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Manuel Isaías Osorio Soto

Docente

UNIVERSIDAD DIEGO PORTALES

Santiago, Chile

Worked in enzyme catalysis models, with Glucansucrase and Xenobiotic reductase A/B models. In my work used molecular dynamics simulation (MM) for study the ligand protein interaction and quantum mechanics (QM).

Molecular Physical Chemistry, UNIVERSIDAD ANDRES BELLO. Chile, 2018
Biochemistry, PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO. Chile, 2005

DOCENTE Part Time

UNIVERSIDAD DIEGO PORTALES

MEDICINA

SANTIAGO, Chile

2007 - 2014

postdoctoral researcher Part Time

UNIVERSIDAD ANDRES BELLO

Santiago, Chile

2018 - 2019


Search for Novel Potent Inhibitors of the SARS-CoV-2 Papain-like Enzyme: A Computational Biochemistry Approach Osorio, Manuel, I; Osvaldo Yañez; Mauricio Gallardo; Zúñiga-Bustos, Matías; Jorge Mulia-Rodríguez; Roberto López-Rendón; Olimpo García-Beltrán; Fernando González-Nilo; Pérez-Donoso, José M. Article PHARMACEUTICALS (2022)
Exploring the structure-function relationship in a hypothetical membrane protein from a nucleotide sequence Osorio, Manuel, I; Salinas, Dino G. Article ISI BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION (2021)
In Silico Study of Coumarins and Quinolines Derivatives as Potent Inhibitors of SARS-CoV-2 Main Protease Yanez, Osvaldo; Osorio, Manuel Isaias; Uriarte, Eugenio; Areche, Carlos; Tiznado, William; Perez-Donoso, Jose M.; Garcia-Beltran, Olimpo; Gonzalez-Nilo, Fernando Article ISI FRONTIERS IN CHEMISTRY (2021)
Theobroma cacao L. compounds: Theoretical study and molecular modeling as inhibitors of main SARS-CoV-2 protease Yanez, Osvaldo; Osorio, Manuel Isaias; Areche, Carlos; Vasquez-Espinal, Alejandro; Bravo, Jessica; Sandoval-Aldana, Angelica; Perez-Donoso, Jose M.; Gonzalez-Nilo, Fernando; Matos, Maria Joao; Osorio, Edison; Garcia-Beltran, Olimpo; Tiznado, William Article ISI BIOMEDICINE & PHARMACOTHERAPY (2021)
Biotransformation of 2,4,6-Trinitrotoluene by Pseudomonas sp. TNT3 isolated from Deception Island, Antarctica Cabrera, Ma. Ángeles; Márquez, Sebastián L.; Quezada, Carolina P.; Osorio, Manuel, I; Castro-Nallar, Eduardo; González-Nilo, Fernando D.; Pérez-Donoso, José M. Article ISI SCOPUS Environmental Pollution (2020)
Odd Loop Regions of XenA and XenB Enzymes Modulate Their Interaction with Nitro-explosives Compounds and Provide Structural Support for Their Regioselectivity Osorio M.I.; Cabrera M.A.; GonzÃ¡lez-Nilo F.; PÃ©rez-Donoso J.M. Article ISI SCOPUS JOURNAL OF CHEMICAL INFORMATION AND MODELING (2019)
The most probable number of blocks for the partitions of the set of codons could have determined the number of standard amino acids Salinas, D.G.; Gallardo, M.O.; Osorio M.I. Article ISI SCOPUS BioSystems (2012)
Visualization of infectious pancreatic necrosis virus (IPNV) particles labeled with fluorescent probes Osorio, M; Espinoza, JC; Kuznar, J Article ISI SCOPUS JOURNAL OF VIROLOGICAL METHODS (2005)