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Jose Ignacio Vargas Dominguez

Assistant Professor

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

DISEASES OF THE PANCREAS GASTROINTESTINAL AND HEPATOBILIARY ENDOSCOPY THERAPEUTIC ENDOSCOPY

MD, UNIVERSIDAD DE VALPARAISO. Chile, 2007
INTERNAL MEDICINE, UNIVERSIDAD DE VALPARAISO. Chile, 2007
GASTROENTEROLOGY, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2017
Therapeutic Endoscopy, UNIVERSITY OF TORONTO. Canada, 2020

FACULTY Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

MEDICINE

SANTIAGO, Chile

2017 - 2020
Assistant Professor Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

MEDICINE

Santiago, Chile

2020 - A la fecha

RESIDENT INTERNAL MEDICINE Full Time

HOSPITAL NAVAL DE VIÑA DEL MAR

VIÑA DEL MAR, Chile

2012 - 2015
RESIDENT GASTROENTEROLOGY Full Time

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

SANTIAGO, Chile

2015 - 2017
Faculty - Assistant Professor Full Time

Pontificia Universidad Católica de Chile

SANTIAGO, Chile

2017 - A la fecha

GASTROENTEROLOGY RESIDENCY SCHOLARSHIP

PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

Chile, 2015

GASTROENTEROLOGY RESIDENCY SCHOLARSHIP
Second best scientific presentation at the XXIV Congress of the Latin-American association for the study of the Liver (ALEH).

Latin-American association for the study of the Liver (ALEH)

Chile, 2016

“Comparative efficacy of an intensified re-vaccination scheme for hepatitis B virus infection among patients infected with HIV (CORE-HIV): a randomized controlled trial. Interim analysis”. Vargas JI, Jensen D, Martinez F, Sarmiento V, Acuña P, Peirano F, Fuster F.
Award for the best Chilean scientific abstract to the XXII Congress of the Latin-American association for the study of the Liver (ALEH)

Chilean Association of Hepatology.

Chile, 2014

“Serologic response to standard hepatitis B vaccination In HIVpositive patients”. Vargas JI, Fuster F, Jensen D, Sarmiento V, Peirano F, Acun?a P, Soto S, Jensen W, Ahumada R, Huilcaman M, Bruna M.
Best work presented by a Gastroenterology Fellow. XLIII Chilean Congress of Gastroenterology.

SOCIEDAD CHILENA DE GASTROENTEROLOGIA

Chile, 2016

“High frequency of pre-malignant gastric lesions and findings suggesting autoimmune gastritis detected through implementation of systematic gastric biopsies”. San Marti?n D*, Vargas JI*, Monrroy H, Torres J, Cruz R, Cabrera N, Zepeda G, Vidaurre J, Demandes H, Jime?nez C, Latorre G, Jime?nez M, Robles C, Roa JC, Candia R, Espino A, Gonzalez R, Riquelme A. (* Contributed equally).
Best work presented by a Gastroenterology Fellow. XLIV Chilean Congress of Gastroenterology. November 2017.

SOCIEDAD CHILENA DE GASTROENTEROLOGIA

Chile, 2017

“Antioxidant HDL function improves after sustained virological response in chronic HCV infected patients: dysfunctional HDL as possible new mechanism for HCV-associated high cardiovascular risk.” Vargas JI, Rivera K, Monrroy H, Labbe P, Arrese M, Benítez C, Barrera F, Wolff R, Norero B, Pino K, López-Lastra M, Rigotti A, Soza A.
Best original article published in the official journal of the Chilean Society of Gastroenterology “Gastroenterología Latinoamericana” ISSN 0716-8594.

SOCIEDAD CHILENA DE GASTROENTEROLOGIA

Chile, 2018

Vargas JI, Mansilla R, Mun?oz S, Roa JC, Walker K, Duarte I, Torres J, Meji?a R, Richter H, Gonza?lez R, Espino A. “Rapid on-site evaluation improves diagnostic accuracy of EUS-fine needle aspiration in solid pancreatic lesions”. Gastroenterol. latinoam 2017; Vol 28, Nº 2: 63-69. E-ISSN 0719-6822. (Article in Spanish).


Endoscopic hemostasis with hemoclips for post-variceal ligation bleeding ulcer Mansilla-Vivar R.; Vargas J.I.; Parra-Blanco A. Article SCOPUS VideoGIE (2020)
Enterocolonic fistula after endoscopic full-thickness resection of a peri-appendiceal orifice adenoma Ignacio Vargas, Jose; Rowsell, Corwyn; Mosko, Jeffrey D. Article ISI GASTROINTESTINAL ENDOSCOPY (2020)
Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12 Arab J.P.; Cabrera D.; Sehrawat T.S.; Jalan-Sakrikar N.; Verma V.K.; Simonetto D.; Cao S.; Yaqoob U.; Leon J.; Freire M.; Vargas J.I.; De Assuncao T.M.; Kwon J.H.; Guo Y.; Kostallari E.; Cai Q.; Kisseleva T.; Oh Y.; Arrese M.; Huebert R.C.; Shah V.H. Article ISI SCOPUS JOURNAL OF HEPATOLOGY (2020)
Infectious and non-infectious diseases burden among Haitian immigrants in Chile: a cross-sectional study Fuster, Francisco; Peirano, Felipe; Ignacio Vargas, Jose; Xavier Zamora, Francisco; Lopez-Lastra, Marcelo; Nunez, Ruth; Soza, Jacinta; Gonzalez, Katherine; Estay, Denisse; Barchiesi, Beatrice; Fuster, Antonieta; Lopez, Ignacia; Utrera, Nicolas; Landeros, Jorge; Chandia, Javiera; Paredes, Angela; Reyes, Daniela; Arias, Rodrigo; Padilla, Luis; Suarez, Hernan; Farcas, Katia; Cannistra, Macarena; Munoz, Geraldine; Rodriguez, Ignacio; Ormazabal, Ivana; Cortes, Josefina; Cornejo, Barbara; Manzur, Franco; Reyes, Antonia; Leiva, Vicente; Raimann, Maria Victoria; Arrau, Catalina; Cox, Valentina; Soza, Alejandro Article ISI SCIENTIFIC REPORTS (2020)
Management of Periappendiceal Orifice Polyps Vargas, Jose Ignacio; Teshima, Christopher W.; Mosko, Jeffrey D. Article ISI CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2020)
Response. Parra-Blanco, Adolfo; Monrroy, Hugo; Vargas, Jose Ignacio; Candia, Roberto; Gonzalez, Robinson Article Gastrointestinal endoscopy (2018)
Use of N-acetylcysteine plus simethicone to improve mucosalÂ visibility during upper GI endoscopy=> a double-blind, randomized controlled trial. Monrroy, Hugo; Vargas, Jose Ignacio; Glasinovic, Esteban; Candia, Roberto; Azúa, Emilio; Gálvez, Camila; Rojas, Camila; Cabrera, Natalia; Vidaurre, Josefa; Álvarez, Natalia; González, Jessica; Espino, Alberto; González, Robinson; Parra-Blanco, Adolfo Article Gastrointestinal endoscopy (2018)
[Direct antivirals for the treatment of chronic hepatitis C virus infection. Experience in 106 patients]. Vargas, José Ignacio; Arab, Juan Pablo; Monrroy, Hugo; Labbé, Pilar; Sarmiento, Valeska; Fuster, Felipe; Barrera, Francisco; Benitez, Carlos; Arrese, Marco; Fuster, Francisco; Soza, Alejandro Article Revista medica de Chile (2017)
Letter=> sublingual dosing of tacrolimus in transplant patients-interesting concept to overcome first pass effects. Authors' reply. Benítez, C; Vargas, J I; Solari, S Article Alimentary pharmacology & therapeutics (2017)
Sublingual tacrolimus administration provides similar drug exposure to per-oral route employing lower doses in liver transplantation=> a pilot study. Solari, S; Cancino, A; Wolff, R; Norero, B; Vargas, J I; Barrera, F; Guerra, J F; Martínez, J; Jarufe, N; Soza, A; Arrese, M; Benitez, C Article Alimentary pharmacology & therapeutics (2017)
Use of Statins in Patients with Chronic Liver Disease and Cirrhosis=> Current Views and Prospects. Vargas, Jose Ignacio; Arrese, Marco; Shah, Vijay H; Arab, Juan Pablo Article Current gastroenterology reports (2017)
Achieving protection against HBV in HIV patients=> Finding the best strategy Vargas, JI; Arab, JP; Jensen, D; Fuster, F Article HUMAN VACCINES IMMUNOTHERAPEUTICS (2016)
Achieving protection against HBV in HIV patients=> Finding the best strategy. Vargas, Jose Ignacio; Arab, Juan Pablo; Jensen, Daniela; Fuster, Francisco Article Human vaccines & immunotherapeutics (2016)
CD4/CD8 ratio as a predictor of the response to HBV vaccination in HIV-positive patients=> A prospective cohort study. Fuster, Francisco; Vargas, Jose Ignacio; Jensen, Daniela; Sarmiento, Valeska; Acuña, Pedro; Peirano, Felipe; Fuster, Felipe; Arab, Juan Pablo; Martínez, Felipe Article Vaccine (2016)
Presence of anti-HBc is associated to high rates of HBV resolved infection and low threshold for Occult HBV Infection in HIV patients with negative HBsAg in Chile Vargas, JI; Jensen, D.; Sarmiento, V; Peirano F.; Acuna P.; Fuster, F; Soto,S; Ahumada R.; Huilcaman M.; Bruna M.; Jensen W. Article ISI SCOPUS JOURNAL OF MEDICAL VIROLOGY (2016)
Presence of anti-HBc is associated to high rates of HBV resolved infection and low threshold for Occult HBV Infection in HIV patients with negative HBsAg in Chile Vargas JI, Jensen; D., Sarmiento V.; Peirano F., Acuna P.; Fuster F., Soto; S, Ahumada R.; Huilcaman M., Bruna M. Article Journal of Medical Virology (2016)
Presence of anti-HBc is associated to high rates of HBV resolved infection and low threshold for Occult HBV Infection in HIV patients with negative HBsAg in Chile. Vargas, Jose Ignacio; Jensen, Daniela; Sarmiento, Valeska; Peirano, Felipe; Acuña, Pedro; Fuster, Felipe; Soto, Sabrina; Ahumada, Rodrigo; Huilcaman, Marco; Bruna, Mario; Jensen, Werner; Fuster, Francisco Article Journal of medical virology (2016)
Black hairy tongue during interferon therapy for hepatitis C. Arab, Juan P; Vargas, José I; Morales, Carolina; Arrese, Marco Article Annals of hepatology (0)
Serum cytokeratin-18 fragment levels as noninvasive marker of nonalcoholic steatohepatitis in the chilean population. Arab, Juan Pablo; Hernández-Rocha, Cristián; Morales, Carolina; Vargas, José Ignacio; Solís, Nancy; Pizarro, Margarita; Robles, Camila; Sandoval, Daniela; Ponthus, Simon; Benítez, Carlos; Barrera, Francisco; Soza, Alejandro; Riquelme, Arnoldo; Arrese, Marco Article Gastroenterologia y hepatologia (0)


Positive Response to Hepatitis B Virus Standard Vaccination Scheme Among Patients in an HIV Program Fuster, F; Vargas, JI; Jensen, D.; Sarmiento, V; Peirano F.; Acuna P.; Soto,S; Jensen W.; Ahumada R.; Huilcaman M.; Bruna M. Abstract ISI HEPATOLOGY (2014)


Capítulo 23. Lesiones quísticas del páncreas Vargas, José Ignacio; Espino, Alberto BookSection (2020)


Black hairy tongue during interferon therapy for hepatitis C Arab, JP; Vargas, JI; Morales C. ; Arrese M. EditorialMaterial ISI ANNALS OF HEPATOLOGY (2015)


Use of N-acetylcysteine plus simethicone to improve mucosal visibility during upper GI endoscopy Response Parra-Blanco, A; Monrroy, H.; Vargas, JI; candia, r; Gonzalez, R Letter ISI SCOPUS GASTROINTESTINAL ENDOSCOPY (2018)


Hepatitis B virus (HBV) infection in Haitian immigrants in Chile=> Determination of HBV genotypes, viral escape mutants and host factors influencing response to vaccination FONDECYT (1191389) Proyecto 2019-2020 Coinvestigador(a)
Determinación de prevalencia de hepatitis b, hepatitis c y virus de inmunodeficiencia humana en dona ntes de sangre diferidos en bancos de sangre por conductas de riesgo. FONIS (SA16I0134) Proyecto 2017-2019 Investigador(a)
CARACTERIZACIÓN DE CAMBIOS LIPÍDICOS PLASMÁTICOS Y MODIFICACIÓN DE RIESGO CARDIOVASCULAR EN INDIVIDUOS CON INFECCIÓN CRÓNICA POR VIRUS DE HEPATITIS C TRATADOS CON NUEVOS ANTIVIRALES DIRECTOS Dirección de Investigación de la Escuela de Medicina Pontificia Universidad Católica de Chile (PB-20/16) Proyecto 2015-2017 Inv. Principal
Eficacia comparativa de un esquema intensificado de revacunación para virus de hepatitis b en pacien tes infectados con virus de inmunodeficiencia humana (vih)=> ensayo clinico controlado. FONIS (SA14ID0129) Proyecto 2015-2017 Inv. Responsable
HEPATITIS C VIRUS EXPLOITS THE HEPATIC LIPID PATHWAYS=> ROLE OF NPC1L1 IN HCV INFECTION. FONDECYT (1130357) Proyecto 2013-2017 Tesista