile

Cheril Tapia

Profesor Asistente

Facultad de Medicina y Ciencia

Universidad San Sebastián

Santiago, Chile

Pablo Caviedes

Full professor

ICBM

PROGRAMA DE FARMACOLOGÍA MOLECULAR Y CLÍNICA, ICBM, FAC. DE MEDICINA, U. DE CHILE

Santiago, Chile

Joaquìn Araya

Profesor Asistente

Facultad de Salud

Universidad Santo Tomás

Santiago, Chile

sandra espinoza

asistente de investigacion

Laboratorio Neuroinmunologia

Fundacion Ciencias para la Vida/Universidad San Sebastian

Santiago, Chile

Víctor Cornejo

Profesor Asistente

Facultad de Ciencias Biológicas

Pontificia Universidad Católica de Chile

Santiago, Chile

Claudio Cordova

Investigador asistente

Medicina

Universidad de Valparaíso

Valparaíso, Chile

John Ewer

Profesor titular

Neurociencia

UNIVERSIDAD DE VALPARAISO

Valparaiso, Chile

Maria Yolanda Espinosa

Full Professor

UNIVERSIDAD DE MAGALLANES

Punta Arenas, Chile

Alejandro Weinstein

Professor

Escuela de Ingenieria Civil Biomedica

Universidad de Valparaiso

Valparaiso, Chile

Francisco Carvajal

asistente de investigacion

Universidad de Magallanes

punta arenas, Chile

Christian Gonzalez

Full Professor

Biology

Universidad de Chile

Santiago, Chile

Juan Saez

Professor

Instituto de Neurociencias

Universidad de Valparaiso

Valparaíso, Chile

MIGUEL PEREZ

Associate Professor

Pontificia Universidad Catolica de Valparaiso

VALPARAISO, Chile

Andrea Paula-Lima

Assistant Professor

Institute for research in Dental Sciences

Universidad de Chile

Santiago, Chile

Paula Diaz

PhD (c)

Departamento de Fisiología

Pontificia Universidad Católica de Chile

Santiago, Chile

Arlek Gonzalez

INVESTIGADOR POST-DOCTORAL

CENTRO INTERDISCIPLINARIO DE NEUROCIENCIA, UNIVERSIDAD DE VALPARAISO

Valparaiso, Chile

Juan Godoy

Investigador

Centro de Oncologia dePrecision

Santiago, Chile

Juan Zolezzi

Associate Professor

School of Medicine

UNIVERSIDAD DE MAGALLANES

Punta Arenas, Chile

Marcelo Arancibia

Principal investigator

Universidad de Valparaíso

Viña del Mar, Chile

Pablo Muñoz

Profesor titular

Patología y Fisiología

UNIVERSIDAD DE VALPARAÍSO

Valparaiso, Chile

Agustin Martinez

Profesor Titular

Instituto de Neurociencia

UNIVERSIDAD DE VALPARAÍSO, CENTRO INTERDISCIPLINARIO DE NEUROCIENCIAS DE VALPARAÍSO

Valparaíso, Chile

Danilo Bilches

Staff Scientist

Instituto de Neurociencia Biomedica

Santiago, Chile

Pablo Lizana

Profesor Adjunto - Jornada Completa

Instituto de Biología

PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO

Valparaíso, Chile

Nora Lutz

Directora Departamento Salud Pública

Salud Pública

UNIVERSIDAD DE VALPARAISO

Valparaiso, Chile

Claudia Garcia

Candidata a doctora

Ciencias

Universidad de Valparaíso

Valparaíso, Chile

JUVENAL RÍOS

Investigador

CR de Investigación y Desarrollo

Instituto Nacional del Cáncer (INCANCER)

Santiago, Chile

Pablo Mardones

Research Associate

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Santiago, Chile

Alex Vielma

Postdoctoral researcher

Centro Interdisciplinario de Neurociencias de Valparaíso

Valparaiso, Chile

Luz Delgado

Investigador

Fundacion Ciencia para la vida

Chile

Pedro Cisternas

Investigador Asociado

Biología Celular

Pontificia Universidad Católica de Chile

Santiago, Chile

Francisco Bozinovic

Full professor

Ecology

Pontifical Catholic University of Chile

Santiago, Chile

Cristian Núñez

Profesor de Fisiología

Escuela de Medicina

Universidad de Magallanes

Punta Arenas, Chile

Oliver Schmachtenberg

Investigador titular

Instituto de Biología

Universidad de Valparaíso, CINV

Valparaíso, Chile

Débora Buendía

Académico - adjunto

Ingeniería Civil Biomédica

Universidad de Valparaíso

Valparaíso, Chile

YORLEY DUARTE

profesor Asistente

Universidad Andrés Bello

Santiago, Chile

David Naranjo

Profesor titular

Neurociencia

Universidad de Valparaíso

VALPARAISO, Chile

Alvaro Oscar Ardiles Araya

Líneas de Investigación

Educación

Neuroscience, UNIVERSIDAD DE VALPARAISO. Chile, 2011

Biochemist, PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO. Chile, 2006

Biochemistry, PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO. Chile, 2005

Experiencia Académica

Assistant professor Full Time

Lecturer professor Other

Full professor Full Time

Experiencia Profesional

Young associate researcher Part Time

Postdoctoral researcher Full Time

Lecturer professor Other

Research assistant Full Time

Adjunct researcher Part Time

Formación de Capital Humano

Premios y Distinciones

Postdoctoral fellow FONDECYT

Inserción de Capital Humano Avanzado en la Academia CONICYT

CINV Postdoctoral fellowship

Article (33)

BookSection (2)

Proyecto (15)

Panexina 1=> un nuevo actor en los mecanismos patológios asociados a la enfermedad de Alzheimer

Proteostaser-1=> una terapia génica enfocada a disminuir la neurodegeneración y aumentar la función cognitiva en la enfermedad de Alzheimer.

A NOVEL ROLE OF PANNEXIN 1 CHANNELS IN THE SYNAPTOPATHY ASSOCIATED TO THE SOLUBLE AMYLOID ? OLIGOMERS IN ALZHEIMER´S DISEASE

ASTAXANTINA Y ANTIENVEJECIMIENTO CEREBRAL

ROL DE PANEXIN 1 EN LA FISIOLOGIA SINAPTICA.

Centro de neurociencia sensorial desde la señal de transducción hasta el código neural

GENE DOSAGE EFFECTS IN CHOLINERGIC AND GLUTAMATERGIC DYSFUNCTION OF IMMORTALIZED NEURONAL CELLS DERIVED FROM THE TRISOMY 16 MOUSE, AN ANIMAL MODEL OF HUMAN DOWN SYNDROME

CAMBIOS EN LA EFICIENCIA SECRETORA DEBIDO A REDISTRIBUCION DE ZONAS SECRETORAS ACTIVAS Y CANALES CALCIO EN CELULAS CROMAFINES DIFERENCIADAS

CAMBIOS EN LA EFICIENCIA SECRETORA DEBIDO A REDISTRIBUCION DE ZONAS SECRETORAS ACTIVAS Y CANALES CALCIO EN CELULAS CROMAFINES DIFERENCIADAS

Review (2)