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TOMÁS ANDRÉS ZAMBRANO COLOMA

RESEARCHER

ENVIRON SPA

SANTIAGO, Chile

FARMACOGENÉTICA, EPIGENÉTICA, BIOLOGÍA TUMORAL

Biología Celular y Molecular, UNIVERSIDAD DE SAO PAULO. Chile, 2015


A New Insight for the Identification of Oncogenic Variants in Breast and Prostate Cancers in Diverse Human Populations, With a Focus on Latinos Armendariz-Castillo, Isaac; Guerrero, Santiago Article ISI FRONTIERS IN PHARMACOLOGY (2021)
Effect of statins on lipid metabolism-related microRNA expression in HepG2 cells Cerda, Alvaro; Salazar, Luis Article ISI PHARMACOLOGICAL REPORTS (2021)
MicroRNA-33b is a Potential Non-Invasive Biomarker for Response to Atorvastatin Treatment in Chilean Subjects With Hypercholesterolemia: A Pilot Study Ubilla, Carmen Gloria; Angulo, Jeremy; Obreque, Ignacio Article ISI FRONTIERS IN PHARMACOLOGY (2021)
Atorvastatin Increases the Expression of Long Non-Coding RNAs ARSR and CHROME in Hypercholesterolemic Patients: A Pilot Study Paez, Isis; Prado, Yalena; Ubilla, Carmen G. Article ISI PHARMACEUTICALS (2020)
Circulating miRNA-23b and miRNA-143 Are Potential Biomarkers for In-Stent Restenosis Rebolledo, Camilo; Bustos, Luis; Bobadilla, Braulio; Lanas, Fernando Article ISI BIOMED RESEARCH INTERNATIONAL (2020)
Gender-Specific Association Between ABCC2-24C > T SNP and Reduction in Triglycerides in Chilean Patients Treated With Atorvastatin Prado, Y; Arencibia, A.; Zambrano, T Article ISI SCOPUS BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2018)
Statins differentially modulate microRNAs expression in peripheral cells of hyperlipidemic subjects: A pilot study Hirata, RDC; Hirata, MH Article ISI SCOPUS EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2018)
Transporter genes ABCG2 rs2231142 and ABCB1 rs1128503 polymorphisms and atorvastatin response in Chilean subjects Article ISI SCOPUS JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS (2018)
Bacterial Community Profile of the Gut Microbiota Differs between Hypercholesterolemic Subjects and Controls Article ISI SCOPUS BIOMED RESEARCH INTERNATIONAL (2017)
CYP2C19*2 Polymorphism in Chilean Patients with In-Stent Restenosis Development and Controls Article ISI SCOPUS BIOMED RESEARCH INTERNATIONAL (2017)
Epigenetic Modifications of Major Depressive Disorder Saavedra, Kathleen; Molina-Marquez, Ana; Saavedra, Nicolás; Salazar, Luis. Article INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
HMGCR rs17671591 SNP Determines Lower Plasma LDL-C after Atorvastatin Therapy in Chilean Individuals Cuevas, Alejandro; Fernandez, C; Ferrada, L; Zambrano, Tomás; Rosales, Alexis; Saavedra, N; Salazar, Luis. Article Basic and clinical pharmacology and toxicology (2016)
Polyphenol-Rich Extract from Propolis Reduces the Expression and Activity of Streptococcus mutans Glucosyltransferases at Subinhibitory Concentrations Saavedra, N; Alvear, M; Zambrano, T; Barrientos, L; Salazar, L.A. Article ISI SCOPUS BIOMED RESEARCH INTERNATIONAL (2016)
Altered microRNome Profiling in Statin-Induced HepG2 Cells: A Pilot Study Identifying Potential new Biomarkers Involved in Lipid-Lowering Treatment Zambrano, T; Hirata, RDC; Hirata, MH; Cerda A. Article ISI SCOPUS Cardiovascular Drugs and Therapy (2015)
APOE Polymorphisms Contribute to Reduced Atorvastatin Response in Chilean Amerindian Subjects Lagos, J.; Zambrano, T; Rosales A. Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Efficacy of Ezetimibe Is Not Related to NPC1L1 Gene Polymorphisms in a Pilot Study of Chilean Hypercholesterolemic Subjects Zambrano, T; Saavedra, N; Lanas F.; Caamano J Article ISI SCOPUS Molecular Diagnosis and Therapy (2015)
Impact of 3’UTR genetic variants in PCSK9 and LDLR genes on plasma lipid traits and response to atorvastatin in Brazilian subjects: A pilot study Zambrano, T; Cerda A.; Pinto, G. A.; Salazar, L.A. Article SCOPUS International Journal of Clinical and Experimental Medicine (2015)
SLCO1B1 c.388A > G Polymorphism Is Associated with HDL-C Levels in Response to Atorvastatin in Chilean Individuals Prado, Y; Saavedra, N; Zambrano, T; Lagos, J.; Rosales A. Article ISI SCOPUS INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Influence of SREBP-2 and SCAP Gene Polymorphisms on Lipid-Lowering Response to Atorvastatin in a Cohort of Chilean Subjects with Amerindian Background Lagos, J.; Zambrano, T; Rosales A. Article ISI SCOPUS MOLECULAR DIAGNOSIS & THERAPY (2014)
Effect of Five Single Nucleotide Polymorphisms of ABCG5 and ABCG8 Genes on Ezetimibe Lipid-Lowering Response Caamaño, José M; Saavedra, Nicolás; Zambrano, Tomás; Lanas, Fernando; Salazar, Luis A. Article ISI SCIELO International Journal of Morphology (2012)
Identification of pharmacogenetic predictors of lipid-lowering response to atorvastatin in Chilean subjects with hypercholesterolemia Rosales A.; Alvear, M; Cuevas, A.; Saavedra, N; Zambrano, T; Salazar, L.A. Article ISI SCOPUS CLINICA CHIMICA ACTA (2012)
Frequency of Common Variants in Genes Involved in Lipid-Lowering Response to Statins in Chilean Subjects with Hypercholesterolemia Rosales A.; Pacheco A.; Cuevas, A.; Saavedra, N; Zambrano, T; Lanas F. Article ISI SCIELO International Journal of Morphology (2011)
Frequency of common variants in genes involved in lipid-lowering response to statins in Chilean subjects with hypercholesterolemia Frecuencia de polimorfismos en genes relacionados a la respuesta terapéutica a estatinas en individuos Chilenos con hipercolesterolemia Rosales A.; Pacheco A.; Cuevas, A.; Saavedra, N; Zambrano, T; Salazar, L.A.; Lanas F. Article SCOPUS INTERNATIONAL JOURNAL OF MORPHOLOGY (2011)
Polimorfismo SNP-43 del gen de Calpaína-10 en individuos con enfermedad coronaria y controles Cuevas, Alejandro; Zambrano, Tomás; Márquez, José Luis; Hernández, Alfonso; Saavedra, Nicolás; Jaramillo, Priscilla; Caamaño, José; Lanas, Cecilia; Lanas, Fernando; Salazar, Luis Article SCIELO Revista chilena de cardiologï¿½a (2010)


Differentially expressed microRNAs in human peripheral blood mononuclear cells are potential markers for statin response Salazar, L; Zambrano, T; Hirata, M; Cerda A.; Hirata, RDC Abstract ISI EUROPEAN HEART JOURNAL (2015)
PCSK9 23968 A > G gene polymorphism in chilean individuals with coronary artery disease and controls Zambrano, T; Jaramillo, P; Lanas, C; Lanas F. Abstract ISI ATHEROSCLEROSIS SUPPLEMENTS (2007)


PCSK9 polymorphism rs505151 affects lipid-lowering response to atorvastatin but does not influence ezetimibe therapy in Chilean subjects Zambrano, T; Caamano, JM; Rosales A.; Saavedra, N; Lanas F. ConferencePaper ISI CORONARY ARTERY DISEASE: 2011 UPDATE: FROM PREVENTION TO INTERVENTION (2011)


EFFECTS OF LIPID-LOWERING THERAPY WITH ATORVASTATIN ON MICRORNA EXPRESSION SIGNATURE IN MONONUCLEAR CELLS FROM HYPERCHOLESTEROLEMIC PATIENTS FONDECYT (1130675) Proyecto 2013-2016 Coinvestigador(a)
Farmacogenômica de estatinas=> Regulação do perfil de expressão de miRNAs e genes alvo em células HepG2 CNPq (473485/2012-5) Proyecto 2012-2015 Coinvestigador(a)
Papel de estatinas na modulação de miRNAs em células mononucleares de pacientes hipercolesterolêmicos FAPESP (11/21967-1) Proyecto 2012-2014 Coinvestigador(a)


The Current State of MicroRNAs as Restenosis Biomarkers Salazar, L.A. Review ISI SCOPUS (2020)
Involvement of cytochrome P450 in cisplatin treatment: implications for toxicity Quintanilha J.C.F.; de Sousa V.M.; Visacri M.B.; Amaral L.S.; Santos R.M.M.; Moriel P. Review ISI SCOPUS CANCER CHEMOTHERAPY AND PHARMACOLOGY (2017)
Medicinal value of the Berberis genus as hypoglycemic agent Furrianca, MC; Alvear, M; Zambrano, T; Barrientos, L; Fajardo, V Review ISI BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS (2015)
Medicinal value of the Berberis genus as hypoglycemic agent [Valor medicinal del género Berberis como agente hipoglicemiante] Alvear, M; Zambrano, T; Barrientos, L; Fajardo, V; Salazar, L.A. Review SCOPUS Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas (2015)