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Juan Enrique Tichauer Calderón

Bioquímico

Pontificia Universidad Católica de Chile

Santiago, Chile

Líneas de Investigación


Role of microglia in neurodegenerative diseases Role of innate immune system in multiple sclerosis Immunopathogenesis of autoimmune diseases Regulation of immune response Role of astrocyte connexins in brain injury

Educación

  •  Doctor en Ciencias Médicas, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2011
  •  Bioquímico, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE. Chile, 2005

Experiencia Académica

  •   postdoctorado FONIS 1100356 Other

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Santiago, Chile

    2010 - 2011

  •   postdoctorado FONDEF D08I1087 Other

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Santigo, Chile

    2010 - 2011

  •   candidato a doctor FONDECYT 1090353 Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Chile

    2009 - 2010

  •   candidato a doctor FONDECYT 1040831 Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Chile

    2006 - 2007

  •   Tesista grado bioquímico FONDECYT 1030415 Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Chile

    2004 - 2007

  •   Investigador FONDECYT 1110523 Full Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Chile

    2012 - 2013

  •   Postdoctorado FONDECYT de postdoc 3150133 Full Time

    UNIVERSIDAD DE CHILE

    Medicina

    Chile

    2015 - 2017

  •   Investigador Fondef-IDEAID16I10258 Part Time

    UNIVERSIDAD DE CHILE

    Medicina

    Santiago, Chile

    2017 - 2019

  •   Técnico Fondecyt 11171155 Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Santiago, Chile

    2018 - A la fecha

  •   Técnico FONDECYT 1190620. Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Ciencias Biológicas

    Santiago, Chile

    2019 - A la fecha

  •   Técnico Fondecyt inicio 11171155 Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Medicina

    Santiago, Chile

    2018 - 2020

  •   Técnico FONDECYT 1190620 Part Time

    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE

    Ciencias Biológicas

    Santiago, Chile

    2019 - A la fecha

Experiencia Profesional

  •   Bioquímico Fondecyt inicio 1117155 Other

    Pontificia Universidad Católica de Chile

    Santiago, Chile

    2018 - A la fecha

  •   Bioquímico Fondecyt 1190620 Other

    Pontificia Universidad Católica de Chile

    Santiago, Chile

    2019 - A la fecha


 

Article (14)

Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis.
Age-dependent changes on TGFbeta1 Smad3 pathway modify the pattern of microglial cell activation.
Identification of novel 11beta-HSD1 inhibitors by combined ligand- and structure-based virtual screening.
A New Presentation of the Chimeric CYP11B1/CYP11B2 Gene With Low Prevalence of Primary Aldosteronism and Atypical Gene Segregation Pattern
A new presentation of the chimeric CYP11B1/CYP11B2 gene with low prevalence of primary aldosteronism and atypical gene segregation pattern.
Scavenger receptor class A ligands induce secretion of IL1 beta and exert a modulatory effect on the inflammatory activation of astrocytes in culture
Scavenger receptor class A ligands induce secretion of IL1beta and exert a modulatory effect on the inflammatory activation of astrocytes in culture.
Transforming growth factor-beta stimulates beta amyloid uptake by microglia through Smad3-dependent mechanisms
Transforming growth factor-beta stimulates beta amyloid uptake by microglia through Smad3-dependent mechanisms.
Proliferating culture of aged microglia for the study of neurodegenerative diseases
Aging-dependent changes of microglial cells and their relevance for neurodegenerative disorders.
Modulation by astrocytes of microglial cell-mediated neuroinflammation=> effect on the activation of microglial signaling pathways.
Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse.
P450 CYP2C epoxygenase and CYP4A omega-hydroxylase mediate ciprofibrate-induced PPARalpha-dependent peroxisomal proliferation.

Abstract (2)

Dual activity of interferon gamma in experimental autoimmune encephalomyelitis
ACIDOSIS INDUCES CHANGES ON SCAVENGER RECEPTORS EXPRESSION PATTERN OF GLIAL CELLS: EFFECT ON CELL ADHESION AND PHAGOCYTOSIS OF ABETA
6
Juan Tichauer

Bioquímico

Medicina intensiva

Pontificia Universidad Católica de Chile

Santiago, Chile

4
Rommy von Bernhardi

Full Professor

Neurology

DEPT. NEUROLOGY, FAC. MEDICINE PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Carlos Lagos

Profesor Asociado

FACULTAD DE MEDICINA Y CIENCIA

UNIVERSIDAD SAN SEBASTIÁN

SANTIAGO, Chile

1
LILIAN REYES

Director de Escuela de Bioquímica

Universidad San Sebastián

Santiago, Chile

1
CLAUDIA CARCAMO

Profesor Asociado

neurology

PONTIFICIA UNIVERSIDADA CATÓLICA DE CHILE. DEPARTAMENTO DE NEUROLOGÍA

Santiago, Chile

1
Rodrigo Naves

Associate Professor

Program of Immunology

Universidad de Chile

Santiago, Chile

1
Carlos Fardella

Profesor Titular

Endocrinología

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Rene Baudrand

Profesor Asociado

Endocrinología

Pontificia Universidad Católica de Chile

Santiago, Chile

1
Cristian Carvajal

Associate Professor

Endocrinologia

PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE

Santiago, Chile

1
Paola Murgas

Profesor Investigador Asistente

Facultad de Ciencias

Universidad Austral de Chile

Valdivia , Chile

1
Pamela Trejo

Endocrinologist

Internal Medicine

Clinica Alemana Santiago

Santiago, Chile